[English] 日本語
Yorodumi
- PDB-6ny6: Structure of dimeric Escherichia coli toxin YoeB bound to the The... -

+
Open data


ID or keywords:

Loading...

-
Basic information

Entry
Database: PDB / ID: 6ny6
TitleStructure of dimeric Escherichia coli toxin YoeB bound to the Thermus thermophilus 30S ribosome
Components
  • (30S ribosomal protein ...) x 20
  • 16S rRNA
  • Toxin YoeB
KeywordsRIBOSOME
Function / homology
Function and homology information


global gene silencing by mRNA cleavage / toxin-antitoxin complex / single-species biofilm formation / regulation of growth / RNA catabolic process / mRNA catabolic process / ribosomal small subunit binding / negative regulation of translational initiation / RNA endonuclease activity / RNA endonuclease activity producing 3'-phosphomonoesters, hydrolytic mechanism ...global gene silencing by mRNA cleavage / toxin-antitoxin complex / single-species biofilm formation / regulation of growth / RNA catabolic process / mRNA catabolic process / ribosomal small subunit binding / negative regulation of translational initiation / RNA endonuclease activity / RNA endonuclease activity producing 3'-phosphomonoesters, hydrolytic mechanism / response to heat / ribosomal small subunit biogenesis / ribosomal small subunit assembly / small ribosomal subunit / small ribosomal subunit rRNA binding / cytosolic small ribosomal subunit / endonuclease activity / Hydrolases; Acting on ester bonds / tRNA binding / rRNA binding / structural constituent of ribosome / ribosome / translation / ribonucleoprotein complex / mRNA binding / regulation of DNA-templated transcription / protein homodimerization activity / RNA binding / zinc ion binding / metal ion binding / cytoplasm / cytosol
Similarity search - Function
Toxin YoeB / YoeB-like toxin of bacterial type II toxin-antitoxin system / RelE-like / YaeB-like fold / Toxin-antitoxin system, RelE/ParE toxin domain superfamily / 30s ribosomal protein s13; domain 2 / Ribosomal protein S13/S18, C-terminal domain / Ribosomal protein S20 / 30s Ribosomal Protein S19; Chain A / Ribosomal protein S19/S15 ...Toxin YoeB / YoeB-like toxin of bacterial type II toxin-antitoxin system / RelE-like / YaeB-like fold / Toxin-antitoxin system, RelE/ParE toxin domain superfamily / 30s ribosomal protein s13; domain 2 / Ribosomal protein S13/S18, C-terminal domain / Ribosomal protein S20 / 30s Ribosomal Protein S19; Chain A / Ribosomal protein S19/S15 / Ribosomal protein S3, C-terminal domain / Ribosomal Protein S14/S29 / 30s Ribosomal Protein S14; Chain N / Ribosomal protein S3 C-terminal domain / Ribosomal protein S6/Translation elongation factor EF1B / Dna Ligase; domain 1 - #10 / Ribosomal protein S11/S14 / Ribosomal protein S10 / Helix hairpin bin / Ribosomal Protein S7 / Ribosomal protein S7/S5 / K homology (KH) domain / Helicase, Ruva Protein; domain 3 - #50 / Double Stranded RNA Binding Domain - #20 / Glucose-6-phosphate isomerase like protein; domain 1 / Ribosomal Protein S5; domain 2 - #10 / 30S ribosomal protein Thx / 30S ribosomal protein Thx / 30S ribosomal protein / GMP Synthetase; Chain A, domain 3 / Ribosomal Protein S5; domain 2 / Ribosomal protein S14, type Z / Double Stranded RNA Binding Domain / Helicase, Ruva Protein; domain 3 / Nucleic acid-binding proteins / Dna Ligase; domain 1 / Methane Monooxygenase Hydroxylase; Chain G, domain 1 / Ribosomal protein S3, bacterial-type / Ribosomal protein S14/S29 / Ribosomal protein S19, bacterial-type / Ribosomal protein S13, bacterial-type / Ribosomal protein S6, conserved site / Ribosomal protein S6 signature. / Ribosomal protein S7, bacterial/organellar-type / Ribosomal protein S11, bacterial-type / Ribosomal protein S20 / Ribosomal protein S20 superfamily / Ribosomal protein S20 / Ribosomal protein S4, bacterial-type / 30S ribosomal protein S17 / Ribosomal protein S5, bacterial-type / Ribosomal protein S6, plastid/chloroplast / Ribosomal protein S2, bacteria/mitochondria/plastid / Ribosomal protein S9, bacterial/plastid / Ribosomal protein S18, conserved site / Ribosomal protein S18 signature. / Ribosomal protein S16 / Ribosomal protein S16 domain superfamily / Ribosomal protein S16 / Ribosomal protein S15, bacterial-type / Ribosomal protein S6 / Ribosomal protein S6 / Ribosomal protein S6 superfamily / Ribosomal protein S12, bacterial-type / Translation elongation factor EF1B/ribosomal protein S6 / Ribosomal protein S18 / Ribosomal protein S18 / Ribosomal protein S18 superfamily / Few Secondary Structures / Irregular / K Homology domain / K homology RNA-binding domain / OB fold (Dihydrolipoamide Acetyltransferase, E2P) / Ribosomal protein S3, conserved site / Ribosomal protein S3 signature. / Ribosomal protein S10, conserved site / Ribosomal protein S10 signature. / Ribosomal protein S14, conserved site / Ribosomal protein S14 signature. / Ribosomal protein S2 signature 1. / Nucleotidyltransferase; domain 5 / KH domain / Type-2 KH domain profile. / K Homology domain, type 2 / Ribosomal protein S3, C-terminal / Ribosomal protein S3, C-terminal domain / Ribosomal protein S3, C-terminal domain superfamily / Ribosomal protein S15/S19, conserved site / Ribosomal protein S19 signature. / Ribosomal protein S10 / Ribosomal protein S5, N-terminal, conserved site / Ribosomal protein S5 signature. / Ribosomal protein S19/S15 / Ribosomal protein S19/S15, superfamily / Ribosomal protein S19 / Helix Hairpins / Ribosomal protein S2, conserved site / Ribosomal protein S2 / Ribosomal protein S2, flavodoxin-like domain superfamily / Ribosomal protein S2
Similarity search - Domain/homology
IRON/SULFUR CLUSTER / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / Toxin YoeB / Small ribosomal subunit protein uS14 / Small ribosomal subunit protein uS17 / Small ribosomal subunit protein uS8 / Small ribosomal subunit protein uS7 ...IRON/SULFUR CLUSTER / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / Toxin YoeB / Small ribosomal subunit protein uS14 / Small ribosomal subunit protein uS17 / Small ribosomal subunit protein uS8 / Small ribosomal subunit protein uS7 / Toxin YoeB / Small ribosomal subunit protein uS2 / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS4 / Small ribosomal subunit protein uS9 / Small ribosomal subunit protein uS11 / Small ribosomal subunit protein uS13 / Small ribosomal subunit protein bS20 / Small ribosomal subunit protein uS12 / Small ribosomal subunit protein uS10 / Small ribosomal subunit protein uS19 / Small ribosomal subunit protein uS5 / Small ribosomal subunit protein bTHX / Small ribosomal subunit protein uS15 / Small ribosomal subunit protein bS16 / Small ribosomal subunit protein bS6 / Small ribosomal subunit protein bS18
Similarity search - Component
Biological speciesEscherichia coli (E. coli)
Thermus thermophilus HB8 (bacteria)
MethodX-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 3.74 Å
AuthorsPavelich, I.J. / Hoffer, E.D. / Maehigashi, T. / Dunham, C.M.
Funding support United States, 2items
OrganizationGrant numberCountry
National Science Foundation (NSF, United States)MCB 0953714 United States
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)GM093278 United States
CitationJournal: Nucleic Acids Res. / Year: 2019
Title: Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Authors: Pavelich, I.J. / Maehigashi, T. / Hoffer, E.D. / Ruangprasert, A. / Miles, S.J. / Dunham, C.M.
History
DepositionFeb 11, 2019Deposition site: RCSB / Processing site: RCSB
Revision 1.0Aug 21, 2019Provider: repository / Type: Initial release
Revision 1.1Oct 2, 2019Group: Data collection / Database references / Category: citation / citation_author
Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year
Revision 1.2Nov 6, 2019Group: Data collection / Database references / Structure summary
Category: audit_author / citation
Item: _citation.journal_volume / _citation.page_first / _citation.page_last
Revision 1.3Nov 27, 2019Group: Author supporting evidence / Category: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization
Revision 1.4Oct 11, 2023Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description
Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn / struct_conn_type
Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_seq_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.conn_type_id / _struct_conn.id / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.pdbx_ptnr1_PDB_ins_code / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_conn_type.id
Revision 1.5Oct 30, 2024Group: Structure summary / Category: pdbx_entry_details / pdbx_modification_feature

-
Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

Downloads & links

-
Assembly

Deposited unit
A: 16S rRNA
B: 30S ribosomal protein S2
C: 30S ribosomal protein S3
D: 30S ribosomal protein S4
E: 30S ribosomal protein S5
F: 30S ribosomal protein S6
G: 30S ribosomal protein S7
H: 30S ribosomal protein S8
I: 30S ribosomal protein S9
J: 30S ribosomal protein S10
K: 30S ribosomal protein S11
L: 30S ribosomal protein S12
M: 30S ribosomal protein S13
N: 30S ribosomal protein S14 type Z
O: 30S ribosomal protein S15
P: 30S ribosomal protein S16
Q: 30S ribosomal protein S17
R: 30S ribosomal protein S18
S: 30S ribosomal protein S19
T: 30S ribosomal protein S20
U: 30S ribosomal protein Thx
Y: Toxin YoeB
Z: Toxin YoeB
hetero molecules


Theoretical massNumber of molelcules
Total (without water)809,056209
Polymers804,16723
Non-polymers4,889186
Water00
1


  • Idetical with deposited unit
  • defined by author
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Unit cell
Length a, b, c (Å)401.710, 401.710, 175.440
Angle α, β, γ (deg.)90.00, 90.00, 90.00
Int Tables number92
Space group name H-MP41212

-
Components

-
30S ribosomal protein ... , 20 types, 20 molecules BCDEFGHIJKLMNOPQRSTU

#2: Protein 30S ribosomal protein S2


Mass: 29317.703 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: P80371
#3: Protein 30S ribosomal protein S3


Mass: 26751.076 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: P80372
#4: Protein 30S ribosomal protein S4


Mass: 24373.447 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: P80373
#5: Protein 30S ribosomal protein S5


Mass: 17583.416 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: Q5SHQ5
#6: Protein 30S ribosomal protein S6 / TS9


Mass: 11988.753 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: Q5SLP8
#7: Protein 30S ribosomal protein S7


Mass: 18050.973 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: P17291
#8: Protein 30S ribosomal protein S8


Mass: 15868.570 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: P0DOY9
#9: Protein 30S ribosomal protein S9


Mass: 14410.614 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: P80374
#10: Protein 30S ribosomal protein S10


