9UYH
 
 | | Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 1 (Conformation 1) | | Descriptor: | Beta-arrestin-1, Chemerin-like receptor 2,Vasopressin V2 receptor, Nanobody 32, ... | | Authors: | Cai, H, Lin, X, Zhao, L, He, M, Yu, J, Zhang, B, Ma, Y, Xie, C, Shui, W, Zhao, Q, Zhu, Y, Wu, B. | | Deposit date: | 2025-05-15 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Noncanonical agonist-dependent and -independent arrestin recruitment of GPR1
Science, 2025
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9UYI
 | | Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 1 (Conformation 2) | | Descriptor: | Beta-arrestin-1, Chemerin-like receptor 2,Vasopressin V2 receptor, Nanobody 32, ... | | Authors: | Cai, H, Lin, X, Zhao, L, He, M, Yu, J, Zhang, B, Ma, Y, Xie, C, Shui, W, Zhao, Q, Zhu, Y, Wu, B. | | Deposit date: | 2025-05-15 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Noncanonical agonist-dependent and -independent arrestin recruitment of GPR1
Science, 2025
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9UYJ
 | | Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 1 (Conformation 3) | | Descriptor: | Beta-arrestin-1, Chemerin-like receptor 2,Vasopressin V2 receptor, Nanobody 32, ... | | Authors: | Cai, H, Lin, X, Zhao, L, He, M, Yu, J, Zhang, B, Ma, Y, Xie, C, Shui, W, Zhao, Q, Zhu, Y, Wu, B. | | Deposit date: | 2025-05-15 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Noncanonical agonist-dependent and -independent arrestin recruitment of GPR1
Science, 2025
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9UYL
 | | Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 1 (Conformation 4) | | Descriptor: | Beta-arrestin-1, Chemerin-like receptor 2,Vasopressin V2 receptor, Nanobody 32, ... | | Authors: | Cai, H, Lin, X, Zhao, L, He, M, Yu, J, Zhang, B, Ma, Y, Xie, C, Shui, W, Zhao, Q, Zhu, Y, Wu, B. | | Deposit date: | 2025-05-15 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Noncanonical agonist-dependent and -independent arrestin recruitment of GPR1
Science, 2025
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9UYM
 | | Composite map of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 2 | | Descriptor: | Beta-arrestin-2,Beta-arrestin-1, CHOLESTEROL HEMISUCCINATE, Chemerin-like receptor 2,Vasopressin V2 receptor, ... | | Authors: | Cai, H, Lin, X, Zhao, L, He, M, Yu, J, Zhang, B, Ma, Y, Xie, C, Shui, W, Zhao, Q, Zhu, Y, Wu, B. | | Deposit date: | 2025-05-15 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Noncanonical agonist-dependent and -independent arrestin recruitment of GPR1
Science, 2025
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9UYN
 | | Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to beta-arrestin 1 in ligand-free state | | Descriptor: | Beta-arrestin-1, Chemerin-like receptor 2,Vasopressin V2 receptor, Nanobody 32, ... | | Authors: | Cai, H, Lin, X, Zhao, L, He, M, Yu, J, Zhang, B, Ma, Y, Xie, C, Shui, W, Zhao, Q, Zhu, Y, Wu, B. | | Deposit date: | 2025-05-15 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Noncanonical agonist-dependent and -independent arrestin recruitment of GPR1
Science, 2025
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9V69
 | | X-ray crystal structure of the two-electron reduced form of wild type b5R | | Descriptor: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Hirano, Y, Kurihara, K, Kusaka, K, Ostermann, A, Hikita, M, Kimura, S, Miki, K, Tamada, T. | | Deposit date: | 2025-05-27 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (0.96 Å) | | Cite: | Structural basis of hydride and proton transfer reactions revealed by the detection of hydrogen atoms in mammalian NADH-cytochrome b 5 reductase.
Structure, 2025
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9V6A
 | | X-ray crystal structure of the T66V mutant b5R co-crystallized with NADH | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3 | | Authors: | Hirano, Y, Kurihara, K, Kusaka, K, Ostermann, A, Hikita, M, Kimura, S, Miki, K, Tamada, T. | | Deposit date: | 2025-05-27 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (0.94 Å) | | Cite: | Structural basis of hydride and proton transfer reactions revealed by the detection of hydrogen atoms in mammalian NADH-cytochrome b 5 reductase.
Structure, 2025
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9V6B
 | | Neutron crystal structure of the oxidized form of b5R at pD 6.5 | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, NADH-cytochrome b5 reductase 3 | | Authors: | Hirano, Y, Kurihara, K, Kusaka, K, Ostermann, A, Hikita, M, Kimura, S, Miki, K, Tamada, T. | | Deposit date: | 2025-05-27 | | Release date: | 2025-11-19 | | Method: | NEUTRON DIFFRACTION (1.6 Å) | | Cite: | Structural basis of hydride and proton transfer reactions revealed by the detection of hydrogen atoms in mammalian NADH-cytochrome b 5 reductase.
Structure, 2025
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9V6C
 | | Neutron crystal structure of the oxidized form of b5R at pD 7.5 | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, NADH-cytochrome b5 reductase 3 | | Authors: | Hirano, Y, Kurihara, K, Kusaka, K, Ostermann, A, Hikita, M, Kimura, S, Miki, K, Tamada, T. | | Deposit date: | 2025-05-27 | | Release date: | 2025-11-19 | | Method: | NEUTRON DIFFRACTION (1.45 Å) | | Cite: | Structural basis of hydride and proton transfer reactions revealed by the detection of hydrogen atoms in mammalian NADH-cytochrome b 5 reductase.
