Structural Analysis of Glucocorticoid Receptor beta Ligand Binding Domain Complexed with Glucocorticoid Antagonist RU-486: Implication of Helix 12 in Antagonism
Components
Glucocorticoid receptor
Keywords
HORMONE RECEPTOR / Nuclear receptor
Function / homology
Function and homology information
regulation of glucocorticoid biosynthetic process / nuclear glucocorticoid receptor activity / steroid hormone binding / glucocorticoid metabolic process / neuroinflammatory response / mammary gland duct morphogenesis / microglia differentiation / astrocyte differentiation / maternal behavior / motor behavior ...regulation of glucocorticoid biosynthetic process / nuclear glucocorticoid receptor activity / steroid hormone binding / glucocorticoid metabolic process / neuroinflammatory response / mammary gland duct morphogenesis / microglia differentiation / astrocyte differentiation / maternal behavior / motor behavior / adrenal gland development / regulation of gluconeogenesis / estrogen response element binding / core promoter sequence-specific DNA binding / cellular response to transforming growth factor beta stimulus / TBP-class protein binding / cellular response to dexamethasone stimulus / synaptic transmission, glutamatergic / Hsp90 protein binding / positive regulation of miRNA transcription / spindle / DNA-binding transcription repressor activity, RNA polymerase II-specific / nuclear receptor activity / positive regulation of neuron apoptotic process / chromatin organization / DNA-binding transcription activator activity, RNA polymerase II-specific / gene expression / nuclear speck / centrosome / synapse / protein kinase binding / protein-containing complex / mitochondrion / zinc ion binding / identical protein binding / membrane / cytosol Similarity search - Function
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