Mass: 11954.968 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: Q5SHN7
#11: Protein 30S ribosomal protein S11


Mass: 13737.868 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: P80376
#12: Protein 30S ribosomal protein S12


Mass: 14637.384 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: Q5SHN3
#13: Protein 30S ribosomal protein S13


Mass: 14338.861 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: P80377
#14: Protein 30S ribosomal protein S14 type Z


Mass: 7158.725 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: P0DOY6
#15: Protein 30S ribosomal protein S15


Mass: 10578.407 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: Q5SJ76
#16: Protein 30S ribosomal protein S16


Mass: 10409.983 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: Q5SJH3
#17: Protein 30S ribosomal protein S17


Mass: 12325.655 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: P0DOY7
#18: Protein 30S ribosomal protein S18


Mass: 10258.299 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: Q5SLQ0
#19: Protein 30S ribosomal protein S19


Mass: 10605.464 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: Q5SHP2
#20: Protein 30S ribosomal protein S20


Mass: 11736.143 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: P80380
#21: Protein/peptide 30S ribosomal protein Thx / S31


Mass: 3350.030 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria) / Variant: HB8 / ATCC 27634 / DSM 579 / References: UniProt: Q5SIH3

-
RNA chain / Protein , 2 types, 3 molecules AYZ

#1: RNA chain 16S rRNA


Mass: 494263.469 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus HB8 (bacteria)
#22: Protein Toxin YoeB


Mass: 10233.658 Da / Num. of mol.: 2
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Escherichia coli (E. coli) / Gene: yoeB / Production host: Escherichia coli BL21(DE3) (bacteria) / References: UniProt: A0A127GIW6, UniProt: P69348*PLUS

-
Non-polymers , 3 types, 186 molecules

#23: Chemical...
ChemComp-MG / MAGNESIUM ION


Mass: 24.305 Da / Num. of mol.: 184 / Source method: obtained synthetically / Formula: Mg
#24: Chemical ChemComp-SF4 / IRON/SULFUR CLUSTER


Mass: 351.640 Da / Num. of mol.: 1 / Source method: obtained synthetically / Formula: Fe4S4
#25: Chemical ChemComp-ZN / ZINC ION


Mass: 65.409 Da / Num. of mol.: 1 / Source method: obtained synthetically / Formula: Zn

-
Details

Has protein modificationY

-
Experimental details

-
Experiment

ExperimentMethod: X-RAY DIFFRACTION / Number of used crystals: 1

-
Sample preparation

CrystalDensity Matthews: 4.44 Å3/Da / Density % sol: 72.28 %
Crystal growTemperature: 277 K / Method: vapor diffusion, sitting drop / pH: 6.5
Details: MPD, AMMONIUM CHLORIDE, POTASSIUM CHLORIDE, MAGNESIUM ACETATE, SODIUM CACODYLATE, pH 6.5

-
Data collection

DiffractionMean temperature: 100 K / Serial crystal experiment: N
Diffraction sourceSource: SYNCHROTRON / Site: APS / Beamline: 24-ID-C / Wavelength: 0.9792 Å
DetectorType: DECTRIS PILATUS 6M-F / Detector: PIXEL / Date: Dec 12, 2012
RadiationProtocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelengthWavelength: 0.9792 Å / Relative weight: 1
ReflectionResolution: 3.74→49.826 Å / Num. obs: 145546 / % possible obs: 96.9 % / Redundancy: 3.29 % / CC1/2: 0.999 / Rmerge(I) obs: 0.06808 / Net I/σ(I): 10.95
Reflection shellResolution: 3.74→3.874 Å / Redundancy: 2.17 % / Rmerge(I) obs: 0.4847 / Mean I/σ(I) obs: 1.08 / Num. unique obs: 9392 / CC1/2: 0.673 / % possible all: 85.1

-
Phasing

PhasingMethod: molecular replacement

-
Processing

Software
NameVersionClassificationNB
PHENIXdev_3406refinement
XDSdata reduction
XSCALEdata scaling
PHASERphasing
PDB_EXTRACT3.24data extraction
RefinementMethod to determine structure: MOLECULAR REPLACEMENT
Starting model: 1J5E

1j5e


Resolution: 3.74→49.826 Å / SU ML: 0.42 / Cross valid method: FREE R-VALUE / σ(F): 1.35 / Phase error: 23.25 / Stereochemistry target values: ML
RfactorNum. reflection% reflection
Rfree0.2242 7165 5 %
Rwork0.2057 --
obs0.2067 143162 97.27 %
Solvent computationShrinkage radii: 0.9 Å / VDW probe radii: 1.11 Å / Solvent model: FLAT BULK SOLVENT MODEL
Refinement stepCycle: LAST / Resolution: 3.74→49.826 Å
ProteinNucleic acidLigandSolventTotal
Num. atoms20542 32514 193 0 53249
Refine LS restraints
Refine-IDTypeDev idealNumber
X-RAY DIFFRACTIONf_bond_d0.00857292
X-RAY DIFFRACTIONf_angle_d1.16384853
X-RAY DIFFRACTIONf_dihedral_angle_d22.85331455
X-RAY DIFFRACTIONf_chiral_restr0.05810612
X-RAY DIFFRACTIONf_plane_restr0.0075128
LS refinement shell
Resolution (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkRefine-ID% reflection obs (%)
3.7401-3.78250.35572270.3433915X-RAY DIFFRACTION86
3.7825-3.8270.30621880.31614312X-RAY DIFFRACTION93
3.827-3.87370.28462210.29734427X-RAY DIFFRACTION96
3.8737-3.92270.29742480.29364523X-RAY DIFFRACTION98
3.9227-3.97430.27142300.2664614X-RAY DIFFRACTION100
3.9743-4.02870.26492520.27164543X-RAY DIFFRACTION100
4.0287-4.08620.25842690.26164591X-RAY DIFFRACTION100
4.0862-4.14720.27852340.25174593X-RAY DIFFRACTION99
4.1472-4.2120.28282520.24654592X-RAY DIFFRACTION100
4.212-4.2810.26122210.24564629X-RAY DIFFRACTION99
4.281-4.35480.27172700.24114520X-RAY DIFFRACTION99
4.3548-4.43390.24122320.23864549X-RAY DIFFRACTION98
4.4339-4.51910.24732640.22874516X-RAY DIFFRACTION98
4.5191-4.61130.22442330.22224590X-RAY DIFFRACTION99
4.6113-4.71150.25742270.21064615X-RAY DIFFRACTION99
4.7115-4.8210.23912130.2084607X-RAY DIFFRACTION99
4.821-4.94150.24292540.20714596X-RAY DIFFRACTION99
4.9415-5.0750.23732520.20254584X-RAY DIFFRACTION99
5.075-5.22410.22312120.19754630X-RAY DIFFRACTION99
5.2241-5.39260.22552290.19534583X-RAY DIFFRACTION99
5.3926-5.58510.21662310.19324516X-RAY DIFFRACTION97
5.5851-5.80840.20282390.1894618X-RAY DIFFRACTION99
5.8084-6.07230.24042130.19624608X-RAY DIFFRACTION98
6.0723-6.39180.20912420.19444574X-RAY DIFFRACTION98
6.3918-6.79130.23162570.19044547X-RAY DIFFRACTION97
6.7913-7.31420.19852470.18584547X-RAY DIFFRACTION96
7.3142-8.04750.22052380.17974532X-RAY DIFFRACTION96
8.0475-9.20560.20782620.1894520X-RAY DIFFRACTION96
9.2056-11.57410.16772460.17984471X-RAY DIFFRACTION93
11.5741-49.83040.19972620.18244535X-RAY DIFFRACTION91
Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

