- PDB-3kko: Crystal structure of M-Ras P40D/D41E/L51R in complex with GppNHp -
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基本情報
登録情報
データベース: PDB / ID: 3kko
タイトル
Crystal structure of M-Ras P40D/D41E/L51R in complex with GppNHp
要素
Ras-related protein M-Ras
キーワード
SIGNALING PROTEIN / GTP-binding / GTPase (GTPアーゼ)
機能・相同性
機能・相同性情報
RAF activation / GTP-dependent protein binding / cellular response to leukemia inhibitory factor / 低分子量GTPアーゼ / G protein activity / GDP binding / Ras protein signal transduction / GTPase activity / GTP binding / 細胞膜 類似検索 - 分子機能
Small GTPase, Ras-type / small GTPase Ras family profile. / Ran (Ras-related nuclear proteins) /TC4 subfamily of small GTPases / Rho (Ras homology) subfamily of Ras-like small GTPases / Ras subfamily of RAS small GTPases / 低分子量GTPアーゼ / 低分子量GTPアーゼ / Rab subfamily of small GTPases / Small GTP-binding protein domain / P-loop containing nucleotide triphosphate hydrolases ...Small GTPase, Ras-type / small GTPase Ras family profile. / Ran (Ras-related nuclear proteins) /TC4 subfamily of small GTPases / Rho (Ras homology) subfamily of Ras-like small GTPases / Ras subfamily of RAS small GTPases / 低分子量GTPアーゼ / 低分子量GTPアーゼ / Rab subfamily of small GTPases / Small GTP-binding protein domain / P-loop containing nucleotide triphosphate hydrolases / P-loop containing nucleoside triphosphate hydrolase / ロスマンフォールド / 3-Layer(aba) Sandwich / Alpha Beta 類似検索 - ドメイン・相同性
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / Ras-related protein M-Ras 類似検索 - 構成要素
解像度: 1.9→49.57 Å / Cor.coef. Fo:Fc: 0.955 / Cor.coef. Fo:Fc free: 0.935 / SU B: 2.937 / SU ML: 0.087 / 交差検証法: THROUGHOUT / ESU R: 0.143 / ESU R Free: 0.134 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD / 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
Rfactor
反射数
%反射
Selection details
Rfree
0.22192
2649
5.1 %
RANDOM
Rwork
0.18392
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all
0.18584
49403
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obs
0.18584
49403
99.18 %
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溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: MASK