- PDB-7lir: Structure of the invertebrate ALK GRD -
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IDまたはキーワード:
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基本情報
登録情報
データベース: PDB / ID: 7lir
タイトル
Structure of the invertebrate ALK GRD
要素
ALK tyrosine kinase receptor homolog scd-2
キーワード
SIGNALING PROTEIN / ALK / anaplastic lymphoma kinase / GRD / glycine rich domain / Pole / poly-glycine extension / PXL / poly-glycine extension loops / neuroblastoma / cancer / receptor / kinase / oncogene / AUG / augmentor / ALKAL / ALK and LTK activating ligand / FAM150
機能・相同性
機能・相同性情報
dauer larval development / sensory processing / sensory perception of chemical stimulus / regulation of neuron differentiation / transmembrane receptor protein tyrosine kinase activity / receptor protein-tyrosine kinase / chemotaxis / membrane => GO:0016020 / ATP binding / plasma membrane 類似検索 - 分子機能
MAM domain / MAM domain profile. / LDL-receptor class A (LDLRA) domain profile. / Low-density lipoprotein receptor domain class A / Low-density lipoprotein (LDL) receptor class A repeat / Tyrosine-protein kinase, catalytic domain / Tyrosine kinase, catalytic domain / Tyrosine protein kinases specific active-site signature. / Concanavalin A-like lectin/glucanase domain superfamily / Tyrosine-protein kinase, active site ...MAM domain / MAM domain profile. / LDL-receptor class A (LDLRA) domain profile. / Low-density lipoprotein receptor domain class A / Low-density lipoprotein (LDL) receptor class A repeat / Tyrosine-protein kinase, catalytic domain / Tyrosine kinase, catalytic domain / Tyrosine protein kinases specific active-site signature. / Concanavalin A-like lectin/glucanase domain superfamily / Tyrosine-protein kinase, active site / Protein tyrosine and serine/threonine kinase / Serine-threonine/tyrosine-protein kinase, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily 類似検索 - ドメイン・相同性
構造決定の手法: 単波長異常分散 / 解像度: 2.6→50.18 Å / Cor.coef. Fo:Fc: 0.938 / Cor.coef. Fo:Fc free: 0.908 / SU B: 12.656 / SU ML: 0.247 / SU R Cruickshank DPI: 0.313 / 交差検証法: THROUGHOUT / σ(F): 0 / ESU R: 0.313 / ESU R Free: 0.26 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY
Rfactor
反射数
%反射
Selection details
Rfree
0.2701
2175
4.8 %
RANDOM
Rwork
0.2233
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obs
0.2255
42770
99.99 %
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溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: MASK