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- PDB-6weo: IL-22 Signaling Complex with IL-22R1 and IL-10Rbeta -

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Basic information

Entry
Database: PDB / ID: 6weo
TitleIL-22 Signaling Complex with IL-22R1 and IL-10Rbeta
Components
  • Interleukin-10 receptor subunit beta
  • Interleukin-22
  • Interleukin-22 receptor subunit alpha-1
KeywordsCYTOKINE / Interleukin / Receptor / Signaling
Function / homology
Function and homology information


interleukin-20 binding / interleukin-22 receptor activity / regulation of tyrosine phosphorylation of STAT protein / Interleukin-10 signaling / interleukin-10 receptor activity / Interleukin-20 family signaling / cytokine receptor activity / reactive oxygen species metabolic process / cytokine activity / negative regulation of inflammatory response ...interleukin-20 binding / interleukin-22 receptor activity / regulation of tyrosine phosphorylation of STAT protein / Interleukin-10 signaling / interleukin-10 receptor activity / Interleukin-20 family signaling / cytokine receptor activity / reactive oxygen species metabolic process / cytokine activity / negative regulation of inflammatory response / cytokine-mediated signaling pathway / defense response to Gram-negative bacterium / defense response to virus / positive regulation of transcription by RNA polymerase II / extracellular space / plasma membrane
Similarity search - Function
Interleukin-22 / Interleukin 22 IL-10-related T-cell-derived-inducible factor / Interleukin-10, conserved site / Interleukin-10 family signature. / Interferon/interleukin receptor domain / Interferon-alpha/beta receptor, fibronectin type III / : / Tissue factor / Four-helical cytokine-like, core / Fibronectin type 3 domain ...Interleukin-22 / Interleukin 22 IL-10-related T-cell-derived-inducible factor / Interleukin-10, conserved site / Interleukin-10 family signature. / Interferon/interleukin receptor domain / Interferon-alpha/beta receptor, fibronectin type III / : / Tissue factor / Four-helical cytokine-like, core / Fibronectin type 3 domain / Fibronectin type-III domain profile. / Fibronectin type III / Fibronectin type III superfamily / Immunoglobulin-like fold
Similarity search - Domain/homology
Interleukin-10 receptor subunit beta / Interleukin-22 receptor subunit alpha-1 / Interleukin-22
Similarity search - Component
Biological speciesMus musculus (house mouse)
MethodX-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.6 Å
AuthorsSaxton, R.A. / Jude, K.M. / Henneberg, L.T. / Garcia, K.C.
Funding support United States, 1items
OrganizationGrant numberCountry
National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)R37-AI51321 United States
CitationJournal: Immunity / Year: 2021
Title: The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design.
Authors: Saxton, R.A. / Henneberg, L.T. / Calafiore, M. / Su, L. / Jude, K.M. / Hanash, A.M. / Garcia, K.C.
History
DepositionApr 2, 2020Deposition site: RCSB / Processing site: RCSB
Revision 1.0Apr 28, 2021Provider: repository / Type: Initial release
Revision 1.1Oct 18, 2023Group: Data collection / Database references / Refinement description
Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model
Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession
Revision 1.2Oct 23, 2024Group: Structure summary / Category: pdbx_entry_details / pdbx_modification_feature / Item: _pdbx_entry_details.has_protein_modification

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Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

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Assembly

Deposited unit
0: Interleukin-10 receptor subunit beta
1: Interleukin-22 receptor subunit alpha-1
2: Interleukin-22
3: Interleukin-10 receptor subunit beta
4: Interleukin-22 receptor subunit alpha-1
5: Interleukin-22
6: Interleukin-10 receptor subunit beta
7: Interleukin-22 receptor subunit alpha-1
8: Interleukin-22
9: Interleukin-10 receptor subunit beta
A: Interleukin-22 receptor subunit alpha-1
B: Interleukin-22 receptor subunit alpha-1
C: Interleukin-10 receptor subunit beta
D: Interleukin-22
E: Interleukin-10 receptor subunit beta
F: Interleukin-22 receptor subunit alpha-1
G: Interleukin-22
H: Interleukin-10 receptor subunit beta
I: Interleukin-22 receptor subunit alpha-1
J: Interleukin-22
K: Interleukin-10 receptor subunit beta
L: Interleukin-22
M: Interleukin-22 receptor subunit alpha-1
N: Interleukin-22
O: Interleukin-10 receptor subunit beta
P: Interleukin-22 receptor subunit alpha-1
Q: Interleukin-22
R: Interleukin-10 receptor subunit beta
S: Interleukin-22 receptor subunit alpha-1
T: Interleukin-22
U: Interleukin-10 receptor subunit beta
V: Interleukin-22 receptor subunit alpha-1
W: Interleukin-22
X: Interleukin-10 receptor subunit beta
Y: Interleukin-22 receptor subunit alpha-1
Z: Interleukin-22
hetero molecules


Theoretical massNumber of molelcules
Total (without water)781,89867
Polymers768,62036
Non-polymers13,27931
Water6,125340
1
0: Interleukin-10 receptor subunit beta
Y: Interleukin-22 receptor subunit alpha-1
Z: Interleukin-22
hetero molecules


Theoretical massNumber of molelcules
Total (without water)65,0256
Polymers64,0523
Non-polymers9733
Water362
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
2
1: Interleukin-22 receptor subunit alpha-1
2: Interleukin-22
3: Interleukin-10 receptor subunit beta
hetero molecules


Theoretical massNumber of molelcules
Total (without water)65,3555
Polymers64,0523
Non-polymers1,3032
Water543
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
3
4: Interleukin-22 receptor subunit alpha-1
5: Interleukin-22
6: Interleukin-10 receptor subunit beta
hetero molecules


Theoretical massNumber of molelcules
Total (without water)65,1525
Polymers64,0523
Non-polymers1,1002
Water543
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
4
7: Interleukin-22 receptor subunit alpha-1
8: Interleukin-22
9: Interleukin-10 receptor subunit beta
hetero molecules


Theoretical massNumber of molelcules
Total (without water)64,9905
Polymers64,0523
Non-polymers9382
Water543
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
5
A: Interleukin-22 receptor subunit alpha-1
C: Interleukin-10 receptor subunit beta
L: Interleukin-22
hetero molecules


Theoretical massNumber of molelcules
Total (without water)65,3016
Polymers64,0523
Non-polymers1,2493
Water543
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
6
B: Interleukin-22 receptor subunit alpha-1
D: Interleukin-22
E: Interleukin-10 receptor subunit beta
hetero molecules


Theoretical massNumber of molelcules
Total (without water)65,1525
Polymers64,0523
Non-polymers1,1002
Water543
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
7
F: Interleukin-22 receptor subunit alpha-1
G: Interleukin-22
H: Interleukin-10 receptor subunit beta
hetero molecules


Theoretical massNumber of molelcules
Total (without water)65,2856
Polymers64,0523
Non-polymers1,2333
Water543
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
8
I: Interleukin-22 receptor subunit alpha-1
J: Interleukin-22
K: Interleukin-10 receptor subunit beta
hetero molecules


Theoretical massNumber of molelcules
Total (without water)65,6857
Polymers64,0523
Non-polymers1,6344
Water543
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
9
M: Interleukin-22 receptor subunit alpha-1
N: Interleukin-22
O: Interleukin-10 receptor subunit beta
hetero molecules


Theoretical massNumber of molelcules
Total (without water)65,3367
Polymers64,0523
Non-polymers1,2844
Water543
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
10
P: Interleukin-22 receptor subunit alpha-1
Q: Interleukin-22
R: Interleukin-10 receptor subunit beta
hetero molecules


Theoretical massNumber of molelcules
Total (without water)64,8435
Polymers64,0523
Non-polymers7922
Water543
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
11
S: Interleukin-22 receptor subunit alpha-1
T: Interleukin-22
U: Interleukin-10 receptor subunit beta
hetero molecules


Theoretical massNumber of molelcules
Total (without water)64,9905
Polymers64,0523
Non-polymers9382
Water543
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
12
V: Interleukin-22 receptor subunit alpha-1
W: Interleukin-22
X: Interleukin-10 receptor subunit beta
hetero molecules


Theoretical massNumber of molelcules
Total (without water)64,7865
Polymers64,0523
Non-polymers7352
Water543
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Unit cell
Length a, b, c (Å)134.487, 145.219, 152.038
Angle α, β, γ (deg.)71.062, 81.836, 62.475
Int Tables number1
Space group name H-MP1
Space group name HallP1
Symmetry operation#1: x,y,z
Noncrystallographic symmetry (NCS)NCS domain:
IDEns-ID
11
21
31
41
51
61
71
81
91
101
111
121
12
22
32
42
52
62
72
82
92
102
112
122
13
23
33
43
53
63
73
83
93
103
113
123

NCS domain segments:
Dom-IDComponent-IDEns-IDSelection detailsAuth asym-IDAuth seq-ID
111(chain '0' and (resid 20 or (resid 21 and (name...020 - 159
121(chain '0' and (resid 20 or (resid 21 and (name...0167 - 212
231(chain '3' and (resid 20 or (resid 21 and (name...320 - 159
241(chain '3' and (resid 20 or (resid 21 and (name...3167 - 212
351(chain '6' and (resid 20 or (resid 21 and (name...620 - 159
361(chain '6' and (resid 20 or (resid 21 and (name...6167 - 212
471(chain '9' and (resid 20 or (resid 21 and (name...920 - 159
481(chain '9' and (resid 20 or (resid 21 and (name...9167 - 212
591(chain 'C' and (resid 20 or (resid 21 and (name...C20 - 159
5101(chain 'C' and (resid 20 or (resid 21 and (name...C167 - 212
6111(chain 'E' and (resid 20 or (resid 21 and (name...E20 - 159
6121(chain 'E' and (resid 20 or (resid 21 and (name...E167 - 212
7131(chain 'H' and (resid 20 or (resid 21 and (name...H20 - 159
7141(chain 'H' and (resid 20 or (resid 21 and (name...H167 - 212
8151(chain 'K' and (resid 20 through 25 or (resid 26...K20 - 159
8161(chain 'K' and (resid 20 through 25 or (resid 26...K167 - 212
9171(chain 'O' and (resid 20 or (resid 21 and (name...O20 - 159
9181(chain 'O' and (resid 20 or (resid 21 and (name...O167 - 212
10191(chain 'R' and (resid 20 or (resid 21 and (name...R20 - 159
10201(chain 'R' and (resid 20 or (resid 21 and (name...R167 - 212
11211(chain 'U' and (resid 20 or (resid 21 and (name...U20 - 159
11221(chain 'U' and (resid 20 or (resid 21 and (name...U167 - 212
12231(chain 'X' and (resid 20 or (resid 21 and (name...X20 - 159
12241(chain 'X' and (resid 20 or (resid 21 and (name...X167 - 212
1252(chain '1' and (resid 24 through 62 or (resid 63...124 - 225
2262(chain '4' and (resid 24 through 62 or (resid 63...424 - 225
3272(chain '7' and (resid 24 through 62 or (resid 63...724 - 225
4282(chain 'A' and (resid 24 through 62 or (resid 63...A24 - 225
5292(chain 'B' and (resid 24 through 62 or (resid 63...B24 - 225
6302(chain 'F' and (resid 24 through 57 or (resid 58...F24 - 225
7312(chain 'I' and (resid 24 through 57 or (resid 58...I24 - 225
8322(chain 'M' and (resid 24 through 57 or (resid 58...M24 - 225
9332(chain 'P' and (resid 24 through 57 or (resid 58...P24 - 225
10342(chain 'S' and (resid 24 through 57 or (resid 58...S24 - 224
10352(chain 'S' and (resid 24 through 57 or (resid 58...S247
11362(chain 'V' and (resid 24 through 57 or (resid 58...V24 - 225
12372(chain 'Y' and (resid 24 through 57 or (resid 58...Y24 - 225
1383(chain '2' and (resid 40 or (resid 41 and (name...240 - 180
2393(chain '5' and (resid 40 or (resid 41 and (name...540 - 180
3403(chain '8' and (resid 40 or (resid 41 and (name...840 - 179
3413(chain '8' and (resid 40 or (resid 41 and (name...8192
4423(chain 'D' and (resid 40 or (resid 41 and (name...D40 - 180
5433(chain 'G' and (resid 40 or (resid 41 and (name...G40 - 180
6443(chain 'J' and (resid 40 or (resid 41 and (name...J40 - 180
7453(chain 'L' and (resid 40 or (resid 41 and (name...L40 - 180
8463(chain 'N' and (resid 40 or (resid 41 and (name...N40 - 180
9473(chain 'Q' and (resid 40 through 77 or (resid 78...Q40 - 180
10483(chain 'T' and (resid 40 or (resid 41 and (name...T40 - 180
11493(chain 'W' and (resid 40 or (resid 41 and (name...W40 - 180
12503(chain 'Z' and (resid 40 or (resid 41 and (name...Z40 - 180

NCS ensembles :
ID
1
2
3

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Components

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Protein , 3 types, 36 molecules 0369CEHKORUX147ABFIMPSVY258DGJ...

