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Structure paper

TitleStructural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 19, Page 1372-1377, Year 2012
Publish dateMay 6, 2012 (structure data deposition date)
AuthorsShi, K. / Kurahashi, K. / Gao, R. / Tsutakawa, S.E. / Tainer, J.A. / Pommier, Y. / Aihara, H.
External linksNat. Struct. Mol. Biol. / PubMed:23104058
MethodsX-ray diffraction
Resolution1.662 - 2.5 Å
Structure data

PDB-4f1h:
Crystal structure of TDP2 from Danio rerio complexed with a single strand DNA
Method: X-RAY DIFFRACTION / Resolution: 1.662 Å

PDB-4f1i:
Crystal structure of SeMet TDP2 from Caenorhabditis elegans
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-4fpv:
Crystal structure of D. rerio TDP2 complexed with single strand DNA product
Method: X-RAY DIFFRACTION / Resolution: 1.73 Å

PDB-4fva:
Crystal structure of truncated Caenorhabditis elegans TDP2
Method: X-RAY DIFFRACTION / Resolution: 2.07 Å

PDB-4gew:
Crystal structure of TDP2 from C. elegans
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-MLI:
MALONATE ION

Source
  • danio rerio (zebrafish)
  • caenorhabditis elegans (invertebrata)
KeywordsHydrolase/DNA / 5'-tyrosyl DNA phosphodiesterase / Hydrolase-DNA complex / HYDROLASE / 5'-phosphotyrosyl-DNA diesterase

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