Entry Database : PDB / ID : 4nuf Structure visualization Downloads & linksTitle Crystal Structure of SHP/EID1 ComponentsEID1 peptide Maltose ABC transporter periplasmic protein, Nuclear receptor subfamily 0 group B member 2 chimeric construct DetailsKeywords TRANSCRIPTION / protein-peptide complex / peptide mimicking protein helix / sandwich fold / transport proteinFunction / homology Function and homology informationFunction Domain/homology Component
histone acetyltransferase regulator activity / Nuclear Receptor transcription pathway / nuclear retinoic acid receptor binding / bile acid and bile salt transport / peroxisome proliferator activated receptor binding / transcription regulator inhibitor activity / cell cycle / nuclear thyroid hormone receptor binding / histone acetyltransferase binding / detection of maltose stimulus ... histone acetyltransferase regulator activity / Nuclear Receptor transcription pathway / nuclear retinoic acid receptor binding / bile acid and bile salt transport / peroxisome proliferator activated receptor binding / transcription regulator inhibitor activity / cell cycle / nuclear thyroid hormone receptor binding / histone acetyltransferase binding / detection of maltose stimulus / maltose transport complex / regulation of cell differentiation / carbohydrate transport / nuclear retinoid X receptor binding / carbohydrate transmembrane transporter activity / maltose binding / maltose transport / maltodextrin transmembrane transport / animal organ regeneration / response to glucose / ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing / Notch signaling pathway / ATP-binding cassette (ABC) transporter complex / cell chemotaxis / circadian regulation of gene expression / circadian rhythm / positive regulation of insulin secretion / negative regulation of DNA-binding transcription factor activity / response to organic cyclic compound / cytoplasmic ribonucleoprotein granule / transcription corepressor activity / outer membrane-bounded periplasmic space / response to ethanol / cell differentiation / periplasmic space / protein domain specific binding / negative regulation of gene expression / negative regulation of DNA-templated transcription / DNA damage response / positive regulation of gene expression / positive regulation of DNA-templated transcription / chromatin / protein-containing complex binding / negative regulation of transcription by RNA polymerase II / protein homodimerization activity / protein-containing complex / nucleoplasm / membrane / nucleus / cytoplasm Similarity search - Function EP300-interacting inhibitor of differentiation 1 / EP300-interacting inhibitor of differentiation / Nuclear receptor subfamily 0 group B member 1/2 / Maltose/Cyclodextrin ABC transporter, substrate-binding protein / Solute-binding family 1, conserved site / Bacterial extracellular solute-binding proteins, family 1 signature. / Bacterial extracellular solute-binding protein / Bacterial extracellular solute-binding protein / Retinoid X Receptor / Retinoid X Receptor ... EP300-interacting inhibitor of differentiation 1 / EP300-interacting inhibitor of differentiation / Nuclear receptor subfamily 0 group B member 1/2 / Maltose/Cyclodextrin ABC transporter, substrate-binding protein / Solute-binding family 1, conserved site / Bacterial extracellular solute-binding proteins, family 1 signature. / Bacterial extracellular solute-binding protein / Bacterial extracellular solute-binding protein / Retinoid X Receptor / Retinoid X Receptor / Nuclear hormone receptor / Nuclear hormone receptor, ligand-binding domain / Nuclear hormone receptor-like domain superfamily / Nuclear receptor (NR) ligand-binding (LBD) domain profile. / Ligand binding domain of hormone receptors / Ligand-binding domain of nuclear hormone receptor / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homology alpha-maltose / : / Maltose/maltodextrin-binding periplasmic protein / Nuclear receptor subfamily 0 group B member 2 / EP300-interacting inhibitor of differentiation 1 Similarity search - ComponentBiological species Escherichia coli O104:H4 (bacteria)mus musculus (house mouse)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution : 2.8 Å DetailsAuthors Zhi, X. / Zhou, X.E. / He, Y. / Zechner, C. / Suino-Powell, K.M. / Kliewer, S.A. / Melcher, K. / Mangelsdorf, D.J. / Xu, H.E. CitationJournal : Proc.Natl.Acad.Sci.USA / Year : 2014Title : Structural insights into gene repression by the orphan nuclear receptor SHP.Authors : Zhi, X. / Zhou, X.E. / He, Y. / Zechner, C. / Suino-Powell, K.M. / Kliewer, S.A. / Melcher, K. / Mangelsdorf, D.J. / Xu, H.E. History Deposition Dec 3, 2013 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Jan 29, 2014 Provider : repository / Type : Initial releaseRevision 1.1 Aug 9, 2017 Group : Refinement description / Source and taxonomy / Category : entity_src_gen / softwareRevision 2.0 Jul 29, 2020 Group : Atomic model / Data collection ... Atomic model / Data collection / Database references / Derived calculations / Non-polymer description / Structure summary Category : atom_site / chem_comp ... atom_site / chem_comp / entity / entity_name_com / pdbx_branch_scheme / pdbx_chem_comp_identifier / pdbx_entity_branch / pdbx_entity_branch_descriptor / pdbx_entity_branch_link / pdbx_entity_branch_list / pdbx_entity_nonpoly / pdbx_molecule_features / pdbx_nonpoly_scheme / struct_conn / struct_ref_seq_dif / struct_site / struct_site_gen Item : _atom_site.B_iso_or_equiv / _atom_site.Cartn_x ... _atom_site.B_iso_or_equiv / _atom_site.Cartn_x / _atom_site.Cartn_y / _atom_site.Cartn_z / _atom_site.auth_asym_id / _atom_site.auth_atom_id / _atom_site.auth_comp_id / _atom_site.auth_seq_id / _atom_site.label_atom_id / _atom_site.label_comp_id / _chem_comp.formula / _chem_comp.formula_weight / _chem_comp.id / _chem_comp.mon_nstd_flag / _chem_comp.name / _chem_comp.type / _entity.formula_weight / _entity.pdbx_description / _entity.type / _struct_ref_seq_dif.details Description : Carbohydrate remediation / Provider : repository / Type : RemediationRevision 2.1 Feb 28, 2024 Group : Data collection / Database references / Structure summaryCategory : chem_comp / chem_comp_atom ... chem_comp / chem_comp_atom / chem_comp_bond / database_2 Item : _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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