登録情報 データベース : PDB / ID : 5vpf 構造の表示 ダウンロードとリンクタイトル Transcription factor FosB/JunD bZIP domain in complex with cognate DNA, type-II crystal 要素DNA (5'-D(*CP*GP*TP*CP*GP*GP*TP*GP*AP*CP*TP*CP*AP*CP*CP*GP*AP*CP*G)-3')DNA (5'-D(*CP*GP*TP*CP*GP*GP*TP*GP*AP*GP*TP*CP*AP*CP*CP*GP*AP*CP*G)-3')Protein fosB Transcription factor jun-D 詳細キーワード transcription/dna / activator protein-1 / basic leucine zipper / bZIP / fos / jun / transcription factor / DNA-binding protein / redox switch / coiled-coil / transcription-dna complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
transcription factor AP-1 complex / NGF-stimulated transcription / osteoblast development / response to steroid hormone / response to morphine / response to corticosterone / behavioral response to cocaine / positive regulation of osteoblast differentiation / cellular response to hormone stimulus / response to mechanical stimulus ... transcription factor AP-1 complex / NGF-stimulated transcription / osteoblast development / response to steroid hormone / response to morphine / response to corticosterone / behavioral response to cocaine / positive regulation of osteoblast differentiation / cellular response to hormone stimulus / response to mechanical stimulus / response to cAMP / transcription repressor complex / response to amphetamine / cellular response to calcium ion / transcription coregulator binding / response to progesterone / female pregnancy / response to nicotine / RNA polymerase II transcription regulator complex / sequence-specific double-stranded DNA binding / regulation of cell population proliferation / DNA-binding transcription activator activity, RNA polymerase II-specific / gene expression / transcription regulator complex / Estrogen-dependent gene expression / response to ethanol / transcription by RNA polymerase II / DNA-binding transcription factor activity, RNA polymerase II-specific / transcription cis-regulatory region binding / regulation of cell cycle / RNA polymerase II cis-regulatory region sequence-specific DNA binding / response to xenobiotic stimulus / intracellular membrane-bounded organelle / regulation of transcription by RNA polymerase II / chromatin / enzyme binding / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / DNA binding / nucleoplasm / nucleus / cytosol 類似検索 - 分子機能 AP-1 transcription factor / Transcription factor Jun / Jun-like transcription factor / Jun-like transcription factor / bZIP transcription factor / Transcription factor, Skn-1-like, DNA-binding domain superfamily / : / Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #170 / Basic-leucine zipper (bZIP) domain signature. / Basic-leucine zipper (bZIP) domain profile. ... AP-1 transcription factor / Transcription factor Jun / Jun-like transcription factor / Jun-like transcription factor / bZIP transcription factor / Transcription factor, Skn-1-like, DNA-binding domain superfamily / : / Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #170 / Basic-leucine zipper (bZIP) domain signature. / Basic-leucine zipper (bZIP) domain profile. / basic region leucin zipper / Basic-leucine zipper domain / Basic-leucine zipper domain superfamily / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Up-down Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 PHOSPHATE ION / DNA / DNA (> 10) / Transcription factor JunD / Protein FosB 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.694 Å 詳細データ登録者 Yin, Z. / Rudenko, G. / Machius, M. 資金援助 米国, 2件 詳細 詳細を隠す組織 認可番号 国 National Institutes of Health/National Institute on Drug Abuse (NIH/NIDA) R01 DA040621 米国 Brain and Behavior Research Foundation 米国
引用ジャーナル : Nucleic Acids Res. / 年 : 2017タイトル : Activator Protein-1: redox switch controlling structure and DNA-binding.著者 : Yin, Z. / Machius, M. / Nestler, E.J. / Rudenko, G. 履歴 登録 2017年5月4日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2017年9月6日 Provider : repository / タイプ : Initial release改定 1.1 2017年10月18日 Group : Database references / カテゴリ : citationItem : _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title改定 1.2 2017年11月15日 Group : Database references / カテゴリ : citationItem : _citation.journal_volume / _citation.page_first / _citation.page_last改定 1.3 2019年12月11日 Group : Author supporting evidence / カテゴリ : pdbx_audit_support / Item : _pdbx_audit_support.funding_organization改定 1.4 2023年10月4日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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