登録情報 | データベース: PDB / ID: 8t32 |
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タイトル | Crystal structure of K48 acetylated GABARAP in complex with the LIR of TP53INP2/DOR |
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要素 | - Gamma-aminobutyric acid receptor-associated protein
- LIR of DOR
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キーワード | PROTEIN BINDING / Autophagy / GABARAP acetylation / DOR LIR / TP53INP2 LIR |
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機能・相同性 | 機能・相同性情報
positive regulation of protein K48-linked ubiquitination / regulation of Rac protein signal transduction / GABA receptor binding / phosphatidylethanolamine binding / cellular response to nitrogen starvation / TBC/RABGAPs / microtubule associated complex / Macroautophagy / beta-tubulin binding / axoneme ...positive regulation of protein K48-linked ubiquitination / regulation of Rac protein signal transduction / GABA receptor binding / phosphatidylethanolamine binding / cellular response to nitrogen starvation / TBC/RABGAPs / microtubule associated complex / Macroautophagy / beta-tubulin binding / axoneme / autophagosome membrane / autophagosome maturation / extrinsic apoptotic signaling pathway via death domain receptors / autophagosome assembly / autophagosome / smooth endoplasmic reticulum / protein targeting / sperm midpiece / microtubule cytoskeleton organization / actin cytoskeleton / positive regulation of proteasomal ubiquitin-dependent protein catabolic process / protein transport / cytoplasmic vesicle / microtubule binding / chemical synaptic transmission / microtubule / lysosome / Golgi membrane / ubiquitin protein ligase binding / synapse / plasma membrane / cytosol類似検索 - 分子機能 Autophagy protein Atg8 ubiquitin-like / Autophagy protein Atg8 ubiquitin like / Ubiquitin-like domain superfamily類似検索 - ドメイン・相同性 TRIETHYLENE GLYCOL / Gamma-aminobutyric acid receptor-associated protein類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.051 Å |
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データ登録者 | Ali, M.G.H. / Wahba, H.M. / Cyr, N. / Omichinski, J.G. |
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資金援助 | カナダ, 1件 組織 | 認可番号 | 国 |
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Canadian Institutes of Health Research (CIHR) | | カナダ |
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引用 | ジャーナル: Autophagy / 年: 2024 タイトル: Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. 著者: Ali, M.G. / Wahba, H.M. / Igelmann, S. / Cyr, N. / Ferbeyre, G. / Omichinski, J.G. |
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履歴 | 登録 | 2023年6月7日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2024年5月22日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2024年6月5日 | Group: Database references / カテゴリ: citation / Item: _citation.page_first / _citation.page_last |
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