#1: Protein
Interleukin-10 receptor subunit beta / IL-10RB / Cytokine receptor class-II member 4 / Cytokine receptor family 2 member 4 / CRF2-4 / ...IL-10RB / Cytokine receptor class-II member 4 / Cytokine receptor family 2 member 4 / CRF2-4 / Interleukin-10 receptor subunit 2 / IL-10R2


Mass: 23808.438 Da / Num. of mol.: 12
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Mus musculus (house mouse) / Gene: Il10rb, Crfb4 / Production host: Trichoplusia ni (cabbage looper) / References: UniProt: Q61190
#2: Protein
Interleukin-22 receptor subunit alpha-1 / IL-22RA1


Mass: 23256.469 Da / Num. of mol.: 12
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Mus musculus (house mouse) / Gene: Il22ra1 / Production host: Trichoplusia ni (cabbage looper) / References: UniProt: Q80XZ4
#3: Protein
Interleukin-22 / IL-22 / IL-10-related T-cell-derived-inducible factor / IL-TIF / IL-TIF alpha / Interleukin-22a / IL-22a


Mass: 16986.719 Da / Num. of mol.: 12
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Mus musculus (house mouse) / Gene: Il22, Il22a, Iltif, Iltifa / Production host: Trichoplusia ni (cabbage looper) / References: UniProt: Q9JJY9

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Sugars , 9 types, 24 molecules

#4: Polysaccharide beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1- ...beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 732.682 Da / Num. of mol.: 3
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
DManpb1-4DGlcpNAcb1-4[LFucpa1-6]DGlcpNAcb1-Glycam Condensed SequenceGMML 1.0
WURCS=2.0/3,4,3/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1221m-1a_1-5]/1-1-2-3/a4-b1_a6-d1_b4-c1WURCSPDB2Glycan 1.1.0
[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{}}[(6+1)][a-L-Fucp]{}}}LINUCSPDB-CARE
#5: Polysaccharide
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta- ...2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 570.542 Da / Num. of mol.: 7
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
DGlcpNAcb1-4[LFucpa1-6]DGlcpNAcb1-Glycam Condensed SequenceGMML 1.0
WURCS=2.0/2,3,2/[a2122h-1b_1-5_2*NCC/3=O][a1221m-1a_1-5]/1-1-2/a4-b1_a6-c1WURCSPDB2Glycan 1.1.0
[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}[(6+1)][a-L-Fucp]{}}}LINUCSPDB-CARE
#6: Polysaccharide
alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 367.349 Da / Num. of mol.: 7
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
LFucpa1-6DGlcpNAcb1-Glycam Condensed SequenceGMML 1.0
WURCS=2.0/2,2,1/[a2122h-1b_1-5_2*NCC/3=O][a1221m-1a_1-5]/1-2/a6-b1WURCSPDB2Glycan 1.1.0
[]{[(4+1)][b-D-GlcpNAc]{[(6+1)][a-L-Fucp]{}}}LINUCSPDB-CARE
#7: Polysaccharide alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 367.349 Da / Num. of mol.: 1
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
LFucpa1-3DGlcpNAcb1-Glycam Condensed SequenceGMML 1.0
WURCS=2.0/2,2,1/[a2122h-1b_1-5_2*NCC/3=O][a1221m-1a_1-5]/1-2/a3-b1WURCSPDB2Glycan 1.1.0
[]{[(4+1)][b-D-GlcpNAc]{[(3+1)][a-L-Fucp]{}}}LINUCSPDB-CARE
#8: Polysaccharide beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta- ...beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 586.542 Da / Num. of mol.: 1
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-Glycam Condensed SequenceGMML 1.0
WURCS=2.0/2,3,2/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5]/1-1-2/a4-b1_b4-c1WURCSPDB2Glycan 1.1.0
[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{}}}}LINUCSPDB-CARE
#9: Polysaccharide beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1- ...beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 878.823 Da / Num. of mol.: 2
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
DManpb1-4DGlcpNAcb1-4[LFucpa1-3][LFucpa1-6]DGlcpNAcb1-Glycam Condensed SequenceGMML 1.0
WURCS=2.0/3,5,4/[a2122h-1b_1-5_2*NCC/3=O][a1221m-1a_1-5][a1122h-1b_1-5]/1-2-1-3-2/a3-b1_a4-c1_a6-e1_c4-d1WURCSPDB2Glycan 1.1.0
[]{[(4+1)][b-D-GlcpNAc]{[(3+1)][a-L-Fucp]{}[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{}}[(6+1)][a-L-Fucp]{}}}LINUCSPDB-CARE
#10: Polysaccharide 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 424.401 Da / Num. of mol.: 1
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
DGlcpNAcb1-4DGlcpNAcb1-Glycam Condensed SequenceGMML 1.0
WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1WURCSPDB2Glycan 1.1.0
[]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}}LINUCSPDB-CARE
#11: Polysaccharide alpha-L-fucopyranose-(1-3)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose


Type: oligosaccharide / Mass: 513.490 Da / Num. of mol.: 1
Source method: isolated from a genetically manipulated source
DescriptorTypeProgram
LFucpa1-3[LFucpa1-6]DGlcpNAcb1-Glycam Condensed SequenceGMML 1.0
WURCS=2.0/2,3,2/[a2122h-1b_1-5_2*NCC/3=O][a1221m-1a_1-5]/1-2-2/a3-b1_a6-c1WURCSPDB2Glycan 1.1.0
[]{[(4+1)][b-D-GlcpNAc]{[(3+1)][a-L-Fucp]{}[(6+1)][a-L-Fucp]{}}}LINUCSPDB-CARE
#13: Sugar ChemComp-NAG / 2-acetamido-2-deoxy-beta-D-glucopyranose / N-acetyl-beta-D-glucosamine / 2-acetamido-2-deoxy-beta-D-glucose / 2-acetamido-2-deoxy-D-glucose / 2-acetamido-2-deoxy-glucose / N-ACETYL-D-GLUCOSAMINE


Type: D-saccharide, beta linking / Mass: 221.208 Da / Num. of mol.: 1
Source method: isolated from a genetically manipulated source
Formula: C8H15NO6
IdentifierTypeProgram
DGlcpNAcbCONDENSED IUPAC CARBOHYDRATE SYMBOLGMML 1.0
N-acetyl-b-D-glucopyranosamineCOMMON NAMEGMML 1.0
b-D-GlcpNAcIUPAC CARBOHYDRATE SYMBOLPDB-CARE 1.0
GlcNAcSNFG CARBOHYDRATE SYMBOLGMML 1.0

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Non-polymers , 2 types, 347 molecules

#12: Chemical
ChemComp-GOL / GLYCEROL / GLYCERIN / PROPANE-1,2,3-TRIOL


Mass: 92.094 Da / Num. of mol.: 7 / Source method: obtained synthetically / Formula: C3H8O3
#14: Water ChemComp-HOH / water


Mass: 18.015 Da / Num. of mol.: 340 / Source method: isolated from a natural source / Formula: H2O

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Details

Has ligand of interestN
Has protein modificationY

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Experimental details

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Experiment

ExperimentMethod: X-RAY DIFFRACTION / Number of used crystals: 1

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Sample preparation

CrystalDensity Matthews: 3.24 Å3/Da / Density % sol: 62.04 %
Crystal growTemperature: 293 K / Method: vapor diffusion, hanging drop
Details: 12.5% PEG 3350, 0.2 M sodium pottassium phosphate, 0.1 M HEPES pH 8.0

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Data collection

DiffractionMean temperature: 100 K / Serial crystal experiment: N
Diffraction sourceSource: SYNCHROTRON / Site: APS / Beamline: 23-ID-B / Wavelength: 1.03317 Å
DetectorType: DECTRIS EIGER X 16M / Detector: PIXEL / Date: Dec 6, 2019
RadiationProtocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelengthWavelength: 1.03317 Å / Relative weight: 1
ReflectionResolution: 2.6→48.09 Å / Num. obs: 289478 / % possible obs: 97.5 % / Redundancy: 2.9 % / Biso Wilson estimate: 69.08 Å2 / CC1/2: 0.994 / Rmerge(I) obs: 0.095 / Rpim(I) all: 0.066 / Rrim(I) all: 0.116 / Net I/σ(I): 6.5
Reflection shellResolution: 2.6→2.67 Å / Num. unique obs: 14313 / CC1/2: 0.331

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Processing

Software
NameVersionClassification
PHENIX1.17.1_3660refinement
XDSdata reduction
Aimlessdata scaling
PHENIXphasing
RefinementMethod to determine structure: MOLECULAR REPLACEMENT
Starting model: 3DGC, 3LQM

3dgc

3lqm


Resolution: 2.6→48.09 Å / SU ML: 0.4546 / Cross valid method: FREE R-VALUE / σ(F): 1.96 / Phase error: 34.9692
RfactorNum. reflection% reflection
Rfree0.2963 1998 0.69 %
Rwork0.2363 --
obs0.2367 289145 97.45 %
Solvent computationShrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å
Displacement parametersBiso mean: 101.13 Å2
Refinement stepCycle: LAST / Resolution: 2.6→48.09 Å
ProteinNucleic acidLigandSolventTotal
Num. atoms51932 0 880 340 53152
Refine LS restraints
Refine-IDTypeDev idealNumber
X-RAY DIFFRACTIONf_bond_d0.011154088
X-RAY DIFFRACTIONf_angle_d1.323173460
X-RAY DIFFRACTIONf_chiral_restr0.07158351
X-RAY DIFFRACTIONf_plane_restr0.00949314
X-RAY DIFFRACTIONf_dihedral_angle_d19.802320193
LS refinement shell
Resolution (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkRefine-ID% reflection obs (%)
2.6-2.670.36251430.337720402X-RAY DIFFRACTION97.12
2.67-2.740.37831420.339420588X-RAY DIFFRACTION97.58
2.74-2.820.37771430.328620560X-RAY DIFFRACTION97.77
2.82-2.910.3481430.315920600X-RAY DIFFRACTION97.9
2.91-3.010.36791430.30520558X-RAY DIFFRACTION97.91
3.01-3.130.3611430.301220601X-RAY DIFFRACTION97.75
3.13-3.280.3991430.29820576X-RAY DIFFRACTION97.56
3.28-3.450.30951430.27220560X-RAY DIFFRACTION97.57
3.45-3.660.34551430.253320468X-RAY DIFFRACTION97.55
3.66-3.950.32741430.236320493X-RAY DIFFRACTION97.26
3.95-4.340.26441420.207620425X-RAY DIFFRACTION96.97
4.34-4.970.21371410.185720401X-RAY DIFFRACTION96.87
4.97-6.260.27311440.204320514X-RAY DIFFRACTION97.63
6.26-48.090.2581420.205220401X-RAY DIFFRACTION96.84
Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

