登録情報 | データベース: PDB / ID: 6b9h |
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タイトル | Complex of Hook Domain with a Dynein Light Intermediate Chain Peptide |
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要素 | - Cytoplasmic dynein 1 light intermediate chain 1
- Protein Hook homolog 3
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キーワード | PROTEIN TRANSPORT/Motor protein / Dynein / Dynactin / Effector / Hook / Light Intermediate Chain (LIC) / PROTEIN TRANSPORT-Motor protein complex |
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機能・相同性 | 機能・相同性情報
FHF complex / interkinetic nuclear migration / early endosome to recycling endosome transport / protein localization to perinuclear region of cytoplasm / microtubule anchoring at centrosome / Golgi localization / positive regulation of mitotic cell cycle spindle assembly checkpoint / dynein light chain binding / dynein heavy chain binding / neuronal stem cell population maintenance ...FHF complex / interkinetic nuclear migration / early endosome to recycling endosome transport / protein localization to perinuclear region of cytoplasm / microtubule anchoring at centrosome / Golgi localization / positive regulation of mitotic cell cycle spindle assembly checkpoint / dynein light chain binding / dynein heavy chain binding / neuronal stem cell population maintenance / endosome organization / regulation of vesicle-mediated transport / cytoskeleton-dependent intracellular transport / early endosome to late endosome transport / COPI-independent Golgi-to-ER retrograde traffic / cis-Golgi network / dynein light intermediate chain binding / cytoplasmic dynein complex / protein localization to centrosome / dynein intermediate chain binding / lysosome organization / pericentriolar material / endosome to lysosome transport / microtubule-based movement / dynactin binding / ficolin-1-rich granule membrane / centriolar satellite / Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal / COPI-mediated anterograde transport / Mitotic Prometaphase / cytoplasmic microtubule organization / EML4 and NUDC in mitotic spindle formation / Resolution of Sister Chromatid Cohesion / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / MHC class II antigen presentation / secretory granule membrane / RHO GTPases Activate Formins / kinetochore / negative regulation of neurogenesis / spindle pole / Aggrephagy / microtubule cytoskeleton organization / HCMV Early Events / recycling endosome membrane / Separation of Sister Chromatids / GDP binding / endocytic vesicle membrane / protein transport / protein-macromolecule adaptor activity / microtubule binding / microtubule / molecular adaptor activity / cell cycle / cell division / centrosome / Neutrophil degranulation / RNA binding / ATP binding / identical protein binding / membrane / plasma membrane / cytoplasm / cytosol類似検索 - 分子機能 Hook, C-terminal / HOOK protein coiled-coil region / HOOK, N-terminal / HOOK domain / Dynein 1 light intermediate chain / Dynein family light intermediate chain / Dynein light intermediate chain (DLIC) / Calponin-like domain / Actin-binding Protein, T-fimbrin; domain 1 / Calponin homology domain ...Hook, C-terminal / HOOK protein coiled-coil region / HOOK, N-terminal / HOOK domain / Dynein 1 light intermediate chain / Dynein family light intermediate chain / Dynein light intermediate chain (DLIC) / Calponin-like domain / Actin-binding Protein, T-fimbrin; domain 1 / Calponin homology domain / CH domain superfamily / Calponin homology (CH) domain profile. / P-loop containing nucleoside triphosphate hydrolase / Orthogonal Bundle / Mainly Alpha類似検索 - ドメイン・相同性 Protein Hook homolog 3 / Cytoplasmic dynein 1 light intermediate chain 1類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.5 Å |
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データ登録者 | Lee, I.G. / Dominguez, R. |
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資金援助 | 米国, 1件 組織 | 認可番号 | 国 |
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National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | P01 GM087253 | 米国 |
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引用 | ジャーナル: Nat Commun / 年: 2018 タイトル: A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity. 著者: Lee, I.G. / Olenick, M.A. / Boczkowska, M. / Franzini-Armstrong, C. / Holzbaur, E.L.F. / Dominguez, R. |
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履歴 | 登録 | 2017年10月10日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2018年3月21日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2020年1月1日 | Group: Author supporting evidence / カテゴリ: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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改定 1.2 | 2023年10月4日 | Group: Advisory / Data collection ...Advisory / Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_unobs_or_zero_occ_atoms Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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