IDL11 (°2)L12 (°2)L13 (°2)L22 (°2)L23 (°2)L33 (°2)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T11 (Å2)T12 (Å2)T13 (Å2)T22 (Å2)T23 (Å2)T33 (Å2)Origin x (Å)Origin y (Å)Origin z (Å)
10.5269181012510.386520018846-0.2257031520630.7911361426990.006433937686710.587238991528-0.106994136885-0.113348736264-0.06947376324850.1385805519840.1193245710770.2772871759990.324212094733-0.0985870867984-0.01372559130961.25552055590.1145694492920.1992445450041.109743252320.1013132138191.49979797329121.6274617261.6511034915-5.71502745402
20.5474382295420.20695691861-0.1896104254910.756107181678-0.06571930385910.6657992932920.0428652512822-0.227670444471-0.07840389980680.4863627785480.09366732652570.2284929135610.1625948213550.124881522238-0.1303088361291.389405617630.1839471202020.1853453655821.223065671080.0178604736451.28967097033140.82919889287.16605739189.4413844474
31.65628907364-0.103883181175-0.6610943527030.5080000187170.2253463597920.983442450680.03548126973250.1551425594560.0885803446609-0.2566281414790.0858661723887-0.263058127418-0.01253220297580.328116807985-0.1225639341871.037539106890.05441654231720.1284890099291.13444098582-0.09471706328191.05115311948174.898629597106.406634921-50.3977123229
40.710059995169-0.2258671964310.09599826559680.317169363538-0.09927452105190.178758301743-0.00205151692398-0.7222763294110.1715802601350.3252639459360.0422255224238-0.0699746242984-0.2473327164060.17722666733-0.003914311294241.47914368863-0.1267844926180.1647024511612.23682599386-0.465440855921.57995745566211.83876232124.38171448115.5147980632
52.60469047156-0.4411068015960.09013813508460.539590661265-0.2324639325110.5039343028680.023072843866-1.141698814190.9618236402660.3451060871070.116478001373-0.396140274239-0.3276656873670.105662738759-0.1349621209981.38342916957-0.2459132632120.09776035174391.90183525548-0.767905217131.6464719502232.90117351132.5234750374.43945975827
61.202055537880.262422175154-0.236018104514-0.01236247454360.02837718406960.2965363271370.0179415578677-0.250864681552-0.4372684867360.1628283690630.119204381248-0.460764791180.216568554960.243223321169-0.1003254598011.420578527440.2462955113850.07293105780161.45670661208-0.07393010751.44225258163168.13470319676.1075194184-24.8351996343
70.774550776308-0.2506433324860.08904507145750.1283804916910.1888745820131.120781782590.432560211685-0.169008350118-0.580812645380.03435293504730.3582342831130.4787088705350.553316073242-0.404648533539-0.553007866372.633620946740.860129471395-1.334726955033.44251950977-0.2679408289493.43782055266210.07094123978.94364422027.79308881536
83.253556900161.18271840570.2696816204333.59748497776-1.354944698450.685110163505-0.13956941097-0.3703719841010.1849347105510.4686093089260.571822065056-0.2507568999230.1390599898710.139119725886-0.2571492996742.278838302580.3001911221-0.6646751434772.3362158763-0.1145844653724.08306755548211.44766252892.633716763214.8417638758
91.79904906307-0.6077055986570.02072278833061.39880349402-1.438142965611.70186170757-0.6101409743160.338883890973-0.3615400819580.114389145290.2322268665520.2051606964110.290166048417-0.4517957546320.2611194559292.620811299120.2031197637270.3614320730422.73362871872-0.2774453164452.51356666479199.54391139584.962146235414.1206719456
104.75917132982-1.26512354242-3.586453675270.2999974665850.9035496514412.721376620890.4678997894430.397207264586-0.1497239941010.150480817312-0.0969488476291-0.6967876061430.0703085472911-0.606299928718-0.140412080462.32004116233-0.116303462823-0.03839241938083.00462234078-0.01623076464741.48164355532199.52684435987.0997560552-1.97915010679
111.95840580607-0.363817627113-1.191171045052.002577010349.776415273664.638743050091.135788944670.947409354362-0.1510084967450.0760167126776-0.689703787032-0.1558286039181.21662175196-1.68939988557-0.5739168186963.58126167597-1.17816851354-1.458785188234.181933515020.5524857476071.30643806876198.85308947793.25772876955.16015434708
122.10837073126-0.4455520514431.161186236143.20224234321-3.204922736213.45979759435-0.3097324238960.250920803277-0.284571485949-0.412315962636-0.293391266594-0.2433469120250.134582583701-0.1682254537480.4914829596022.108353289240.648584485024-0.1679612218632.77668943308-0.1107740753352.70979483665203.89896808585.51256180062.41318465368
131.9931608675.872735452290.8299221597659.35059257303-5.086773259384.50043199564-0.308124767374-1.33650435082-0.632117269213-0.2265263480070.0224874200844-0.04595732656660.194219377954-0.8422017106740.1980537124421.846741909871.255124354210.0107158203013.55647292673-0.8350001284011.65640128076207.77287198377.6329560923.31615824861
140.3096070258190.0957517030658-0.5108626713882.28416253315-1.262809277471.379235553470.2854033930830.464941428960.0993644141814-0.514745150111-0.00711063681140.188708117753-0.033559027166-0.103786470374-0.2488258551983.34879611858-0.346114755322-0.06890435642693.63742547846-0.1145283845721.91912718723206.81993686596.20744576234.63640239043
150.4275962720620.133976228843-0.309380139792-0.0140254463816-0.1343637619880.162739456470.860466204131.84253696543-0.895305291388-0.250814358612-0.641872882322-0.0114443565739-0.138293676774-0.296413041073-0.3279301786752.171079358960.582620346719-0.9273176230683.25909144263-0.03255397447712.78630160678209.62126842678.820651002719.1311505378
160.9334226371691.50989402320.8011785606913.585351398861.307775382661.14837727226-0.0253000146695-0.0936282843880.0806590515687-0.1602489294120.608668127219-0.2841461264810.264557476617-0.3385518967290.05409448786731.50361962414-0.00803366153756-1.164335871122.30214922144-0.6937737250434.02687889039223.47177763178.187459645219.8337863468
173.92368460008-1.956221913630.02556211363074.53982743316-4.454341806985.59516799091-0.06198181165650.439200332496-0.253288755650.130810232462-0.359285457515-0.288789821091-0.570136193096-0.08717102274860.2919569923333.292279235811.01044816552-0.6513592158393.00316692122-0.1448782557352.70096665256219.75839764573.779421011420.3414306231
183.301492193690.6714388369640.09653876777943.13377578485-1.792657265941.08213599277-0.8367184364560.9012753090640.13721795909-0.807737938191-0.438832741472-0.4942151783320.6542061880920.7002814554071.177305861791.987712516290.1520371401320.2526862748241.339799824490.07142566277951.29908945268155.624400171156.808459276-33.7917195254
192.44700579657-0.6032897426491.129338228042.53093021590.6091234727142.564565623730.250616121043-0.3398621446820.748897431021-0.2538014378210.442027307279-0.0820670609865-0.8597389305590.18860538615-0.7391033112531.28978435454-0.1227459062280.6210804892241.242595629510.009512702733441.72602776364162.348895303157.747261534-17.6560946305
209.344071003137.216071352694.475263445555.663904243663.114171806463.266113926680.3234230660830.131666049105-0.5483465169420.340611460234-0.348662125397-0.234240526479-0.1742489402950.423244993377-0.05019758149922.43590120215-0.2101434535280.320147872452.24891542896-1.450388332463.40735850053194.414447419165.340969495-0.166248190115
213.48128624323-0.1475227188620.6658021992461.269092436830.1518196230431.924903902590.2043174971350.2863201589240.191343172035-0.4343343508210.301182392454-0.683315929736-0.4086417080350.366445886431-0.5600611771621.60401216234-0.05277363953750.604936491161.00622050932-0.2097776229121.87481207165.234466054155.317806661-17.1623484817
221.990709847458.053667113911.947292626236.17278053847-9.260483815951.99679626942-0.8429716156970.535207201276-0.1931652624791.300288063790.398184940450.948392526571.085807168410.09718112724440.4932968115272.70711542673-0.1330977261740.4531281896621.14202945788-0.2503574937051.90340952263160.76341229173.041119079-20.3292452488
233.37096669137-0.5858770838121.954520485380.655327808723-1.412196644083.27529122964-0.07468517165940.225445846137-0.003061003681550.409994381314-0.04694314344870.0115310558931-1.849096912960.72097657761-0.09776145340471.87499140067-0.2419818426160.3354034256862.66548281456-0.7676708895371.55895894809210.346893731142.0377107521.221790537
242.21560624446-0.620578179244-2.275216407070.3598984587360.427274810422.5686114269-0.0143786033880.213332008564-0.6034306270110.03627666742930.633134150943-0.401895842448-0.1252117659910.33361629085-0.4604377365941.83002165861-0.102684902710.1027455994032.86219178222-1.3004319932.18479220613208.855645112134.18690742235.3398797565
252.32712590557-1.07715569619-1.775549959473.566050382-1.863694624163.65897081008-0.4897274185090.234553435158-0.169294099338-0.207362183173-0.789226631202-0.4043052851020.1742123867520.5164540406210.8472206225041.6553271987-0.15516431899-0.1587826895663.37763477828-0.9305993207322.27103422255206.926174331143.41561337734.2577454454
260.869862137340.761320894373-0.9695134953491.30763175688-1.150576345861.686060188950.1323969154-0.1188590969510.4660810057380.909831189193-0.233786667235-0.2770840017440.8771566900440.767341784885-0.05371191784662.576891887980.09384288436870.2010820663333.79230807088-0.6756453408331.38626938107200.002886437141.24431623144.0695653291
272.82776476063-0.425371031554-0.3308505566582.23611312659-0.3971593635080.09240944674140.4683157410290.7967546032651.059351146050.214495761444-0.1196130784120.195778183856-0.436502652578-0.110694339753-0.1142270724751.75699938561-0.04536623172390.0980352907693.16300014013-0.9301138684071.50727085069199.54282125144.51205859535.8416507786
281.242922538511.87280999043-1.843183782383.19787292924-2.012786734534.09688898253-0.188284186010.00387851501441-0.862661354773-0.162985907765-0.218381932401-0.396593475342-0.1463630907020.6800181411890.02197452571.60977124720.196640063170.4004125447072.72386421994-0.8446946194921.57813547061189.227901766131.0933974226.4222872691
292.56397619423-0.00621763370726-0.9850969820543.92130739459-1.701774912823.95461159455-0.014337826042-0.282952158310.553972413240.0358616814440.2423413403310.9864592120160.557505637873-0.864261123636-0.1112140417271.19530206752-0.1283320946860.02216612226032.71999761281-0.2016282943531.50939349046185.733614377129.75781334916.8020977328
303.376522308530.4908990828580.007185595458351.4853280056-0.03764478579072.73657200153-0.0109642969608-1.124876890560.228649824416-0.0322396002321-0.03253304730780.254949419581-0.637751370175-1.08027822847-0.06348587999871.21827304444-0.0736784892820.1244532307872.98915608671-0.9708488419971.66938783152195.745691219135.91486483716.8664289964
315.82921537055-0.3577174300540.9113156702516.03339841708-0.7758080358435.416620135-0.102637407396-0.0658729455624-0.500737004286-0.2880727370521.48565679188-0.857800982008-0.8809039950070.511010976267-1.242142955011.86509230896-0.4267530807760.02365949098521.90817267417-0.2557395210711.52023488008155.614334157106.04819454533.9738565964
324.707383122843.1458940321.00208516465.41401298927-1.335247554041.416212812910.193411704028-0.6531398343390.0177100295962-0.0628980986418-0.2190038610180.319131805742-0.4868514128950.4078299780260.1788707581361.92698470857-0.3303521567870.4578543314332.05432371518-0.6390798763921.72721649592152.944503876115.62207318640.9028964512
335.284844708660.9766567803330.9891475516071.600430238310.5456067986821.365632838591.3885939258-0.6449843717690.5724065463510.374457791782-0.405057579739-0.36354157905-0.5527125365131.6581585117-1.013534097131.739191443350.03300674992470.1395917317091.80804114518-0.1358878742181.16889693425159.51685476112.66183040224.994994955
346.70652860035-0.2367316153941.726218163457.18310097086-0.1499464282894.680914201950.4456017429750.987346706861-1.329963143540.56176603905-0.811626188280.8595718559031.84307139975-0.5451552177680.3434565874521.72544886411-0.01889419574490.3305401393121.3225552154-0.4361811701961.50655323363142.052997842101.68399663920.0704144745
