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- PDB-5oph: G-quadruplex structure of DNA oligonucleotide containing GGGGCC r... -
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Open data
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Basic information
Entry | Database: PDB / ID: 5oph | ||||||||||||||||||||||||||||
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Title | G-quadruplex structure of DNA oligonucleotide containing GGGGCC repeats linked to ALS and FTD | ||||||||||||||||||||||||||||
![]() | DNA (5'-D(*![]() DNA / G-quadruplex / Nucelar Magnetic Resonance / K+ solution / Antiparallel / Four G-quartets / Edgewise loops / Stacking / GGGGCC-repat / ALS and FTD / Neurodegenerative disorders / Repetitive Sequences / Nucleic Acid / 8Br-dG / modified residue | Function / homology | DNA / DNA (> 10) | ![]() Biological species | ![]() Method | SOLUTION NMR / simulated annealing | ![]() Brcic, J. / Plavec, J. | Funding support | | ![]()
![]() ![]() Title: NMR structure of a G-quadruplex formed by four d(G4C2) repeats: insights into structural polymorphism. Authors: Brcic, J. / Plavec, J. History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 141.7 KB | Display | ![]() |
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PDB format | ![]() | 115.7 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
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-Validation report
Summary document | ![]() | 325.9 KB | Display | ![]() |
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Full document | ![]() | 379.3 KB | Display | |
Data in XML | ![]() | 6.5 KB | Display | |
Data in CIF | ![]() | 10 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data | |
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: DNA chain | Mass: 7036.323 Da / Num. of mol.: 1 / Source method: obtained synthetically / Source: (synth.) ![]() |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
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NMR experiment |
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Sample preparation
Details |
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Sample |
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Sample conditions | Ionic strength: 53 mM / Label: 298 K / pH: 5.8 / Pressure: 1 bar / Temperature: 298 K |
-NMR measurement
NMR spectrometer |
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Processing
NMR software |
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Refinement | Method: simulated annealing / Software ordinal: 2 | ||||||||||||||||||||||||
NMR representative | Selection criteria: closest to the average | ||||||||||||||||||||||||
NMR ensemble | Conformer selection criteria: structures with the least restraint violations Conformers calculated total number: 100 / Conformers submitted total number: 10 |