IDL11 (°2)L12 (°2)L13 (°2)L22 (°2)L23 (°2)L33 (°2)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T11 (Å2)T12 (Å2)T13 (Å2)T22 (Å2)T23 (Å2)T33 (Å2)Origin x (Å)Origin y (Å)Origin z (Å)
18.5048-3.3286-4.56865.38992.15172.51870.52160.8758-1.2821-0.7474-0.43520.07790.35310.7451-0.12061.10960.7117-0.54731.2857-0.27631.203779.096-41.897-52.149
29.3821-3.5071-3.58074.68670.91033.83590.60830.8839-1.1631-0.1808-0.47830.20660.06840.1822-0.10890.80810.3099-0.34260.8342-0.14720.88263.536-33.084-46.245
36.9402-1.8578-0.02895.42750.81933.2279-0.8219-0.2256-1.96251.0420.25910.96981.58080.06970.30361.1660.18790.12310.64710.12041.268244.234-38.091-35.379
44.51764.77452.86595.09563.5886.1920.0974-1.52091.77610.3738-1.39911.9364-0.6798-1.8891.02961.0146-0.93940.40991.9875-1.15511.565120.37655.11348.44
50.24920.03320.72743.52682.81554.23210.2702-0.75650.08310.7404-0.84670.7036-0.11-1.0990.44291.9181-0.98380.25162.3521-0.87780.742223.79254.80263.064
62.8946-0.8021-1.36510.39740.98722.58520.6454-1.15620.66230.4203-0.5711-0.0208-0.5588-0.0547-0.75931.468-1.02450.44042.1581-0.57380.682928.67952.26255.272
72.1231-0.6082-1.50280.3390.32751.11640.4941-0.65430.67760.8886-0.88230.7089-0.2455-0.3103-0.82860.9653-1.09850.7532.4304-0.7281.02820.45950.29354.423
85.09460.92990.45174.07714.79575.76830.8729-0.6888-0.19060.51710.2661-1.00980.529-0.3112-0.99860.5731-0.2601-0.11230.5510.15160.759642.12929.12629.783
95.49981.4177-3.92327.36971.19254.15730.6119-0.52950.21911.2984-0.4068-0.4362-0.60611.1475-0.04941.3327-0.8447-0.15331.72020.24920.599140.33238.44154.1
100.1098-0.347-0.64021.00412.00274.06240.5491-1.139-0.32541.1678-0.88890.06010.4605-0.16180.15431.2312-0.8417-0.05961.44730.02880.516232.25627.77840.305
111.90610.0623-0.62961.3675-0.95110.8981.2038-0.763-0.43290.3187-1.0658-0.17170.8921-0.58620.42230.646-1.0810.03661.18360.04840.659632.43226.08632.605
122.46160.46852.89199.11211.37844.4998-0.0988-0.0356-0.54340.0775-0.0174-1.02670.5022-1.00360.03230.5494-0.24310.13990.5840.23130.714338.83531.48822.417
131.41590.2343-2.00321.76050.20813.0111-0.2058-0.2035-0.35550.449-0.1829-0.05170.49580.33630.46371.9832-1.20670.07692.32150.82690.466825.919.44962.198
141.6008-0.2905-0.38450.92280.88721.16910.5576-1.00670.77020.2833-0.40530.2972-0.2903-0.5541-0.50291.5652-1.24130.62152.9214-0.40720.526613.40935.36558.083
155.0247-0.946-2.63090.9780.70691.6499-0.2129-1.56-0.66740.64020.08920.3760.04530.43250.38692.0618-1.20640.91962.7058-0.55631.485221.61139.56372.835
161.8301-0.3804-2.24293.9606-4.1458.17750.0138-0.9244-0.14581.4502-0.7222-0.1535-0.85180.68670.40072.3522-1.03330.5612.1193-0.27490.95615.46328.58272.608
171.79591.1505-1.37861.3122-1.1181.2468-0.2839-0.1468-0.62550.0791-0.3397-0.18230.13820.0773-0.05361.6881-2.09981.32512.6524-0.10990.817811.00922.83462.208
184.14711.0338-3.00696.3076-4.74634.82290.1499-1.0388-0.13571.6995-1.0988-1.2839-0.74111.81670.88193.4802-1.2843-0.48912.8080.88281.595425.00720.69580.152
190.88280.9452-0.63021.3852-0.83351.10090.1563-0.3456-0.18530.41050.0864-0.1404-0.2079-0.13920.00411.5634-2.02831.17912.8331-0.35791.016716.80734.17772.29
208.1461-0.1228-3.8442.1971-2.20644.1610.875-1.1614-0.32040.1497-0.07960.5472-0.86720.5011-0.47961.2412-1.4022-0.04721.91210.44290.7999-5.7985.97754.92
211.52730.2815-0.45381.1679-0.16261.27510.8834-1.1037-0.19560.228-0.0463-0.016-0.064-0.62980.2951.168-1.79260.12982.11680.50510.64598.61711.83748.849
225.38161.1445-2.00143.7686-1.08323.37340.4096-0.5965-1.1379-0.0623-0.4468-0.73610.9251-0.03170.0761.5666-0.9584-0.16241.38350.39771.069729.4717.40337.477
238.2161.8143-4.73794.8357-0.32067.57180.2119-1.4397-1.07680.6868-0.2113-0.5272-0.08820.73510.0831.8229-0.9913-0.21581.0040.25071.069324.8625.42837.881
243.4110.963-0.09416.29153.16287.03790.07620.63540.6765-0.5517-0.0395-0.2838-0.86871.1203-0.00280.74290.12670.09981.42170.43480.8432-11.92857.829-51.907
255.38111.0073-4.1584.6828-3.8037.29130.65210.62280.7876-0.0854-0.14950.2378-0.18150.7041-0.35040.53020.2921-0.04450.9421-0.00310.5893-20.51138.955-40.447
260.4884-0.12590.06912.5779-0.3292.20930.55210.5917-0.241-0.478-0.25480.34740.51870.9393-0.24470.66580.4853-0.07241.0936-0.05080.6419-23.64530.317-35.298
270.66231.85130.08655.5664-0.60141.8101-0.0987-0.1846-0.2811-1.57030.1846-0.1977-0.2045-1.0748-0.01981.17310.6682-0.12331.9991-0.45030.9019-13.88222.556-63.06
284.9139-0.61160.16984.22332.50481.55390.77441.33110.53180.4351-0.3367-0.38920.41580.8778-0.27761.19070.61240.16172.15780.15040.6895-1.92135.272-53.398
296.46310.1125-5.9834.1460.88646.98570.0699-0.83240.092-0.36870.0784-0.4778-0.94410.7297-0.48861.10330.49220.36912.30330.1450.6917-3.63647.955-65.37
300.22640.1820.03373.62032.35277.0585-0.08651.3255-0.1288-0.4217-0.2957-0.26050.37131.85060.31461.15780.45240.21322.10270.18151.1274-2.66533.669-68.897
312.3929-0.67150.06211.6713-1.69171.9803-0.2476-0.169-0.7805-0.2599-0.4368-0.01280.39750.50440.83181.05250.64520.02692.0963-0.2180.79940.90925.532-60.497
326.55631.9908-0.53333.06741.06282.2001-0.39341.14040.0368-1.6624-0.17120.114-0.5085-0.4960.49752.01760.93740.00372.1582-0.11640.8944-9.83825.885-78.026
338.23452.8431.0948.74911.72520.5902-0.1105-0.1351-0.8222-0.61510.2517-1.23530.02442.2867-0.0081.12510.34130.19171.91870.20660.87220.79641.654-72.228
345.61515.127-1.68065.1222-0.04165.6228-0.0574-0.54980.8226-0.28090.03381.395-0.7172-0.8327-0.12321.22820.69060.00171.43820.04190.8042-11.0332.563-63.308
357.11741.4858-1.92180.49380.20092.10220.50661.7402-0.8987-0.6961-0.6036-0.03690.0281-0.0644-0.07391.13230.9611-0.25262.0551-0.3070.920715.9626.628-54.265
361.7895-0.72121.06591.3064-0.67571.30770.28060.797-0.2062-0.345-0.2262-0.2555-0.07370.38850.03211.09641.3451-0.29772.5829-0.22360.931516.48810.119-56.188
372.5474-0.169-3.9021.87751.01266.33510.63390.97580.09170.27470.20550.09510.08411.1096-0.65060.97070.8174-0.29871.5448-0.20660.9038-6.13414.811-41.003
385.65470.5518-3.47133.1193-1.10045.39570.20520.4713-1.2637-0.4138-0.21010.36370.79980.25560.13531.20360.7021-0.18821.1083-0.37991.2448-19.1398.467-36.502
396.45730.1643-1.12754.9035-3.7044.20960.01661.6924-1.34990.1369-0.4084-0.2310.0255-0.91220.25571.34860.7409-0.34221.3711-0.44241.2416-14.3066.566-37.119
408.5236-0.69055.27152.1157-3.06937.5112-0.2291-0.89811.85930.9957-0.63020.7078-1.3402-0.99570.88661.1358-0.25890.21831.2895-0.39881.2412-50.9810.97544.774
411.4625-1.2959-2.22311.26772.28524.19061.1402-0.96130.57011.3723-0.93991.4025-0.1897-1.863-0.59781.7193-0.83220.74852.4955-0.63341.426-48.67211.72259.452
423.7283.24-0.08523.3051-2.08958.39570.5367-1.06841.23631.0948-1.05411.1063-1.7375-0.0354-0.60351.8126-0.96371.04491.9245-0.67941.3462-48.20912.19352.571
434.59990.3121-3.13.21731.67476.48520.6841-1.5491-0.14220.9581-0.7256-0.11240.03610.37010.1420.8273-0.4779-0.05551.1740.28520.853-32.396-6.09142.838
442.46150.005-0.17872.89561.89113.36270.5221-0.999-0.63950.3251-0.2783-0.23810.5469-0.0081-0.23770.5836-0.2676-0.14270.86880.30880.8441-32.167-17.10732.353
452.1563-1.9359-0.51643.79752.77715.55870.1794-0.3123-0.32010.1118-0.2712-0.44730.2657-0.60890.01780.6322-0.2057-0.16321.24260.51630.8764-33.967-11.80331.49
462.22231.1598-0.07832.9032-0.65951.09290.4384-1.14270.22370.6816-0.5160.41640.1012-0.1519-0.15071.4574-0.83760.012.01470.27130.5438-49.726-14.757.062
470.64590.0107-0.86081.7318-0.94221.87930.1595-0.9374-0.05150.56570.09480.6272-0.4260.363-0.21041.6393-1.350.4833.30680.3410.686-52.021-13.16168.792
481.79430.7724-0.73172.7386-0.83893.30930.9615-1.8257-0.14311.3645-0.8764-1.0887-0.36391.36620.61661.5829-1.1722-0.06263.29870.83760.9972-48.762-22.82769.02
491.88270.1024-2.09541.2110.15572.79790.3421-0.9459-0.26550.89320.01630.1422-0.40120.8472-0.26051.7855-1.45930.74333.00980.2411.1545-51.859-10.34969.248
506.77753.3768-4.34878.0945-2.65975.03780.1829-1.056-1.01130.6427-0.839-0.2310.45440.44510.50051.0517-0.4457-0.45121.45920.72931.3765-68.2-42.79853.501
510.03260.30990.05032.4720.67820.19691.2203-1.8381-1.51340.9662-1.0324-0.0725-0.00140.0809-0.1631.0109-0.5933-0.47461.73790.75471.444-66.507-39.2155.852
526.9896-1.3765-2.41833.96250.247.6463-0.0442-0.3736-0.8771-0.43890.3447-0.44840.1186-0.5228-0.28620.8821-0.3911-0.25790.90780.36781.1937-40.552-30.81538.4
538.93772.6012-6.59856.5256-2.79295.1968-1.42060.0433-2.0091-1.09460.3541-0.59512.17820.7031.17611.0825-0.30670.01791.08340.19331.5458-35.225-37.88335.143
548.31825.2704-3.35949.4042-5.19126.55040.05610.2637-0.7716-0.1463-0.4971-0.15490.4581-0.35530.51540.44910.0057-0.02140.5171-0.16480.521925.339-6.03-26.762
559.62865.78887.21173.5194.3835.4621.3493-0.8568-2.59550.7487-0.573-0.2643.8514-0.852-0.71081.5249-0.3811-0.16090.96480.16891.472820.915-22.191-24.849
566.0238-1.6716-4.48088.84774.38944.78710.21660.6877-0.2029-0.3081-0.64420.51670.497-2.11940.29020.3951-0.0119-0.13720.8599-0.23250.654112.018-5.609-31.79
576.4367-1.0689-1.6211.50341.30995.4625-0.33280.4278-1.5957-1.2996-0.07990.57730.8019-0.56570.31460.77670.0746-0.02430.5511-0.33250.910521.299-15.053-34.08
585.69631.3414-5.41818.0731-0.60689.09490.58841.09820.8935-1.2838-0.83390.1555-1.3435-1.70230.13330.58430.3095-0.05710.8031-0.12350.572620.614.108-34.421
595.76452.6460.43721.612-1.60018.56770.27280.475-1.1193-0.0574-0.1383-0.99881.2927-1.163-0.1380.3647-0.0766-0.03490.811-0.30461.142813.11-12.999-25.699
608.71583.1362-4.99041.7947-2.08893.86210.32150.314-0.39710.0772-0.3444-0.2425-0.2493-0.1804-0.00980.44670.07520.06120.3926-0.06770.517938.3375.544-29.405
614.16581.37866.3540.59252.05569.7785-0.32461.04710.0206-0.3027-0.0594-0.1386-0.5322-0.41640.38710.60650.18810.11290.57290.14690.524237.5710.031-38.901
625.9169-4.79625.13943.8341-4.00737.1975-0.21490.78990.43290.521-0.4217-0.226-0.6680.23940.73780.55130.04880.09590.46160.03340.591640.91913.233-28.467
634.1207-4.04314.68923.9275-4.57395.30170.8138-0.9569-1.65071.0021-0.03470.66740.0456-0.0502-0.72421.0032-0.0423-0.03350.61680.1820.790255.80710.575-19.294
643.70241.66584.72963.8092-1.18129.80.26151.16170.2113-0.2165-0.10020.03310.26130.9297-0.15610.58010.04370.06010.53570.2030.754556.68713.4-30.492