352.561130429270.6609983242470.2695889174993.64198268278-1.475892809672.88500832390.704089420830.05124989149870.3207238064880.604621622733-0.2874333661170.3803079544-0.162790712839-0.0347369617717-0.4757650759131.412675174440.1806547490960.368733175371.15706273953-0.07312678793941.04208423433133.981606717104.27108198833.3268998019
361.536777127942.782979764920.3771486502545.101979667110.6832588800770.0982531924362-0.286109063533-0.288771580276-0.194353168092-0.400619369050.878813488877-0.52702555097-0.9731227324740.401809606655-0.5574661606182.26053879650.03882254817470.5335696133542.17813523021-0.2860056794151.39664375792133.076581493104.72652749751.8401103547
372.553771631760.2455234164491.541356614992.406522905540.328752354593.132915074820.251845489049-0.7202011612520.6555877466840.772312023011-0.3241105697140.589077939396-0.493926718982-0.337792194420.129921318931.960381891960.2950961733230.3651814622781.52517277039-0.3340930365091.52719863428129.3066983114.6723834841.9476853032
384.09486020837-0.349526346871-2.972631818583.11251838326-0.1055448170162.72902305828-0.188306055854-0.05983506128731.913558928220.2876135505250.7137208625990.281033612226-1.04198973983-0.717481233579-0.839803611431.99626986280.384755286098-0.1208902768920.986602867483-0.006828568023151.42607918763136.24873003118.04392373626.2759084296
391.994989173810.6705502701135.602069611872.00222558735-3.411869714588.5884211641-0.02823177520010.833834729604-0.147103140010.1366291085010.05849661576980.946404452332-1.22591238880.305808112657-0.1252397685351.409777499250.2315476477440.2971369732521.282077922990.4412847786291.68992155975147.750313359110.81561315714.1874485175
405.13786821804-0.666938113895-1.11453316942.3846098726-0.1555876274042.204704103790.496859471436-0.9338971131640.120915090710.0871801563160.0663832493116-0.295578242349-0.1819195844090.805267623073-0.5603103347051.23518548651-0.2065194054730.01129901650821.74285240417-0.5575032681571.34492183274172.554266075124.3491846453.14652887932
417.502216072151.41308745967-1.628022628380.334772183607-0.6892629796632.520753979130.478772472929-0.267711847331-0.1066534138590.630697400803-0.4704534202860.7965634877540.211693442498-0.3034342539430.1355068266551.49163943896-0.1484473905310.2913642933681.2808308209-0.5186306130611.60950439373160.895413811130.0785703344.92240056672
425.662656015232.782015719930.07140727948772.53756576831.265184100263.93910924925-0.7248849393930.837760646611.610438494910.4688525227550.285399390119-0.251663924347-0.6958423081970.07601258804460.4472758842761.90983136207-0.5923535160120.4552003978541.21589993553-0.1889920959051.25680003024167.527518109133.6982970075.24783092154
439.250812871762.42239964542-1.287355929175.57939833387-0.1962094525884.773355309110.737666687126-0.2305748324560.8967602153220.013724542855-0.1913991009681.29502232024-0.639988202848-0.292025439957-0.4840458054831.018437198710.2802152879920.277642946651.275569205370.1006599534631.84079229296143.974778631127.9193264980.842285831128
448.611537564882.07281731252-3.070403649531.80457953835-2.636337941834.16426913782-0.864255387941-0.162865395174-0.4536284761270.565240895980.267181664889-0.1235121074880.111080760075-0.1881789256870.6284800552650.9808730091780.2060607804250.2795105555990.848812279937-0.1641119635251.3022058481148.040702604117.400882747-2.6710153717
452.91432652404-0.04862895291362.035251687357.943131829063.550717182733.39979139575-0.00143239095046-1.34061939515-1.222189214990.811968677545-0.197701127750.1068002648290.0409694445227-0.06285875078250.1755561638561.014031990140.06720638786840.1338533511181.26460860683-0.1227617589971.37814267145153.834991928120.9205128846.01972072536
467.265817363930.407440719312-1.656209450474.590128806490.1696625430991.98036635069-0.1306208895470.270819882592-0.14316758811-0.107139448694-0.0485235473046-0.0662852045350.5793985544460.2605910174540.085520012131.150087201570.01310817278860.2554138128991.31850050147-0.1178240710251.00750255561153.198135351120.395060575-2.36185725706
477.52101642108-1.989022888961.138696431197.50847514617-1.45345234655.54321524851-0.2306829306380.4139098196140.7186195389260.529734608265-0.4899693432810.935062672636-0.689419684441-0.8697394235870.5791253588851.329759369520.2361758915610.1225464265231.50770601851-0.1432225894881.39123266812135.258916014134.957311153-9.68308537071
482.751257538450.978643695261-0.7769725518257.55462940447-0.6381458096859.15340055094-0.242434114494-1.198838935030.4062113079530.816279328370.19600656541-0.151110656515-0.3538543482440.890423888407-0.03262963125141.395596374150.125734263538-0.1543026668491.97277227842-0.2732278102381.2072122233173.459588564117.182477463-88.1478429217
493.73217442174-2.20572864559-0.5526703629471.47381132781.07471577214.241471726310.4175471959210.227120097372-0.446001952266-1.03275263753-0.273806339535-0.4212378147410.2159233767290.026987870843-0.004199671993322.880950108830.1479266409-0.04207542033672.00910040411-0.09301515885820.990242897768173.612924117112.663255346-98.6270105276
501.78556328815-1.70968961627-0.1627023710671.72358875806-0.3608126024622.70564047195-0.0884564952009-0.03458436028190.312941916771-0.461256520023-0.275145538540.0497994537207-0.641122623212-0.4224576839590.1376571007881.910080728150.1501851664520.1051521960842.28014849542-0.03789028666251.62736630775171.640316111121.897593265-90.4149632742
514.07546315446-2.715247104160.5283356500424.469241568230.278174171894.983849699380.4235249303070.287676369492-1.04244734917-0.64034231093-0.5597039974020.104143632157-1.055744872910.263100602717-0.01581546940941.344771509730.06167503434330.25505102551.924189051840.1495152667651.29800154655179.387586529119.345153891-86.5497314898
526.343849834973.347265648482.312735694041.99911959105-2.769110089219.360004970630.0533165539475-0.0281370675754-1.167155665-1.255677141380.0736132605287-1.328921783362.10058047284-0.99455482959-0.09747784284812.127498436430.0963921908405-0.08957021805171.27361758452-0.2518412497931.54689556541167.382101681106.760973647-84.947501437
534.864488387290.2780204316740.409308105996.770780730490.4068667633342.759823978010.1462037388340.6080522948720.03687411437091.086000770440.27778972387-0.1874801861290.0618730334314-0.67251714476-0.3491411566611.558061278280.274841493807-0.1467319500961.883865750960.2726807450011.32355097192172.558241543119.9495009-80.8394365718
540.0839541238009-0.062469477528-0.04823958827160.09788606523670.05267318896450.0199591890170.03808215124851.018417343950.9168443281280.3919729734060.5056713340880.634283110803-0.249643222107-0.540737882211-0.4873434411211.808380096-0.01055728436290.1986017316111.78572397954-0.01782479917651.94029303782217.069691434142.965520189-23.3820742438
552.578308058871.69949945614-1.819393902172.58627625333-0.6205813264971.52936119717-0.0767056921113-0.009255850872210.7003745319480.3899892209380.4932782640380.0204363110953-0.194348109719-0.017400587142-0.5014422407961.5738258229-0.07589941708950.463545220731.57092433302-0.3917631140382.50703142242239.221729024145.785230388-22.2633806133
564.11031312058-0.5926588039380.8740218317613.04306062110.2749719070950.247158264864-0.1913535743640.00601611707807-0.3125628056320.0872626223245-0.6255795508060.7592187538630.4371002769680.4046339042360.7103620987291.3735744944-0.1030406485930.2445707948751.97751125528-0.363641932242.64528109056250.481849565145.03512668-23.5146906635
574.9886429397-0.868029772582-2.415293017864.30662931814-1.758262730692.30679276077-0.4314775382640.269797719214-0.2108865116-0.7976686476770.0671209872647-0.4560799804510.1150055694541.10765602670.5131903526051.89371720736-0.1626886972570.5121378090271.61803787874-0.06607500786442.05952111095245.944772332145.47033368-36.6784110536
581.75186260316-1.96540487064-0.4808391206312.38131434184-0.2863168774814.301993625180.6631523144210.307924242623-0.190772770185-0.462698000199-0.01505063408370.3893442925631.17233198271-0.73719361368-0.8724748837022.084917311990.164633135774-0.3002053724192.60127767686-0.08182227240131.87763260027221.736947012127.739154452-37.980042624
593.323660668581.35964387606-1.279807709822.534680286451.88621654153.467088316260.02374927189070.165392182387-0.916078463873-0.1080163255510.2908770660190.0766262554831-0.504444926442-0.468937527629-0.2194699555971.11921599125-0.4258874557610.2396600618421.84726696067-0.08571853422872.15670971873235.107212039136.069967652-30.4563086445
607.00832686057-5.317503013551.926692032492.007714854251.312149758667.654723741890.5676229598233.173114088790.377827879036-0.3758664125430.5679428019280.02341061912441.005541065493.17599373575-0.9258019492462.05826997790.2650669185970.1785606497392.431472155040.03627716103751.32716153579252.784038164130.057299353-26.0429402162
612.25867536684-1.23302593754-0.7507769201061.44503198580.506376561399.53539304287-0.1209431788250.5692001058220.0456170767206-0.269969220703-0.231964203720.0453655566441.357070596531.133462786070.3057874289421.19706439829-0.01652069375130.6300994426921.78701038337-0.2205099735862.16450184449249.672409505136.987776476-32.5807691034
624.255765015221.17607696250.6520373990871.761921992860.6451251401883.495172720650.395372240233-0.5023870457570.02366202384580.138684394727-0.06667165754820.6862079774740.359930755850.264326398040.1753679697971.951985835790.2175377733430.3476085137582.220763236770.06295738794691.54354265551229.076171346127.633756498-42.7093476691
632.13216457277-0.617420308853-0.403209959443.23928201842-2.250256836441.857289077420.649746869524-0.951502981480.469830167812-0.4661907081860.145380090671-0.147437831344-0.1729184312181.5990868318-0.6812564833740.9753468182350.08224978092290.3381367120911.19506711961-0.03353977765740.904726700176140.730833223123.557380268-29.4818448062
645.01864341746-0.3790271642586.46041166524.032816150842.918603190662.02586693589-0.0771650610970.5664195276830.449557538114-1.1528890298-0.2986591801840.679779355122-1.243385085220.4484073766460.4662818003761.282216588780.3088904951530.5376140807241.574074858140.4016059894281.19700269466138.524286331131.981218597-31.8400521097
653.337707751170.1005879268310.1384071172434.82197146099-0.2631595112238.73469820022-0.4079968437920.09219751409610.210884590574-0.02595771384370.209425202670.729931743677-0.190462487023-0.8548197225420.4126162862540.8395554081250.1319145476230.2089235793530.9841711793980.1921434399321.59163420373130.027201259129.991820397-30.8886224658
664.244486978473.095648999121.062056395883.32450601881.684780648732.256960035010.3955017841570.3490477369050.5410668603760.559769877992-0.0599515651985-0.6125153442340.2799030114690.248884427926-0.3240970519381.289296998410.1631935417430.2678342190851.11793448933-0.02978426541281.42950360235144.667245585133.431649732-17.1596593326
675.94784578258-0.166027489358-0.6505628055794.95082861561.015260176876.75043579629-0.0496606171539-0.67739266923-0.2152002266840.811476866120.5959545481511.04130246028-0.2938708689850.431677193569-0.609671776321.122774319360.08738094474860.1556516228181.05450740271-0.005713481259931.41306744542131.492489354109.726571478-18.7148047345
685.938804981231.64757719440.2509059709996.271984450791.007118164517.36229547429-0.1920593848570.125470213548-0.3486054467581.03664409487-0.382779512840.8704590130740.2658598844740.3062611284150.4869200708051.0105412790.1559130314930.3296566478670.875014600320.1325653179911.37582151408128.189016389119.32454116-16.0804910588
692.011569359924.05740283838-0.9289611333583.22745484209-1.274599323554.56462089081-0.00860011027456-0.9186562746680.2414511046150.3952154803240.441304552991-0.119644203352-0.640127465777-0.0467989779162-0.3225898342341.265178664570.2083034047290.08139799506311.194210443450.02992419586861.93401616057121.851539867118.323942622-13.7793790424
