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Open data
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Basic information
Entry | Database: PDB / ID: 7gss | ||||||
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Title | Human glutathione S-transferase P1-1, complex with glutathione | ||||||
![]() | GLUTATHIONE S-TRANSFERASE P1-1 | ||||||
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Function / homology | ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() | ||||||
![]() | Oakley, A. / Parker, M. | ||||||
![]() | ![]() Title: The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution. Authors: Oakley, A.J. / Bello, M.L. / Battistoni, A. / Ricci, G. / Rossjohn, J. / Villar, H.O. / Parker, M.W. #1: ![]() Title: Three-Dimensional Structure of Class Pi Glutathione S-Transferase from Human Placenta in Complex with S-Hexylglutathione at 2.8 A Resolution Authors: Reinemer, P. / Dirr, H.W. / Ladenstein, R. / Huber, R. / Lo Bello, M. / Federici, G. / Parker, M.W. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 97.3 KB | Display | ![]() |
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PDB format | ![]() | 75.5 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Related structure data | ![]() 10gsC ![]() 5gssC ![]() 6gssC ![]() 8gssC ![]() 9gssC ![]() 1gssS S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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1 |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS oper: (Code: given Matrix: (-0.99987, -0.015867, -0.002893), Vector ![]() |
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Components
#1: Protein | Mass: 23246.570 Da / Num. of mol.: 2 / Fragment: TWO INTACT MONOMERS Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() #2: Chemical | ![]() #3: Chemical | ![]() #4: Water | ChemComp-HOH / | ![]() |
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-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.61 Å3/Da / Density % sol: 52.91 % | ||||||||||||||||||||||||||||||||||||||||
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Crystal grow![]() | pH: 6.2 / Details: pH 6.2 | ||||||||||||||||||||||||||||||||||||||||
Crystal grow | *PLUS Temperature: 22 ℃ / pH: 7 / Method: vapor diffusion, hanging drop | ||||||||||||||||||||||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() |
Detector | Type: MARRESEARCH / Detector: IMAGE PLATE / Date: Oct 28, 1995 |
Radiation | Monochromator: GRAPHITE(002) / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength![]() |
Reflection | Resolution: 2.2→40 Å / Num. obs: 21054 / % possible obs: 83 % / Observed criterion σ(I): -3 / Redundancy: 3.7 % / Rsym value: 0.133 / Net I/σ(I): 9.4 |
Reflection shell | Resolution: 2.2→2.25 Å / Mean I/σ(I) obs: 3.3 / Rsym value: 0.382 / % possible all: 86 |
Reflection | *PLUS % possible obs: 83 % / Num. measured all: 79057 / Rmerge(I) obs: 0.133 |
Reflection shell | *PLUS % possible obs: 86 % / Rmerge(I) obs: 0.382 |
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Processing
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Refinement | Method to determine structure![]() ![]() Starting model: PDB ENTRY 1GSS Resolution: 2.2→15 Å / Isotropic thermal model: RESTRAINED / Cross valid method: THROUGHOUT / σ(F): 0
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Refinement step | Cycle: LAST / Resolution: 2.2→15 Å
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Refine LS restraints |
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LS refinement shell | Resolution: 2.2→2.3 Å / Total num. of bins used: 8
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Xplor file |
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Software | *PLUS Name: ![]() | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints | *PLUS
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