Entry | Database: PDB / ID: 5o0w |
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Title | Crystal structure of the complex between Nb474 and Trypanosoma congolense fructose-1,6-bisphosphate aldolase |
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Components | - Fructose-bisphosphate aldolase
- Nb474
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Keywords | LYASE / complex / Nanobody / aldolase / diagnosis |
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Function / homology | Function and homology information
Fructose-bisphosphate aldolase class-I active site / Fructose-bisphosphate aldolase class-I active site. / Fructose-bisphosphate aldolase, class-I / Fructose-bisphosphate aldolase class-I / Aldolase class I / Aldolase-type TIM barrel / TIM Barrel / Alpha-Beta Barrel / Alpha BetaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_eukaryote.gif) Trypanosoma congolense (eukaryote)
![](img/tx_mammal.gif) Vicugna pacos (alpaca) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.57 Å |
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Authors | Pinto, J. / Magez, S. / Sterckx, Y. |
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Funding support | Belgium, 2items Organization | Grant number | Country |
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VUB | VUB-SRP3 | Belgium | IUAP | | Belgium |
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Citation | Journal: PLoS Negl Trop Dis / Year: 2017 Title: Structural basis for the high specificity of a Trypanosoma congolense immunoassay targeting glycosomal aldolase. Authors: Pinto, J. / Odongo, S. / Lee, F. / Gaspariunaite, V. / Muyldermans, S. / Magez, S. / Sterckx, Y.G. |
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History | Deposition | May 17, 2017 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Sep 27, 2017 | Provider: repository / Type: Initial release |
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Revision 1.1 | Aug 14, 2019 | Group: Data collection / Category: reflns / reflns_shell Item: _reflns.pdbx_Rrim_I_all / _reflns_shell.pdbx_Rrim_I_all |
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Revision 1.2 | Jan 17, 2024 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id |
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