登録情報 データベース : PDB / ID : 6zbk 構造の表示 ダウンロードとリンクタイトル Crystal structure of the human complex between RPAP3 and TRBP 要素RISC-loading complex subunit TARBP2 RNA polymerase II-associated protein 3 詳細キーワード RNA BINDING PROTEIN / RNPs / MicroRNAs / RNA Induced Silencing Complex / dsRNA pathways機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
regulation of siRNA processing / regulation of miRNA processing / regulation of viral transcription / negative regulation of cytoplasmic pattern recognition receptor signaling pathway / regulation of regulatory ncRNA processing / negative regulation of defense response to virus by host / pre-miRNA binding / Small interfering RNA (siRNA) biogenesis / global gene silencing by mRNA cleavage / R2TP complex ... regulation of siRNA processing / regulation of miRNA processing / regulation of viral transcription / negative regulation of cytoplasmic pattern recognition receptor signaling pathway / regulation of regulatory ncRNA processing / negative regulation of defense response to virus by host / pre-miRNA binding / Small interfering RNA (siRNA) biogenesis / global gene silencing by mRNA cleavage / R2TP complex / RPAP3/R2TP/prefoldin-like complex / RISC-loading complex / RISC complex assembly / miRNA processing / siRNA binding / pre-miRNA processing / pre-mRNA binding / siRNA processing / protein folding chaperone complex / RISC complex / MicroRNA (miRNA) biogenesis / miRNA binding / positive regulation of viral genome replication / protein sequestering activity / negative regulation of protein kinase activity / PKR-mediated signaling / double-stranded RNA binding / regulation of translation / nuclear body / protein stabilization / perinuclear region of cytoplasm / enzyme binding / protein homodimerization activity / nucleoplasm / identical protein binding / nucleus / cytoplasm / cytosol 類似検索 - 分子機能 RISC-loading complex subunit TRBP2 / TRBP2 , first double-stranded RNA binding domain / TRBP2 , second double-stranded RNA binding domain / TRBP2 , third double-stranded RNA binding domain / RNA-polymerase II-associated protein 3-like, C-terminal domain / Potential Monad-binding region of RPAP3 / Double-stranded RNA binding motif / Double-stranded RNA binding motif / Tetratricopeptide repeat / Tetratricopeptide repeat 1 ... RISC-loading complex subunit TRBP2 / TRBP2 , first double-stranded RNA binding domain / TRBP2 , second double-stranded RNA binding domain / TRBP2 , third double-stranded RNA binding domain / RNA-polymerase II-associated protein 3-like, C-terminal domain / Potential Monad-binding region of RPAP3 / Double-stranded RNA binding motif / Double-stranded RNA binding motif / Tetratricopeptide repeat / Tetratricopeptide repeat 1 / Tetratricopeptide repeat / Tetratricopeptide repeat / Double stranded RNA-binding domain (dsRBD) profile. / Double-stranded RNA-binding domain / TPR repeat region circular profile. / TPR repeat profile. / Tetratricopeptide repeats / Tetratricopeptide repeat / Tetratricopeptide-like helical domain superfamily 類似検索 - ドメイン・相同性 RISC-loading complex subunit TARBP2 / RNA polymerase II-associated protein 3 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.49 Å 詳細データ登録者 Charron, C. / Abel, Y. / Charpentier, B. / Rederstorff, M. 引用ジャーナル : Nucleic Acids Res. / 年 : 2022タイトル : The interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity.著者 : Abel, Y. / Charron, C. / Virciglio, C. / Bourguignon-Igel, V. / Quinternet, M. / Chagot, M.E. / Robert, M.C. / Verheggen, C. / Branlant, C. / Bertrand, E. / Manival, X. / Charpentier, B. / Rederstorff, M. 履歴 登録 2020年6月8日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2021年6月30日 Provider : repository / タイプ : Initial release改定 1.1 2022年3月9日 Group : Database references / Structure summaryカテゴリ : citation / citation_author ... citation / citation_author / database_2 / struct Item : _citation.country / _citation.journal_abbrev ... _citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct.title 改定 1.2 2024年1月24日 Group : Data collection / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model
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