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Yorodumi- PDB-6tr2: Pre-folded structures govern folding pathways of human telomeric ... -
+Open data
-Basic information
Entry | Database: PDB / ID: 6tr2 | ||||||||||||||||||||||||||||||||||
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Title | Pre-folded structures govern folding pathways of human telomeric G-quadruplexes | ||||||||||||||||||||||||||||||||||
Components | DNA (5'-D(*Keywords | DNA / human telomere / G-quadruplex | Function / homology | DNA / DNA (> 10) | Function and homology information Biological species | Homo sapiens (human) | Method | SOLUTION NMR / simulated annealing | Authors | Wang, B. / Frelih, T. / Plavec, J. / Sket, P. | Funding support | Slovenia, 3items |
Citation | Journal: Nucleic Acids Res. / Year: 2020 | Title: Pre-folded structures govern folding pathways of human telomeric G-quadruplexes. Authors: Frelih, T. / Wang, B. / Plavec, J. / Sket, P. History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 6tr2.cif.gz | 151.2 KB | Display | PDBx/mmCIF format |
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PDB format | pdb6tr2.ent.gz | 120.4 KB | Display | PDB format |
PDBx/mmJSON format | 6tr2.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 6tr2_validation.pdf.gz | 318.8 KB | Display | wwPDB validaton report |
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Full document | 6tr2_full_validation.pdf.gz | 369.7 KB | Display | |
Data in XML | 6tr2_validation.xml.gz | 7.3 KB | Display | |
Data in CIF | 6tr2_validation.cif.gz | 11.4 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/tr/6tr2 ftp://data.pdbj.org/pub/pdb/validation_reports/tr/6tr2 | HTTPS FTP |
-Related structure data
Similar structure data | |
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Other databases |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: DNA chain | Mass: 7287.690 Da / Num. of mol.: 1 / Source method: obtained synthetically / Source: (synth.) Homo sapiens (human) |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||||||||
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NMR experiment |
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-Sample preparation
Details |
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Sample |
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Sample conditions | Ionic strength: 0 mM / Label: conditions_1 / pH: 5 / Pressure: 1 atm / Temperature: 278 K |
-NMR measurement
NMR spectrometer | Type: Agilent Agilent Agilent Technologies DD2 600 MHz NMR spectrometer Manufacturer: Agilent Model: Agilent Agilent Technologies DD2 600 MHz NMR spectrometer Field strength: 600 MHz |
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-Processing
NMR software |
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Refinement | Method: simulated annealing / Software ordinal: 2 | |||||||||||||||
NMR representative | Selection criteria: lowest energy | |||||||||||||||
NMR ensemble | Conformer selection criteria: structures with the least restraint violations Conformers calculated total number: 100 / Conformers submitted total number: 10 |