登録情報 | データベース: PDB / ID: 6ldb |
---|
タイトル | Structure of Bifidobacterium dentium beta-glucuronidase complexed with uronic isofagomine |
---|
要素 | LacZ1 Beta-galactosidase |
---|
キーワード | HYDROLASE / inhibitor / glycosidase / isofagomine |
---|
機能・相同性 | 機能・相同性情報
: / beta-glucuronidase / beta-glucuronidase activity / beta-galactosidase activity / carbohydrate binding / carbohydrate metabolic process / signaling receptor binding / extracellular space類似検索 - 分子機能 Glycoside hydrolase, family 2, active site / Glycosyl hydrolases family 2 acid/base catalyst. / Glycoside hydrolase, family 2, conserved site / Glycosyl hydrolases family 2 signature 1. / Glycoside hydrolase, family 2 / Glycoside hydrolase family 2, catalytic domain / Glycosyl hydrolases family 2, TIM barrel domain / Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich / Glycosyl hydrolases family 2, sugar binding domain / Glycosyl hydrolases family 2 ...Glycoside hydrolase, family 2, active site / Glycosyl hydrolases family 2 acid/base catalyst. / Glycoside hydrolase, family 2, conserved site / Glycosyl hydrolases family 2 signature 1. / Glycoside hydrolase, family 2 / Glycoside hydrolase family 2, catalytic domain / Glycosyl hydrolases family 2, TIM barrel domain / Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich / Glycosyl hydrolases family 2, sugar binding domain / Glycosyl hydrolases family 2 / Glycosyl hydrolases family 2, sugar binding domain / Beta-Galactosidase/glucuronidase domain superfamily / Galactose-binding-like domain superfamily / Glycoside hydrolase superfamily / Immunoglobulin-like fold類似検索 - ドメイン・相同性 |
---|
生物種 | Bifidobacterium dentium (バクテリア) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.651 Å |
---|
データ登録者 | Lin, H.-Y. / Hsieh, T.-J. / Lin, C.-H. |
---|
資金援助 | 台湾, 1件 組織 | 認可番号 | 国 |
---|
Ministry of Science and Technology (Taiwan) | 108-2113-M-001-001 | 台湾 |
|
---|
引用 | ジャーナル: Commun Biol / 年: 2021 タイトル: Entropy-driven binding of gut bacterial beta-glucuronidase inhibitors ameliorates irinotecan-induced toxicity. 著者: Lin, H.Y. / Chen, C.Y. / Lin, T.C. / Yeh, L.F. / Hsieh, W.C. / Gao, S. / Burnouf, P.A. / Chen, B.M. / Hsieh, T.J. / Dashnyam, P. / Kuo, Y.H. / Tu, Z. / Roffler, S.R. / Lin, C.H. |
---|
履歴 | 登録 | 2019年11月20日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
---|
改定 1.0 | 2021年1月27日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2021年8月11日 | Group: Database references / カテゴリ: citation / citation_author / database_2 Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
---|
改定 1.2 | 2023年11月22日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
---|
|
---|