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Structure paper

TitleStructural specializations of a4b7, an Integrin that Mediates Rolling Adhesion
Journal, issue, pagesJ. Cell Biol., Vol. 196, Page 131-146, Year 2012
Publish dateDec 15, 2011 (structure data deposition date)
AuthorsYu, Y. / Zhu, J. / Mi, L.Z. / Walz, T. / Sun, H. / Chen, J. / Springer, T.A.
External linksJ. Cell Biol. / PubMed:22232704
MethodsX-ray diffraction
Resolution3.1 - 3.15 Å
Structure data

PDB-3v4p:
crystal structure of a4b7 headpiece complexed with Fab ACT-1
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-3v4v:
crystal structure of a4b7 headpiece complexed with Fab ACT-1 and RO0505376
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-15P:
POLYETHYLENE GLYCOL (N=34) / precipitant*YM

ChemComp-MG:
Unknown entry

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-0DU:
N-(2,6-dichlorobenzoyl)-4-[1,6-dimethyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]-L-phenylalanine

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsCELL ADHESION / MAdCAM-1 / Membrane

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