登録情報 | データベース: PDB / ID: 6iw8 |
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タイトル | Crystal structure of Importin-alpha and wild-type GM130 |
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要素 | - Importin subunit alpha-1
- Peptide from Golgin subfamily A member 2
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キーワード | PROTEIN BINDING / Importin alpha / GM130 |
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機能・相同性 | 機能・相同性情報
meiotic spindle assembly / Golgi cis cisterna / positive regulation of protein glycosylation / Golgi disassembly / asymmetric cell division / Golgi ribbon formation / Sensing of DNA Double Strand Breaks / entry of viral genome into host nucleus through nuclear pore complex via importin / positive regulation of viral life cycle / microtubule nucleation ...meiotic spindle assembly / Golgi cis cisterna / positive regulation of protein glycosylation / Golgi disassembly / asymmetric cell division / Golgi ribbon formation / Sensing of DNA Double Strand Breaks / entry of viral genome into host nucleus through nuclear pore complex via importin / positive regulation of viral life cycle / microtubule nucleation / importin-alpha family protein binding / NLS-dependent protein nuclear import complex / cis-Golgi network / postsynapse to nucleus signaling pathway / Golgi Cisternae Pericentriolar Stack Reorganization / centrosome cycle / COPII-mediated vesicle transport / syntaxin binding / nuclear import signal receptor activity / nuclear localization sequence binding / Golgi cisterna membrane / NLS-bearing protein import into nucleus / Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models / protein glycosylation / COPII-coated ER to Golgi transport vesicle / Golgi organization / mitotic spindle assembly / spindle assembly / endoplasmic reticulum to Golgi vesicle-mediated transport / COPI-mediated anterograde transport / endoplasmic reticulum-Golgi intermediate compartment membrane / negative regulation of autophagy / negative regulation of protein binding / mitotic spindle / spindle pole / cytoplasmic stress granule / protein import into nucleus / host cell / protein transport / microtubule binding / protein homotetramerization / DNA-binding transcription factor binding / microtubule / postsynaptic density / cadherin binding / Golgi membrane / glutamatergic synapse / protein kinase binding / Golgi apparatus / nucleoplasm / identical protein binding / nucleus / cytosol類似検索 - 分子機能 Golgin subfamily A / Golgin subfamily A member 2, C-terminal binding motif / Golgin subfamily A, conserved domain / Putative golgin subfamily A member 2-like protein 5 / GM130 C-terminal binding motif / Importin subunit alpha / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain superfamily / Importin beta binding domain / Atypical Arm repeat ...Golgin subfamily A / Golgin subfamily A member 2, C-terminal binding motif / Golgin subfamily A, conserved domain / Putative golgin subfamily A member 2-like protein 5 / GM130 C-terminal binding motif / Importin subunit alpha / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain superfamily / Importin beta binding domain / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain / IBB domain profile. / Armadillo/plakoglobin ARM repeat profile. / Armadillo/beta-catenin-like repeat / Armadillo/beta-catenin-like repeats / Armadillo / Leucine-rich Repeat Variant / Leucine-rich Repeat Variant / Armadillo-like helical / Alpha Horseshoe / Armadillo-type fold / Mainly Alpha類似検索 - ドメイン・相同性 Importin subunit alpha-1 / Golgin subfamily A member 2類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.8 Å |
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データ登録者 | Chang, C.-C. / Chen, C.-J. / Pien, Y.-C. / Tsai, S.-Y. / Hsia, K.-C. |
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資金援助 | 台湾, 1件 組織 | 認可番号 | 国 |
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Ministry of Science and Technology (Taiwan) | 106-2311-B-001 -038 -MY3 | 台湾 |
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引用 | ジャーナル: Nat Commun / 年: 2019 タイトル: Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha. 著者: Chang, C.-C. / Chen, C.-J. / Grauffel, C. / Pien, Y.-C. / Lim, C. / Tsai, S.-Y. / Hsia, K.-C. |
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履歴 | 登録 | 2018年12月4日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2019年10月2日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年11月22日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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