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Yorodumi- PDB-5y1z: Crystal structure of ZMYND8 PHD-BROMO-PWWP tandem in complex with... -
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-Basic information
Entry | Database: PDB / ID: 5y1z | ||||||
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Title | Crystal structure of ZMYND8 PHD-BROMO-PWWP tandem in complex with Drebrin ADF-H domain | ||||||
Components |
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Keywords | TRANSCRIPTION / NUCLEAR PROTEIN / PROTEIN BINDING / ACTIN BINDING | ||||||
Function / homology | Function and homology information positive regulation of receptor localization to synapse / regulation of postsynaptic density protein 95 clustering / cell communication by chemical coupling / cell communication by electrical coupling / site of polarized growth / regulation of dendrite development / cytoplasmic sequestering of protein / postsynaptic actin cytoskeleton organization / maintenance of protein location in cell / profilin binding ...positive regulation of receptor localization to synapse / regulation of postsynaptic density protein 95 clustering / cell communication by chemical coupling / cell communication by electrical coupling / site of polarized growth / regulation of dendrite development / cytoplasmic sequestering of protein / postsynaptic actin cytoskeleton organization / maintenance of protein location in cell / profilin binding / positive regulation of synaptic plasticity / positive regulation of dendritic spine morphogenesis / regulation of actin filament polymerization / actomyosin / gap junction / neural precursor cell proliferation / RHOD GTPase cycle / RHOBTB1 GTPase cycle / positive regulation of filopodium assembly / postsynaptic cytosol / cortical actin cytoskeleton / positive regulation of dendritic spine development / cortical cytoskeleton / regulation of neuronal synaptic plasticity / modulation of excitatory postsynaptic potential / site of DNA damage / RHOH GTPase cycle / positive regulation of dendritic spine maintenance / positive regulation of axon extension / RHOBTB2 GTPase cycle / positive regulation of transcription elongation by RNA polymerase II / neuron projection morphogenesis / protein localization to chromatin / lysine-acetylated histone binding / methylated histone binding / negative regulation of cell migration / dendritic shaft / actin filament organization / double-strand break repair via homologous recombination / actin filament binding / transcription corepressor activity / actin cytoskeleton / chromatin organization / lamellipodium / nervous system development / actin binding / growth cone / DNA-binding transcription factor binding / postsynaptic membrane / in utero embryonic development / dendritic spine / postsynaptic density / cytoskeleton / cadherin binding / protein domain specific binding / glutamatergic synapse / dendrite / chromatin / nucleolus / negative regulation of transcription by RNA polymerase II / zinc ion binding / nucleoplasm / nucleus / cytoplasm Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.676 Å | ||||||
Authors | Yao, N. / Li, J. / Liu, H. / Wan, J. / Liu, W. / Zhang, M. | ||||||
Citation | Journal: Structure / Year: 2017 Title: The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin Authors: Yao, N. / Li, J. / Liu, H. / Wan, J. / Liu, W. / Zhang, M. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 5y1z.cif.gz | 355.2 KB | Display | PDBx/mmCIF format |
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PDB format | pdb5y1z.ent.gz | 288 KB | Display | PDB format |
PDBx/mmJSON format | 5y1z.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 5y1z_validation.pdf.gz | 480.2 KB | Display | wwPDB validaton report |
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Full document | 5y1z_full_validation.pdf.gz | 486.5 KB | Display | |
Data in XML | 5y1z_validation.xml.gz | 31.5 KB | Display | |
Data in CIF | 5y1z_validation.cif.gz | 43.5 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/y1/5y1z ftp://data.pdbj.org/pub/pdb/validation_reports/y1/5y1z | HTTPS FTP |
-Related structure data
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-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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