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Structure paper

TitleStructural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.
Journal, issue, pagesNat Commun, Vol. 9, Page 1546-1546, Year 2018
Publish dateJul 27, 2017 (structure data deposition date)
AuthorsYamagata, A. / Miyazaki, Y. / Yokoi, N. / Shigematsu, H. / Sato, Y. / Goto-Ito, S. / Maeda, A. / Goto, T. / Sanbo, M. / Hirabayashi, M. ...Yamagata, A. / Miyazaki, Y. / Yokoi, N. / Shigematsu, H. / Sato, Y. / Goto-Ito, S. / Maeda, A. / Goto, T. / Sanbo, M. / Hirabayashi, M. / Shirouzu, M. / Fukata, Y. / Fukata, M. / Fukai, S.
External linksNat Commun / PubMed:29670100
MethodsX-ray diffraction
Resolution1.781 - 7.125 Å
Structure data

PDB-5y2z:
Crystal structure of human LGI1 EPTP-ADAM22 complex
Method: X-RAY DIFFRACTION / Resolution: 2.67 Å

PDB-5y30:
Crystal structure of LGI1 LRR domain
Method: X-RAY DIFFRACTION / Resolution: 1.781 Å

PDB-5y31:
Crystal structure of human LGI1-ADAM22 complex
Method: X-RAY DIFFRACTION / Resolution: 7.125 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL ADHESION / epilepsy / synapse / ADAM / EPTP / WD40

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