656.45250.0774-2.07012.08791.91316.11420.3587-1.0105-1.3791-0.5791-0.6253-0.28740.20550.7920.23040.56160.070.03690.73190.18070.558249.4167.005-25.782
663.1893-2.3659-3.84897.14260.83695.444-0.0278-1.7324-1.2058-0.33210.0125-0.11250.26591.24240.05590.45870.04670.00710.6464-0.00340.31749.3816.238-27.482
676.1861-3.0969-1.07754.76870.11375.72610.1405-0.4851-0.58770.552-0.3765-0.06610.43010.76610.18210.492-0.0885-0.05830.69410.28660.6089-9.655-7.09830.304
688.1340.61622.00872.4733-0.81553.15560.2412-0.3360.17560.2051-0.31330.6181-0.0237-0.09920.04120.7191-0.05310.20030.5164-0.0690.7304-37.9449.88631.5
695.0364-1.18550.68758.08725.07644.7564-0.1282-0.92030.86180.00450.4038-0.0003-0.5260.6284-0.27540.6892-0.01320.1080.6677-0.13560.519329.137.28510.381
708.5793-2.2786-2.35044.7388-4.83937.92310.52490.017-0.3462-0.4753-0.37710.80750.5105-1.3087-0.29230.59270.0307-0.08280.9341-0.25740.562120.87929.069.29
710.65060.94520.30321.7679-0.10823.7627-0.0711-0.43650.24670.1039-0.18110.1809-0.0269-0.72340.31620.5260.0834-0.01270.5364-0.13180.368328.26530.9040.792
723.0768-2.0578-4.75313.64322.32427.9861-0.4412-0.6775-0.38730.10030.1555-0.1710.8153-0.08380.36010.51130.0298-0.00350.33340.06050.533342.93821.468-13.501
736.74272.7959-1.43684.77270.58265.6725-0.1205-0.4444-0.4718-0.2367-0.0375-0.5015-0.10210.57180.15020.5147-0.0046-0.00180.4080.16310.598854.67130.209-16.239
748.89970.20431.15527.32661.14451.9020.037-1.0581.468-0.0348-0.4367-0.1938-0.5773-0.27680.38080.5962-0.06190.06970.7545-0.00580.6237-13.95926.84824.973
753.2543-5.5871-1.52779.95692.37910.87570.31071.2721-1.129-0.148-0.87370.2311-0.2995-0.01670.5740.4746-0.05420.10610.706-0.01230.5829-12.60811.01715.904
767.238-2.27816.00841.399-3.27697.80140.1250.2302-1.38940.5415-0.37860.0228-0.86462.10690.23240.4426-0.16110.05441.24720.14330.79581.8344.49723.058
776.0612-5.8933-0.89955.97230.13722.3367-0.3564-1.8808-0.10581.62450.3988-0.44551.04341.11580.05930.9366-0.1727-0.15981.2780.41831.01523.99517.05233.743
782.6099-0.03153.55779.58855.66588.2905-0.209-0.4830.6355-0.57870.0227-1.0785-0.53951.45860.250.5019-0.1447-0.03410.94930.2260.97781.28923.55823.244
792.9702-1.67220.75744.1791.92831.8935-1.45231.8097-0.637-1.75830.3683-1.27390.05032.95981.11390.9778-0.24420.27921.54880.17691.0467-3.82213.0387.875
806.09841.40553.25392.73272.82829.0684-1.08121.10490.8106-0.854-0.0416-0.0614-0.64941.32340.95520.7094-0.0994-0.13320.93660.37980.5665-8.3923.41113.338
817.83345.21586.25159.21655.85855.4859-1.1484-0.32813.39410.3156-0.2294-1.406-2.59542.21391.3451.3272-0.3409-0.34181.30260.18041.58253.44932.07628.317
828.36191.49180.91346.8182.03228.4374-0.23010.83130.1550.03090.0425-1.5003-0.75242.12090.23440.5192-0.1069-0.04721.07840.5160.98978.08614.25921.522
832.7951-4.1926-0.80966.41731.4848.6878-0.7837-0.6225-0.34290.6883-0.2347-0.458-0.12530.3381.08910.8193-0.315-0.02230.87990.18240.7132-7.55417.98326.042
842.9592.4493-0.11098.1435-4.89456.0185-0.05121.15280.92550.29840.43890.6678-1.0334-0.7995-0.35820.67540.1871-0.02710.73160.19690.6084-19.90836.705-7.773
853.87662.4454-1.48218.50894.084.61380.40920.601-0.64590.9266-0.4425-0.81040.10681.9289-0.07560.611-0.052-0.12071.08070.21450.5559-11.45429.513-8.536
863.37732.6114-2.90077.7698-8.25779.14130.0370.23360.06-0.125-0.8432-0.6090.20071.040.77210.5498-0.0209-0.05460.83630.18910.4825-12.34929.963-1.491
877.40250.0632-4.27652.5297-2.16896.1374-0.47810.3903-0.5716-0.4021-0.1275-0.30870.11320.49340.63240.4927-0.0396-0.04670.36310.00540.4334-23.48330.8323.181
886.909-2.3612-1.28573.9079-0.70464.4377-0.22860.1105-0.6349-0.154500.53740.2432-0.27680.29150.4441-0.1016-0.02590.3059-0.03350.5731-37.10225.51515.875
896.863-4.5319-3.53367.42263.58276.771-0.0846-0.8907-0.3365-0.33950.39661.81460.2095-0.6413-0.24360.7213-0.09930.1930.44160.06281.4274-51.81525.18121.402
904.6279-1.2776-3.20986.865-2.17966.9521-0.11281.34270.0092-0.2534-0.20780.474-0.001-0.00570.14830.55670.02970.02970.5065-0.16210.6714-39.7630.25714.626
912.0288-2.57261.13117.46191.6366.80730.40740.4051-1.3671-0.0456-0.4814-1.65051.02540.60780.25710.6890.06360.15160.76040.54521.96552.171-60.48624.282
922.7257-1.6164-0.54111.690.88730.76910.4842-0.2661-0.6846-0.2976-0.9857-0.03350.83020.92210.42720.96050.21180.02441.12790.68451.391661.966-59.08229.546
931.02180.44290.34290.6217-0.57484.74790.0476-0.2744-0.22380.0437-0.2845-1.58350.54941.46090.130.72510.15390.33460.9520.53481.586260.56-55.44126.91
941.9385-0.3571-0.44993.0047-0.35432.17940.298-0.16270.12110.2389-0.7069-1.1158-0.28650.46250.29620.6203-0.0688-0.12960.69170.4210.829742.046-40.98635.944
951.5434-1.51170.28378.5005-3.35334.6902-0.23790.8620.2222-0.3524-0.3164-0.6894-0.52640.3890.5560.51890.03740.05330.65710.20760.414936.07-35.05330.956
968.16390.5191-2.43095.66470.65841.1361-0.25560.26510.3114-0.4671-0.01870.6901-0.3773-0.16860.30320.6740.0135-0.13150.68260.19130.444324.638-35.41831.304
978.94.7883-7.14897.2259-3.53978.756-0.2611.2543-0.0289-0.42160.0139-0.03380.4613-0.91510.2820.4763-0.0644-0.0820.49850.14070.318429.166-40.90831.67
985.8484-1.66810.59055.7876-3.09962.02630.5409-0.39231.35150.8389-0.38240.3649-1.08511.4787-0.0891.1859-0.4272-0.06290.85260.17960.748655.848-22.14425.451
994.7728-3.4735-0.39935.16520.78680.4934-0.13990.0893-0.92380.4257-0.7004-0.12810.23260.92540.86520.7026-0.08990.07640.83640.36570.879353.945-36.83714.707
1002.69983.14760.42487.9417-0.27662.53150.0307-0.3255-0.60310.3851-0.3642-0.04930.77650.40790.41090.7242-0.04960.12031.52050.79861.54568.68-45.2118.888
1013.4928-2.68191.32182.845-0.93360.5094-0.0233-2.4092-1.53013.42050.27521.17220.4941-0.8336-0.37791.2963-0.0286-0.08612.26671.0141.611672.099-36.36928.271
1021.94760.17441.65073.16893.61465.18660.0796-0.23040.1460.4676-0.3365-0.7902-0.31581.49420.14510.9257-0.4168-0.12421.7030.59391.220370.989-26.89123.769
1038.64635.7192-2.75919.4034-1.02094.1232-1.28573.90680.1422-2.49941.0567-1.1932-0.2620.28240.12041.0876-0.09730.261.43630.33151.072262.042-34.3395.693
1047.58060.55224.16733.24432.63594.0303-0.55180.82190.8707-0.7186-0.2198-0.2552-1.52781.4730.57350.6705-0.10020.02130.80890.40870.967358.438-25.99611.871
1059.6803-5.01925.08672.6442-2.5612.854-1.24470.60551.8667-0.72980.5609-1.2749-0.0310.31020.82741.3559-0.4519-0.3531.2780.44591.814472.158-18.68724.734
1060.2605-0.6799-0.42122.7337-0.1282.3149-0.3150.9811.0144-0.71111.0054-0.2968-0.55980.6653-0.54960.8442-0.35150.12171.91480.51471.546478.975-33.81420.065
1079.18060.7341-2.52443.55810.67966.1465-0.5317-0.7059-0.7980.4622-0.3396-0.4834-0.10191.22130.76470.5545-0.25270.140.9060.52411.353264.288-34.97619.361
1087.32227.1796-5.99357.9917-6.27425.1083-0.3860.65370.79780.12920.98640.52570.5688-1.1959-0.61630.7719-0.1004-0.03930.79870.2740.518347.431-10.394-2.339
1090.91931.8666-2.70945.2439-6.51548.6579-0.44881.6841.2751-0.60010.71290.4802-0.7672-2.4007-0.34780.9635-0.0918-0.18930.9890.40340.779348.318-4.198-16.157
1106.53285.371-3.3428.7371.61636.6560.16810.31760.050.43040.00940.00271.03740.4267-0.39950.80210.01450.01240.68280.28460.71854.51-17.446-7.522
1113.04410.53630.16317.4244-4.52864.5232-0.0122-0.90330.0125-0.5236-0.8203-0.31891.2670.83540.93070.7645-0.0322-0.03220.73830.16530.495254.12-17.2790.048
1124.73181.3986-0.6624.454-4.35884.39620.2736-0.16770.19140.5743-0.5423-0.0071-0.96981.44480.10810.7982-0.10950.03190.60320.2790.731355.699-10.674-3.832
1137.65993.5119-4.49815.9642-2.53265.7804-0.13041.49470.68540.13010.73390.79790.5716-1.6025-0.67740.72820.0264-0.1150.83440.36910.754725.53-22.92519.938
1146.1191-5.4118-6.14915.09276.28528.52310.36470.7536-1.1532-0.92-0.95740.2037-0.20740.09130.48081.1871-0.1874-0.06090.79410.05780.961941.313-29.0948.967
1156.719-3.6781-0.61952.50721.29642.72190.34720.55681.3574-0.62360.30580.5159-0.6612-0.2861-0.58110.9037-0.0010.11090.59610.41021.028531.898-17.27621.082
1165.8225-5.48243.14498.5122-4.87485.49770.62480.47741.67860.36260.29282.5719-0.6868-1.0926-0.66711.24880.09560.22190.61510.21561.662328.074-13.91126.78
1175.677-0.544-3.11335.2668-1.67126.21680.75911.07572.03210.84630.21750.8125-1.3561-0.6737-0.82020.88420.10030.00980.57260.26971.057327.613-16.63523.414
1186.15886.579-0.27719.1169-2.2453.29540.66672.69171.3165-0.16370.38132.3558-1.2661-0.9521-0.92080.76010.1407-0.14631.04040.38261.577417.301-18.87519.095
1197.54850.297-2.79083.9837-4.1927.54150.7816-0.80620.8072-0.3164-1.2611-0.8417-1.5041.190.59791.0910.01660.25420.65950.08330.913210.8298.94896.17
1201.61030.8003-0.29272.00612.73775.1160.53560.6131.1487-1.2108-0.56520.0174-0.93960.3336-0.03091.90930.50040.25490.68380.3150.94396.4248.74781.61
1213.2242-0.68290.76287.8743-1.79680.54040.51480.59970.3153-1.0442-0.2320.6558-0.7629-0.4942-0.23461.40550.47230.22540.77180.10570.60451.9136.52489.795
1225.59811.9076-3.47743.7158-4.62766.14080.56060.24940.7283-0.5511-0.7006-0.2452-0.38540.51610.23711.1040.35810.13970.64080.12430.570310.2864.07490.069
1233.23121.5025-3.19387.0778-3.93274.61940.1970.5174-0.1958-0.7346-0.03071.09890.4999-0.5389-0.28310.37720.1226-0.16190.4841-0.14120.9582-10.628-11.516104.948
1240.56170.6004-1.34242.4709-1.31216.25410.5827-0.17360.0096-0.20880.09680.78150.1917-0.3351-0.51060.62410.3165-0.24060.42530.08920.7049-2.404-17.249103.156
1251.48890.2479-0.24792.334-0.74965.09210.2051-0.1286-0.43980.07380.14630.67890.66350.2579-0.26220.60280.176-0.02630.3288-0.07730.8152-2.753-20.452116.803
1263.0231-1.1341-2.49944.0420.14589.2101-0.3035-0.1747-0.0125-0.01690.02930.63810.34310.41610.20810.46330.15410.07250.3328-0.16210.8112-1.588-13.806113.534
1274.95854.59544.51224.23994.12869.87620.82851.0333-0.8226-0.14670.2207-0.31832.62490.0919-1.12421.16580.2318-0.2810.7282-0.05960.66833.111-26.77783.553
1289.78527.2014-6.22135.3535-4.8036.68850.6135-0.38-0.47310.1882-1.095-0.7817-0.38950.90720.55040.92190.2301-0.07290.61440.06930.497515.818-14.39988.849
1295.05043.13.10187.00693.07757.45780.58161.31921.0966-1.6466-0.40951.169-0.7330.4330.0891.4340.51660.10891.00690.30561.026210.381-4.67574.146
1305.0708-0.56624.28593.8755-0.55647.59941.02241.52820.2172-1.2017-0.83210.15240.59730.93-0.16891.66760.6016-0.07221.1320.09910.69813.318-18.1473.209
