[English] 日本語
Yorodumi
- PDB-4dv4: Crystal structure of the Thermus thermophilus 30S ribosomal subun... -

+
Open data


ID or keywords:

Loading...

-
Basic information

Entry
Database: PDB / ID: 4dv4
TitleCrystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A914G
Components
  • (ribosomal protein ...) x 20
  • 16S rRNA
KeywordsRIBOSOME / decoding / Streptomycin / RNA structure / antibiotic resistance
Function / homology
Function and homology information


small ribosomal subunit / tRNA binding / rRNA binding / ribosome / structural constituent of ribosome / ribonucleoprotein complex / translation / mRNA binding / zinc ion binding / metal ion binding / cytoplasm
Similarity search - Function
Ribosomal protein S4/S9, N-terminal domain / Ribosomal Protein S4 Delta 41; Chain A, domain 1 / S16 Ribosomal Protein; Chain: A; / Ribosomal protein S16 / Ribosomal protein S18 / 30s Ribosomal Protein S18 / 30s ribosomal protein s13; domain 2 / Ribosomal protein S13/S18, C-terminal domain / Ribosomal protein S20 / 30s Ribosomal Protein S19; Chain A ...Ribosomal protein S4/S9, N-terminal domain / Ribosomal Protein S4 Delta 41; Chain A, domain 1 / S16 Ribosomal Protein; Chain: A; / Ribosomal protein S16 / Ribosomal protein S18 / 30s Ribosomal Protein S18 / 30s ribosomal protein s13; domain 2 / Ribosomal protein S13/S18, C-terminal domain / Ribosomal protein S20 / 30s Ribosomal Protein S19; Chain A / Ribosomal protein S19/S15 / Ribosomal protein S3, C-terminal domain / Ribosomal Protein S14/S29 / 30s Ribosomal Protein S14; Chain N / Ribosomal Protein S8; Chain: A, domain 1 - #30 / RNA-binding S4 domain / Ribosomal Protein S7 / Ribosomal protein S7/S5 / Ribosomal protein S6/Translation elongation factor EF1B / Ribosomal protein S3 C-terminal domain / Helix hairpin bin / Dna Ligase; domain 1 - #10 / Ribosomal protein S11/S14 / Ribosomal protein S10 / Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A / S15/NS1, RNA-binding / K homology (KH) domain / Double Stranded RNA Binding Domain - #20 / Helicase, Ruva Protein; domain 3 - #50 / Glucose-6-phosphate isomerase like protein; domain 1 / Ribosomal Protein S8; Chain: A, domain 1 / Ribosomal Protein S5; domain 2 - #10 / 30S ribosomal protein Thx / 30S ribosomal protein Thx / 30S ribosomal protein / GMP Synthetase; Chain A, domain 3 / Ribosomal Protein S5; domain 2 / Double Stranded RNA Binding Domain / Ribosomal protein S14, type Z / Helicase, Ruva Protein; domain 3 / Nucleic acid-binding proteins / Dna Ligase; domain 1 / Methane Monooxygenase Hydroxylase; Chain G, domain 1 / Ribosomal protein S14/S29 / Ribosomal protein S3, bacterial-type / Ribosomal protein S6, conserved site / Ribosomal protein S6 signature. / Ribosomal protein S19, bacterial-type / Ribosomal protein S7, bacterial/organellar-type / Ribosomal protein S11, bacterial-type / Ribosomal protein S13, bacterial-type / Ribosomal protein S20 / Ribosomal protein S20 superfamily / Ribosomal protein S20 / Ribosomal protein S9, bacterial/plastid / Ribosomal protein S4, bacterial-type / 30S ribosomal protein S17 / Ribosomal protein S5, bacterial-type / Ribosomal protein S6, plastid/chloroplast / Ribosomal protein