1D4Y

HIV-1 PROTEASE TRIPLE MUTANT/TIPRANAVIR COMPLEX

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	SIEMENS
Temperature [K]	298
Detector technology	AREA DETECTOR
Collection date	1995-06-28
Detector	SIEMENS
Spacegroup name	P 21 21 2
Unit cell lengths	59.785, 87.503, 46.458
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	10.000 - 1.970
R-factor	0.174
R-free	0.21600
Structure solution method	MOLECULAR REPLACEMENT
Data reduction software	X-GEN
Data scaling software	X-GEN
Phasing software	MERLOT
Refinement software	SHELXL-97

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	10.000	2.100
High resolution limit [Å]	1.970	1.970
Rmerge	0.075	0.317
<I/σ(I)>	21.96	3.12
Completeness [%]	90.0	66
Redundancy	7.23	3.9

Crystallization Conditions

crystal ID	method	pH	temperature	details
1		5.4		none *