登録情報 | データベース: PDB / ID: 4gvh |
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タイトル | Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) covalently bound to 5-fluoro-GlcNAc. |
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要素 | Beta-hexosaminidase |
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キーワード | HYDROLASE/SUBSTRATE / TIM-BARREL / HYDROLASE / 5-F-GlcNAc / HYDROLASE-SUBSTRATE complex |
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機能・相同性 | 機能・相同性情報
beta-N-acetylhexosaminidase activity / beta-N-acetylhexosaminidase / peptidoglycan turnover / N-acetyl-beta-D-galactosaminidase activity / peptidoglycan biosynthetic process / cell wall organization / regulation of cell shape / carbohydrate metabolic process / cell cycle / cell division ...beta-N-acetylhexosaminidase activity / beta-N-acetylhexosaminidase / peptidoglycan turnover / N-acetyl-beta-D-galactosaminidase activity / peptidoglycan biosynthetic process / cell wall organization / regulation of cell shape / carbohydrate metabolic process / cell cycle / cell division / response to antibiotic / cytoplasm類似検索 - 分子機能 Beta-hexosaminidase, bacterial / Glycoside hydrolase, family 3, active site / Glycosyl hydrolases family 3 active site. / Glycoside hydrolase, family 3, N-terminal domain / Glycoside hydrolase, family 3, N-terminal / Glycoside hydrolase, family 3, N-terminal domain superfamily / Glycosyl hydrolase family 3 N terminal domain / Glycoside hydrolase superfamily / TIM Barrel / Alpha-Beta Barrel / Alpha Beta類似検索 - ドメイン・相同性 5-fluoro-N-acetyl-alpha-D-glucosamine / Beta-hexosaminidase類似検索 - 構成要素 |
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生物種 | Salmonella enterica subsp. enterica serovar Typhimurium (サルモネラ菌) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.45 Å |
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データ登録者 | Bacik, J.P. / Mark, B.L. |
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引用 | ジャーナル: Chem.Biol. / 年: 2012 タイトル: Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion. 著者: Bacik, J.P. / Whitworth, G.E. / Stubbs, K.A. / Vocadlo, D.J. / Mark, B.L. |
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履歴 | 登録 | 2012年8月30日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2012年12月19日 | Provider: repository / タイプ: Initial release |
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改定 2.0 | 2020年7月29日 | Group: Atomic model / Database references ...Atomic model / Database references / Derived calculations / Structure summary カテゴリ: atom_site / chem_comp ...atom_site / chem_comp / entity / pdbx_entity_nonpoly / struct_conn / struct_ref_seq_dif / struct_site / struct_site_gen Item: _atom_site.auth_atom_id / _atom_site.label_atom_id ..._atom_site.auth_atom_id / _atom_site.label_atom_id / _chem_comp.name / _chem_comp.type / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.ptnr2_label_atom_id / _struct_ref_seq_dif.details 解説: Carbohydrate remediation / Provider: repository / タイプ: Remediation |
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