S2, bacteria/mitochondria/plastid / Ribosomal protein S18, conserved site / Ribosomal protein S18 signature. / Ribosomal protein S16 / Ribosomal protein S16 / Ribosomal protein S16 domain superfamily / Ribosomal protein S15, bacterial-type / Ribosomal protein S6 / Ribosomal protein S6 / Ribosomal protein S6 superfamily / Ribosomal protein S12, bacterial-type / Translation elongation factor EF1B/ribosomal protein S6 / Ribosomal protein S18 / Ribosomal protein S18 / Ribosomal protein S18 superfamily / K Homology domain / K homology RNA-binding domain / Ribosomal protein S3, conserved site / Ribosomal protein S14, conserved site / Ribosomal protein S10, conserved site / : / K Homology domain, type 2 / Ribosomal protein S3, C-terminal / Ribosomal protein S3, C-terminal domain superfamily / Ribosomal protein S15/S19, conserved site / KH domain / Ribosomal protein S19/S15 / Ribosomal protein S19/S15, superfamily / Ribosomal protein S10 / Ribosomal protein S3, C-terminal domain / Few Secondary Structures / Irregular / Ribosomal protein S3 signature. / Ribosomal protein S10 signature. / Ribosomal protein S14 signature. / Ribosomal protein S7, conserved site / Ribosomal protein S17, conserved site / K homology domain superfamily, prokaryotic type / Ribosomal protein S19 / Ribosomal protein S2 signature 1. / Ribosomal protein S2, conserved site
Similarity search - Domain/homology
: / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / Small ribosomal subunit protein uS12 / Small ribosomal subunit protein uS14 / Small ribosomal subunit protein uS17 / Small ribosomal subunit protein uS8 / Small ribosomal subunit protein uS7 ...: / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / Small ribosomal subunit protein uS12 / Small ribosomal subunit protein uS14 / Small ribosomal subunit protein uS17 / Small ribosomal subunit protein uS8 / Small ribosomal subunit protein uS7 / Small ribosomal subunit protein uS2 / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS4 / Small ribosomal subunit protein uS9 / Small ribosomal subunit protein uS11 / Small ribosomal subunit protein uS13 / Small ribosomal subunit protein bS20 / Small ribosomal subunit protein uS12 / Small ribosomal subunit protein uS10 / Small ribosomal subunit protein uS19 / 30S ribosomal protein S17 / 30S ribosomal protein S14 type Z / 30S ribosomal protein S8 / Small ribosomal subunit protein uS5 / Small ribosomal subunit protein bTHX / Small ribosomal subunit protein uS15 / Small ribosomal subunit protein bS16 / Small ribosomal subunit protein bS6 / Small ribosomal subunit protein bS18
Similarity search - Component
Biological speciesThermus thermophilus (bacteria)
MethodX-RAY DIFFRACTION / SYNCHROTRON / FOURIER SYNTHESIS / Resolution: 3.651 Å
AuthorsDemirci, H. / Murphy IV, F. / Murphy, E. / Gregory, S.T. / Dahlberg, A.E. / Jogl, G.
CitationJournal: To be Published
Title: A structural basis for streptomycin resistance
Authors: Demirci, H. / Murphy IV, F. / Murphy, E. / Gregory, S.T. / Dahlberg, A.E. / Jogl, G.
History
DepositionFeb 22, 2012Deposition site: RCSB / Processing site: RCSB
Revision 1.0Feb 27, 2013Provider: repository / Type: Initial release

