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Yorodumi- PDB-3v4v: crystal structure of a4b7 headpiece complexed with Fab ACT-1 and ... -
+Open data
-Basic information
Entry | Database: PDB / ID: 3v4v | |||||||||
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Title | crystal structure of a4b7 headpiece complexed with Fab ACT-1 and RO0505376 | |||||||||
Components |
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Keywords | CELL ADHESION / MAdCAM-1 / Membrane | |||||||||
Function / homology | Function and homology information clathrin-dependent extracellular exosome endocytosis / immune response in gut-associated lymphoid tissue / negative regulation of protein homodimerization activity / cell-matrix adhesion involved in ameboidal cell migration / integrin alpha4-beta7 complex / diapedesis / integrin alpha4-beta1 complex / cell-cell adhesion mediated by integrin / T cell migration / positive regulation of leukocyte tethering or rolling ...clathrin-dependent extracellular exosome endocytosis / immune response in gut-associated lymphoid tissue / negative regulation of protein homodimerization activity / cell-matrix adhesion involved in ameboidal cell migration / integrin alpha4-beta7 complex / diapedesis / integrin alpha4-beta1 complex / cell-cell adhesion mediated by integrin / T cell migration / positive regulation of leukocyte tethering or rolling / axonogenesis involved in innervation / protein antigen binding / leukocyte tethering or rolling / positive regulation of endothelial cell apoptotic process / RUNX3 Regulates Immune Response and Cell Migration / heterotypic cell-cell adhesion / integrin complex / positive regulation of vascular endothelial cell proliferation / cell adhesion mediated by integrin / neuron projection extension / negative regulation of vasoconstriction / leukocyte cell-cell adhesion / leukocyte migration / receptor clustering / endodermal cell differentiation / cellular response to cytokine stimulus / fibronectin binding / positive regulation of T cell migration / Integrin cell surface interactions / coreceptor activity / cell adhesion molecule binding / substrate adhesion-dependent cell spreading / B cell differentiation / cell-matrix adhesion / integrin-mediated signaling pathway / Cell surface interactions at the vascular wall / cell-cell adhesion / integrin binding / cellular response to amyloid-beta / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / virus receptor activity / growth cone / Potential therapeutics for SARS / receptor complex / cell adhesion / external side of plasma membrane / focal adhesion / neuronal cell body / cell surface / extracellular exosome / membrane / metal ion binding / plasma membrane Similarity search - Function | |||||||||
Biological species | Homo sapiens (human) Mus musculus (house mouse) | |||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.1 Å | |||||||||
Authors | Yu, Y. / Zhu, J. / Springer, T.A. | |||||||||
Citation | Journal: J.Cell Biol. / Year: 2012 Title: Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion Authors: Yu, Y. / Zhu, J. / Mi, L.Z. / Walz, T. / Sun, H. / Chen, J. / Springer, T.A. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 3v4v.cif.gz | 1.1 MB | Display | PDBx/mmCIF format |
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PDB format | pdb3v4v.ent.gz | 934 KB | Display | PDB format |
PDBx/mmJSON format | 3v4v.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 3v4v_validation.pdf.gz | 1.6 MB | Display | wwPDB validaton report |
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Full document | 3v4v_full_validation.pdf.gz | 1.6 MB | Display | |
Data in XML | 3v4v_validation.xml.gz | 97.2 KB | Display | |
Data in CIF | 3v4v_validation.cif.gz | 129.3 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/v4/3v4v ftp://data.pdbj.org/pub/pdb/validation_reports/v4/3v4v | HTTPS FTP |
-Related structure data
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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