登録情報 データベース : PDB / ID : 5y31 構造の表示 ダウンロードとリンクタイトル Crystal structure of human LGI1-ADAM22 complex 要素Disintegrin and metalloproteinase domain-containing protein 22 Leucine-rich glioma-inactivated protein 1 詳細キーワード CELL ADHESION / epilepsy / synapse / ADAM / EPTP / WD40機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
LGI-ADAM interactions / axon initial segment / negative regulation of cell adhesion / neurotransmitter receptor localization to postsynaptic specialization membrane / positive regulation of synaptic transmission / synaptic cleft / central nervous system development / axon guidance / postsynaptic density membrane / metalloendopeptidase activity ... LGI-ADAM interactions / axon initial segment / negative regulation of cell adhesion / neurotransmitter receptor localization to postsynaptic specialization membrane / positive regulation of synaptic transmission / synaptic cleft / central nervous system development / axon guidance / postsynaptic density membrane / metalloendopeptidase activity / integrin binding / neuron projection development / nervous system development / positive regulation of cell growth / cell adhesion / axon / signaling receptor binding / glutamatergic synapse / dendrite / Golgi apparatus / endoplasmic reticulum / proteolysis / extracellular space / extracellular region / membrane / plasma membrane / cytoplasm 類似検索 - 分子機能 : / Leucine-rich glioma-inactivated , EPTP repeat / EAR / EPTP domain / EAR repeat profile. / ADAM cysteine-rich / ADAM, cysteine-rich domain / ADAM Cysteine-Rich Domain / Disintegrin, conserved site / Disintegrins signature. ... : / Leucine-rich glioma-inactivated , EPTP repeat / EAR / EPTP domain / EAR repeat profile. / ADAM cysteine-rich / ADAM, cysteine-rich domain / ADAM Cysteine-Rich Domain / Disintegrin, conserved site / Disintegrins signature. / Peptidase M12B, propeptide / Reprolysin family propeptide / Reprolysin domain, adamalysin-type / Reprolysin (M12B) family zinc metalloprotease / Disintegrin / Disintegrin domain profile. / Homologues of snake disintegrins / Disintegrin domain / Disintegrin domain superfamily / Peptidase M12B, ADAM/reprolysin / ADAM type metalloprotease domain profile. / EGF-like domain, extracellular / EGF-like domain / Cysteine-rich flanking region, C-terminal / Leucine rich repeat C-terminal domain / Metallopeptidase, catalytic domain superfamily / Leucine rich repeat / Leucine-rich repeat, typical subtype / Leucine-rich repeats, typical (most populated) subfamily / EGF-like domain signature 1. / Leucine-rich repeat / EGF-like domain / Leucine-rich repeat domain superfamily 類似検索 - ドメイン・相同性 Leucine-rich glioma-inactivated protein 1 / Disintegrin and metalloproteinase domain-containing protein 22 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 7.125 Å 詳細データ登録者 Yamagata, A. / Fukai, S. 引用ジャーナル : Nat Commun / 年 : 2018タイトル : Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.著者 : Yamagata, A. / Miyazaki, Y. / Yokoi, N. / Shigematsu, H. / Sato, Y. / Goto-Ito, S. / Maeda, A. / Goto, T. / Sanbo, M. / Hirabayashi, M. / Shirouzu, M. / Fukata, Y. / Fukata, M. / Fukai, S. 履歴 登録 2017年7月27日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2018年5月2日 Provider : repository / タイプ : Initial release改定 1.1 2018年11月7日 Group : Data collection / Structure summary / カテゴリ : struct / Item : _struct.title改定 1.2 2020年7月29日 Group : Data collection / Derived calculations / Structure summaryカテゴリ : chem_comp / entity ... chem_comp / entity / pdbx_chem_comp_identifier / pdbx_entity_nonpoly / struct_conn / struct_conn_type / struct_site / struct_site_gen Item : _chem_comp.name / _chem_comp.type ... _chem_comp.name / _chem_comp.type / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _struct_conn.conn_type_id / _struct_conn.id / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.pdbx_role / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn_type.id 解説 : Carbohydrate remediation / Provider : repository / タイプ : Remediation
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