-
Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

Downloads & links

-
Assembly

Deposited unit
A: 16S rRNA
B: ribosomal protein S2
C: ribosomal protein S3
D: ribosomal protein S4
E: ribosomal protein S5
F: ribosomal protein S6
G: ribosomal protein S7
H: ribosomal protein S8
I: ribosomal protein S9
J: ribosomal protein S10
K: ribosomal protein S11
L: ribosomal protein S12
M: ribosomal protein S13
N: ribosomal protein S14
O: ribosomal protein S15
P: ribosomal protein S16
Q: ribosomal protein S17
R: ribosomal protein S18
S: ribosomal protein S19
T: ribosomal protein S20
U: ribosomal protein THX
hetero molecules


Theoretical massNumber of molelcules
Total (without water)791,058310
Polymers783,95221
Non-polymers7,106289
Water7,422412
1


  • Idetical with deposited unit
  • defined by author
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Unit cell
Length a, b, c (Å)402.638, 402.638, 174.747
Angle α, β, γ (deg.)90.000, 90.000, 90.000
Int Tables number92
Space group name H-MP41212

-
Components

-
RNA chain , 1 types, 1 molecules A

#1: RNA chain 16S rRNA /


Mass: 494186.781 Da / Num. of mol.: 1 / Mutation: A914G / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: GenBank: M26923.1

-
Ribosomal protein ... , 20 types, 20 molecules BCDEFGHIJKLMNOPQRSTU

#2: Protein ribosomal protein S2 /


Mass: 29317.703 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80371
#3: Protein ribosomal protein S3 /


Mass: 26751.076 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80372
#4: Protein ribosomal protein S4 /


Mass: 24373.447 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80373
#5: Protein ribosomal protein S5 /


Mass: 17583.416 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SHQ5
#6: Protein ribosomal protein S6 /


Mass: 11988.753 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SLP8
#7: Protein ribosomal protein S7 /


Mass: 18050.973 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P17291
#8: Protein ribosomal protein S8 /


Mass: 15868.570 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SHQ2, UniProt: P0DOY9*PLUS
#9: Protein ribosomal protein S9 /


Mass: 14410.614 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80374
#10: Protein ribosomal protein S10 /


Mass: 11954.968 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SHN7
#11: Protein ribosomal protein S11 /


Mass: 13737.868 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80376
#12: Protein ribosomal protein S12 /


Mass: 14966.846 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: F6DEQ7, UniProt: Q5SHN3*PLUS
#13: Protein ribosomal protein S13 /


Mass: 14338.861 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80377
#14: Protein ribosomal protein S14 /


Mass: 7158.725 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SHQ1, UniProt: P0DOY6*PLUS
#15: Protein ribosomal protein S15 /


Mass: 10578.407 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SJ76
#16: Protein ribosomal protein S16 /


Mass: 10409.983 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SJH3
#17: Protein ribosomal protein S17 /


Mass: 12324.670 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SHP7, UniProt: P0DOY7*PLUS
#18: Protein ribosomal protein S18 /


Mass: 10258.299 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SLQ0
#19: Protein ribosomal protein S19 / 40S ribosomal protein S19


Mass: 10605.464 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SHP2
#20: Protein ribosomal protein S20 /


Mass: 11736.143 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: P80380
#21: Protein/peptide ribosomal protein THX / Ribosome


Mass: 3350.030 Da / Num. of mol.: 1 / Source method: isolated from a natural source / Source: (natural) Thermus thermophilus (bacteria) / Strain: HB8 / References: UniProt: Q5SIH3

-
Non-polymers , 3 types, 701 molecules

#22: Chemical...
ChemComp-MG / MAGNESIUM ION


Mass: 24.305 Da / Num. of mol.: 287 / Source method: obtained synthetically / Formula: Mg
#23: Chemical ChemComp-ZN / ZINC ION


Mass: 65.409 Da / Num. of mol.: 2 / Source method: obtained synthetically / Formula: Zn
#24: Water ChemComp-HOH / water / Water


Mass: 18.015 Da / Num. of mol.: 412 / Source method: isolated from a natural source / Formula: H2O

-
Experimental details

-
Experiment

ExperimentMethod: X-RAY DIFFRACTION / Number of used crystals: 1

-
Sample preparation

CrystalDensity Matthews: 4.52 Å3/Da / Density % sol: 72.77 %
Crystal growTemperature: 277 K / Method: hanging drop / pH: 6.5 / Details: MPD, pH 6.5, HANGING DROP, temperature 277K

