登録情報 | データベース: PDB / ID: 6w6f |
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タイトル | Structural and catalytic roles of human 18S rRNA methyltransferases DIMT1 in ribosome assembly and translation |
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要素 | Probable dimethyladenosine transferase |
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キーワード | RNA BINDING PROTEIN / RNA modification enzyme |
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機能・相同性 | 機能・相同性情報
18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase / 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity / rRNA (adenine-N6,N6-)-dimethyltransferase activity / positive regulation of rRNA processing / rRNA methylation / rRNA modification in the nucleus and cytosol / small-subunit processome / ribosomal small subunit biogenesis / nucleolus / RNA binding ...18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase / 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity / rRNA (adenine-N6,N6-)-dimethyltransferase activity / positive regulation of rRNA processing / rRNA methylation / rRNA modification in the nucleus and cytosol / small-subunit processome / ribosomal small subunit biogenesis / nucleolus / RNA binding / nucleoplasm / cytosol類似検索 - 分子機能 Helicase, Ruva Protein; domain 3 - #480 / Ribosomal RNA adenine dimethylase / Ribosomal RNA adenine methylase transferase, conserved site / Ribosomal RNA adenine dimethylases signature. / Ribosomal RNA adenine methylase transferase, N-terminal / Ribosomal RNA adenine dimethylases / Ribosomal RNA adenine methyltransferase KsgA/Erm / Ribosomal RNA adenine dimethylase / rRNA adenine N(6)-methyltransferase family profile. / Helicase, Ruva Protein; domain 3 ...Helicase, Ruva Protein; domain 3 - #480 / Ribosomal RNA adenine dimethylase / Ribosomal RNA adenine methylase transferase, conserved site / Ribosomal RNA adenine dimethylases signature. / Ribosomal RNA adenine methylase transferase, N-terminal / Ribosomal RNA adenine dimethylases / Ribosomal RNA adenine methyltransferase KsgA/Erm / Ribosomal RNA adenine dimethylase / rRNA adenine N(6)-methyltransferase family profile. / Helicase, Ruva Protein; domain 3 / Vaccinia Virus protein VP39 / S-adenosyl-L-methionine-dependent methyltransferase superfamily / Rossmann fold / Orthogonal Bundle / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 3.2 Å |
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データ登録者 | Shen, H. / Stoute, J. |
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資金援助 | 米国, 1件 組織 | 認可番号 | 国 |
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National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | 1R35GM133721-01 | 米国 |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2020 タイトル: Structural and catalytic roles of the human 18SrRNA methyltransferases DIMT1 in ribosome assembly and translation. 著者: Shen, H. / Stoute, J. / Liu, K.F. |
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履歴 | 登録 | 2020年3月16日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2020年7月8日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2020年7月15日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed ..._citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation_author.identifier_ORCID |
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改定 1.2 | 2020年9月2日 | Group: Database references / カテゴリ: citation Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation.title |
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改定 1.3 | 2023年10月18日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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