1318.7927-3.18550.19462.1837-2.09034.2638-0.212-0.2038-0.7968-0.3665-0.1865-0.2310.62510.59530.33271.00460.5143-0.0130.7922-0.09260.621117.865-23.65483.004
1324.4551-5.24514.49137.5432-6.22155.15751.12882.0895-0.9267-2.5106-0.53031.65160.66110.7585-0.72841.94660.4809-0.75621.2181-0.28741.25924.436-27.07667.422
1331.0354-0.5385-1.45572.8472-2.54786.25341.21832.03170.3211-1.48-0.48-0.0499-0.27290.5037-0.54391.68190.67910.28411.39420.12610.701714.759-10.60667.704
1346.41033.84290.88498.3831-1.28123.18770.48250.51830.3839-0.45450.1741.0118-0.23050.0264-0.41951.10370.5697-0.15440.7360.28350.56465.757-16.88480.259
1352.49731.2479-1.54042.67640.63062.1606-0.0921-0.6975-1.2234-0.26060.0202-0.23430.54190.90430.24791.03670.6085-0.19171-0.09610.835335.366-44.60892.854
1368.68775.4662-0.58093.56910.13782.08630.07030.99130.6746-0.3597-0.272-0.0312-0.10160.0030.3321.0750.5364-0.04151.0004-0.02340.675735.52-34.43487.039
1372.1743-2.0059-0.12255.97130.65460.4990.41011.2990.0375-1.1484-0.3954-0.27450.54460.84980.08891.01050.4822-0.05451.12920.05190.5730.616-37.55885.712
1384.1692-1.197-4.00285.4497-0.10748.3227-0.2522-0.7002-0.52820.71770.41930.63930.00330.4779-0.14230.70430.2936-0.19760.39920.13160.60444.957-34.092112.501
1396.28565.6956-3.98529.3379-3.10889.510.5504-0.3647-0.5162-0.1298-0.4396-1.1134-0.50391.2766-0.16910.72070.2776-0.04690.48750.03050.558313.029-28.61999.909
1405.1650.173-2.14835.8151-6.10248.0122-0.04690.8495-0.6719-1.12010.0830.97310.7432-0.17060.01870.76110.163-0.21720.3359-0.04430.6522-1.77-41.008109.563
1415.51533.1267-4.16285.224-3.97744.1648-0.08010.1901-0.2245-0.8550.14820.54220.9425-0.2344-0.0050.78030.2158-0.12260.4107-0.00080.66141.4-40.428110.366
1421.759-1.1908-1.85633.54083.18913.34040.87320.42721.980.1508-0.35020.1124-1.3717-0.1234-0.19110.54970.0860.07080.5788-0.02830.801924.00227.078-23.682
1432.16312.2008-1.84662.2874-1.87171.59690.528-0.2724-0.21940.3872-0.5891-0.0553-0.6392-0.34470.00360.50680.16980.12950.59650.03050.596822.23210.826-14.546
1444.4784-1.44813.97273.86090.92495.9208-0.0095-0.1186-0.7940.0501-0.2510.3145-0.5888-1.51480.42470.58250.1540.04391.0496-0.13550.66217.9865.427-22.788
1452.00533.27561.6966.88160.7058.7317-0.41930.87250.717-0.303-0.0018-0.27970.42920.42720.50370.6020.3161-0.09941.1101-0.13990.9836.54917.378-32.489
1469.5001-1.69054.04229.5537-8.07019.1021-0.14650.11380.56880.10860.27280.6545-1.198-1.3137-0.22330.64060.2127-0.06920.7122-0.21120.91948.86224.196-22.549
1474.2603-0.8764-0.86610.18860.17270.1819-2.1404-2.669-1.06381.23030.88060.67251.0135-1.72351.21770.95850.20610.37111.6683-0.3161.14413.10413.619-6.877
1487.5024-1.81063.23018.96081.96646.8045-0.3382-1.45740.38710.18930.61960.2121-0.7772-0.3303-0.45130.39380.1462-0.01590.7308-0.10530.408818.6322.256-11.156
1496.72610.46157.79788.6764-0.71919.2147-1.4269-0.87752.424-0.07520.3950.8624-1.1514-1.63470.93530.88480.3922-0.0811.1525-0.21041.42818.65932.164-24.86
1505.0314-1.1650.01312.4482-2.18532.7997-0.5834-0.44590.13270.40220.69671.7517-0.8323-3.0249-0.23990.68830.1644-0.01781.3969-0.19311.1603-0.5917.922-23.692
1518.90086.6811-6.16628.6079-3.65917.80840.2412-0.8213-0.02440.9262-0.40280.09340.3489-1.22120.16550.41280.03130.09211.1387-0.34470.87327.4079.12-14.658
1529.14436.6529-4.48745.2592-4.11663.9752-0.48660.05950.3675-0.8280.309-0.46070.91270.79670.22050.64790.18920.0870.6691-0.09890.63718.1718.929-25.018
1533.65263.85790.25095.64692.78754.13840.30310.20521.38090.7724-0.73490.2109-1.2683-0.6140.48731.14050.02040.12540.45430.13870.802921.063-35.90349.222
1548.81782.20330.07551.34791.60123.11870.003-0.56461.27961.9151-0.19340.0623-1.73130.07570.16131.5835-0.0328-0.15760.5561-0.06450.576525.997-36.36863.182
1559.0844-7.10771.47226.7555-1.31726.8998-0.099-0.5470.54380.38520.15-0.7618-0.20410.1043-0.08070.9476-0.385-0.02330.57640.07810.569730.225-38.99555.164
1567.24450.95741.34833.8047-1.32536.3287-0.18970.01461.50361.9044-0.2258-0.1516-1.3766-0.53620.34481.2161-0.12150.18280.5049-0.05950.870517.937-31.98158.981
1573.3436-1.051-3.37972.92891.10188.40350.1722-0.3181-0.0880.3733-0.3066-0.8122-0.29020.50180.12710.6533-0.1482-0.12230.34410.17790.675436.934-54.25143.279
1583.02783.81492.46387.76956.56618.28210.54790.08870.20760.6334-0.1315-0.04440.80840.2067-0.22830.4199-0.035-0.01760.42610.15710.539634.182-61.90341.528
1593.4685-2.03992.45962.44520.13748.36590.1193-0.1103-0.7247-0.45550.1708-0.9490.8023-0.1786-0.30180.7967-0.10060.07930.34640.17620.800135.276-66.72826.767
1601.92080.0307-1.07675.51240.68778.2718-0.03710.4129-0.0603-0.4053-0.1276-0.6849-0.4486-0.5870.07060.4845-0.0896-0.01390.5020.19030.514232.773-58.82231.078
1613.97560.492-3.14942.4791-3.39446.25510.1727-0.5797-0.67471.30310.1605-0.21461.44430.9642-0.25831.1216-0.038-0.2180.5550.21980.524129.196-71.54560.923
1625.3129-3.6549-3.6525.02932.93753.9050.21340.37190.160.1947-0.48760.2128-0.233-0.43480.14310.8121-0.1501-0.03040.50150.06040.455315.944-56.28458.66
1637.6942-4.37171.54032.711-2.16297.99780.242-1.11670.66412.05480.3304-1.0011-0.69590.9632-0.56241.5039-0.3646-0.10811.0107-0.05470.662827.937-53.74374.345
1645.0309-4.908-0.33766.2591-0.65254.6851-0.3798-1.6624-0.22431.452-0.0899-0.08570.12140.880.41741.5819-0.28610.01130.79240.18020.525623.493-65.79274.341
1659.13531.2885-2.90352.8113-4.07886.17270.6201-1.24030.91580.6880.77691.29790.1835-1.7301-1.42081.1662-0.36680.19561.3701-0.12180.88897.6-62.0163.748
1666.3193-0.09631.79482.26390.9418.36220.5403-0.9639-0.70920.6833-0.4463-0.60210.5889-1.0147-0.02840.9084-0.4014-0.13610.8190.20620.55615.972-70.67763.442
1675.47735.0214.88026.48886.55486.646-0.1711-1.166-0.19550.96790.6786-0.61130.0570.5206-0.23332.2126-0.5665-1.07061.58750.46621.199129.799-70.92679.83
1683.9372-5.1468-5.50837.17846.83498.07580.9098-2.7627-0.3350.87640.07980.0360.0960.7617-0.99331.6015-0.5749-0.0361.16840.17350.793521.947-57.28681.1
1695.0585-3.535-1.54576.72094.61273.47770.9408-1.42350.66071.8981-0.9351.0060.4275-0.55810.1221.1228-0.4510.21430.8254-0.09690.758912.77-53.71170.1
1702.9379-1.40153.61729.72372.79156.76240.4426-0.3977-0.06320.9643-0.4486-0.74190.92620.5367-0.15270.8203-0.2163-0.07580.65860.10290.477927.208-62.54464.313
1716.7230.248-4.19196.6936-1.04032.8958-0.2590.4034-1.8170.15290.0921-0.02680.6626-1.28240.30411.0066-0.5291-0.17451.01290.14390.646-2.978-89.91951.914
1725.3262-4.50360.82429.0675-0.31842.02290.4151-1.67230.12530.2834-0.4578-0.0248-0.2506-0.25950.17950.9617-0.56650.0431.36930.07120.5988-3.748-79.88857.694
1737.4525-0.6982-3.59132.4851-0.34664.12810.0579-0.8865-1.22720.4531-0.220.1160.2779-0.94880.10850.9282-0.3819-0.06481.07620.21510.56181.604-83.10759.324
1747.16930.9194-6.76656.966-0.60426.59030.04021.1891-0.0616-1.00330.5322-0.5495-0.1474-0.6561-0.45630.7134-0.2122-0.10980.48520.06460.613126.987-78.77932.245
1758.9882-2.6511-2.17624.54076.5759.89220.61561.83160.691-1.6547-0.61461.2071-1.103-1.9602-0.27581.0320.0514-0.04970.96180.1410.730212.877-70.60743.376
1764.8143-5.1581-4.38397.97556.46115.3166-0.0947-0.421-0.15260.68670.2432-0.42210.47050.393-0.15790.5771-0.0884-0.10290.41110.0680.533131.769-83.12936.193
1774.2071-2.3935-5.53935.60122.92097.1624-0.3381-0.3755-0.3570.9494-0.1082-0.07930.70420.59230.36610.6403-0.1774-0.1770.59190.11410.60828.257-84.66736.578
1784.1584-2.1775-1.88737.87645.87528.06990.343-0.246-0.5029-0.23330.1149-0.4212-0.46990.4271-0.39040.3897-0.1780.04590.4330.09620.707-15.678-95.08128.333
1795.09921.4160.19669.2084-1.7422.38090.3649-0.3613-1.3466-0.1647-0.1548-0.89561.17470.7699-0.19520.8541-0.0897-0.09870.70230.15160.6026-5.876-101.44630.465
1807.8993-1.7444-1.83293.90680.9197.35070.067-1.0373-0.77290.75750.0620.15950.97720.529-0.14150.5586-0.1536-0.13030.6260.1770.5311-8.872-98.20632.962
1815.7968-3.3504-3.19844.9682.54072.9260.71110.21430.5553-0.3669-0.2223-0.6027-0.3594-0.1428-0.4610.3798-0.03110.12210.5540.12210.5104-13.602-88.86827.301
1826.7373-2.68190.43683.48750.14152.65240.0484-1.22120.55730.1575-0.56370.4724-0.1006-0.95080.4980.6984-0.23610.15450.9558-0.40780.6187-30.076-77.50941.422
1835.28252.8454-2.60946.223-0.56061.66090.16630.47510.3168-0.6703-0.5160.3558-0.8716-0.12780.25790.65860.05810.15810.8547-0.33220.6149-30.195-74.35631.15
1846.0749-0.3328-1.97842.0961-0.17172.7679-0.14-1.01280.2748-0.5202-0.82471.18880.1606-1.83620.96560.7509-0.0260.0831.2333-0.56330.9959-42.905-71.92330.76
1852.6691-1.8712-0.97682.77111.47423.8126-0.02570.5987-0.5158-0.0927-0.47340.8182-0.0909-1.07380.30310.58860.02180.20681.2692-0.32170.5771-37.572-78.75829.895
1867.8179-0.6863-4.76711.2226-0.52763.74980.34390.1975-0.0412-0.3269-0.75711.35650.208-1.04530.26960.5571-0.21760.17741.0515-0.38440.9965-37.486-79.66731.565
1875.40260.42124.97225.26573.96437.06850.28180.60590.89220.8308-0.12350.68250.1149-0.4223-0.01211.0069-0.12360.34360.62420.03180.71-9.894-62.84824.998
1889.66470.1843-2.66484.18632.50282.69560.4770.5698-1.1492-0.1938-0.83211.0911-0.3194-0.06080.29490.6137-0.15310.07870.6395-0.12480.4128-11.057-78.61116.53
1896.2777-4.424.21216.061-5.08999.31720.28220.5238-1.0450.30540.84020.0890.46470.4624-1.10950.3398-0.198-0.06510.82750.05420.66742.633-86.91523.134
1903.2071-2.7549-0.29024.77522.68283.1819-0.358-2.7347-1.52724.16890.01511.12631.6549-0.5440.36081.314-0.16710.14321.23990.38210.8736.714-74.38932.634
1915.51560.36681.30617.39755.70998.06490.04530.25330.4899-0.57050.7782-1.2902-1.41041.3221-0.93840.5883-0.1250.09750.67340.15840.89795.052-67.83522.964
1922.95073.93823.96367.7386.58586.4941-0.32641.412-0.6558-0.81860.3794-0.30740.49281.1096-0.04930.76810.02240.27390.85130.08830.853-2.646-77.4967.878
1938.40794.15744.38356.70356.42096.1914-0.94770.39230.2899-1.12160.7567-0.1259-1.00020.58230.22690.6740.00380.14020.67470.23470.5482-5.942-68.41112.468
1945.38073.33445.6892.62853.86726.2205-0.73830.73241.31050.15760.3011-2.5902-1.5581.27750.66511.1775-0.1952-0.35690.86560.23371.48676.421-59.57725.197
1954.9625.15485.035.43735.19975.15380.10980.52150.25430.17420.2784-1.2529-0.19531.7069-0.48780.589-0.08650.06910.63820.14450.986913.374-75.26523.743