706.276795443184.897072603-0.4699761820362.008746963811.913691964632.725644544250.5161803707310.123374778909-0.401440192341-0.144563478631-0.139921732211-1.198469907060.4409820302130.223070727705-0.4404854318550.9532070738960.2327399206570.08714902627241.093367718810.1805392317041.02036353233133.991279541117.963755001-19.2536733034
711.08634789536-2.36513628385-0.6560784474826.590635922920.3394270153251.230588989720.335845507134-0.0292131159848-1.005470982380.59937800418-0.772507074415-1.229166901050.285299417248-0.7690543010420.4179842693321.83244287272-0.412470893337-0.2057742149632.31475917299-0.8195409955732.91305988228235.297879253164.697919554-2.1580122888
726.21686210664.75789300807-3.305865344573.59520556347-2.578720486441.8033350223-0.0303649139530.321845092949-1.012060287460.0933836647758-0.5951777859771.57736817135-0.580035536702-0.01984029684250.5585141302571.91078174001-0.5713713640980.4449996027362.55281219296-1.603974615564.50960013201245.620925625166.175389131-3.4838248005
732.241507464551.933424566913.498795470082.693485397162.287027744075.9943833772-0.792940152074-0.98448491813-0.2265334583490.0599862476133-1.33113253031.148550823360.625054137462-0.7750482859471.835319621331.36032113717-0.1389118814290.3765324664922.11885814235-0.7775789759012.69276928922248.853843904154.473780096-9.15536800438
742.68964885347-3.663435746081.498624095445.5645860142-3.243511396823.32730474542-0.2607763499010.0607204363746-0.00853501908690.0677437395813-0.578334914336-0.0794142301861-0.0933877309898-0.260760985770.6982970898491.96856740531-0.42547611916-0.2359513886362.26515959304-0.1454158526382.5901110099241.936194866166.736759846-17.0868854442
756.73262651851.603837102872.772129171674.850033781160.5207586044053.50131413228-0.06489268677360.5713575946050.6811011353330.555854761258-0.06662270650330.164643630952-0.6283824813741.265906579720.4044271895431.48817325963-0.4917796439070.3165757400892.00317525384-1.07251143013.36182092348239.543152361161.291341679-4.90833688735
761.642358458692.298498506441.915876635164.115123077233.246632421192.56996548451-0.3139876754620.443468914551-0.02112413077590.263111438417-0.3603419974940.511096449531-0.0962647102203-0.08885061901970.5398870173012.1833679772-0.3090697072590.2185081205942.11944648832-0.5331499124852.55299928258231.267312816173.910062527-13.6623938223
772.25162155348-0.2089652818430.02414992181060.9313060458780.5883433567670.3902487033091.140470838850.786885190238-0.769142719577-0.461256949091-0.9405795065540.4905313910050.265462875693-0.0486930268422-0.1317261944471.607421527178.96701589225E-5-0.04406579976261.6259643118-0.5535788896422.40449568531228.071835525160.728624943-13.3564777147
781.794805043560.4671120620410.564247857672.94628635815-2.210232566392.112847341750.701593415392-0.08498268292970.8968969513360.1329082549470.17505796528-0.500231994722-0.2229135382670.586760177092-0.8135540974031.32970347613-0.1235258674120.2669563915992.31518560657-0.7905509891242.03853672574224.348451434137.086316316-2.14241665889
792.495617524185.633191350232.533397056971.996361030525.721925610452.565882271840.02032909908570.1872350470240.590535808634-0.206128209298-0.4922933105060.83881955964-0.27619651242-0.5809767948840.3545163447231.36587763864-0.244703088556-0.2218169478081.65535482922-0.2856698764732.10170740093221.547906812120.041342445-7.41464576684
802.002162202877.61713006932.061991177757.621336743253.784252951712.983734269070.137129491562-0.4604379588170.434959023710.003753871339170.317723036123-0.07434478227650.1082102558570.55176767817-0.425014338281.561121780050.02282821151570.1020853220663.54987585468-1.192592078773.2637104587225.068930195154.60104049327.2450051705
810.0800893681692-0.394134042037-0.4553743708432.028055821222.264450739872.532683026770.1105424270760.8798963481520.2472258395330.3704553119260.345038061534-0.842445948281-1.06839837291-0.183031587322-0.3491208530521.86975094082-0.04163094518590.02400037268392.64401566563-0.9589381353663.2855610146218.18885933164.3559664926.334523302
822.46646729842.00769064806-8.69914774822.010696534881.993631884292.01062930506-4.147464908342.40637395571-3.93215232827-3.824638977462.22216963374-1.756331520312.70589348071-0.9383492033041.80716866713.86561992125-0.7894360904481.198174544391.86628538513-1.178723106912.5726201999225.639487328172.94610727228.4374665354
83-0.0004426868215120.0943001082360.08353609069133.448216457822.945440816882.518779727310.5919321696290.0160868101742-0.0785544634039-0.30890709081-0.8117832896690.973661456546-0.015307841221-0.5946882543550.3953082484462.269194206440.527678359456-0.3109113488482.11530468626-1.662605570572.67718011838228.135269286156.91675603518.7654840909
846.188325165281.02821741987-2.100948821245.09553741414-1.167779183443.45418416362-0.02446026069420.3997123891650.117933238475-0.739008341264-0.2289444148530.3224020103580.303964556025-0.03034043381160.2901574438911.42203311754-0.210153734120.1824001265522.45573019719-0.730752891411.93185723455218.975133191131.05755902212.411987244
851.18113428494-0.582774405892-0.8650538189654.58805510423-0.6604686489520.846488547022-0.05670322597980.5624468368440.2177107013971.284685811890.959305476647-1.43276407764-0.994540327254-0.87812161507-0.8601560964021.823746571280.0336265043502-0.1121395283611.88399810675-0.9688997232662.39477262507221.6888992147.81876949318.7456936892
864.113534189681.29745656651-3.806129189720.475674398354-1.434016940074.37527608927-0.07255406016760.612591086786-0.598035513119-2.527671017771.77582763639-1.34548590929-0.9036910989820.828714243946-1.461818635224.12904238336-0.452604259491.083319568931.84635900845-1.39386070342.79540489063227.603027134171.02774767537.0871907797
870.577682822133-2.22090715942-2.616774143578.500938229442.005148667111.995193198250.4175502036933.10072347139-1.51651088302-1.45505441173-0.6996406577390.820437830228-0.21793790937-0.9976990024240.7713703801092.07451867339-0.1223152787570.1269751279422.79978263358-1.471473920612.05309520067216.906112997159.53401310936.3078652674
88-0.002219284607120.00686289189274-0.00396971071587-0.003096311476770.000130529925087-0.0005304758214740.0742565179739-0.321752179462-0.2975341949560.179831716684-0.09384494590940.4833315857970.137727085421-0.2504942926310.09420813604572.534447430930.6386142550230.1951814027112.3855085775-1.11170395053.03917653227229.1708156.77740564734.6668560521
892.59022454344-1.553380746092.384632941147.514005608531.399076410383.36329615161-0.703823373584-1.05408255209-0.36876123038-0.7038039709640.8141739729560.8689230136620.293517616636-0.6144882738270.1903475288770.985088310144-0.1732800517590.2616045155451.624109393830.03841075545871.23747484651214.24990948119.977304606-75.2029970383
909.289700021660.859090287858-3.378036498269.10104478432-2.36785253012.012925405260.4899485495350.7666634917970.323783894593-0.43707427254-0.6836858950890.188152832833-0.193895599357-0.8663125013720.1090617880631.469085507620.07854155142550.2358918885651.41893558189-0.3840492028781.12802368342211.23463259116.495649912-63.6699821766
912.143043083920.598838114824-2.670117475755.24740562353-0.9557128126647.410995717990.4252681261880.6328651934481.28844085014-0.2699789699890.230838585959-0.133285061418-0.5948906173960.0792357227182-0.7165810137421.496982222970.3247217373450.2724830327381.578120917490.1255210315591.459658395214.315584169115.731584887-74.9165407296
923.020700070472.380231206012.888399084675.64843617059-2.720546899879.387834958440.0676087294109-0.200751692036-0.4582033124560.564759834799-0.152817587751-0.3653301171-0.2415028917430.2238516596120.07892041086811.303043260980.1513978223170.117925107691.64167641455-0.004241943220141.54243867905219.041993987113.783412177-54.6541882425
937.106423557940.2842573835863.071365824828.89867903851-0.1061149546174.57646127680.7497938816840.2933811867020.5643259680650.785243769746-1.59616549397-0.6033228761510.2884336543480.09498924519030.7029142923170.836319778047-0.2429993781880.02133035303711.65279883216-0.1796250923791.85175090861220.673643979121.904036239-62.3652791244
940.00674044782397-0.2551793066410.04591620637246.98634371483-1.075757546280.162139539680.280616501752-1.12363093827-0.7687910854310.0327388102620.2023423653751.07127161864-0.421222918607-0.219279088911-0.3040727041131.70878868961-0.1135249454430.4711383169772.551378055010.8868381114852.31302239754222.184436136124.357388632-76.2734853494
957.10835045154-0.0827638410899-0.06738398441842.032442209930.009839872987242.00758988727-0.6307378823560.2114780298690.5479855841060.189149641641-0.6608713743260.865267916210.348597803839-0.4009316304181.39020475121.25020858872-0.1674227827010.1665184718371.62905572779-0.2053255539311.18054093857207.320289145123.033468634-66.2368338834
961.96998308753-1.85396418076-0.8474005196021.909124090861.570567888974.99639477370.108667349224-0.3795403449710.5159169362290.7585609632010.240777478570.311180373181-0.0706178857496-0.108197651929-0.1611422860411.706862175560.234606186663-0.5534953523021.61231824878-1.538855085611.28610423482211.953002354128.192325143-61.0578572144
972.00948547788-0.8067156899842.920114026557.197537017762.451982506172.01686261734-1.16934403774-0.421868223665-0.396672084085-0.230219029646-0.98407135009-1.75151005233-1.722969498581.312796517071.955970334281.85145122222-0.1727136950.2292556992921.605417761550.2375756223041.6190949711211.279637251130.046116224-69.8353622245
981.21471043856-2.445627793892.572773943899.00919073975-4.223410529915.76682909736-0.05657668987370.660407709116-0.583583823164-0.285695914263-0.365603889180.0283230604768-0.367923718314-0.175917991340.3623826614981.3410609085-0.03213769757420.3425010760861.45493068318-0.1741937819311.36651017273192.462450765113.008142002-62.6349379143
998.58230263924-0.4463982227497.421459563612.775261547081.028092763457.133336083660.294606253379-0.488841680733-0.185666337820.5713040759570.4685222130680.348311329341-0.04454381798590.400406347463-0.6732863993781.72784256436-0.3736814301480.4071772654541.35743836476-0.02881506219851.4686361629194.883948645106.950045504-51.1870717971
1004.1040545595-0.11768520177-2.190372941352.65701692450.3169078729771.64064656163-0.2304229672120.6254383870140.531739373271-0.7866096896590.291699459062-0.4874106635220.113282148547-0.119193909096-0.1316724887611.054617160010.02278597504220.03495373748121.44460327230.1596799424511.06033852428144.94048555299.1196149058-27.3769207329
1017.6236873208-8.595758119657.764170087649.80595203556-8.747369297737.849145944220.524915361565-0.171999856657-0.1448213783240.284057787649-0.3949214093640.3346371439291.123327383491.3020480693-0.1765609981261.708931685420.0730806573552-0.08172372627581.598121901890.107712950851.36017609114153.60830763689.9608368647-14.7011290459
1026.61498041056-4.49844669699-7.825474553076.0204375221-0.6336558783692.020471599320.3054050383490.715637049029-0.588892961243-0.6255495811531.015426089450.9159820606571.05820775713-0.108859160361-0.9704086059541.485505742410.0338417711105-0.1837995245271.38311292237-0.05122315212591.31670672356160.49408278677.46196380641.17823565756
1036.1558290210.4518294924380.1304852364085.503680043490.9650730834835.55227296062-0.4532692868670.7009593493520.672766030923-0.0318816478821-0.1657136250770.03133068015350.6678291047710.6111550903690.6961146159781.061799932140.3082464667430.05359263263231.422976502940.1362473178631.41640916984176.37553207776.45595383484.09847356291
1046.247060688481.618412593360.527535432896.170399978871.032110358127.169396951770.163793200403-0.617591409713-0.6023817569750.3240934036090.390455505039-0.4296914635941.230357718881.66655595044-0.7019374022741.899861382910.16494054106-0.1582767512721.841839502140.3034985315181.24568741826177.92799426773.069707993413.8574709742