-
Data collection

DiffractionMean temperature: 100 K
Diffraction sourceSource: SYNCHROTRON / Site: APS / Beamline: 24-ID-C / Wavelength: 0.98 Å
DetectorType: ADSC QUANTUM 315 / Detector: CCD / Date: Nov 7, 2010
RadiationMonochromator: Kohzu HLD8-24 / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelengthWavelength: 0.98 Å / Relative weight: 1
ReflectionResolution: 3.65→35 Å / Num. all: 155290 / Num. obs: 155290 / % possible obs: 98.3 % / Observed criterion σ(F): -3 / Observed criterion σ(I): -3 / Redundancy: 3.2 % / Rmerge(I) obs: 0.08 / Χ2: 1.095 / Net I/σ(I): 13.5
Reflection shell
Resolution (Å)Redundancy (%)Rmerge(I) obsNum. unique allΧ2Diffraction-ID% possible all
3.65-3.783.20.686155211.027199.5
3.78-3.933.20.479155471.056199.5
3.93-4.113.20.345155621.077199.5
4.11-4.333.20.226155361.084199.3
4.33-4.63.20.152156031.128199.2
4.6-4.953.20.109155541.146199.1
4.95-5.453.20.082155961.013198.7
5.45-6.233.20.074155791.112198.4
6.23-7.843.20.065155581.209197.5
7.84-353.10.037152341.103192.7

-
Processing

Software
NameVersionClassificationNB
DENZOdata reduction
SCALEPACKdata scaling
PHENIXdev_978refinement
PDB_EXTRACT3.1data extraction
HKL-2000data collection
PHENIXdev_978phasing
RefinementMethod to determine structure: FOURIER SYNTHESIS / Resolution: 3.651→34.661 Å / Occupancy max: 1 / Occupancy min: 0.18 / FOM work R set: 0.8683 / SU ML: 0.28 / σ(F): 1.33 / Phase error: 20.06 / Stereochemistry target values: ML
RfactorNum. reflection% reflectionSelection details
Rfree0.2083 7744 4.99 %FROM PDB ENTRY 2VQE
Rwork0.1531 ---
obs0.1559 155190 98.2 %-
all-155190 --
Solvent computationShrinkage radii: 0.86 Å / VDW probe radii: 1.1 Å / Solvent model: FLAT BULK SOLVENT MODEL / Bsol: 108.135 Å2 / ksol: 0.253 e/Å3
Displacement parametersBiso max: 512.42 Å2 / Biso mean: 168.7769 Å2 / Biso min: 23.96 Å2
Baniso -1Baniso -2Baniso -3
1--6.6447 Å2-0 Å20 Å2
2---6.6447 Å20 Å2
3---6.993 Å2
Refinement stepCycle: LAST / Resolution: 3.651→34.661 Å
ProteinNucleic acidLigandSolventTotal
Num. atoms19088 32508 289 412 52297
Refine LS restraints
Refine-IDTypeDev idealNumber
X-RAY DIFFRACTIONf_bond_d0.01356351
X-RAY DIFFRACTIONf_angle_d1.6283602
X-RAY DIFFRACTIONf_chiral_restr0.09110413
X-RAY DIFFRACTIONf_plane_restr0.0094888
X-RAY DIFFRACTIONf_dihedral_angle_d19.90826123
LS refinement shell