1966.853-6.49861.36869.9117-2.79381.86520.33090.4524-0.6502-0.6029-0.8507-0.4629-0.12041.12420.54740.4302-0.03630.05430.69280.03530.66753.629-83.14815.799
1971.7897-2.5864-1.67835.90536.13177.8345-0.2413-0.60270.14490.1509-0.0953-0.21-0.48060.32490.25380.6459-0.20050.27050.4095-0.03160.6403-4.801-71.27726.246
1986.14942.6665-2.20177.448-4.72317.2957-0.29610.19010.08-0.0104-0.0222-0.1006-0.35370.56630.21110.66950.0511-0.04960.36870.03010.4003-12.042-57.002-6.661
1996.8989-1.4382-0.52586.3794-1.59125.16670.38750.23560.4093-0.4294-0.21890.8163-0.2488-1.0944-0.04940.57550.11150.020.7293-0.04410.729-32.886-62.65616.587
2002.60011.1331-2.58563.6107-1.13875.51860.50530.24091.72080.1962-0.25731.2994-0.808-1.4204-0.24780.78950.2604-0.07811.0001-0.35741.3879-38.768-56.15420.782
2017.4652.9791-0.82496.2753-3.45957.26710.55440.198-0.52130.272-0.2552-0.42130.96080.7778-0.36150.54610.242-0.12530.5073-0.17850.530226.006-96.108-26.989
2026.6105-3.6522-2.97362.52671.94392.58040.1166-0.1321-1.11040.3654-0.06361.1261.2146-0.8968-0.13730.73120.0424-0.11890.6022-0.08130.54815.225-100.677-30.218
2037.22380.9762-0.30393.3669-3.69676.37650.26870.6949-0.336-0.98170.0005-0.0220.6997-0.6664-0.2880.61990.2241-0.14340.6725-0.18810.3822.051-95.806-35.219
2043.8131-1.8454-1.97086.77451.55422.35430.30880.9356-0.39080.16210.12410.62540.8035-1.06890.05890.6658-0.0196-0.29570.4016-0.11790.622615.36-100.346-27.332
2056.16722.3134-0.29533.9727-0.88422.296-0.06870.8353-0.1739-0.1506-0.2159-0.3465-0.03180.40550.2210.46690.14580.07730.61970.03460.401336.78-82.529-30.59
2067.17993.42982.4315.05141.83331.0178-0.27521.29390.3381-0.5461-0.0707-0.0323-0.15120.82550.33740.64740.19090.12290.94710.19510.457529.905-76.417-38.954
2074.8881-4.78385.77026.7855-3.90878.0942-0.7254-0.3815-0.0530.8523-0.0726-0.89290.02210.64120.64820.6820.00580.12381.00220.29360.841450.561-73.403-23.864
2085.54660.1397-1.80263.37220.73030.79490.09090.16180.8735-0.0737-0.5615-0.8911-0.11321.20590.440.58960.03940.07021.26620.40520.759448.508-73.367-30.066
2098.75290.6201-5.99962.33950.73574.6748-0.1379-0.18750.5582-0.4009-0.411-1.21930.01071.3610.49260.55680.14430.13921.38610.48240.848252.43-80.09-31.058
2102.5196-2.80964.47533.3883-4.62548.728-0.6576-0.23751.8251-0.3152-0.1433-0.172-1.50220.24070.82820.9137-0.02950.08960.5367-0.0981.058617.375-60.753-24.577
2119.38656.9337-2.47785.1186-1.9361.5960.46540.4548-0.84840.0954-0.2572-1.1250.0718-0.0961-0.15290.52860.09710.10640.32510.00950.439521.288-78.227-15.269
2123.587-0.41524.76054.6015-1.41856.50470.3929-0.1559-1.1340.28870.68451.12910.054-0.5908-1.0340.36550.0904-0.00490.6766-0.00850.54587.644-86.68-22.072
2134.642.1959-5.04164.6062-5.33177.9104-0.15831.643-0.9638-3.77640.2204-0.33210.3815-0.38570.06170.99090.0921-0.09250.5686-0.31230.72714.171-76.712-30.578
2148.3521.76360.67092.0692-3.32927.15390.7559-0.23290.99690.92180.11241.5139-0.0039-0.8011-0.5430.88790.04390.15641.27740.07670.9853.256-66.309-33.714
2155.76191.9868-1.76526.2774-5.13964.20340.0606-0.06121.23720.77250.80760.7645-1.5221-1.3292-0.74560.53090.16340.17680.5247-0.03980.82795.147-68.004-20.473
2167.4834-4.78165.35315.7306-4.59884.3651-0.9254-2.76360.12381.21530.73720.50240.0302-1.74680.1140.75810.16540.15711.1421-0.05090.827811.887-77.343-6.871
2174.5367-0.72992.53382.2072-2.37833.2834-0.9695-0.32220.74730.84440.4396-0.1641-0.1543-0.7510.46510.7743-0.00210.07750.4783-0.16120.464715.994-68.191-11.29
2185.16055.17795.77899.06694.34157.784-1.833-0.05213.7673-0.6610.30331.2443-2.4089-0.76351.72721.21820.108-0.02140.71910.07771.12763.609-59.063-23.895
2197.9752-3.8715.22382.6099-4.31667.8539-0.11260.45120.19380.02570.51280.8735-0.4451-2.3224-0.40890.47910.22510.0480.8125-0.04760.8217-3.36-74.85-22.754
2204.16135.3177-0.06666.98520.18890.43650.7516-0.1020.10420.1947-0.64010.337-0.1262-0.2225-0.14420.48540.15450.09990.6310.01360.65216.494-82.804-14.808
2211.47551.371-0.17477.83180.32694.43120.00020.26350.1472-0.9703-0.26020.2322-0.24250.13920.12670.68050.21450.34090.4129-0.06920.545414.916-71.045-25.122
2227.3637-4.5151-5.03454.92225.81766.832-1.193-0.50460.1067-0.41251.1075-0.040.07931.23270.10071.1111-0.0539-0.04610.62060.05020.46926.64-53.8735.437
2237.7335-2.9857-4.00775.7896-2.64257.1006-0.4885-0.5327-0.289-0.76870.44030.1241-0.7115-0.09560.08440.8434-0.0053-0.05470.5095-0.04790.459621.934-57.98512.504
2245.51040.27174.29615.04432.79135.6193-0.6841-0.16590.21560.4299-0.09940.45750.1328-0.31910.82380.7691-0.04540.04220.3325-0.00570.392419.16-57.5084.609
2255.2059-3.3084-6.90625.33583.02059.77280.5045-2.1198-0.7043-0.0702-0.2649-1.3235-0.2041.7832-0.20220.5018-0.2515-0.13470.82250.03051.100646.204-61.533-13.09
2265.47695.3159-6.70839.168-4.2479.625-0.7397-0.9046-1.47250.2631-0.3649-0.88680.59541.04190.96830.7917-0.13320.06610.88540.14210.675941.561-67.403-13.412
2277.44775.5555-5.04646.1963-4.59435.3093-0.3979-0.03921.3547-0.5370.61570.0295-0.20610.3619-0.15610.7313-0.11720.07490.7778-0.06291.070942.323-56.716-17.338
2286.4726-0.7056-2.26192.615-0.49236.52810.5898-0.56141.7888-0.7991-0.1959-0.32-0.56461.4529-0.39320.8185-0.27750.02281.08750.4251.36951.034-55.156-21.164
2298.2825-2.3642-2.03295.66340.39064.40650.29750.1050.67770.1502-0.2907-0.9401-0.82921.3305-0.11530.8274-0.3044-0.20.94650.28830.843244.731-55.548-15.197
2301.97893.1866-0.20345.27080.3322.54760.014-0.3801-1.1843-0.0076-0.42631.06140.2674-0.31550.31230.38090.09760.09010.5498-0.08671.5304-41.499-54.839-25.002
2311.7174-1.1259-1.88761.87131.02073.49260.1596-0.2537-1.14670.8703-0.96210.48790.8237-0.92170.69390.7579-0.27860.02960.8416-0.21481.5239-49.783-62.1-27.375
2320.7189-0.6053-0.44751.4831-0.29314.5566-0.05380.481-0.9169-0.1302-0.43870.73010.7715-0.80160.50330.45020.16640.13450.8738-0.23262.2549-50.474-54.406-27.616
2330.13810.00320.56820.00450.00972.3064-0.1482-0.1517-0.9590.2085-0.24281.0850.689-0.57720.30350.549-0.09510.23930.5815-0.24291.3868-43.176-48.411-23.98
2347.8671-3.3772-0.46722.6056-1.18394.93090.21040.69070.1276-0.8127-0.35710.8294-0.5974-0.02820.11330.63040.1202-0.1670.3278-0.11420.7262-26.768-38.442-39.645
2355.4018-0.685-0.61666.08641.9526.68450.1251-0.42390.52310.1732-0.2640.018-1.0992-0.18820.12230.4812-0.02510.02410.2720.0330.6048-26.186-34.916-29.771
2369.1518-3.73512.62729.7067-1.3556.7250.00370.22140.73590.5235-0.4261-1.0248-1.10530.99170.27230.7641-0.1662-0.01850.54950.11140.6775-13.196-33.469-30.309
2372.7419-2.0277-4.64299.26310.8848.8265-0.2595-0.7927-0.76710.1502-0.243-0.12790.06191.3080.53620.41970.06670.01180.5351-0.02410.3481-19.181-40.38-29.775
2385.96856.82133.51447.87973.46675.8147-0.6126-0.29011.9454-0.3749-0.4341-0.1192-1.4733-1.39621.00721.39310.423-0.04740.621-0.12470.7386-46.016-22.196-24.096
2395.08141.77280.70595.324-1.17154.29760.22050.1998-1.84390.2819-0.47350.3196-0.0605-1.23890.3250.49890.20260.16690.9325-0.13991.0313-46.98-39.599-13.952
2407.0835-3.35092.67163.4104-0.35822.3204-0.34721.2474-0.8462-1.0662-0.90380.34630.6773-0.23941.30970.90410.35860.14741.4668-0.30681.714-61.889-36.765-26.426
2419.0203-3.29232.81369.442-2.72513.30120.037-0.6443-0.45050.7578-0.24381.4068-0.9152-1.96380.07550.80210.27840.18181.1822-0.33961.1079-56.85-29.717-13.467
2428.2699-1.91095.40835.2954-2.15777.4252-0.9711-0.4151.4191-0.0328-0.13250.8085-1.5406-2.16640.94290.83280.3994-0.05271.1244-0.29021.1417-54.73-22.219-16.653
2436.7420.1176-2.62257.0209-1.91753.0403-0.3486-1.07360.80860.56491.2510.7662-0.8976-1.6638-0.85350.82780.42920.0921.9861-0.33211.6799-68.866-33.508-18.868
2446.9303-2.05050.06375.44791.91714.37490.04150.2502-1.1186-0.9239-0.49831.056-0.2853-0.55510.39120.57880.48310.10850.9431-0.22341.08-54.019-34.7-18.566
2457.9106-4.3939-4.16346.74734.16793.31980.4091-0.1072-0.2496-0.0834-0.3068-0.20060.042-0.177-0.10370.51240.0281-0.06730.44050.01190.4255-42.479-13.0126.62
2466.86890.4353-1.574.03850.72173.2129-0.0786-0.86061.24170.30080.3184-0.7912-0.60210.4164-0.15370.83680.0551-0.10540.4916-0.14170.9908-18.578-19.371-19.248
2478.39755.33960.84988.74710.33393.99110.4770.31870.39280.49390.0302-0.0121-0.88590.4288-0.50420.71490.13360.15810.61060.09420.452357.9576.451-44.664
2486.2199-5.38495.01534.655-4.3434.0534-0.50740.10492.29410.8255-0.1658-1.5595-1.62841.28210.5591.2923-0.3059-0.03661.20950.07381.17966.29420.381-40.622
2496.8949-1.1202-4.35556.2416-0.56459.04380.67391.64671.1028-0.8428-0.6106-0.2974-1.343-0.1635-0.1420.93390.04040.15511.00960.23120.569358.45112.454-57.514
2504.09821.0683-4.67180.7651-1.93327.68420.2710.11140.3116-0.1924-0.2958-0.1165-0.77130.24220.04110.67730.21650.10580.69040.12980.649254.2785.859-46.957
2514.46083.7777-4.69443.6304-4.29885.20320.07571.49180.4098-0.11350.76261.003-0.6225-1.8124-1.04960.8670.1989-0.0610.85590.09950.730337.55-5.424-44.711
2525.99121.7141-4.60092.2759-2.72867.55840.2740.8005-0.2588-0.2603-0.4070.3870.59430.49430.16730.64350.1681-0.03330.65980.1530.643844.099-14.046-40.21
2532.1645-4.55582.28359.5802-4.78192.42070.81760.75-1.01550.25540.1141-0.32570.60320.3421-0.94690.58850.14120.04420.60690.03970.791346.42-21.772-24.612
2546.62882.5826-2.70855.9648-1.08522.60190.0225-0.1472-0.35460.28490.50940.87560.2275-0.5745-0.64060.46090.1485-0.0590.65010.19770.62539.223-16.255-28.554
2559.6655-1.8318-6.53513.57471.68144.44320.0056-0.9684-0.26580.126-0.2120.43420.24210.37780.12660.30970.049-0.04780.5810.01250.492743.777-11.519-29.611
2569.9265.0279-2.50159.6292-3.1336.7504-0.261.56060.00270.17460.25380.25180.195-0.7679-0.03920.81480.32-0.19890.78310.06360.585850.977-22.044-60.064
2574.96745.6681-4.3836.4795-4.97373.8530.4378-0.6161-0.70921.0248-0.7345-1.194-0.29510.33530.24110.72230.273-0.03941.05260.15450.52964.234-12.373-51.938
2585.3868-5.34595.84545.3053-5.80576.34410.6510.44790.89630.32880.55330.3947-1.2721-0.5139-1.1270.8096-0.07150.06751.70570.38580.769369.0572.335-59.96
2596.75126.2856.32385.85025.88995.9327-0.9054-0.33430.2538-1.191.23071.2205-1.8670.1087-0.32240.88530.14540.06340.84130.12850.749859.377-1.773-68.318
2603.57631.4211-5.14633.5216-1.36057.7984-0.43520.90170.5831-1.09230.14410.44720.5957-0.59190.2681.0062-0.0034-0.09371.2779-0.06990.830649.666-9.059-75.564
