登録情報 | データベース: PDB / ID: 4gfx |
---|
タイトル | Crystal structure of the N-terminal domain of TXNIP |
---|
要素 | Thioredoxin-interacting protein |
---|
キーワード | PROTEIN BINDING / Arrestin-like fold |
---|
機能・相同性 | 機能・相同性情報
cellular response to tumor cell / cellular response to oxidised low-density lipoprotein particle stimulus / negative regulation of cell division / enzyme inhibitor activity / Regulation of FOXO transcriptional activity by acetylation / platelet-derived growth factor receptor signaling pathway / The NLRP3 inflammasome / Purinergic signaling in leishmaniasis infection / response to glucose / response to mechanical stimulus ...cellular response to tumor cell / cellular response to oxidised low-density lipoprotein particle stimulus / negative regulation of cell division / enzyme inhibitor activity / Regulation of FOXO transcriptional activity by acetylation / platelet-derived growth factor receptor signaling pathway / The NLRP3 inflammasome / Purinergic signaling in leishmaniasis infection / response to glucose / response to mechanical stimulus / keratinocyte differentiation / response to progesterone / response to hydrogen peroxide / Cytoprotection by HMOX1 / response to calcium ion / protein import into nucleus / protein transport / response to estradiol / regulation of cell population proliferation / response to xenobiotic stimulus / inflammatory response / positive regulation of apoptotic process / cell cycle / ubiquitin protein ligase binding / negative regulation of transcription by RNA polymerase II / cytoplasm / cytosol類似検索 - 分子機能 Immunoglobulin-like - #640 / Arrestin-like, N-terminal / Arrestin C-terminal-like domain / Arrestin (or S-antigen), N-terminal domain / Arrestin (or S-antigen), C-terminal domain / Arrestin (or S-antigen), C-terminal domain / Arrestin-like, C-terminal / Immunoglobulin E-set / Immunoglobulin-like / Sandwich / Mainly Beta類似検索 - ドメイン・相同性 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.6 Å |
---|
データ登録者 | Hwang, J. / Kim, M.H. |
---|
引用 | ジャーナル: Nat Commun / 年: 2014 タイトル: The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein. 著者: Hwang, J. / Suh, H.W. / Jeon, Y.H. / Hwang, E. / Nguyen, L.T. / Yeom, J. / Lee, S.G. / Lee, C. / Kim, K.J. / Kang, B.S. / Jeong, J.O. / Oh, T.K. / Choi, I. / Lee, J.O. / Kim, M.H. |
---|
履歴 | 登録 | 2012年8月4日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2014年2月5日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2024年4月3日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
---|
|
---|