登録情報 データベース : PDB / ID : 4xpc 構造の表示 ダウンロードとリンクタイトル Crystal structure of 5'- CTTATAAATTTATAAG in a host-guest complex 要素DNA (5'-D(*CP*TP*TP*AP*TP*AP*AP*A)-3')DNA (5'-D(P*TP*TP*TP*AP*TP*AP*AP*G)-3')reverse transcriptase 詳細キーワード TRANSFERASE/DNA / host-guest complex B-DNA non-natural nucleobase pair synthetic biology / TRANSFERASE-DNA complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
retroviral 3' processing activity / host cell late endosome membrane / DNA catabolic process / 加水分解酵素; プロテアーゼ; ペプチド結合加水分解酵素; アスパラギン酸プロテアーゼ / ribonuclease H / virion assembly / protein-DNA complex / host multivesicular body / viral genome integration into host DNA / RNA-directed DNA polymerase ... retroviral 3' processing activity / host cell late endosome membrane / DNA catabolic process / 加水分解酵素; プロテアーゼ; ペプチド結合加水分解酵素; アスパラギン酸プロテアーゼ / ribonuclease H / virion assembly / protein-DNA complex / host multivesicular body / viral genome integration into host DNA / RNA-directed DNA polymerase / establishment of integrated proviral latency / symbiont-mediated suppression of host gene expression / RNA-directed DNA polymerase activity / RNA-DNA hybrid ribonuclease activity / 転移酵素; リンを含む基を移すもの; 核酸を移すもの / viral nucleocapsid / aspartic-type endopeptidase activity / DNA recombination / structural constituent of virion / DNA-directed DNA polymerase / 加水分解酵素; エステル加水分解酵素 / DNA-directed DNA polymerase activity / symbiont entry into host cell / host cell plasma membrane / proteolysis / DNA binding / RNA binding / zinc ion binding / membrane 類似検索 - 分子機能 Gag-Pol polyprotein, Zinc-finger like domain / Murine leukemia virus integrase, C-terminal / Zinc-finger like, probable DNA-binding / Murine leukemia virus (MLV) integrase (IN) C-terminal domain / Gamma-retroviral matrix protein / Gag polyprotein, inner coat protein p12 / Core shell protein Gag P30 / : / Matrix protein (MA), p15 / Gag polyprotein, inner coat protein p12 ... Gag-Pol polyprotein, Zinc-finger like domain / Murine leukemia virus integrase, C-terminal / Zinc-finger like, probable DNA-binding / Murine leukemia virus (MLV) integrase (IN) C-terminal domain / Gamma-retroviral matrix protein / Gag polyprotein, inner coat protein p12 / Core shell protein Gag P30 / : / Matrix protein (MA), p15 / Gag polyprotein, inner coat protein p12 / Gag P30 core shell protein / Gamma-retroviral matrix domain superfamily / Reverse transcriptase/retrotransposon-derived protein, RNase H-like domain / RNase H-like domain found in reverse transcriptase / HIV Type 1 Reverse Transcriptase, subunit A, domain 1 / HIV Type 1 Reverse Transcriptase; Chain A, domain 1 / Reverse transcriptase/Diguanylate cyclase domain / RNase H / Integrase core domain / Integrase, catalytic core / Integrase catalytic domain profile. / Ribonuclease H domain / RNase H type-1 domain profile. / Reverse transcriptase (RNA-dependent DNA polymerase) / Reverse transcriptase domain / Reverse transcriptase (RT) catalytic domain profile. / Retropepsins / Retroviral aspartyl protease / Aspartyl protease, retroviral-type family profile. / Peptidase A2A, retrovirus, catalytic / Retroviral matrix protein / Retrovirus capsid, N-terminal / zinc finger / Zinc knuckle / Zinc finger, CCHC-type superfamily / Zinc finger, CCHC-type / Zinc finger CCHC-type profile. / Aspartic peptidase, active site / Eukaryotic and viral aspartyl proteases active site. / Aspartic peptidase domain superfamily / Ribonuclease H superfamily / Ribonuclease H-like superfamily / Reverse transcriptase/Diguanylate cyclase domain / Alpha-Beta Plaits / Roll / DNA/RNA polymerase superfamily / 2-Layer Sandwich / Alpha Beta 類似検索 - ドメイン・相同性生物種 Moloney murine leukemia virus (ウイルス)synthetic construct (人工物) 手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.68 Å 詳細データ登録者 Georgiadis, M.M. / Singh, I. 資金援助 米国, 1件 詳細 詳細を隠す組織 認可番号 国 National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) R01GM111386 米国
引用ジャーナル : J. Am. Chem. Soc. / 年 : 2015タイトル : Structural basis for a six nucleotide genetic alphabet.著者 : Georgiadis, M.M. / Singh, I. / Kellett, W.F. / Hoshika, S. / Benner, S.A. / Richards, N.G. 履歴 登録 2015年1月16日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2015年5月27日 Provider : repository / タイプ : Initial release改定 1.1 2017年1月11日 Group : Database references改定 1.2 2017年9月20日 Group : Author supporting evidence / Refinement description / カテゴリ : pdbx_audit_support / software / Item : _pdbx_audit_support.funding_organization改定 1.3 2019年12月25日 Group : Author supporting evidence / Derived calculations / カテゴリ : pdbx_audit_support / struct_connItem : _pdbx_audit_support.funding_organization / _struct_conn.pdbx_leaving_atom_flag改定 1.4 2024年2月28日 Group : Data collection / Database references / カテゴリ : chem_comp_atom / chem_comp_bond / database_2Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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