2615.45515.5365.18157.94862.06099.7751-0.77311.2792-0.8461-0.50390.3555-0.63591.43481.28130.40710.9450.38410.1961.12010.11360.674761.361-15.524-70.987
2625.36992.47842.2382.98012.37561.9202-0.29210.0966-0.2732-0.02490.3381-2.18922.27373.5205-0.03420.99840.4928-0.00571.46030.0750.995274.167-15.067-58.544
2636.10940.23346.0294.2917-0.14446.0320.92541.3385-1.6152-0.9644-0.0409-0.31860.64441.8243-0.82640.97490.48610.01771.3792-0.12620.755264.525-22.592-60.471
2641.8229-1.25721.67482.8278-2.88293.0607-0.51550.7572-0.0202-1.45110.0594-0.27093.28481.96720.41561.73390.15620.03351.3172-0.11660.884553.54-20.043-78.043
2654.43331.26723.887.29270.26893.65210.28221.7601-0.3587-1.62490.5738-0.4505-0.80482.3037-0.69251.08560.0670.12961.4586-0.05460.698264.803-6.785-76.479
2669.07457.4892.64097.8765-0.08838.6414-0.59510.41360.0938-0.44960.333-0.01720.10680.4610.35720.74920.27660.04940.9461-0.01480.571561.495-10.034-62.488
Refinement TLS group
IDRefine-IDRefine TLS-IDSelection detailsAuth asym-IDAuth seq-ID
1X-RAY DIFFRACTION1chain '0' and (resid 20 through 75 )020 - 75
2X-RAY DIFFRACTION2chain '0' and (resid 76 through 154 )076 - 154
3X-RAY DIFFRACTION3chain '0' and (resid 155 through 214 )0155 - 214
4X-RAY DIFFRACTION4chain '1' and (resid 24 through 51 )124 - 51
5X-RAY DIFFRACTION5chain '1' and (resid 52 through 69 )152 - 69
6X-RAY DIFFRACTION6chain '1' and (resid 70 through 91 )170 - 91
7X-RAY DIFFRACTION7chain '1' and (resid 92 through 124 )192 - 124
8X-RAY DIFFRACTION8chain '1' and (resid 125 through 140 )1125 - 140
9X-RAY DIFFRACTION9chain '1' and (resid 141 through 155 )1141 - 155
10X-RAY DIFFRACTION10chain '1' and (resid 156 through 172 )1156 - 172
11X-RAY DIFFRACTION11chain '1' and (resid 173 through 214 )1173 - 214
12X-RAY DIFFRACTION12chain '1' and (resid 215 through 224 )1215 - 224
13X-RAY DIFFRACTION13chain '2' and (resid 40 through 49 )240 - 49
14X-RAY DIFFRACTION14chain '2' and (resid 50 through 70 )250 - 70
15X-RAY DIFFRACTION15chain '2' and (resid 71 through 80 )271 - 80
16X-RAY DIFFRACTION16chain '2' and (resid 81 through 111 )281 - 111
17X-RAY DIFFRACTION17chain '2' and (resid 112 through 128 )2112 - 128
18X-RAY DIFFRACTION18chain '2' and (resid 129 through 138 )2129 - 138
19X-RAY DIFFRACTION19chain '2' and (resid 139 through 179 )2139 - 179
20X-RAY DIFFRACTION20chain '3' and (resid 20 through 75 )320 - 75
21X-RAY DIFFRACTION21chain '3' and (resid 76 through 144 )376 - 144
22X-RAY DIFFRACTION22chain '3' and (resid 145 through 185 )3145 - 185
23X-RAY DIFFRACTION23chain '3' and (resid 186 through 214 )3186 - 214
24X-RAY DIFFRACTION24chain '4' and (resid 24 through 105 )424 - 105
25X-RAY DIFFRACTION25chain '4' and (resid 106 through 140 )4106 - 140
26X-RAY DIFFRACTION26chain '4' and (resid 141 through 224 )4141 - 224
27X-RAY DIFFRACTION27chain '5' and (resid 39 through 49 )539 - 49
28X-RAY DIFFRACTION28chain '5' and (resid 50 through 66 )550 - 66
29X-RAY DIFFRACTION29chain '5' and (resid 67 through 76 )567 - 76
30X-RAY DIFFRACTION30chain '5' and (resid 77 through 114 )577 - 114
31X-RAY DIFFRACTION31chain '5' and (resid 115 through 126 )5115 - 126
32X-RAY DIFFRACTION32chain '5' and (resid 127 through 140 )5127 - 140
33X-RAY DIFFRACTION33chain '5' and (resid 141 through 166 )5141 - 166
34X-RAY DIFFRACTION34chain '5' and (resid 167 through 179 )5167 - 179
35X-RAY DIFFRACTION35chain '6' and (resid 20 through 66 )620 - 66
36X-RAY DIFFRACTION36chain '6' and (resid 67 through 100 )667 - 100
37X-RAY DIFFRACTION37chain '6' and (resid 101 through 144 )6101 - 144
38X-RAY DIFFRACTION38chain '6' and (resid 145 through 185 )6145 - 185
39X-RAY DIFFRACTION39chain '6' and (resid 186 through 214 )6186 - 214
40X-RAY DIFFRACTION40chain '7' and (resid 24 through 51 )724 - 51
41X-RAY DIFFRACTION41chain '7' and (resid 52 through 68 )752 - 68
42X-RAY DIFFRACTION42chain '7' and (resid 69 through 109 )769 - 109
43X-RAY DIFFRACTION43chain '7' and (resid 110 through 155 )7110 - 155
44X-RAY DIFFRACTION44chain '7' and (resid 156 through 204 )7156 - 204
45X-RAY DIFFRACTION45chain '7' and (resid 205 through 224 )7205 - 224
46X-RAY DIFFRACTION46chain '8' and (resid 40 through 70 )840 - 70
47X-RAY DIFFRACTION47chain '8' and (resid 71 through 114 )871 - 114
48X-RAY DIFFRACTION48chain '8' and (resid 115 through 140 )8115 - 140
49X-RAY DIFFRACTION49chain '8' and (resid 141 through 179 )8141 - 179
50X-RAY DIFFRACTION50chain '9' and (resid 20 through 66 )920 - 66
51X-RAY DIFFRACTION51chain '9' and (resid 67 through 110 )967 - 110
52X-RAY DIFFRACTION52chain '9' and (resid 111 through 178 )9111 - 178
53X-RAY DIFFRACTION53chain '9' and (resid 179 through 212 )9179 - 212
54X-RAY DIFFRACTION54chain 'A' and (resid 24 through 40 )A24 - 40
55X-RAY DIFFRACTION55chain 'A' and (resid 41 through 51 )A41 - 51
56X-RAY DIFFRACTION56chain 'A' and (resid 52 through 69 )A52 - 69
57X-RAY DIFFRACTION57chain 'A' and (resid 70 through 80 )A70 - 80
58X-RAY DIFFRACTION58chain 'A' and (resid 81 through 91 )A81 - 91
59X-RAY DIFFRACTION59chain 'A' and (resid 92 through 109 )A92 - 109
60X-RAY DIFFRACTION60chain 'A' and (resid 110 through 133 )A110 - 133
61X-RAY DIFFRACTION61chain 'A' and (resid 134 through 155 )A134 - 155
62X-RAY DIFFRACTION62chain 'A' and (resid 156 through 170 )A156 - 170
63X-RAY DIFFRACTION63chain 'A' and (resid 171 through 181 )A171 - 181
64X-RAY DIFFRACTION64chain 'A' and (resid 182 through 195 )A182 - 195
65X-RAY DIFFRACTION65chain 'A' and (resid 196 through 205 )A196 - 205
66X-RAY DIFFRACTION66chain 'A' and (resid 206 through 224 )A206 - 224
67X-RAY DIFFRACTION67chain 'B' and (resid 24 through 124 )B24 - 124
68X-RAY DIFFRACTION68chain 'B' and (resid 125 through 224 )B125 - 224
69X-RAY DIFFRACTION69chain 'C' and (resid 20 through 50 )C20 - 50
70X-RAY DIFFRACTION70chain 'C' and (resid 51 through 75 )C51 - 75
71X-RAY DIFFRACTION71chain 'C' and (resid 76 through 122 )C76 - 122
72X-RAY DIFFRACTION72chain 'C' and (resid 123 through 156 )C123 - 156
73X-RAY DIFFRACTION73chain 'C' and (resid 157 through 214 )C157 - 214
74X-RAY DIFFRACTION74chain 'D' and (resid 40 through 49 )D40 - 49
75X-RAY DIFFRACTION75chain 'D' and (resid 50 through 65 )D50 - 65
76X-RAY DIFFRACTION76chain 'D' and (resid 66 through 75 )D66 - 75
77X-RAY DIFFRACTION77chain 'D' and (resid 76 through 85 )D76 - 85
78X-RAY DIFFRACTION78chain 'D' and (resid 86 through 102 )D86 - 102
79X-RAY DIFFRACTION79chain 'D' and (resid 103 through 114 )D103 - 114
80X-RAY DIFFRACTION80chain 'D' and (resid 115 through 128 )D115 - 128
81X-RAY DIFFRACTION81chain 'D' and (resid 129 through 138 )D129 - 138
82X-RAY DIFFRACTION82chain 'D' and (resid 139 through 165 )D139 - 165
83X-RAY DIFFRACTION83chain 'D' and (resid 166 through 179 )D166 - 179
84X-RAY DIFFRACTION84chain 'E' and (resid 22 through 49 )E22 - 49
85X-RAY DIFFRACTION85chain 'E' and (resid 50 through 75 )E50 - 75
86X-RAY DIFFRACTION86chain 'E' and (resid 76 through 93 )E76 - 93
87X-RAY DIFFRACTION87chain 'E' and (resid 94 through 123 )E94 - 123
88X-RAY DIFFRACTION88chain 'E' and (resid 124 through 173 )E124 - 173
89X-RAY DIFFRACTION89chain 'E' and (resid 174 through 186 )E174 - 186
90X-RAY DIFFRACTION90chain 'E' and (resid 187 through 214 )E187 - 214
91X-RAY DIFFRACTION91chain 'F' and (resid 24 through 51 )F24 - 51
92X-RAY DIFFRACTION92chain 'F' and (resid 52 through 80 )F52 - 80
93X-RAY DIFFRACTION93chain 'F' and (resid 81 through 109 )F81 - 109
94X-RAY DIFFRACTION94chain 'F' and (resid 110 through 155 )F110 - 155
95X-RAY DIFFRACTION95chain 'F' and (resid 156 through 172 )F156 - 172
96X-RAY DIFFRACTION96chain 'F' and (resid 173 through 205 )F173 - 205
97X-RAY DIFFRACTION97chain 'F' and (resid 206 through 224 )F206 - 224
98X-RAY DIFFRACTION98chain 'G' and (resid 40 through 49 )G40 - 49
99X-RAY DIFFRACTION99chain 'G' and (resid 50 through 65 )G50 - 65
100X-RAY DIFFRACTION100chain 'G' and (resid 66 through 75 )G66 - 75
101X-RAY DIFFRACTION101chain 'G' and (resid 76 through 80 )G76 - 80
102X-RAY DIFFRACTION102chain 'G' and (resid 81 through 101 )G81 - 101
103X-RAY DIFFRACTION103chain 'G' and (resid 102 through 114 )G102 - 114
104X-RAY DIFFRACTION104chain 'G' and (resid 115 through 126 )G115 - 126
105X-RAY DIFFRACTION105chain 'G' and (resid 127 through 139 )G127 - 139
106X-RAY DIFFRACTION106chain 'G' and (resid 140 through 154 )G140 - 154
107X-RAY DIFFRACTION107chain 'G' and (resid 155 through 179 )G155 - 179
108X-RAY DIFFRACTION108chain 'H' and (resid 20 through 39 )H20 - 39
109X-RAY DIFFRACTION109chain 'H' and (resid 40 through 50 )H40 - 50
110X-RAY DIFFRACTION110chain 'H' and (resid 51 through 75 )H51 - 75
111X-RAY DIFFRACTION111chain 'H' and (resid 76 through 92 )H76 - 92
112X-RAY DIFFRACTION112chain 'H' and (resid 93 through 110 )H93 - 110
113X-RAY DIFFRACTION113chain 'H' and (resid 111 through 132 )H111 - 132
114X-RAY DIFFRACTION114chain 'H' and (resid 133 through 144 )H133 - 144
115X-RAY DIFFRACTION115chain 'H' and (resid 145 through 163 )H145 - 163
116X-RAY DIFFRACTION116chain 'H' and (resid 164 through 173 )H164 - 173
117X-RAY DIFFRACTION117chain 'H' and (resid 174 through 204 )H174 - 204
118X-RAY DIFFRACTION118chain 'H' and (resid 205 through 214 )H205 - 214
119X-RAY DIFFRACTION119chain 'I' and (resid 24 through 51 )I24 - 51
120X-RAY DIFFRACTION120chain 'I' and (resid 52 through 69 )I52 - 69
121X-RAY DIFFRACTION121chain 'I' and (resid 70 through 91 )I70 - 91
122X-RAY DIFFRACTION122chain 'I' and (resid 92 through 124 )I92 - 124
123X-RAY DIFFRACTION123chain 'I' and (resid 125 through 155 )I125 - 155
124X-RAY DIFFRACTION124chain 'I' and (resid 156 through 170 )I156 - 170
125X-RAY DIFFRACTION125chain 'I' and (resid 171 through 205 )I171 - 205
126X-RAY DIFFRACTION126chain 'I' and (resid 206 through 224 )I206 - 224
127X-RAY DIFFRACTION127chain 'J' and (resid 40 through 49 )J40 - 49
128X-RAY DIFFRACTION128chain 'J' and (resid 50 through 65 )J50 - 65
129X-RAY DIFFRACTION129chain 'J' and (resid 66 through 80 )J66 - 80
130X-RAY DIFFRACTION130chain 'J' and (resid 81 through 113 )J81 - 113
131X-RAY DIFFRACTION131chain 'J' and (resid 114 through 126 )J114 - 126
