登録情報 | データベース: PDB / ID: 5w7i |
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タイトル | X-ray structure of ankyrin repeat domain of DHHC17 in complex with Snap25b peptide |
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要素 | - Palmitoyltransferase ZDHHC17
- Snap25b-111-120
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キーワード | PROTEIN BINDING / Palmitoyltransferases / Snap25 / ankyrin repeat domain |
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機能・相同性 | 機能・相同性情報
regulation of neurotrophin TRK receptor signaling pathway / protein-cysteine S-myristoyltransferase activity / protein-cysteine S-stearoyltransferase activity / Toxicity of botulinum toxin type C (botC) / protein S-acyltransferase / protein palmitoylation / protein-cysteine S-palmitoyltransferase activity / neurotransmitter uptake / Toxicity of botulinum toxin type E (botE) / exocytic insertion of neurotransmitter receptor to postsynaptic membrane ...regulation of neurotrophin TRK receptor signaling pathway / protein-cysteine S-myristoyltransferase activity / protein-cysteine S-stearoyltransferase activity / Toxicity of botulinum toxin type C (botC) / protein S-acyltransferase / protein palmitoylation / protein-cysteine S-palmitoyltransferase activity / neurotransmitter uptake / Toxicity of botulinum toxin type E (botE) / exocytic insertion of neurotransmitter receptor to postsynaptic membrane / extrinsic component of presynaptic membrane / Acetylcholine Neurotransmitter Release Cycle / synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex / synaptobrevin 2-SNAP-25-syntaxin-1a complex / Toxicity of botulinum toxin type A (botA) / synaptic vesicle fusion to presynaptic active zone membrane / synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex / Serotonin Neurotransmitter Release Cycle / GABA synthesis, release, reuptake and degradation / presynaptic dense core vesicle exocytosis / palmitoyltransferase activity / ribbon synapse / synaptic vesicle docking / Dopamine Neurotransmitter Release Cycle / Norepinephrine Neurotransmitter Release Cycle / regulation of programmed cell death / SNARE complex / SNAP receptor activity / Glutamate Neurotransmitter Release Cycle / Golgi-associated vesicle membrane / neurotransmitter receptor internalization / Sensory processing of sound by inner hair cells of the cochlea / syntaxin-1 binding / SNARE complex assembly / synaptic vesicle priming / lipoprotein transport / endosomal transport / regulation of synapse assembly / Other interleukin signaling / myosin binding / regulation of neuron projection development / exocytosis / voltage-gated potassium channel activity / synaptic vesicle exocytosis / associative learning / regulation of insulin secretion / tertiary granule membrane / long-term memory / axonal growth cone / specific granule membrane / presynaptic active zone membrane / voltage-gated potassium channel complex / 転移酵素; アシル基を移すもの; アミノアシル基以外のアシル基を移すもの / photoreceptor inner segment / regulation of ERK1 and ERK2 cascade / axonogenesis / filopodium / locomotory behavior / cell projection / Regulation of insulin secretion / long-term synaptic potentiation / trans-Golgi network / positive regulation of insulin secretion / calcium-dependent protein binding / actin cytoskeleton / synaptic vesicle / lamellipodium / presynaptic membrane / cell cortex / growth cone / chemical synaptic transmission / positive regulation of canonical NF-kappaB signal transduction / transmembrane transporter binding / postsynapse / cytoskeleton / endosome / neuron projection / protein domain specific binding / Golgi membrane / intracellular membrane-bounded organelle / signaling receptor binding / neuronal cell body / lipid binding / glutamatergic synapse / Neutrophil degranulation / perinuclear region of cytoplasm / Golgi apparatus / identical protein binding / membrane / plasma membrane / cytosol / cytoplasm類似検索 - 分子機能 Palmitoyltransferase, DHHC domain / DHHC palmitoyltransferase / DHHC domain profile. / Synaptosomal-associated protein 25 / SNAP-25 domain / SNAP-25 family / Helical region found in SNAREs / t-SNARE coiled-coil homology domain profile. / Target SNARE coiled-coil homology domain / Ankyrin repeat-containing domain ...Palmitoyltransferase, DHHC domain / DHHC palmitoyltransferase / DHHC domain profile. / Synaptosomal-associated protein 25 / SNAP-25 domain / SNAP-25 family / Helical region found in SNAREs / t-SNARE coiled-coil homology domain profile. / Target SNARE coiled-coil homology domain / Ankyrin repeat-containing domain / Ankyrin repeats (3 copies) / Ankyrin repeat profile. / Ankyrin repeat region circular profile. / ankyrin repeats / Ankyrin repeat / Ankyrin repeat-containing domain superfamily / Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat / Alpha Horseshoe / Mainly Alpha類似検索 - ドメイン・相同性 Synaptosomal-associated protein 25 / Palmitoyltransferase ZDHHC17類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.105 Å |
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データ登録者 | Verardi, R. / Kim, J.-S. / Ghirlando, R. / Banerjee, A. |
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資金援助 | 米国, 1件 組織 | 認可番号 | 国 |
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National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health & Human Development (NIH/NICHD) | 1ZIAHD008928 | 米国 |
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引用 | |
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履歴 | 登録 | 2017年6月20日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2017年8月9日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2017年8月16日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _citation_author.name |
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改定 1.2 | 2017年9月20日 | Group: Database references / カテゴリ: citation Item: _citation.journal_volume / _citation.page_first / _citation.page_last |
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改定 1.3 | 2019年12月11日 | Group: Author supporting evidence / カテゴリ: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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改定 1.4 | 2023年10月4日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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