Defective CHST6 causes MCDC1 / Defective ST3GAL3 causes MCT12 and EIEE15 / keratan sulfate catabolic process / keratan sulfate biosynthetic process / Keratan sulfate degradation / Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) / Keratan sulfate biosynthesis / chondrocyte development / proteoglycan biosynthetic process / hyaluronic acid binding ...Defective CHST6 causes MCDC1 / Defective ST3GAL3 causes MCT12 and EIEE15 / keratan sulfate catabolic process / keratan sulfate biosynthetic process / Keratan sulfate degradation / Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) / Keratan sulfate biosynthesis / chondrocyte development / proteoglycan biosynthetic process / hyaluronic acid binding / regulation of interleukin-4 production / regulation of interleukin-10 production / positive regulation of T cell mediated immune response to tumor cell / myeloid dendritic cell antigen processing and presentation / antigen processing and presentation of endogenous peptide antigen via MHC class II / autolysosome membrane / regulation of T-helper cell differentiation / positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation / MHC class II receptor activity / positive regulation of CD4-positive, alpha-beta T cell activation / antigen processing and presentation of peptide or polysaccharide antigen via MHC class II / positive regulation of memory T cell differentiation / positive regulation of monocyte differentiation / CD4 receptor binding / positive regulation of kinase activity / inflammatory response to antigenic stimulus / collagen fibril organization / 中間径フィラメント / transport vesicle membrane / extracellular matrix structural constituent / T-helper 1 type immune response / polysaccharide binding / cartilage condensation / Translocation of ZAP-70 to Immunological synapse / Phosphorylation of CD3 and TCR zeta chains / positive regulation of insulin secretion involved in cellular response to glucose stimulus / 液性免疫 / macrophage differentiation / negative regulation of type II interferon production / Generation of second messenger molecules / 免疫シナプス / 基底膜 / ECM proteoglycans / PD-1 signaling / epidermis development / negative regulation of inflammatory response to antigenic stimulus / negative regulation of T cell proliferation / MHC class II antigen presentation / detection of bacterium / Degradation of the extracellular matrix / extracellular matrix organization / T cell receptor binding / lysosomal lumen / 細胞外マトリックス / trans-Golgi network membrane / central nervous system development / skeletal system development / lumenal side of endoplasmic reticulum membrane / protein tetramerization / clathrin-coated endocytic vesicle membrane / ER to Golgi transport vesicle membrane / structural constituent of cytoskeleton / 認識 / positive regulation of T cell mediated cytotoxicity / peptide antigen assembly with MHC class II protein complex / Golgi lumen / MHC class II protein complex / peptide antigen binding / endocytic vesicle membrane / antigen processing and presentation of exogenous peptide antigen via MHC class II / positive regulation of immune response / Interferon gamma signaling / positive regulation of T cell activation / Downstream TCR signaling / MHC class II protein complex binding / late endosome membrane / heart development / T cell receptor signaling pathway / early endosome membrane / carbohydrate binding / collagen-containing extracellular matrix / positive regulation of canonical NF-kappaB signal transduction / positive regulation of MAPK cascade / 獲得免疫系 / positive regulation of viral entry into host cell / リソソーム / positive regulation of ERK1 and ERK2 cascade / 細胞接着 / 免疫応答 / positive regulation of protein phosphorylation / lysosomal membrane / external side of plasma membrane / ゴルジ体 / positive regulation of DNA-templated transcription / 細胞膜 / シグナル伝達 / タンパク質分解 / extracellular space / extracellular exosome / extracellular region 類似検索 - 分子機能
Aggrecan/versican, C-type lectin-like domain / Link domain / Extracellular link domain / Link domain signature. / Link domain profile. / Link (Hyaluronan-binding) / Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 / Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 / MHC class II, beta chain, N-terminal / Class II histocompatibility antigen, beta domain ...Aggrecan/versican, C-type lectin-like domain / Link domain / Extracellular link domain / Link domain signature. / Link domain profile. / Link (Hyaluronan-binding) / Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 / Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 / MHC class II, beta chain, N-terminal / Class II histocompatibility antigen, beta domain / Class II histocompatibility antigen, beta domain / MHC class II, alpha chain, N-terminal / Class II histocompatibility antigen, alpha domain / Class II histocompatibility antigen, alpha domain / MHC class II, alpha/beta chain, N-terminal / C-type lectin, conserved site / C-type lectin domain signature. / Sushi repeat (SCR repeat) / Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR) / Sushi/SCR/CCP domain / Sushi/CCP/SCR domain profile. / Sushi/SCR/CCP superfamily / Lectin C-type domain / C-type lectin domain profile. / C-type lectin-like / C-type lectin (CTL) or carbohydrate-recognition domain (CRD) / C-type lectin-like/link domain superfamily / C-type lectin fold / Epidermal growth factor-like domain. / EGF-like domain profile. / EGF-like domain signature 2. / EGF-like domain signature 1. / EGF様ドメイン / Immunoglobulin V-Type / Immunoglobulin V-set domain / MHC classes I/II-like antigen recognition protein / Immunoglobulin V-set domain / Immunoglobulin/major histocompatibility complex, conserved site / Immunoglobulin subtype / Immunoglobulins and major histocompatibility complex proteins signature. / 抗体 / Immunoglobulin C-Type / Immunoglobulin C1-set / Immunoglobulin C1-set domain / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / 抗体 / Roll / Immunoglobulin-like fold / Immunoglobulin-like / サンドイッチ / Mainly Beta / Alpha Beta 類似検索 - ドメイン・相同性
HLA class II histocompatibility antigen, DR alpha chain / HLA class II histocompatibility antigen, DRB1 beta chain / HLA class II histocompatibility antigen, DRB1 beta chain / Aggrecan core protein 類似検索 - 構成要素
A: HLA class II histocompatibility antigen, DR alpha chain B: HLA class II histocompatibility antigen, DRB1-4 beta chain C: Aggrecan core protein ヘテロ分子
Aggrecancoreprotein / Cartilage-specific proteoglycan core protein / CSPCP / Chondroitin sulfate proteoglycan core ...Cartilage-specific proteoglycan core protein / CSPCP / Chondroitin sulfate proteoglycan core protein 1 / Chondroitin sulfate proteoglycan 1 / Aggrecan core protein 2
分子量: 1802.916 Da / 分子数: 1 / 断片: UNP residues 89-103 / 由来タイプ: 合成 詳細: This sequence is from human aggrecan and contains citrulline at positions 93 and 95 由来: (合成) Homo sapiens (ヒト) / 参照: UniProt: P16112