Entry | Database: PDB / ID: 4gew |
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Title | Crystal structure of TDP2 from C. elegans |
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Components | 5'-tyrosyl-DNA phosphodiesterase |
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Keywords | HYDROLASE / 5'-phosphotyrosyl-DNA diesterase |
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Function / homology | Function and homology information
5'-tyrosyl-DNA phosphodiesterase activity / nuclease activity / Hydrolases; Acting on ester bonds; Phosphoric-diester hydrolases / PML body / double-strand break repair / single-stranded DNA binding / identical protein binding / metal ion binding / cytoplasmSimilarity search - Function UBA-like domain / Ubiquitin-associated (UBA) domain / Deoxyribonuclease I; Chain A / Endonuclease/exonuclease/phosphatase / Endonuclease/exonuclease/phosphatase / Endonuclease/Exonuclease/phosphatase family / Endonuclease/exonuclease/phosphatase superfamily / UBA-like superfamily / Helicase, Ruva Protein; domain 3 / 4-Layer Sandwich ...UBA-like domain / Ubiquitin-associated (UBA) domain / Deoxyribonuclease I; Chain A / Endonuclease/exonuclease/phosphatase / Endonuclease/exonuclease/phosphatase / Endonuclease/Exonuclease/phosphatase family / Endonuclease/exonuclease/phosphatase superfamily / UBA-like superfamily / Helicase, Ruva Protein; domain 3 / 4-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha BetaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_invertebrata.gif) Caenorhabditis elegans (invertebrata) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / FOURIER SYNTHESIS / Resolution: 2.35 Å |
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Authors | Shi, K. / Kurahashi, K. / Aihara, H. |
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Citation | Journal: Nat.Struct.Mol.Biol. / Year: 2012 Title: Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Authors: Shi, K. / Kurahashi, K. / Gao, R. / Tsutakawa, S.E. / Tainer, J.A. / Pommier, Y. / Aihara, H. |
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History | Deposition | Aug 2, 2012 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Oct 31, 2012 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jan 2, 2013 | Group: Database references |
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Revision 1.2 | Feb 28, 2024 | Group: Data collection / Database references / Derived calculations Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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