Refine-ID: X-RAY DIFFRACTION / Total num. of bins used: 30

Resolution (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkNum. reflection all% reflection obs (%)
3.651-3.69250.34832770.29064708498596
3.6925-3.73580.32312560.273449305186100
3.7358-3.78130.30552920.260248905182100
3.7813-3.82920.31782100.24234940515099
3.8292-3.87950.26232640.229749645228100
3.8795-3.93250.29622680.231449145182100
3.9325-3.98870.27362470.209249655212100
3.9887-4.04810.25322800.20194874515499
4.0481-4.11130.25212850.19694916520199
4.1113-4.17850.23012410.17744966520799
4.1785-4.25050.25792530.17284932518599
4.2505-4.32760.23072600.16264896515699
4.3276-4.41070.20662750.15754934520999
4.4107-4.50050.20682920.14884906519899
4.5005-4.59820.20552550.14484946520199
4.5982-4.70490.20432380.14164938517699
4.7049-4.82230.19592270.12884992521999
4.8223-4.95230.19142800.12064912519299
4.9523-5.09760.17362560.1174945520199
5.0976-5.26160.16432380.10894933517199
5.2616-5.44890.17032530.11124958521199
5.4489-5.66620.18052650.1134931519699
5.6662-5.92290.16562540.10994949520398
5.9229-6.23340.17652460.11464941518798
6.2334-6.62150.18832540.12884926518098
6.6215-7.12860.18722540.12934937519198
7.1286-7.83850.18772520.124952520497
7.8385-8.95560.16032590.1224900515996
8.9556-11.21920.16862580.13374914517295
11.2192-34.66240.24922550.20874637489287
Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

