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Structure paper

TitleStructural basis for a six nucleotide genetic alphabet.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 137, Page 6947-6955, Year 2015
Publish dateJan 15, 2015 (structure data deposition date)
AuthorsGeorgiadis, M.M. / Singh, I. / Kellett, W.F. / Hoshika, S. / Benner, S.A. / Richards, N.G.
External linksJ. Am. Chem. Soc. / PubMed:25961938
MethodsX-ray diffraction
Resolution1.68 - 1.985 Å
Structure data

PDB-4xno:
Crystal structure of 5'-CTTATPPPZZZATAAG
Method: X-RAY DIFFRACTION / Resolution: 1.985 Å

PDB-4xo0:
Crystal structure of 5'-CTTATPPTAZZATAAG in a host-guest complex
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-4xpc:
Crystal structure of 5'- CTTATAAATTTATAAG in a host-guest complex
Method: X-RAY DIFFRACTION / Resolution: 1.68 Å

PDB-4xpe:
Crystal structure of 5'-CTTATGGGCCCATAAG in a host-guest complex
Method: X-RAY DIFFRACTION / Resolution: 1.78 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • synthetic construct (others)
  • moloney murine leukemia virus (isolate shinnick)
KeywordsDNA / A-form DNA / non-natural nucleobase pair / synthetic biology / TRANSFERASE/DNA / host-guest complex / B-DNA / TRANSFERASE-DNA complex / host-guest complex B-DNA non-natural nucleobase pair synthetic biology

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