9IXZ
 
 | | human KCNQ2-CaM-Ebio3 Complex in the Presence of PIP2 | | Descriptor: | Calmodulin-1, Isoform 3 of Potassium voltage-gated channel subfamily KQT member 2, ~{N}-[7-[bis(fluoranyl)methoxy]-1-prop-2-ynyl-indazol-3-yl]-2-propyl-pentanamide | | Authors: | Yang, Z, Guo, J. | | Deposit date: | 2024-07-29 | | Release date: | 2025-03-19 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Small molecule inhibits KCNQ channels with a non-blocking mechanism.
Nat.Chem.Biol., 21, 2025
|
|
9IY1
 | | P450 BS beta mutant F46A | | Descriptor: | DI(HYDROXYETHYL)ETHER, Fatty-acid peroxygenase, GLYCEROL, ... | | Authors: | Gong, P.Q, Gao, X. | | Deposit date: | 2024-07-29 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Unexpected Activities of CYP152 Peroxygenases Toward Non-carboxylic Substrates Reveal Novel Substrate Recognition Mechanism and Catalytic Versatility.
Angew.Chem.Int.Ed.Engl., 64, 2025
|
|
9IYW
 | | Crystal structure of chimeric KSQ-AT didomain | | Descriptor: | Polyketide synthase,GfsA KSQ-AncAT chimeric protein, SODIUM ION | | Authors: | Chisuga, T, Miyanaga, A. | | Deposit date: | 2024-07-31 | | Release date: | 2025-08-06 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Ancestral sequence reconstruction as a tool for structural analysis of modular polyketide synthases.
Nat Commun, 16, 2025
|
|
9J5P
 | |
9JFJ
 | | Crystal structure of the cytoplasmic domain of ZraS in ADP-bound form | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Sensor histidine kinase ZraS | | Authors: | Mahapatra, N, Pandey, S, Mahanta, P, Acharya, R. | | Deposit date: | 2024-09-04 | | Release date: | 2025-03-26 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Insights Into the Conformational Dynamics of the Cytoplasmic Domain of Metal-Sensing Sensor Histidine Kinase ZraS.
Proteins, 93, 2025
|
|
9JIT
 | |
9JIV
 | | Macrophage migration inhibitory factor Y100H mutant (MIF(Y100H)) | | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... | | Authors: | Himiyama, T, Okamoto, Y. | | Deposit date: | 2024-09-12 | | Release date: | 2025-08-06 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | A cytokine-based designer enzyme with an abiological multinuclear metal center exhibits intrinsic and extrinsic catalysis.
Nat Commun, 16, 2025
|
|
9JIY
 | |
9JIZ
 | |
9JJ0
 | |
9JJ9
 | | Class 3 state of the GfsA KSQ-ancestralAT chimeric didomain in complex with the GfsA ACP domain | | Descriptor: | N-[2-(acetylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, Polyketide synthase, Polyketide synthase GfsA | | Authors: | Chisuga, T, Liao, Z, Adachi, N, Kawasaki, M, Moriya, T, Senda, T, Kudo, F, Eguchi, T, Miyanaga, A. | | Deposit date: | 2024-09-13 | | Release date: | 2025-08-06 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (2.71 Å) | | Cite: | Ancestral sequence reconstruction as a tool for structural analysis of modular polyketide synthases.
Nat Commun, 16, 2025
|
|
9JJB
 | | Class 1 state of the GfsA KSQ-ancestralAT chimeric didomain in complex with the GfsA ACP domain | | Descriptor: | N-[2-(acetylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, Polyketide synthase, Polyketide synthase GfsA | | Authors: | Chisuga, T, Liao, Z, Adachi, N, Kawasaki, M, Moriya, T, Senda, T, Kudo, F, Eguchi, T, Miyanaga, A. | | Deposit date: | 2024-09-13 | | Release date: | 2025-08-06 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (2.68 Å) | | Cite: | Ancestral sequence reconstruction as a tool for structural analysis of modular polyketide synthases.
Nat Commun, 16, 2025
|
|
9JR4
 | | Crystal structure of RaTG13 receptor-binding domain complexed with squirrel ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | Authors: | Lan, J, Nan, X. | | Deposit date: | 2024-09-29 | | Release date: | 2025-08-06 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (2.76 Å) | | Cite: | Cross-species recognition of squirrel ACE2 by the receptor binding domains of SARS-CoV-2, RaTG13, PCoV-GD and PCoV-GX.
Structure, 2025
|
|
9JR5
 | | Crystal structure of PCoV-GD receptor-binding domain complexed with squirrel ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | Authors: | Lan, J, Nan, X. | | Deposit date: | 2024-09-29 | | Release date: | 2025-08-06 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (3.414 Å) | | Cite: | Cross-species recognition of squirrel ACE2 by the receptor binding domains of SARS-CoV-2, RaTG13, PCoV-GD and PCoV-GX.
