+Open data
-Basic information
Entry | Database: PDB / ID: 7k3d | ||||||||||||
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Title | The structure of NTMT1 in complex with compound DC1-13 | ||||||||||||
Components | N-terminal Xaa-Pro-Lys N-methyltransferase 1 | ||||||||||||
Keywords | transferase/transferase inhibitor / methyltransferase / enzyme / inhibitor complex / TRANSFERASE / transferase-transferase inhibitor complex | ||||||||||||
Function / homology | Function and homology information N-terminal peptidyl-glycine methylation / N-terminal peptidyl-serine dimethylation / N-terminal peptidyl-serine trimethylation / protein N-terminal methyltransferase / N-terminal peptidyl-proline dimethylation / N-terminal protein N-methyltransferase activity / protein methyltransferase activity / spindle organization / histone methyltransferase activity / chromosome segregation ...N-terminal peptidyl-glycine methylation / N-terminal peptidyl-serine dimethylation / N-terminal peptidyl-serine trimethylation / protein N-terminal methyltransferase / N-terminal peptidyl-proline dimethylation / N-terminal protein N-methyltransferase activity / protein methyltransferase activity / spindle organization / histone methyltransferase activity / chromosome segregation / nucleoplasm / nucleus / cytoplasm / cytosol Similarity search - Function | ||||||||||||
Biological species | Homo sapiens (human) | ||||||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.34 Å | ||||||||||||
Authors | Chen, D. / Huang, R. / Noinaj, N. | ||||||||||||
Funding support | United States, 3items
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Citation | Journal: Acs Med.Chem.Lett. / Year: 2021 Title: Structure-based Discovery of Cell-Potent Peptidomimetic Inhibitors for Protein N-Terminal Methyltransferase 1. Authors: Chen, D. / Dong, G. / Deng, Y. / Noinaj, N. / Huang, R. | ||||||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7k3d.cif.gz | 113.3 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7k3d.ent.gz | 83.4 KB | Display | PDB format |
PDBx/mmJSON format | 7k3d.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7k3d_validation.pdf.gz | 1.4 MB | Display | wwPDB validaton report |
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Full document | 7k3d_full_validation.pdf.gz | 1.5 MB | Display | |
Data in XML | 7k3d_validation.xml.gz | 22 KB | Display | |
Data in CIF | 7k3d_validation.cif.gz | 30.2 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/k3/7k3d ftp://data.pdbj.org/pub/pdb/validation_reports/k3/7k3d | HTTPS FTP |
-Related structure data
Related structure data | 6dtnS S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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