登録情報 データベース : PDB / ID : 4u15 構造の表示 ダウンロードとリンクタイトル M3-mT4L receptor bound to tiotropium 要素Muscarinic acetylcholine receptor M3,Lysozyme,Muscarinic acetylcholine receptor M3 詳細 キーワード MEMBRANE PROTEIN/INHIBITOR / GPCR T4L Stabillized Crystallography / MEMBRANE PROTEIN / MEMBRANE PROTEIN-INHIBITOR complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
negative regulation of heart rate by acetylcholine / G protein-coupled acetylcholine receptor binding / Muscarinic acetylcholine receptors / saliva secretion / quaternary ammonium group binding / ion channel modulating, G protein-coupled receptor signaling pathway / phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway / response to acetylcholine / G protein-coupled acetylcholine receptor activity / positive regulation of vascular associated smooth muscle contraction ... negative regulation of heart rate by acetylcholine / G protein-coupled acetylcholine receptor binding / Muscarinic acetylcholine receptors / saliva secretion / quaternary ammonium group binding / ion channel modulating, G protein-coupled receptor signaling pathway / phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway / response to acetylcholine / G protein-coupled acetylcholine receptor activity / positive regulation of vascular associated smooth muscle contraction / regulation of smooth muscle contraction / adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway / positive regulation of smooth muscle contraction / G protein-coupled serotonin receptor activity / synaptic transmission, cholinergic / acetylcholine binding / G alpha (q) signalling events / acetylcholine receptor signaling pathway / ligand-gated ion channel signaling pathway / G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger / smooth muscle contraction / asymmetric synapse / axon terminus / viral release from host cell by cytolysis / positive regulation of vasoconstriction / peptidoglycan catabolic process / basal plasma membrane / calcium-mediated signaling / postsynaptic density membrane / positive regulation of insulin secretion / G protein-coupled acetylcholine receptor signaling pathway / cell wall macromolecule catabolic process / lysozyme / lysozyme activity / presynaptic membrane / chemical synaptic transmission / basolateral plasma membrane / host cell cytoplasm / defense response to bacterium / glutamatergic synapse / synapse / dendrite / endoplasmic reticulum membrane / plasma membrane 類似検索 - 分子機能 Muscarinic acetylcholine receptor M3 / Muscarinic acetylcholine receptor family / Endolysin T4 type / : / T4-type lysozyme / Glycoside hydrolase, family 24 / Lysozyme domain superfamily / Phage lysozyme / Serpentine type 7TM GPCR chemoreceptor Srsx / G-protein coupled receptors family 1 signature. ... Muscarinic acetylcholine receptor M3 / Muscarinic acetylcholine receptor family / Endolysin T4 type / : / T4-type lysozyme / Glycoside hydrolase, family 24 / Lysozyme domain superfamily / Phage lysozyme / Serpentine type 7TM GPCR chemoreceptor Srsx / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM / G-protein coupled receptors family 1 profile. / 7 transmembrane receptor (rhodopsin family) / Lysozyme-like domain superfamily 類似検索 - ドメイン・相同性 Chem-0HK / (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate / D(-)-TARTARIC ACID / Endolysin / Muscarinic acetylcholine receptor M3 類似検索 - 構成要素生物種 Rattus norvegicus (ドブネズミ) Enterobacteria phage T4 (ファージ)手法 X線回折 / シンクロトロン / 解像度 : 2.8 Å 詳細データ登録者 Thorsen, T.S. / Matt, R. / Weis, W.I. / Kobilka, B. 資金援助 デンマーク, 1件 詳細 詳細を隠す組織 認可番号 国 Benzon foundation デンマーク
引用ジャーナル : Structure / 年 : 2014タイトル : Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis.著者 : Thorsen, T.S. / Matt, R. / Weis, W.I. / Kobilka, B.K. 履歴 登録 2014年7月15日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2014年11月26日 Provider : repository / タイプ : Initial release改定 1.1 2014年12月24日 Group : Database references改定 1.2 2017年11月22日 Group : Database references / Derived calculations ... Database references / Derived calculations / Other / Refinement description / Source and taxonomy カテゴリ : citation / entity_src_gen ... citation / entity_src_gen / pdbx_database_status / pdbx_struct_oper_list / software Item : _citation.journal_id_CSD / _entity_src_gen.pdbx_alt_source_flag ... _citation.journal_id_CSD / _entity_src_gen.pdbx_alt_source_flag / _pdbx_database_status.pdb_format_compatible / _pdbx_struct_oper_list.symmetry_operation 改定 1.3 2023年12月27日 Group : Data collection / Database references / カテゴリ : chem_comp_atom / chem_comp_bond / database_2Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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