+Open data
-Basic information
Entry | Database: PDB / ID: 7fj2 | ||||||
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Title | Structure of FOXM1 homodimer bound to a palindromic DNA site | ||||||
Components |
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Keywords | TRANSCRIPTION / Forkhead transcription factors / FOXM1 / Dimer / DNA binding | ||||||
Function / homology | Function and homology information regulation of Ras protein signal transduction / Polo-like kinase mediated events / regulation of reactive oxygen species metabolic process / positive regulation of double-strand break repair / negative regulation of stress-activated MAPK cascade / DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator / Cyclin A/B1/B2 associated events during G2/M transition / regulation of cell growth / RNA polymerase II transcription regulatory region sequence-specific DNA binding / G2/M transition of mitotic cell cycle ...regulation of Ras protein signal transduction / Polo-like kinase mediated events / regulation of reactive oxygen species metabolic process / positive regulation of double-strand break repair / negative regulation of stress-activated MAPK cascade / DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator / Cyclin A/B1/B2 associated events during G2/M transition / regulation of cell growth / RNA polymerase II transcription regulatory region sequence-specific DNA binding / G2/M transition of mitotic cell cycle / regulation of cell population proliferation / DNA-binding transcription factor activity, RNA polymerase II-specific / regulation of cell cycle / DNA-binding transcription factor activity / DNA repair / negative regulation of DNA-templated transcription / positive regulation of cell population proliferation / chromatin / regulation of transcription by RNA polymerase II / protein kinase binding / positive regulation of DNA-templated transcription / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / DNA binding / nucleoplasm / nucleus Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / Resolution: 3.098 Å | ||||||
Authors | Dai, S.Y. / Li, J. / Zhang, H.J. | ||||||
Funding support | China, 1items
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Citation | Journal: J.Mol.Biol. / Year: 2021 Title: Mechanistic Insights into the Preference for Tandem Binding Sites in DNA Recognition by FOXM1. Authors: Zhang, H. / Dai, S. / Liang, X. / Li, J. / Chen, Y. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7fj2.cif.gz | 231.6 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7fj2.ent.gz | 180.5 KB | Display | PDB format |
PDBx/mmJSON format | 7fj2.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7fj2_validation.pdf.gz | 457.3 KB | Display | wwPDB validaton report |
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Full document | 7fj2_full_validation.pdf.gz | 458.3 KB | Display | |
Data in XML | 7fj2_validation.xml.gz | 13.8 KB | Display | |
Data in CIF | 7fj2_validation.cif.gz | 19.2 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/fj/7fj2 ftp://data.pdbj.org/pub/pdb/validation_reports/fj/7fj2 | HTTPS FTP |
-Related structure data
Related structure data | 3g73S S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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