1054.410347934012.101750822451.307411541363.317586803941.928106161511.124216611940.213967680190.3132786620560.2658481382410.03266178454630.4480240285730.1404134070080.577033431335-0.15281985509-0.547248648881.508632863370.47928909732-0.03068931701231.425911977210.06434201280721.27576245556170.97390183779.01740518538.66999458867
1062.39891563151-0.4849921049071.703330099641.172273873590.0617072233561.349707992470.1628860890770.242909341031-0.712906332390.266502467436-0.0860378328802-0.807844758237-0.3264793336490.25066224709-0.02439651004951.636393867610.215085613375-0.1772211891951.989005414820.06729222011031.44377505817170.44189114384.258717044725.6710404426
1072.246645758571.80595227263.304404796051.99435075072-2.092914700596.42812749023-0.776943243194-0.5072711808520.1357420719480.1798609451420.4894313398460.9918477498540.952742951894-0.6694075932010.03177414937681.571658177870.3923735062820.4866387475392.047745346610.1644523292082.54876292367274.088728223115.118755754-8.96062899394
1082.774167810691.389413291890.04383345347785.057351216340.3010504056582.383576714510.617107343666-0.8377639023360.889848758973-0.430273822855-0.9687563102190.867641385822-0.1276800708-0.6937828293880.4526893734331.287063093170.25511068847-0.2286649694582.08815484198-0.4563270717392.03099346054272.059665123122.710668415-2.47208372087
1095.271219552141.02447433095-1.303194943161.339472438560.9089118554711.499284932260.2024355709130.346173427230.9524701876370.301426266898-0.242173085598-0.5943534354990.0599586748973-0.1190344916540.05468700157781.38866635120.212261644494-0.1334048303652.34541000697-0.1542437706252.31464013918279.186352489116.8084133562.73669545489
1100.08695401325750.392921007535-0.170829024161.66545731697-0.7408385854840.313397628671-0.536450802868-0.385831162594-0.1043884684220.281131330561-0.181062958263-0.4743482654680.232896848901-0.4862316111650.7612396431081.876727295930.126047349495-0.1615097128392.3639164943-0.6053605474931.83778926527263.450765959101.9129325818.95924866378
1115.63565257282-1.1247948443.353664970682.3572793479-0.7404085591034.20379982583-0.4401002413730.653297010194-0.78168348832-0.0605613056257-0.1822240122470.7093344044130.6480250418-0.252916131980.5535648699371.55827940693-0.1243834204460.1717129903112.14010456598-0.1338898112371.76461947035245.828952467101.52526559.98729155741
1128.319238941453.322270414171.321161816399.095487326380.4268049688626.867460555270.0570119974641-1.398566997810.245391094154-0.463178297562-0.2058292062570.8326782481010.3905623066470.817742928075-0.28819594721.22634616274-0.1775141654180.1404275909682.22119997745-0.6367713044922.03524446921240.952234261101.084012059-3.27490970505
1132.723850979722.052644353291.514390146414.83208076429-0.4504935925091.610662334550.248393122779-0.142917107238-0.2919725924530.366291426423-0.2729745840890.3068889048670.57519137748-0.03848296491290.006709329866992.00524643270.403496643875-0.1469700448182.53541566161-0.5083421087781.79095533082219.457528733116.6835677933.5842233443
1146.59478741044-0.6985776710141.731574963111.97180739621.357542399624.470371249580.07690970568990.058343306304-0.374179929330.457889494064-0.300305746479-0.459102955281-0.0980389495857-0.7073237896580.1794400418991.90264053798-0.117222944545-0.2809306270842.17389986097-0.4076304260711.77972216838225.704392745120.68379678731.8360437289
1152.624513362411.165437168861.122139810624.09612723230.83833410490.655889675629-0.453568982695-3.169346696270.1672089329140.12308942489-0.430913562153-0.2274346669030.4458610213710.7206899222460.6223991845141.50303885222-0.2669777820850.2605236994843.47305035247-0.8217915237421.65270272001222.909072936129.19895232324.023581086
1162.53668186284.181463156380.8930280181587.497610096061.339356838960.343400057354-0.4260107914641.36796343953-0.676706622126-0.1440167521730.6816136734310.01634523158740.150694545950.328558721587-0.274812509191.72111247271-0.6917519771670.07304761903523.72217750037-1.219557036330.896945094407215.820475331127.54045924520.4097169586
1171.267847080280.0994133041528-1.349621414041.174868499421.577547904063.73787899576-0.03609380607440.1229819448880.5085914379610.07580706096440.200728171509-0.7440450832410.8142226450140.287322836813-0.1925944308171.452497939450.1536247388390.1828503069162.16219722547-0.7898597658342.14702590758213.061322156138.74950727518.0266233106
1184.0310036360.834805704325-1.036660579613.29289095640.03140516219450.282730947417-0.09721063425191.000423710390.304712370703-1.374549614040.1907164584310.35237606033-0.3558459052720.8409047850980.0994803835091.602827477290.212285686136-0.02374557951742.059448760520.05768791265040.936597220179137.437566699111.786607719-71.5202132984
1192.03108748275-4.96262699908-2.395094151436.233764866631.511888966874.569379184780.5342365979981.139248325610.15699892851-1.123887635710.0342139866747-0.2213799154930.290084956669-0.591590238235-0.7129624065131.27201300647-0.114471707148-0.102226197021.378707561840.01946917440930.888726587904149.201142242101.471523062-66.5520007864
1202.037458777131.11969543852.377874325767.72521678322-0.03922935658787.371525631910.47212928613-0.333724364725-0.4715940855770.6212996966840.256853527971-0.3587834194270.1970916524190.365027206487-0.917459942711.167259000920.121824621378-0.0749741691581.20537066644-0.04063483764320.962949253859143.503887247101.844438747-56.1393799689
1214.427520495921.312842151990.3323300428158.20487470855-1.200875106468.79085599157-0.808622284220.356667536174-0.692106999869-0.9334943009670.3071458859571.139620061911.62721762213-0.7014407684210.4101184409431.48463174671-0.261254687353-0.106715127551.513899738560.1778583059791.50229513373130.79671447397.0057348222-63.4364428755
1223.115722594140.1132647545451.913647780832.489588666561.587009621415.957001088270.2163892986610.3414249646650.01246020982660.5047536608210.1793534628860.3376894546810.2095065627870.888808582834-0.4895040744271.354627403050.06408978672730.2773220182181.210267638360.02603684916161.53338603374116.38662761376.193137111410.4636862899
1231.94437313497-0.6736597881592.016568333951.88395202685-0.2295792877794.92773349701-0.800022387641-0.4208357034320.4099592013491.054109810520.8204734194021.05285018039-0.3712335390910.3340056994290.002774833042971.708923099690.2078524336350.5722989125831.12318253893-0.1047333320982.4712142981112.85046261284.792409351323.0176856001
1241.2906360041-1.53205868847-0.7901252790222.06818599282-0.262194933869.29579802214-0.1911945265160.176563609120.24338502409-0.525249582150.06590836483070.748988143195-0.5669722624620.03614105132320.1764011639081.268988508820.151094594630.4701476915241.135029970390.3443800752492.43054719111102.15960853480.91504436847.43519281375
1259.04165627949-0.916994997803-1.818568078443.377667994021.366419044424.883981433650.727220078696-0.999288150546-0.562824632998-0.346682341681-0.6209815277850.878427102823-0.676230968175-0.324634210814-0.09722186108951.730921452120.05734053468530.6040948528321.057592623430.05641967552481.58290206138100.17524632175.326495524715.9370236675
1265.58904264129-0.6745370439870.3785701570456.647966979191.590773788538.5935794694-0.369043050271-0.2682894070480.0700562684046-0.498136459408-0.167531788448-0.930129457297-0.236861547116-0.01613277085170.5725155830830.884666823203-0.02631844479740.1290311198950.9067446499480.382631567061.40919497093119.2963111685.3276402093-34.1206147647
1272.633133074162.754367358533.452000130525.642705910823.489063101074.665687213330.297594505596-0.1065186567440.142919391137-0.090722518977-0.3507911473230.182116944376-0.067178974043-0.836829567382-0.04329435289190.9499493532240.03487724948640.194875250671.287788563970.2339260882091.43229917555128.56222412387.1505240074-33.2606492958
1284.500437900410.6067841361770.3933330348955.67860585297-1.213895010912.68472116577-0.210108585969-0.926176675136-0.901381550037-0.7771535524580.5538668427480.2692990648210.390563319781-0.754291273162-0.2459627950081.12110596906-0.00252457804709-0.05974109374811.344599374120.2361788035111.28254825621120.71220907680.4778822655-36.5943963194
1297.384864047960.275176084992-2.653555287342.200620404740.7449517713412.359245271030.43452430605-0.59838421976-0.687100336617-0.515137928586-0.05659045272470.3429060747050.008688495513720.934548451592-0.2381543788811.50491661901-0.0337502322541-0.03049139589161.544473198310.02773369523051.25181385476130.98632928185.7485743592-43.1339408351
1300.624737272650.422264490924-2.097796298412.3329675897-1.863731556127.11596790356-0.3565918496990.724695414546-1.69382101271-0.67377650140.846387581314-0.08272272452150.7603300496840.0459243303483-0.3550259054592.26681200829-0.6817673564730.4446338505631.44412558767-0.3179008806042.08507853106180.295704453140.698468746-63.8739887651
1316.19553414054-0.238081199895-0.716550093925.928322675980.6546093256677.55353669943-0.08073560937540.0714080063629-0.2207858872140.0622733574613-0.830513867237-0.177150216472-0.660105825974-0.05334862533760.8243311578781.761561759680.0785227323070.2027253636931.577046032650.2370293572611.52934409728172.884230664132.603175563-75.6622149175
1326.589282590562.045000387484.036725802389.31927160250.7434463388642.495425906170.143453240607-0.1222683993430.356282875709-0.980300116613-0.350932726359-0.300337783317-1.009625877250.5347648733050.1446524203551.502170414140.1504814678090.5796373882071.666344397260.08905014248311.57574801215181.322453968133.209707325-74.7681248122
1333.64144965153-2.074935395264.659839939355.792355633061.624871341789.985954984550.04780170874760.1668256644170.236211183095-0.321082350480.103375259391-1.22867725012-0.4811553683760.798485991913-0.1165845863551.400831184870.05474707026280.09019375041521.40287317904-0.1999601056891.38375216982186.909338548128.38914984-66.0879165388
1342.329601891940.4398065833042.666761596233.707430877940.8423934169173.103279422470.01324076233-0.6492268028970.825670896866-0.0577593169639-0.448679129568-0.6994190756240.0422993171805-0.1998370984960.3995468883792.066656676590.3066659636130.275882110281.768245694110.2025522696940.92667586422177.888982983134.210397662-60.2278594689
1355.3764379134-0.968903408135-2.218945398852.40338428151.299818931313.151907549530.478796512608-0.3884180298630.593405229011.386993809510.9329309384240.757368782232-1.38538021407-0.813473407465-1.461968200681.645186936110.1968799762860.4763399898641.344875648650.2025550895290.919953852555174.969995964124.002212059-69.6207110878
1368.82248193322-0.1755152231930.7246362892142.19359593275-1.462581210972.909787703680.964865362742-0.1021867467880.6769689331750.5812713633370.570587283381-0.33396436704-1.513525595330.764482161998-1.630597164521.70638306070.2025726567660.3599179329811.80403057982-0.03669870107231.11642944159193.264918625126.057189109-71.3143534406
1371.761922730190.2089242475080.5336075965044.14590285093-2.927812685652.30045745571-0.636221069586-0.009315966303270.2432024099290.596588898955-0.01259773251920.02898800174290.224445068610.4857828100640.4186068642391.660575951290.1073444106390.04980768459222.80135490315-0.3152171754252.49047539359251.093093981111.26951141732.7647410129
1382.174684679741.249892890740.6567538655481.901944550081.228527837270.788306798210.07223789093980.464050530302-0.571968668530.5680759877790.18601889752-0.0228263630296-0.09714834566690.133418928494-0.2159177303222.950854295610.4677079998940.2077734302313.076595841190.09719761845821.83451968957253.48782342593.702889193842.3701931975
1391.729496624860.732047614962-3.311965635984.86087634753-2.21047129746.43292636418-0.2541229206871.224788485190.336568961789-0.317216757739-0.110389195112-0.164129064086-0.423842137904-0.3814128696070.3014440559911.283915328560.398218824773-0.2022995013293.49322490721-0.1760479485941.5882092557245.465863168100.65618204832.1304448357
