Entry | Database: PDB / ID: 6vtr |
---|
Title | Crystal structure of G16S human Galectin-7 mutant |
---|
Components | Galectin-7 |
---|
Keywords | SUGAR BINDING PROTEIN / Human Galectin-7 / lactose-furanose |
---|
Function / homology | Function and homology information
Differentiation of keratinocytes in interfollicular epidermis in mammalian skin / heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules / carbohydrate binding / apoptotic process / extracellular space / extracellular exosome / nucleus / cytoplasmSimilarity search - Function Galectin-like / Galactoside-binding lectin / Galectin / Galectin, carbohydrate recognition domain / Galactoside-binding lectin / Galactoside-binding lectin (galectin) domain profile. / Concanavalin A-like lectin/glucanase domain superfamilySimilarity search - Domain/homology |
---|
Biological species | Homo sapiens (human) |
---|
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 2.3 Å |
---|
Authors | Pham, N.T.H. / Calmettes, C. / Doucet, N. |
---|
Funding support | Canada, United States, 6items Organization | Grant number | Country |
---|
Natural Sciences and Engineering Research Council (NSERC, Canada) | RGPIN 2016-05557 | Canada | National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | R01GM105978 | United States | Fonds de Recherche du Quebec - Sante (FRQS) | Research Scholar Senior Career Award (281993) | Canada | Fonds de Recherche du Quebec - Sante (FRQS) | Junior 1 (251848) | Canada | | RGPIN-2017-06091 | Canada | Fonds de Recherche du Quebec - Sante (FRQS) | Doctoral Training scholarship (287239) | Canada |
|
---|
Citation | Journal: J.Biol.Chem. / Year: 2021 Title: Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7. Authors: Pham, N.T.H. / Letourneau, M. / Fortier, M. / Begin, G. / Al-Abdul-Wahid, M.S. / Pucci, F. / Folch, B. / Rooman, M. / Chatenet, D. / St-Pierre, Y. / Lague, P. / Calmettes, C. / Doucet, N. |
---|
History | Deposition | Feb 13, 2020 | Deposition site: RCSB / Processing site: RCSB |
---|
Revision 1.0 | Aug 25, 2021 | Provider: repository / Type: Initial release |
---|
Revision 1.1 | Nov 17, 2021 | Group: Database references / Category: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
---|
Revision 1.2 | Nov 24, 2021 | Group: Database references / Category: citation / Item: _citation.journal_volume |
---|
Revision 1.3 | Oct 11, 2023 | Group: Data collection / Refinement description Category: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
---|
|
---|