132X-RAY DIFFRACTION132chain 'J' and (resid 127 through 138 )J127 - 138
133X-RAY DIFFRACTION133chain 'J' and (resid 139 through 165 )J139 - 165
134X-RAY DIFFRACTION134chain 'J' and (resid 166 through 179 )J166 - 179
135X-RAY DIFFRACTION135chain 'K' and (resid 20 through 50 )K20 - 50
136X-RAY DIFFRACTION136chain 'K' and (resid 51 through 75 )K51 - 75
137X-RAY DIFFRACTION137chain 'K' and (resid 76 through 110 )K76 - 110
138X-RAY DIFFRACTION138chain 'K' and (resid 111 through 132 )K111 - 132
139X-RAY DIFFRACTION139chain 'K' and (resid 133 through 156 )K133 - 156
140X-RAY DIFFRACTION140chain 'K' and (resid 157 through 178 )K157 - 178
141X-RAY DIFFRACTION141chain 'K' and (resid 179 through 214 )K179 - 214
142X-RAY DIFFRACTION142chain 'L' and (resid 40 through 49 )L40 - 49
143X-RAY DIFFRACTION143chain 'L' and (resid 50 through 66 )L50 - 66
144X-RAY DIFFRACTION144chain 'L' and (resid 67 through 76 )L67 - 76
145X-RAY DIFFRACTION145chain 'L' and (resid 77 through 85 )L77 - 85
146X-RAY DIFFRACTION146chain 'L' and (resid 86 through 101 )L86 - 101
147X-RAY DIFFRACTION147chain 'L' and (resid 102 through 114 )L102 - 114
148X-RAY DIFFRACTION148chain 'L' and (resid 115 through 126 )L115 - 126
149X-RAY DIFFRACTION149chain 'L' and (resid 127 through 138 )L127 - 138
150X-RAY DIFFRACTION150chain 'L' and (resid 139 through 154 )L139 - 154
151X-RAY DIFFRACTION151chain 'L' and (resid 155 through 166 )L155 - 166
152X-RAY DIFFRACTION152chain 'L' and (resid 167 through 179 )L167 - 179
153X-RAY DIFFRACTION153chain 'M' and (resid 24 through 51 )M24 - 51
154X-RAY DIFFRACTION154chain 'M' and (resid 52 through 69 )M52 - 69
155X-RAY DIFFRACTION155chain 'M' and (resid 70 through 91 )M70 - 91
156X-RAY DIFFRACTION156chain 'M' and (resid 92 through 109 )M92 - 109
157X-RAY DIFFRACTION157chain 'M' and (resid 110 through 155 )M110 - 155
158X-RAY DIFFRACTION158chain 'M' and (resid 156 through 170 )M156 - 170
159X-RAY DIFFRACTION159chain 'M' and (resid 171 through 195 )M171 - 195
160X-RAY DIFFRACTION160chain 'M' and (resid 196 through 224 )M196 - 224
161X-RAY DIFFRACTION161chain 'N' and (resid 40 through 49 )N40 - 49
162X-RAY DIFFRACTION162chain 'N' and (resid 50 through 70 )N50 - 70
163X-RAY DIFFRACTION163chain 'N' and (resid 71 through 85 )N71 - 85
164X-RAY DIFFRACTION164chain 'N' and (resid 86 through 102 )N86 - 102
165X-RAY DIFFRACTION165chain 'N' and (resid 103 through 114 )N103 - 114
166X-RAY DIFFRACTION166chain 'N' and (resid 115 through 128 )N115 - 128
167X-RAY DIFFRACTION167chain 'N' and (resid 129 through 139 )N129 - 139
168X-RAY DIFFRACTION168chain 'N' and (resid 140 through 154 )N140 - 154
169X-RAY DIFFRACTION169chain 'N' and (resid 155 through 166 )N155 - 166
170X-RAY DIFFRACTION170chain 'N' and (resid 167 through 179 )N167 - 179
171X-RAY DIFFRACTION171chain 'O' and (resid 20 through 50 )O20 - 50
172X-RAY DIFFRACTION172chain 'O' and (resid 51 through 75 )O51 - 75
173X-RAY DIFFRACTION173chain 'O' and (resid 76 through 110 )O76 - 110
174X-RAY DIFFRACTION174chain 'O' and (resid 111 through 132 )O111 - 132
175X-RAY DIFFRACTION175chain 'O' and (resid 133 through 144 )O133 - 144
176X-RAY DIFFRACTION176chain 'O' and (resid 145 through 194 )O145 - 194
177X-RAY DIFFRACTION177chain 'O' and (resid 195 through 215 )O195 - 215
178X-RAY DIFFRACTION178chain 'P' and (resid 24 through 40 )P24 - 40
179X-RAY DIFFRACTION179chain 'P' and (resid 41 through 69 )P41 - 69
180X-RAY DIFFRACTION180chain 'P' and (resid 70 through 105 )P70 - 105
181X-RAY DIFFRACTION181chain 'P' and (resid 106 through 124 )P106 - 124
182X-RAY DIFFRACTION182chain 'P' and (resid 125 through 155 )P125 - 155
183X-RAY DIFFRACTION183chain 'P' and (resid 156 through 172 )P156 - 172
184X-RAY DIFFRACTION184chain 'P' and (resid 173 through 195 )P173 - 195
185X-RAY DIFFRACTION185chain 'P' and (resid 196 through 205 )P196 - 205
186X-RAY DIFFRACTION186chain 'P' and (resid 206 through 224 )P206 - 224
187X-RAY DIFFRACTION187chain 'Q' and (resid 40 through 49 )Q40 - 49
188X-RAY DIFFRACTION188chain 'Q' and (resid 50 through 65 )Q50 - 65
189X-RAY DIFFRACTION189chain 'Q' and (resid 66 through 75 )Q66 - 75
190X-RAY DIFFRACTION190chain 'Q' and (resid 76 through 84 )Q76 - 84
191X-RAY DIFFRACTION191chain 'Q' and (resid 85 through 102 )Q85 - 102
192X-RAY DIFFRACTION192chain 'Q' and (resid 103 through 114 )Q103 - 114
193X-RAY DIFFRACTION193chain 'Q' and (resid 115 through 126 )Q115 - 126
194X-RAY DIFFRACTION194chain 'Q' and (resid 127 through 138 )Q127 - 138
195X-RAY DIFFRACTION195chain 'Q' and (resid 139 through 154 )Q139 - 154
196X-RAY DIFFRACTION196chain 'Q' and (resid 155 through 166 )Q155 - 166
197X-RAY DIFFRACTION197chain 'Q' and (resid 167 through 179 )Q167 - 179
198X-RAY DIFFRACTION198chain 'R' and (resid 20 through 110 )R20 - 110
199X-RAY DIFFRACTION199chain 'R' and (resid 111 through 163 )R111 - 163
200X-RAY DIFFRACTION200chain 'R' and (resid 164 through 214 )R164 - 214
201X-RAY DIFFRACTION201chain 'S' and (resid 24 through 43 )S24 - 43
202X-RAY DIFFRACTION202chain 'S' and (resid 44 through 69 )S44 - 69
203X-RAY DIFFRACTION203chain 'S' and (resid 70 through 89 )S70 - 89
204X-RAY DIFFRACTION204chain 'S' and (resid 90 through 105 )S90 - 105
205X-RAY DIFFRACTION205chain 'S' and (resid 106 through 138 )S106 - 138
206X-RAY DIFFRACTION206chain 'S' and (resid 139 through 163 )S139 - 163
207X-RAY DIFFRACTION207chain 'S' and (resid 164 through 181 )S164 - 181
208X-RAY DIFFRACTION208chain 'S' and (resid 182 through 209 )S182 - 209
209X-RAY DIFFRACTION209chain 'S' and (resid 210 through 224 )S210 - 224
210X-RAY DIFFRACTION210chain 'T' and (resid 38 through 49 )T38 - 49
211X-RAY DIFFRACTION211chain 'T' and (resid 50 through 65 )T50 - 65
212X-RAY DIFFRACTION212chain 'T' and (resid 66 through 75 )T66 - 75
213X-RAY DIFFRACTION213chain 'T' and (resid 76 through 80 )T76 - 80
214X-RAY DIFFRACTION214chain 'T' and (resid 81 through 87 )T81 - 87
215X-RAY DIFFRACTION215chain 'T' and (resid 88 through 101 )T88 - 101
216X-RAY DIFFRACTION216chain 'T' and (resid 102 through 114 )T102 - 114
217X-RAY DIFFRACTION217chain 'T' and (resid 115 through 126 )T115 - 126
218X-RAY DIFFRACTION218chain 'T' and (resid 127 through 138 )T127 - 138
219X-RAY DIFFRACTION219chain 'T' and (resid 139 through 154 )T139 - 154
220X-RAY DIFFRACTION220chain 'T' and (resid 155 through 166 )T155 - 166
221X-RAY DIFFRACTION221chain 'T' and (resid 167 through 179 )T167 - 179
222X-RAY DIFFRACTION222chain 'U' and (resid 20 through 39 )U20 - 39
223X-RAY DIFFRACTION223chain 'U' and (resid 40 through 75 )U40 - 75
224X-RAY DIFFRACTION224chain 'U' and (resid 76 through 110 )U76 - 110
225X-RAY DIFFRACTION225chain 'U' and (resid 111 through 123 )U111 - 123
226X-RAY DIFFRACTION226chain 'U' and (resid 124 through 144 )U124 - 144
227X-RAY DIFFRACTION227chain 'U' and (resid 145 through 163 )U145 - 163
228X-RAY DIFFRACTION228chain 'U' and (resid 164 through 194 )U164 - 194
229X-RAY DIFFRACTION229chain 'U' and (resid 195 through 214 )U195 - 214
230X-RAY DIFFRACTION230chain 'V' and (resid 24 through 40 )V24 - 40
231X-RAY DIFFRACTION231chain 'V' and (resid 41 through 80 )V41 - 80
232X-RAY DIFFRACTION232chain 'V' and (resid 81 through 105 )V81 - 105
233X-RAY DIFFRACTION233chain 'V' and (resid 106 through 124 )V106 - 124
234X-RAY DIFFRACTION234chain 'V' and (resid 125 through 155 )V125 - 155
235X-RAY DIFFRACTION235chain 'V' and (resid 156 through 172 )V156 - 172
236X-RAY DIFFRACTION236chain 'V' and (resid 173 through 195 )V173 - 195
237X-RAY DIFFRACTION237chain 'V' and (resid 196 through 224 )V196 - 224
238X-RAY DIFFRACTION238chain 'W' and (resid 40 through 49 )W40 - 49
239X-RAY DIFFRACTION239chain 'W' and (resid 50 through 70 )W50 - 70
240X-RAY DIFFRACTION240chain 'W' and (resid 71 through 85 )W71 - 85
241X-RAY DIFFRACTION241chain 'W' and (resid 86 through 114 )W86 - 114
242X-RAY DIFFRACTION242chain 'W' and (resid 115 through 138 )W115 - 138
243X-RAY DIFFRACTION243chain 'W' and (resid 139 through 155 )W139 - 155
244X-RAY DIFFRACTION244chain 'W' and (resid 156 through 179 )W156 - 179
245X-RAY DIFFRACTION245chain 'X' and (resid 20 through 110 )X20 - 110
246X-RAY DIFFRACTION246chain 'X' and (resid 111 through 216 )X111 - 216
247X-RAY DIFFRACTION247chain 'Y' and (resid 24 through 40 )Y24 - 40
248X-RAY DIFFRACTION248chain 'Y' and (resid 41 through 51 )Y41 - 51
249X-RAY DIFFRACTION249chain 'Y' and (resid 52 through 69 )Y52 - 69
250X-RAY DIFFRACTION250chain 'Y' and (resid 70 through 133 )Y70 - 133
251X-RAY DIFFRACTION251chain 'Y' and (resid 134 through 155 )Y134 - 155
252X-RAY DIFFRACTION252chain 'Y' and (resid 156 through 170 )Y156 - 170
253X-RAY DIFFRACTION253chain 'Y' and (resid 171 through 181 )Y171 - 181
254X-RAY DIFFRACTION254chain 'Y' and (resid 182 through 205 )Y182 - 205
255X-RAY DIFFRACTION255chain 'Y' and (resid 206 through 224 )Y206 - 224
256X-RAY DIFFRACTION256chain 'Z' and (resid 40 through 49 )Z40 - 49
257X-RAY DIFFRACTION257chain 'Z' and (resid 50 through 65 )Z50 - 65
258X-RAY DIFFRACTION258chain 'Z' and (resid 66 through 70 )Z66 - 70
259X-RAY DIFFRACTION259chain 'Z' and (resid 71 through 80 )Z71 - 80
260X-RAY DIFFRACTION260chain 'Z' and (resid 81 through 87 )Z81 - 87
261X-RAY DIFFRACTION261chain 'Z' and (resid 88 through 102 )Z88 - 102
262X-RAY DIFFRACTION262chain 'Z' and (resid 103 through 114 )Z103 - 114
263X-RAY DIFFRACTION263chain 'Z' and (resid 115 through 128 )Z115 - 128
264X-RAY DIFFRACTION264chain 'Z' and (resid 129 through 138 )Z129 - 138
265X-RAY DIFFRACTION265chain 'Z' and (resid 139 through 155 )Z139 - 155
266X-RAY DIFFRACTION266chain 'Z' and (resid 156 through 179 )Z156 - 179

+
About Yorodumi

-
News

-
Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

  • Version 3 of the EMDB header file is now the official format.
  • The previous official version 1.9 will be removed from the archive.

Related info.:EMDB header

External links:wwPDB to switch to version 3 of the EMDB data model

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Aug 12, 2020. Covid-19 info

Covid-19 info

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