1407.69849488158-4.205289189772.150399343557.987691816676.929853354442.00195777763-0.148687843447-0.0001208981653210.1174918560280.25001941396-0.0339021371556-0.03298560387530.0260604524140.149250639750.09255331391882.047636151010.350957520584-0.5610777089013.20673577959-0.8960914732792.70470278286257.30235002796.608753081534.0409480632
1410.8696989228270.804898681887-0.8599624542750.969121713078-0.513238178781.211430346790.08103754766260.2036681943440.05477678817180.220138736472-0.295372016454-0.1619499621140.2068432517050.2229057705640.1574748791942.070831488150.9028370740440.4309117193982.88616323708-0.3035599957112.66224492898244.01895928394.056205635430.6367984834
1423.59778691731-0.2068290142040.6857106722482.33952907271-1.021785572492.26090599633-1.317457839320.1051764510070.4455976023640.1053461599160.6769803315820.260175244291-0.464633889295-0.487236189130.5561448670462.084687705140.0036987278191-0.09974021459762.394862548350.07269962393881.60141554694245.10745148795.035678741721.0953320233
1439.556193034411.017883226471.661920445020.1067186316410.1871278058090.2875195594020.139152955408-0.32054613029-0.08033437125271.333675261140.214877950287-0.3563027719280.1027336752820.144784938813-0.246835907331.71227551101-0.1036665072770.19182511861.247343465860.1343042895641.33611411923126.59920736942.95818316687.93913376501
1443.33069271146-0.9395572544553.904075994662.46099804409-0.5800079403094.608423423950.204418356558-0.487754105755-0.417647438462-0.1671486936150.3822602659770.7089280964060.991001069471-0.802087483734-0.4776473267041.52093368798-0.1410456731650.3988631272771.255933930150.2928336944721.75160056748106.29345896543.0233516531-21.591279054
1455.21235513613-0.06407375591471.908009707322.196723305982.163713145636.128425707420.1313508944790.1723692597540.989450486682-0.520798483943-1.42906227634-0.73463024102-0.9821230834281.144579815590.9583186433271.61588320167-0.167999336230.05573009183681.312746404530.6278955295942.0733397538699.390573387850.5959808048-35.2095053209
1460.00714117133964-0.0841071994309-0.05912580806933.19926588035-0.3215234940546.013137164760.05125403101880.109398520452-0.5966083239830.220175210654-0.2452820520711.218392788490.287717887711-1.208679230240.1685768370471.0813249672-0.2586696379450.3577357115923.30750307215-1.070780224072.88408287149251.335231446124.4610612982.54472471943
1471.10648171091-0.869802846761.197534526051.11025120288-0.08792178809383.00602987543-0.2771058290540.52758151131-0.0816810477021-0.6799647142950.04450221716390.0845707148094-0.06801536224890.3081118776670.2618610379912.564296114080.2030450107680.3070125745832.64431525815-1.480850111123.03079624096248.149733966129.4371703274.49345166833
1487.5559536069-0.346525317211-2.491793067130.01696086486420.1185049641190.818353254157-0.110610028341.46197711945-1.4353091754-0.221268943817-0.05354139291790.101445154131-0.302452483833-0.5262682077870.1239501849621.80225379304-0.270736379684-0.09595989826512.17771421536-0.562972452141.62694719674254.876223868133.83028765310.6445612088
Refinement TLS group
IDRefine-IDRefine TLS-IDSelection details
1X-RAY DIFFRACTION1chain 'A' and (resid 5 through 329 )
2X-RAY DIFFRACTION2chain 'A' and (resid 330 through 661 )
3X-RAY DIFFRACTION3chain 'A' and (resid 662 through 907 )
4X-RAY DIFFRACTION4chain 'A' and (resid 908 through 1142 )
5X-RAY DIFFRACTION5chain 'A' and (resid 1143 through 1382 )
6X-RAY DIFFRACTION6chain 'A' and (resid 1383 through 1540 )
7X-RAY DIFFRACTION7chain 'Y' and (resid 1 through 6 )
8X-RAY DIFFRACTION8chain 'Y' and (resid 7 through 20 )
9X-RAY DIFFRACTION9chain 'Y' and (resid 21 through 36 )
10X-RAY DIFFRACTION10chain 'Y' and (resid 37 through 55 )
11X-RAY DIFFRACTION11chain 'Y' and (resid 56 through 64 )
12X-RAY DIFFRACTION12chain 'Y' and (resid 65 through 71 )
13X-RAY DIFFRACTION13chain 'Y' and (resid 72 through 78 )
14X-RAY DIFFRACTION14chain 'Y' and (resid 79 through 84 )
15X-RAY DIFFRACTION15chain 'Z' and (resid 1 through 20 )
16X-RAY DIFFRACTION16chain 'Z' and (resid 21 through 55 )
17X-RAY DIFFRACTION17chain 'Z' and (resid 56 through 84 )
18X-RAY DIFFRACTION18chain 'B' and (resid 5 through 28 )
19X-RAY DIFFRACTION19chain 'B' and (resid 29 through 120 )
20X-RAY DIFFRACTION20chain 'B' and (resid 121 through 136 )
21X-RAY DIFFRACTION21chain 'B' and (resid 137 through 219 )
22X-RAY DIFFRACTION22chain 'B' and (resid 220 through 240 )
23X-RAY DIFFRACTION23chain 'C' and (resid 2 through 28 )
24X-RAY DIFFRACTION24chain 'C' and (resid 29 through 49 )
25X-RAY DIFFRACTION25chain 'C' and (resid 50 through 62 )
26X-RAY DIFFRACTION26chain 'C' and (resid 63 through 93 )
27X-RAY DIFFRACTION27chain 'C' and (resid 94 through 112 )
28X-RAY DIFFRACTION28chain 'C' and (resid 113 through 125 )
29X-RAY DIFFRACTION29chain 'C' and (resid 126 through 171 )
30X-RAY DIFFRACTION30chain 'C' and (resid 172 through 206 )
31X-RAY DIFFRACTION31chain 'D' and (resid 2 through 15 )
32X-RAY DIFFRACTION32chain 'D' and (resid 16 through 35 )
33X-RAY DIFFRACTION33chain 'D' and (resid 36 through 68 )
34X-RAY DIFFRACTION34chain 'D' and (resid 69 through 83 )
35X-RAY DIFFRACTION35chain 'D' and (resid 84 through 148 )
36X-RAY DIFFRACTION36chain 'D' and (resid 149 through 163 )
37X-RAY DIFFRACTION37chain 'D' and (resid 164 through 185 )
38X-RAY DIFFRACTION38chain 'D' and (resid 186 through 199 )
39X-RAY DIFFRACTION39chain 'D' and (resid 200 through 209 )
40X-RAY DIFFRACTION40chain 'E' and (resid 5 through 35 )
41X-RAY DIFFRACTION41chain 'E' and (resid 36 through 50 )
42X-RAY DIFFRACTION42chain 'E' and (resid 51 through 64 )
43X-RAY DIFFRACTION43chain 'E' and (resid 65 through 79 )
44X-RAY DIFFRACTION44chain 'E' and (resid 80 through 103 )
45X-RAY DIFFRACTION45chain 'E' and (resid 104 through 112 )
46X-RAY DIFFRACTION46chain 'E' and (resid 113 through 141 )
47X-RAY DIFFRACTION47chain 'E' and (resid 142 through 155 )
48X-RAY DIFFRACTION48chain 'F' and (resid 1 through 15 )
49X-RAY DIFFRACTION49chain 'F' and (resid 16 through 32 )
50X-RAY DIFFRACTION50chain 'F' and (resid 33 through 47 )
51X-RAY DIFFRACTION51chain 'F' and (resid 48 through 67 )
52X-RAY DIFFRACTION52chain 'F' and (resid 68 through 80 )
53X-RAY DIFFRACTION53chain 'F' and (resid 81 through 100 )
54X-RAY DIFFRACTION54chain 'G' and (resid 2 through 11 )
55X-RAY DIFFRACTION55chain 'G' and (resid 12 through 35 )
56X-RAY DIFFRACTION56chain 'G' and (resid 36 through 52 )
57X-RAY DIFFRACTION57chain 'G' and (resid 53 through 69 )
58X-RAY DIFFRACTION58chain 'G' and (resid 70 through 92 )
59X-RAY DIFFRACTION59chain 'G' and (resid 93 through 109 )
60X-RAY DIFFRACTION60chain 'G' and (resid 110 through 115 )
61X-RAY DIFFRACTION61chain 'G' and (resid 116 through 129 )
62X-RAY DIFFRACTION62chain 'G' and (resid 130 through 156 )
63X-RAY DIFFRACTION63chain 'H' and (resid 2 through 19 )
64X-RAY DIFFRACTION64chain 'H' and (resid 20 through 29 )
65X-RAY DIFFRACTION65chain 'H' and (resid 30 through 63 )
66X-RAY DIFFRACTION66chain 'H' and (resid 64 through 85 )
67X-RAY DIFFRACTION67chain 'H' and (resid 86 through 102 )
68X-RAY DIFFRACTION68chain 'H' and (resid 103 through 119 )
69X-RAY DIFFRACTION69chain 'H' and (resid 120 through 130 )
70X-RAY DIFFRACTION70chain 'H' and (resid 131 through 138 )
71X-RAY DIFFRACTION71chain 'I' and (resid 2 through 12 )
72X-RAY DIFFRACTION72chain 'I' and (resid 13 through 32 )
73X-RAY DIFFRACTION73chain 'I' and (resid 33 through 42 )
74X-RAY DIFFRACTION74chain 'I' and (resid 43 through 58 )
75X-RAY DIFFRACTION75chain 'I' and (resid 59 through 84 )
76X-RAY DIFFRACTION76chain 'I' and (resid 85 through 96 )
77X-RAY DIFFRACTION77chain 'I' and (resid 97 through 106 )
78X-RAY DIFFRACTION78chain 'I' and (resid 107 through 121 )
79X-RAY DIFFRACTION79chain 'I' and (resid 122 through 127 )
80X-RAY DIFFRACTION80chain 'J' and (resid 5 through 12 )
81X-RAY DIFFRACTION81chain 'J' and (resid 13 through 28 )
82X-RAY DIFFRACTION82chain 'J' and (resid 29 through 37 )
83X-RAY DIFFRACTION83chain 'J' and (resid 38 through 42 )
84X-RAY DIFFRACTION84chain 'J' and (resid 43 through 60 )
85X-RAY DIFFRACTION85chain 'J' and (resid 61 through 72 )
86X-RAY DIFFRACTION86chain 'J' and (resid 73 through 84 )
87X-RAY DIFFRACTION87chain 'J' and (resid 85 through 94 )
88X-RAY DIFFRACTION88chain 'J' and (resid 95 through 100 )
89X-RAY DIFFRACTION89chain 'K' and (resid 11 through 23 )
90X-RAY DIFFRACTION90chain 'K' and (resid 24 through 34 )
91X-RAY DIFFRACTION91chain 'K' and (resid 35 through 43 )
92X-RAY DIFFRACTION92chain 'K' and (resid 44 through 57 )
93X-RAY DIFFRACTION93chain 'K' and (resid 58 through 72 )
94X-RAY DIFFRACTION94chain 'K' and (resid 73 through 78 )
95X-RAY DIFFRACTION95chain 'K' and (resid 79 through 90 )
96X-RAY DIFFRACTION96chain 'K' and (resid 91 through 99 )
97X-RAY DIFFRACTION97chain 'K' and (resid 100 through 110 )
98X-RAY DIFFRACTION98chain 'K' and (resid 111 through 120 )
99X-RAY DIFFRACTION99chain 'K' and (resid 121 through 126 )
100X-RAY DIFFRACTION100chain 'L' and (resid 5 through 12 )
101X-RAY DIFFRACTION101chain 'L' and (resid 13 through 22 )
102X-RAY DIFFRACTION102chain 'L' and (resid 23 through 32 )
103X-RAY DIFFRACTION103chain 'L' and (resid 33 through 69 )
104X-RAY DIFFRACTION104chain 'L' and (resid 70 through 81 )
105X-RAY DIFFRACTION105chain 'L' and (resid 82 through 110 )
106X-RAY DIFFRACTION106chain 'L' and (resid 111 through 126 )
107X-RAY DIFFRACTION107chain 'M' and (resid 2 through 14 )
108X-RAY DIFFRACTION108chain 'M' and (resid 15 through 49 )
109X-RAY DIFFRACTION109chain 'M' and (resid 50 through 66 )
110X-RAY DIFFRACTION110chain 'M' and (resid 67 through 81 )
111X-RAY DIFFRACTION111chain 'M' and (resid 82 through 107 )
112X-RAY DIFFRACTION112chain 'M' and (resid 108 through 117 )
113X-RAY DIFFRACTION113chain 'N' and (resid 2 through 11 )
114X-RAY DIFFRACTION114chain 'N' and (resid 12 through 29 )
115X-RAY DIFFRACTION115chain 'N' and (resid 30 through 39 )
116X-RAY DIFFRACTION116chain 'N' and (resid 40 through 44 )
117X-RAY DIFFRACTION117chain 'N' and (resid 45 through 61 )
118X-RAY DIFFRACTION118chain 'O' and (resid 2 through 24 )
119X-RAY DIFFRACTION119chain 'O' and (resid 25 through 49 )
120X-RAY DIFFRACTION120chain 'O' and (resid 50 through 73 )
121X-RAY DIFFRACTION121chain 'O' and (resid 74 through 88 )
122X-RAY DIFFRACTION122chain 'P' and (resid 1 through 36 )
123X-RAY DIFFRACTION123chain 'P' and (resid 37 through 48 )
124X-RAY DIFFRACTION124chain 'P' and (resid 49 through 62 )
125X-RAY DIFFRACTION125chain 'P' and (resid 63 through 84 )
126X-RAY DIFFRACTION126chain 'Q' and (resid 2 through 12 )
127X-RAY DIFFRACTION127chain 'Q' and (resid 13 through 34 )
128X-RAY DIFFRACTION128chain 'Q' and (resid 35 through 70 )
129X-RAY DIFFRACTION129chain 'Q' and (resid 71 through 101 )
130X-RAY DIFFRACTION130chain 'R' and (resid 19 through 24 )
131X-RAY DIFFRACTION131chain 'R' and (resid 25 through 36 )
132X-RAY DIFFRACTION132chain 'R' and (resid 37 through 43 )
133X-RAY DIFFRACTION133chain 'R' and (resid 44 through 52 )
134X-RAY DIFFRACTION134chain 'R' and (resid 53 through 59 )
135X-RAY DIFFRACTION135chain 'R' and (resid 60 through 76 )
136X-RAY DIFFRACTION136chain 'R' and (resid 77 through 88 )
137X-RAY DIFFRACTION137chain 'S' and (resid 2 through 15 )
138X-RAY DIFFRACTION138chain 'S' and (resid 16 through 30 )
139X-RAY DIFFRACTION139chain 'S' and (resid 31 through 41 )
140X-RAY DIFFRACTION140chain 'S' and (resid 42 through 47 )
141X-RAY DIFFRACTION141chain 'S' and (resid 48 through 52 )
142X-RAY DIFFRACTION142chain 'S' and (resid 53 through 85 )
143X-RAY DIFFRACTION143chain 'T' and (resid 8 through 12 )
144X-RAY DIFFRACTION144chain 'T' and (resid 13 through 75 )
145X-RAY DIFFRACTION145chain 'T' and (resid 76 through 106 )
146X-RAY DIFFRACTION146chain 'U' and (resid 2 through 8 )
147X-RAY DIFFRACTION147chain 'U' and (resid 9 through 15 )
148X-RAY DIFFRACTION148chain 'U' and (resid 16 through 26 )

