登録情報 データベース : PDB / ID : 6ogn 構造の表示 ダウンロードとリンクタイトル Crystal structure of mouse protein arginine methyltransferase 7 in complex with SGC8158 chemical probe 要素Protein arginine N-methyltransferase 7 詳細 キーワード TRANSFERASE / PRMT7 / SGC8158 / chemical probe / Structural Genomics / Structural Genomics Consortium機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
type III protein arginine methyltransferase / protein-arginine omega-N monomethyltransferase activity / histone H4 methyltransferase activity / protein-arginine omega-N symmetric methyltransferase activity / peptidyl-arginine methylation / histone H4R3 methyltransferase activity / RMTs methylate histone arginines / genomic imprinting / S-adenosylmethionine-dependent methyltransferase activity / ribonucleoprotein complex binding ... type III protein arginine methyltransferase / protein-arginine omega-N monomethyltransferase activity / histone H4 methyltransferase activity / protein-arginine omega-N symmetric methyltransferase activity / peptidyl-arginine methylation / histone H4R3 methyltransferase activity / RMTs methylate histone arginines / genomic imprinting / S-adenosylmethionine-dependent methyltransferase activity / ribonucleoprotein complex binding / spliceosomal snRNP assembly / fibrillar center / histone binding / nucleoplasm / nucleus / cytosol 類似検索 - 分子機能 Protein arginine N-methyltransferase PRMT7 / Ribosomal protein L11 methyltransferase (PrmA) / Hnrnp arginine n-methyltransferase1 / Hnrnp arginine n-methyltransferase1 / Protein arginine N-methyltransferase / SAM-dependent methyltransferase PRMT-type domain profile. / Vaccinia Virus protein VP39 / Distorted Sandwich / S-adenosyl-L-methionine-dependent methyltransferase superfamily / Rossmann fold ... Protein arginine N-methyltransferase PRMT7 / Ribosomal protein L11 methyltransferase (PrmA) / Hnrnp arginine n-methyltransferase1 / Hnrnp arginine n-methyltransferase1 / Protein arginine N-methyltransferase / SAM-dependent methyltransferase PRMT-type domain profile. / Vaccinia Virus protein VP39 / Distorted Sandwich / S-adenosyl-L-methionine-dependent methyltransferase superfamily / Rossmann fold / 3-Layer(aba) Sandwich / Mainly Beta / Alpha Beta 類似検索 - ドメイン・相同性 Chem-MJ7 / Protein arginine N-methyltransferase 7 類似検索 - 構成要素生物種 Mus musculus (ハツカネズミ)手法 X線回折 / シンクロトロン / フーリエ合成 / 解像度 : 2.4 Å 詳細データ登録者 Halabelian, L. / Dong, A. / Zeng, H. / Li, Y. / Hutchinson, A. / Seitova, A. / Bountra, C. / Edwards, A.M. / Arrowsmith, C.H. / Structural Genomics Consortium (SGC) 引用ジャーナル : Nat Commun / 年 : 2020タイトル : Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response.著者: Szewczyk, M.M. / Ishikawa, Y. / Organ, S. / Sakai, N. / Li, F. / Halabelian, L. / Ackloo, S. / Couzens, A.L. / Eram, M. / Dilworth, D. / Fukushi, H. / Harding, R. / Dela Sena, C.C. / Sugo, T. ... 著者 : Szewczyk, M.M. / Ishikawa, Y. / Organ, S. / Sakai, N. / Li, F. / Halabelian, L. / Ackloo, S. / Couzens, A.L. / Eram, M. / Dilworth, D. / Fukushi, H. / Harding, R. / Dela Sena, C.C. / Sugo, T. / Hayashi, K. / McLeod, D. / Zepeda, C. / Aman, A. / Sanchez-Osuna, M. / Bonneil, E. / Takagi, S. / Al-Awar, R. / Tyers, M. / Richard, S. / Takizawa, M. / Gingras, A.C. / Arrowsmith, C.H. / Vedadi, M. / Brown, P.J. / Nara, H. / Barsyte-Lovejoy, D. 履歴 登録 2019年4月3日 登録サイト : RCSB / 処理サイト : RCSB置き換え 2019年4月17日 ID : 6NPG 改定 1.0 2019年4月17日 Provider : repository / タイプ : Initial release改定 1.1 2022年2月23日 Group : Database references / カテゴリ : citation / citation_author / database_2Item : _citation.country / _citation.journal_abbrev ... _citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _database_2.pdbx_DOI / _database_2.pdbx_database_accession 改定 1.2 2023年10月11日 Group : Data collection / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model
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