Structure, 2025
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9V6O
 | | Cryo-EM structure of human kappa opioid receptor - G protein signaling complex bound with nalfurafine. | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | Authors: | Suno-Ikeda, C, Takai, T, Hirose, M, Inoue, A, Sugita, Y, Kato, T, Kobayashi, T, Suno, R. | | Deposit date: | 2025-05-27 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor.
Nat Commun, 16, 2025
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9VCA
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9VFR
 | | Structure of mature Coxsackievirus A6 virion complexed with its receptor KREMEN1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, Kremen protein 1, ... | | Authors: | Ke, X, Li, X, Liu, Z, Liu, K, Yan, X, Shu, B, Zhang, C. | | Deposit date: | 2025-06-11 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (2.55 Å) | | Cite: | Structure of mature Coxsackievirus A6 virion complexed with its receptor KREMEN1
To Be Published
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9VFT
 | | Structure of mature CVA6 virus complexed with 3H7 Fab | | Descriptor: | Genome polyprotein, STEARIC ACID, VH, ... | | Authors: | Ke, X, Li, X, Liu, Z, Liu, K, Yan, X, Shu, B, Zhang, C. | | Deposit date: | 2025-06-11 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (2.59 Å) | | Cite: | Structure of mature CVA6 virus complexed with 3H7 Fab
To Be Published
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9VFU
 | | Structure of mature CVA6 virus complexed with 1F4 Fab | | Descriptor: | Genome polyprotein, STEARIC ACID, VH, ... | | Authors: | Ke, X, Li, X, Liu, Z, Liu, K, Yan, X, Shu, B, Zhang, C. | | Deposit date: | 2025-06-11 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (2.11 Å) | | Cite: | Structure of mature CVA6 virus complexed with 1F4 Fab
To Be Published
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9VG1
 | | Structure of CVA6 empty capsid complexed with 3H7 Fab | | Descriptor: | Genome polyprotein, VH, VL | | Authors: | Ke, X, Li, X, Liu, Z, Liu, K, Yan, X, Shu, B, Zhang, C. | | Deposit date: | 2025-06-12 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structure of CVA6 empty capsid complexed with 3H7 Fab
To Be Published
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9W1N
 | | Human SLC37A4 antiparallel dimer | | Descriptor: | Glucose-6-phosphate exchanger SLC37A4 | | Authors: | Zhou, D, Zhang, Z. | | Deposit date: | 2025-07-26 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis of G6P/Pi transport and inhibition in SLC37A4
Nat.Struct.Mol.Biol., 2025
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9W1O
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9W1P
 | | G6P-bound human SLC37A4 lateral dimer | | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, Glucose-6-phosphate exchanger SLC37A4,Soluble cytochrome b562 | | Authors: | Zhou, D, Zhang, Z. | | Deposit date: | 2025-07-26 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis of G6P/Pi transport and inhibition in SLC37A4
Nat.Struct.Mol.Biol., 2025
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9W1Q
 | | Human SLC37A4 lateral dimer | | Descriptor: | Glucose-6-phosphate exchanger SLC37A4,Soluble cytochrome b562 | | Authors: | Zhou, D, Zhang, Z. | | Deposit date: | 2025-07-26 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis of G6P/Pi transport and inhibition in SLC37A4
Nat.Struct.Mol.Biol., 2025
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9W1R
 | | S-4048-bound human SLC37A4 monomer | | Descriptor: | (1~{S},3~{R},4~{R},5~{R})-1-[[(1~{R},2~{S})-2-(4-chlorophenyl)cyclopropyl]methoxy]-3-[(~{Z})-3-imidazo[4,5-b]pyridin-1-yl-3-phenyl-prop-2-enoyl]oxy-4,5-bis(oxidanyl)cyclohexane-1-carboxylic acid, Glucose-6-phosphate exchanger SLC37A4,Soluble cytochrome b562 | | Authors: | Zhou, D, Zhang, Z. | | Deposit date: | 2025-07-26 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis of G6P/Pi transport and inhibition in SLC37A4
Nat.Struct.Mol.Biol., 2025
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9W49
 | | Cryo-EM structure of human kappa opioid receptor -G protein signaling complex bound with U-50488H | | Descriptor: | 2-(3,4-dichlorophenyl)-~{N}-methyl-~{N}-[(1~{R},2~{R})-2-pyrrolidin-1-ylcyclohexyl]ethanamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Suno-Ikeda, C, Takai, T, Hirose, M, Inoue, A, Sugita, Y, Kato, T, Kobayashi, T, Suno, R. | | Deposit date: | 2025-07-31 | | Release date: | 2025-11-19 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor.
Nat Commun, 16, 2025
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9W4X
 | | N-terminal half domain of EPC3 | | Descriptor: | EPC3 | | Authors: | Xu, Z, Ohki, S. | | Deposit date: | 2025-08-01 | | Release date: | 2025-11-19 | | Method: | SOLUTION NMR | | Cite: | Identification and NMR-based structural characterization of the functional domain of EPC3, a virulence effector of the phytopathogenic fungus Colletotrichum orbiculare.
Front Plant Sci, 16, 2025
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9W7N
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9W7O
 | | Crystal Structure of Taniborbactam in complex with SME-1 class A Carbapenemase | | Descriptor: | (3~{R})-3-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-2-oxidanyl-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid, Beta-lactamase SME-1, TETRAETHYLENE GLYCOL | | Authors: | Dhankhar, K, Hazra, S. | | Deposit date: | 2025-08-06 | | Release date: | 2025-11-19 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Beyond structure and activity: targeting class A carbapenemases with monocyclic and bicyclic boronic acids to counter antimicrobial resistance.
Org.Biomol.Chem., 2025
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