1IDA

CRYSTAL STRUCTURES OF HIV-2 PROTEASE IN COMPLEX WITH INHIBITORS CONTAINING THE HYDROXYETHYLAMINE DIPEPTIDE ISOSTERE

Experimental procedure

Spacegroup name	P 43 21 2
Unit cell lengths	62.600, 62.600, 115.800
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	6.000 - 1.700
R-factor	0.196
Rwork	0.196
RMSD bond length	0.017
RMSD bond angle	2.600
Phasing software	X-PLOR
Refinement software	TNT

Data quality characteristics

	Overall
Number of reflections	22017 *
Completeness [%]	80.0 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Vapor diffusion, hanging drop *	5.4 *

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	drop	protein	6 (mg/ml)
2	1	drop	phosphate	10 (%(v/v))
3	1	drop		0.02 (%(w/v))
4	1	reservoir		0.3-0.5 (M)
5	1	reservoir	sodium acetate	0.1 (M)
6	1	reservoir		0.02 (%(w/v))