+
About Yorodumi

-
News

-
Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

  • Version 3 of the EMDB header file is now the official format.
  • The previous official version 1.9 will be removed from the archive.

Related info.:EMDB header

External links:wwPDB to switch to version 3 of the EMDB data model

-
Aug 12, 2020. Covid-19 info

Covid-19 info

URL: https://pdbj.org/emnavi/covid19.php

New page: Covid-19 featured information page in EM Navigator.

Related info.:Covid-19 info / Mar 5, 2020. Novel coronavirus structure data

+
Mar 5, 2020. Novel coronavirus structure data

Novel coronavirus structure data

Related info.:Yorodumi Speices / Aug 12, 2020. Covid-19 info

External links:COVID-19 featured content - PDBj / Molecule of the Month (242)：Coronavirus Proteases

+
Jan 31, 2019. EMDB accession codes are about to change! (news from PDBe EMDB page)

EMDB accession codes are about to change! (news from PDBe EMDB page)

  • The allocation of 4 digits for EMDB accession codes will soon come to an end. Whilst these codes will remain in use, new EMDB accession codes will include an additional digit and will expand incrementally as the available range of codes is exhausted. The current 4-digit format prefixed with “EMD-” (i.e. EMD-XXXX) will advance to a 5-digit format (i.e. EMD-XXXXX), and so on. It is currently estimated that the 4-digit codes will be depleted around Spring 2019, at which point the 5-digit format will come into force.
  • The EM Navigator/Yorodumi systems omit the EMD- prefix.

Related info.:Q: What is EMD? / ID/Accession-code notation in Yorodumi/EM Navigator

External links:EMDB Accession Codes are Changing Soon! / Contact to PDBj

+
Jul 12, 2017. Major update of PDB

Major update of PDB

  • wwPDB released updated PDB data conforming to the new PDBx/mmCIF dictionary.
  • This is a major update changing the version number from 4 to 5, and with Remediation, in which all the entries are updated.
  • In this update, many items about electron microscopy experimental information are reorganized (e.g. em_software).
  • Now, EM Navigator and Yorodumi are based on the updated data.

External links:wwPDB Remediation / Enriched Model Files Conforming to OneDep Data Standards Now Available in the PDB FTP Archive

-
Yorodumi

Thousand views of thousand structures

  • Yorodumi is a browser for structure data from EMDB, PDB, SASBDB, etc.
  • This page is also the successor to EM Navigator detail page, and also detail information page/front-end page for Omokage search.
  • The word "yorodu" (or yorozu) is an old Japanese word meaning "ten thousand". "mi" (miru) is to see.

Related info.:EMDB / PDB / SASBDB / Comparison of 3 databanks / Yorodumi Search / Aug 31, 2016. New EM Navigator & Yorodumi / Yorodumi Papers / Jmol/JSmol / Function and homology information / Changes in new EM Navigator and Yorodumi

Read more