- PDB-6p67: Crystal Structure of a Complex of human IL-7Ralpha with an anti-I... -
+
データを開く
IDまたはキーワード:
読み込み中...
-
基本情報
登録情報
データベース: PDB / ID: 6p67
タイトル
Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha 2B8 Fab
要素
Anti-IL-7R 2B8 Fab heavy chain
Interleukin-7 receptor subunit alpha
anti-IL-7R 2B8 Fab light chain
キーワード
IMMUNE SYSTEM / Interleukin-7 receptor extracellular dohmain / antibody 2B8 Fab fragment / protein polymer
機能・相同性
機能・相同性情報
interleukin-7 receptor activity / interleukin-7-mediated signaling pathway / positive regulation of receptor signaling pathway via STAT / negative regulation of T cell mediated cytotoxicity / regulation of DNA recombination / positive regulation of T cell differentiation in thymus / negative regulation of T cell apoptotic process / cellular homeostasis / cytokine receptor activity / regulation of cell size ...interleukin-7 receptor activity / interleukin-7-mediated signaling pathway / positive regulation of receptor signaling pathway via STAT / negative regulation of T cell mediated cytotoxicity / regulation of DNA recombination / positive regulation of T cell differentiation in thymus / negative regulation of T cell apoptotic process / cellular homeostasis / cytokine receptor activity / regulation of cell size / B cell proliferation / T cell homeostasis / B cell homeostasis / hemopoiesis / lymph node development / Interleukin-7 signaling / antigen binding / positive regulation of receptor signaling pathway via JAK-STAT / clathrin-coated endocytic vesicle membrane / cell morphogenesis / T cell mediated cytotoxicity / cytokine-mediated signaling pathway / Cargo recognition for clathrin-mediated endocytosis / Clathrin-mediated endocytosis / gene expression / T cell differentiation in thymus / cell surface receptor signaling pathway / defense response to Gram-positive bacterium / immune response / external side of plasma membrane / positive regulation of cell population proliferation / positive regulation of gene expression / signal transduction / extracellular region / nucleoplasm / plasma membrane / cytosol 類似検索 - 分子機能
Immunoglobulin-like - #1870 / IL-7Ralpha, fibronectin type III domain / Fibronectin type III domain / Short hematopoietin receptor family 1 signature. / Short hematopoietin receptor, family 1, conserved site / Fibronectin type III domain / Fibronectin type-III domain profile. / Fibronectin type III / Fibronectin type III superfamily / Immunoglobulins ...Immunoglobulin-like - #1870 / IL-7Ralpha, fibronectin type III domain / Fibronectin type III domain / Short hematopoietin receptor family 1 signature. / Short hematopoietin receptor, family 1, conserved site / Fibronectin type III domain / Fibronectin type-III domain profile. / Fibronectin type III / Fibronectin type III superfamily / Immunoglobulins / Immunoglobulin-like fold / Immunoglobulin-like / Sandwich / Mainly Beta 類似検索 - ドメイン・相同性