登録情報 データベース : PDB / ID : 5b4y 構造の表示 ダウンロードとリンクタイトル Crystal structure of the LA12 fragment of ApoER2 要素Low-density lipoprotein receptor-related protein 8 詳細 キーワード SIGNALING PROTEIN / signal transduction機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
ammon gyrus development / reelin receptor activity / positive regulation of CREB transcription factor activity / ventral spinal cord development / very-low-density lipoprotein particle receptor activity / reelin-mediated signaling pathway / high-density lipoprotein particle binding / low-density lipoprotein particle receptor activity / layer formation in cerebral cortex / cellular response to cholesterol ... ammon gyrus development / reelin receptor activity / positive regulation of CREB transcription factor activity / ventral spinal cord development / very-low-density lipoprotein particle receptor activity / reelin-mediated signaling pathway / high-density lipoprotein particle binding / low-density lipoprotein particle receptor activity / layer formation in cerebral cortex / cellular response to cholesterol / positive regulation of dendritic spine morphogenesis / positive regulation of dendrite development / dendrite morphogenesis / cargo receptor activity / retinoid metabolic process / microtubule associated complex / Platelet sensitization by LDL / regulation of innate immune response / kinesin binding / apolipoprotein binding / positive regulation of protein tyrosine kinase activity / Retinoid metabolism and transport / caveola / modulation of chemical synaptic transmission / lipid metabolic process / cellular response to growth factor stimulus / cytokine-mediated signaling pathway / endocytosis / transmembrane signaling receptor activity / calcium-dependent protein binding / positive regulation of peptidyl-tyrosine phosphorylation / amyloid-beta binding / chemical synaptic transmission / regulation of apoptotic process / receptor complex / response to xenobiotic stimulus / axon / neuronal cell body / synapse / calcium ion binding / dendrite / cell surface / signal transduction / proteolysis / extracellular space / membrane / plasma membrane 類似検索 - 分子機能 Low-density lipoprotein receptor repeat class B / LDL-receptor class B (LDLRB) repeat profile. / LDLR class B repeat / Low-density lipoprotein-receptor YWTD domain / Low-density lipoprotein receptor domain class A / : / Low-density lipoprotein (LDL) receptor class A, conserved site / LDL-receptor class A (LDLRA) domain signature. / LDL-receptor class A (LDLRA) domain profile. / Calcium-binding EGF domain ... Low-density lipoprotein receptor repeat class B / LDL-receptor class B (LDLRB) repeat profile. / LDLR class B repeat / Low-density lipoprotein-receptor YWTD domain / Low-density lipoprotein receptor domain class A / : / Low-density lipoprotein (LDL) receptor class A, conserved site / LDL-receptor class A (LDLRA) domain signature. / LDL-receptor class A (LDLRA) domain profile. / Calcium-binding EGF domain / Low-density lipoprotein receptor domain class A / Low-density lipoprotein (LDL) receptor class A repeat / LDL receptor-like superfamily / Six-bladed beta-propeller, TolB-like / Coagulation Factor Xa inhibitory site / EGF-type aspartate/asparagine hydroxylation site / EGF-like calcium-binding, conserved site / Calcium-binding EGF-like domain signature. / Aspartic acid and asparagine hydroxylation site. / EGF-like calcium-binding domain / Calcium-binding EGF-like domain / Epidermal growth factor-like domain. / EGF-like domain profile. / EGF-like domain signature 2. / EGF-like domain 類似検索 - ドメイン・相同性 Low-density lipoprotein receptor-related protein 8 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.9 Å 詳細データ登録者 Nogi, T. / Tabata, S. / Hirai, H. / Yasui, N. / Takagi, J. 引用ジャーナル : To Be Published タイトル : Crystal structure of the ectodomain from a LDLR close homologue in complex with its physiological ligand.著者 : Hirai, H. / Yasui, N. / Yamashita, K. / Tabata, S. / Yamamoto, M. / Takagi, J. / Nogi, T. 履歴 登録 2016年4月20日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2017年4月26日 Provider : repository / タイプ : Initial release改定 1.1 2020年2月26日 Group : Data collection / カテゴリ : diffrn_source / Item : _diffrn_source.pdbx_synchrotron_site改定 1.2 2023年11月8日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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