- PDB-4iaq: Crystal structure of the chimeric protein of 5-HT1B-BRIL in compl... -
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基本情報
登録情報
データベース: PDB / ID: 4iaq
タイトル
Crystal structure of the chimeric protein of 5-HT1B-BRIL in complex with dihydroergotamine (PSI Community Target)
要素
Chimera protein of human 5-hydroxytryptamine receptor 1B and E. Coli soluble cytochrome b562
キーワード
Signaling Protein / Electron Transport / dihydroergotamine / Novel protein engineering / GPCR Network / Membrane protein / PSI-Biology / Structural Genomics / GPCR / GPCR Dock
機能・相同性
機能・相同性情報
voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels / negative regulation of gamma-aminobutyric acid secretion / serotonergic synapse / G protein-coupled serotonin receptor complex / adenylate cyclase-inhibiting serotonin receptor signaling pathway / dopamine neurotransmitter receptor activity, coupled via Gs / regulation of behavior / negative regulation of synaptic transmission, GABAergic / response to mineralocorticoid / Serotonin receptors ...voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels / negative regulation of gamma-aminobutyric acid secretion / serotonergic synapse / G protein-coupled serotonin receptor complex / adenylate cyclase-inhibiting serotonin receptor signaling pathway / dopamine neurotransmitter receptor activity, coupled via Gs / regulation of behavior / negative regulation of synaptic transmission, GABAergic / response to mineralocorticoid / Serotonin receptors / negative regulation of serotonin secretion / drinking behavior / cellular response to temperature stimulus / bone remodeling / serotonin binding / negative regulation of synaptic transmission, glutamatergic / vasoconstriction / G protein-coupled serotonin receptor activity / : / G protein-coupled receptor internalization / neurotransmitter receptor activity / regulation of synaptic vesicle exocytosis / cellular response to alkaloid / regulation of dopamine secretion / calyx of Held / G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger / adenylate cyclase-activating adrenergic receptor signaling pathway / positive regulation of vascular associated smooth muscle cell proliferation / presynaptic modulation of chemical synaptic transmission / adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway / response to cocaine / electron transport chain / cellular response to xenobiotic stimulus / presynaptic membrane / G alpha (i) signalling events / chemical synaptic transmission / response to ethanol / periplasmic space / electron transfer activity / iron ion binding / dendrite / heme binding / endoplasmic reticulum / plasma membrane 類似検索 - 分子機能