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Yorodumi- PDB-7m3i: Structure of SARS-CoV-2 spike protein receptor binding domain in ... -
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-Basic information
Entry | Database: PDB / ID: 7m3i | ||||||
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Title | Structure of SARS-CoV-2 spike protein receptor binding domain in complex with a neutralizing antibody, CV2-75 Fab | ||||||
Components |
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Keywords | IMMUNE SYSTEM/VIRAL PROTEIN / SARS-CoV-2 / COVID-19 / Antibody / IMMUNE SYSTEM / IMMUNE SYSTEM-VIRAL PROTEIN complex | ||||||
Function / homology | Function and homology information Maturation of spike protein / viral translation / Translation of Structural Proteins / Virion Assembly and Release / host cell surface / host extracellular space / suppression by virus of host tetherin activity / Induction of Cell-Cell Fusion / structural constituent of virion / entry receptor-mediated virion attachment to host cell ...Maturation of spike protein / viral translation / Translation of Structural Proteins / Virion Assembly and Release / host cell surface / host extracellular space / suppression by virus of host tetherin activity / Induction of Cell-Cell Fusion / structural constituent of virion / entry receptor-mediated virion attachment to host cell / host cell endoplasmic reticulum-Golgi intermediate compartment membrane / receptor-mediated endocytosis of virus by host cell / Attachment and Entry / membrane fusion / positive regulation of viral entry into host cell / receptor-mediated virion attachment to host cell / receptor ligand activity / symbiont-mediated suppression of host innate immune response / host cell surface receptor binding / fusion of virus membrane with host plasma membrane / fusion of virus membrane with host endosome membrane / viral envelope / virion attachment to host cell / SARS-CoV-2 activates/modulates innate and adaptive immune responses / host cell plasma membrane / virion membrane / identical protein binding / membrane / plasma membrane Similarity search - Function | ||||||
Biological species | Homo sapiens (human) Severe acute respiratory syndrome coronavirus 2 | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.8 Å | ||||||
Authors | Hurlburt, N.K. / Pancera, M. | ||||||
Citation | Journal: Cell Rep / Year: 2021 Title: Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects. Authors: Jennewein, M.F. / MacCamy, A.J. / Akins, N.R. / Feng, J. / Homad, L.J. / Hurlburt, N.K. / Seydoux, E. / Wan, Y.H. / Stuart, A.B. / Edara, V.V. / Floyd, K. / Vanderheiden, A. / Mascola, J.R. ...Authors: Jennewein, M.F. / MacCamy, A.J. / Akins, N.R. / Feng, J. / Homad, L.J. / Hurlburt, N.K. / Seydoux, E. / Wan, Y.H. / Stuart, A.B. / Edara, V.V. / Floyd, K. / Vanderheiden, A. / Mascola, J.R. / Doria-Rose, N. / Wang, L. / Yang, E.S. / Chu, H.Y. / Torres, J.L. / Ozorowski, G. / Ward, A.B. / Whaley, R.E. / Cohen, K.W. / Pancera, M. / McElrath, M.J. / Englund, J.A. / Finzi, A. / Suthar, M.S. / McGuire, A.T. / Stamatatos, L. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7m3i.cif.gz | 476.5 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7m3i.ent.gz | 393.8 KB | Display | PDB format |
PDBx/mmJSON format | 7m3i.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7m3i_validation.pdf.gz | 507.8 KB | Display | wwPDB validaton report |
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Full document | 7m3i_full_validation.pdf.gz | 525.7 KB | Display | |
Data in XML | 7m3i_validation.xml.gz | 44.8 KB | Display | |
Data in CIF | 7m3i_validation.cif.gz | 60.7 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/m3/7m3i ftp://data.pdbj.org/pub/pdb/validation_reports/m3/7m3i | HTTPS FTP |
-Related structure data
-Links
-Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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