Structure, 2025
|
|
9JR7
 | |
9JRC
 | | Crystal structure of SARS-CoV-2 receptor-binding domain complexed with squirrel ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | | Authors: | Lan, J, Nan, X. | | Deposit date: | 2024-09-29 | | Release date: | 2025-08-06 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (3.16 Å) | | Cite: | Cross-species recognition of squirrel ACE2 by the receptor binding domains of SARS-CoV-2, RaTG13, PCoV-GD and PCoV-GX.
Structure, 2025
|
|
9K3H
 | | Cryo-EM structure of the unliganded human melanocortin receptor 5 (MC5R)-Gs complex | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,HiBiT, Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Feng, W.B, Zhou, Q.T, Zheng, C, Yang, D.H, Wang, M.W. | | Deposit date: | 2024-10-18 | | Release date: | 2025-08-06 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Structural basis for the constitutive activity of the melanocortin receptor family.
Structure, 33, 2025
|
|
9KUD
 | |
9LK4
 | | Cryo-EM structure of Lhcb4.1-C2S2 PSII-LHCII supercomplex from Arabidopsis thaliana | | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | | Authors: | Zhou, Q, Caferri, R, Shan, J.Y, Amelii, A, Bassi, R, Liu, Z.F. | | Deposit date: | 2025-01-16 | | Release date: | 2025-06-18 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | A stress-induced paralog of Lhcb4 controls the photosystem II functional architecture in Arabidopsis thaliana.
Nat Commun, 16, 2025
|
|
9LK5
 | | The structure of Lhcb8-C2S2 PSII-LHCII supercomplex from Arabidopsis thaliana | | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | | Authors: | Zhou, Q, Caferri, R, Shan, J.Y, Amelii, A, Bassi, R, Liu, Z.F. | | Deposit date: | 2025-01-16 | | Release date: | 2025-06-18 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | A stress-induced paralog of Lhcb4 controls the photosystem II functional architecture in Arabidopsis thaliana.
Nat Commun, 16, 2025
|
|
9LO1
 | | Anti-CRISPR protein AcrIE7 | | Descriptor: | Anti-CRISPR AcrIE7 | | Authors: | Suh, J.Y, Park, C.K. | | Deposit date: | 2025-01-22 | | Release date: | 2025-06-18 | | Last modified: | 2025-08-13 | | Method: | SOLUTION NMR | | Cite: | Structural Investigation of the Anti-CRISPR Protein AcrIE7.
Proteins, 93, 2025
|
|
9LO2
 | | Crystal Structure of Anti-CRISPR protein | | Descriptor: | Anti-CRISPR protein, AcrIE7 | | Authors: | Kang, J, Bae, E, Lee, G, Koo, J, Oh, H. | | Deposit date: | 2025-01-22 | | Release date: | 2025-06-18 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (2.287 Å) | | Cite: | Structural Investigation of the Anti-CRISPR Protein AcrIE7.
Proteins, 93, 2025
|
|
9M3N
 | | Crystal structure of human TRIM21 PRYSPRY in complex with T-02 | | Descriptor: | 1-ethyl-~{N}-methyl-5-phenyl-~{N}-[3-[3-(trifluoromethyl)phenyl]cyclobutyl]pyrazole-4-carboxamide, E3 ubiquitin-protein ligase TRIM21 | | Authors: | Zhang, L.J, Zhang, L.Y. | | Deposit date: | 2025-03-03 | | Release date: | 2025-07-16 | | Last modified: | 2025-08-13 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | TRIM21-Driven Degradation of BRD4: Development of Heterobifunctional Degraders and Investigation of Recruitment and Selectivity Mechanisms.
J.Chem.Inf.Model., 65, 2025
|
|
9MF5
 | | CryoEM structure of the Protein Phosphatase 2A (Abeta-B56gamma-Calpha) holoenzyme complex | | Descriptor: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform, ... | | Authors: | Day, A, Taylor, D. | | Deposit date: | 2024-12-09 | | Release date: | 2025-07-09 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Regulatory mechanisms of PP2A complex assembly driven by physicochemical differences in A-subunit isoforms.
Structure, 2025
|
|
9MGB
 | | scFv antibody CL33 bound to R-phycoerythrin | | Descriptor: | CL33 scFv, PHYCOERYTHROBILIN, PHYCOUROBILIN, ... | | Authors: | Rashleigh, L, Gully, B.S. | | Deposit date: | 2024-12-10 | | Release date: | 2025-08-06 | | Last modified: | 2025-08-13 | | Method: | ELECTRON MICROSCOPY (2.1 Å) | | Cite: | Antibody-like recognition of a gamma delta T cell receptor toward a foreign antigen.
Structure, 2025
|
|