IDL11 (°2)L12 (°2)L13 (°2)L22 (°2)L23 (°2)L33 (°2)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T11 (Å2)T12 (Å2)T13 (Å2)T22 (Å2)T23 (Å2)T33 (Å2)Origin x (Å)Origin y (Å)Origin z (Å)
10.46790.0607-0.17990.7321-0.04330.7272-0.0422-0.067-0.16040.23510.14470.15530.30320.1095-0.09410.94440.22360.14180.86230.00851.2228143.796783.4974-12.4037
23.2738-0.74520.56620.7278-0.03170.4253-0.1659-1.69220.54660.51810.2798-0.3263-0.1840.0154-0.1321.3611-0.17020.08362.6209-0.79021.7503223.1421129.26499.7966
34.57942.7112-0.94621.9399-0.65150.54140.0232-0.4971-1.07040.1344-0.0346-0.8330.26240.24830.02121.23960.19560.06321.2996-0.15581.5783167.142271.6603-25.8784
42.8592.23530.47115.8695-3.23073.2159-0.83390.43050.1598-1.04830.8783-1.0575-0.95090.72740.01541.9701-0.35550.6080.9360.1161.9136156.5959158.2079-34.432
56.03854.3746-4.02534.833-4.66294.5463-0.55950.33310.3309-1.9044-1.2453-1.44090.66670.50091.72592.12850.0120.59371.12470.20891.771153.0961150.8058-37.0977
66.43381.86012.97326.02133.68069.36250.4349-1.6531.2239-0.0286-0.24882.1538-0.2274-1.2061-0.14161.3478-0.57140.56071.105-0.15152.3589148.5263160.3437-19.9234
75.5644-1.93453.9173.11942.34868.63310.9505-0.04951.3052-0.7795-0.8409-0.6786-1.37251.6126-0.1191.4637-0.07550.77651.18390.14921.7489166.1889163.0068-17.7609
83.72742.072.34443.376-1.15874.24450.2426-0.66281.2170.34111.3079-0.7658-1.46521.135-1.4031.1922-0.07460.52381.3744-0.55941.7375174.5652156.3996-6.5609
90.1880.07380.2140.9003-0.28640.39920.0909-0.04890.90340.80660.5351-1.0666-0.72520.7713-0.55212.965-1.03930.72092.3574-1.01543.2481193.1362167.0842.3093
109.89645.51753.37383.75871.21893.2644-0.05190.10030.36520.33540.5354-0.5533-0.30020.8876-0.4231.2929-0.05460.50351.0147-0.57272.1997174.3299155.5796-10.7106
112.7815-2.17721.15442.81770.36912.83810.34790.1905-0.5512-1.49310.4885-0.9065-0.17110.766-0.65161.7394-0.18610.73260.7261-0.36622.0983157.4436151.8662-23.0595
127.1949-1.7602-2.52832.0824.46559.8582-0.25540.39120.8573-0.29620.0414-1.3981-1.23640.47650.05622.0632-0.13750.78120.78740.04632.2033158.1361167.9716-20.9763
130.0041-0.0104-0.04380.16860.51861.5879-0.5013-0.0259-0.16550.41830.7404-0.10150.70170.3444-0.14594.9441-0.36750.42171.4026-0.37363.558163.79174.6313-22.5827
14-0.00550.00320.00460.04570.25941.6761-0.16240.46730.0513-0.1873-0.05640.4158-0.72840.2207-0.11731.91640.2060.35773.218-1.54131.6458210.0473139.347527.5733
158.6827-2.93183.07895.8807-2.05957.5552-0.8845-0.82532.0287-0.1529-0.6924-0.29520.3727-1.92891.51981.69230.3606-0.06953.5427-0.30161.5227206.6954145.033135.2056
164.60480.18381.79292.52730.29310.8448-0.2265-0.48590.2580.59480.5359-0.2678-0.0952-0.1602-0.25932.3789-0.23110.40624.7311-0.9832.8754192.5431142.082144.8238
170.05360.0879-0.00310.2514-0.08010.05050.0861-0.29040.11040.54090.1164-0.1627-0.29370.2207-0.05122.4375-0.0063-0.08632.8183-1.22020.7737207.1543140.018746.6629
185.2775-0.34854.50630.0709-0.2983.8444-1.2-1.26991.21010.7681-0.67550.1401-0.5645-1.89091.64782.5110.513-0.33763.6553-1.05652.0141192.5449146.599630.7334
191.3986-1.7880.40816.71760.02691.30150.0814-0.3099-0.12780.55340.36331.11450.2377-0.2273-0.32951.1389-0.02640.33123.6196-0.52011.6184187.085130.380619.2082
208.16097.5946-3.84578.2505-5.06753.68630.2278-0.77831.87911.0974-0.2972-0.4944-0.80870.57280.14591.2583-0.3174-0.32482.7217-0.82142.4849196.4708144.773810.0069
215.09724.4259-4.32725.9458-5.16374.6052-0.735-1.9897-0.03170.53810.09560.49430.5164-0.62380.54811.54180.25170.06153.8832-0.26541.3396195.2807126.614123.8892
224.9920.2698-2.14640.18190.4993.21120.92030.4855-0.0157-0.5798-0.0589-0.4526-0.45980.0907-0.50140.73860.0780.27933.1975-0.90441.8842194.6684138.119516.8234
235.8039-5.7583-1.95625.86152.82446.4520.1268-0.5174-0.3110.47241.05620.62750.269-0.0869-1.122.33290.0935-0.2971.29260.02751.5977153.6308111.347737.7086
244.81590.58520.01354.5625-1.89760.80160.5063-2.06941.45540.1714-0.5073-0.4383-0.33590.92910.07431.69140.09740.0321.6489-0.45360.9631159.6377112.855725.8186
257.7359-1.33072.54891.9756-0.53932.0168-0.12660.8899-0.4156-0.615-0.5174-0.62711.24430.11830.53891.27340.37740.28561.2337-0.39571.378138.9533105.724520.0003
266.4373-0.31223.31826.4345-1.11066.0475-0.0067-0.74970.41260.6787-0.30670.26630.005-0.91470.33761.62470.16090.58351.1055-0.00550.8819132.4034107.258439.6899
272.1921-1.388-2.1022.58732.5392.86510.23721.0150.65570.3962-0.77960.2789-1.08480.43620.44571.33160.10020.51111.09880.22951.3556147.3457112.985617.468
284.5188-2.348-2.95637.57532.89278.21980.0087-1.36951.41290.85860.3569-0.60660.52460.8193-0.45090.9276-0.0122-0.17051.8453-0.52311.3221165.13125.42497.2555
295.93583.1497-4.56673.7523-0.80634.79730.2044-0.476-0.39420.4715-0.5042-0.7485-0.66440.71810.26791.02680.0310.02262.2349-0.65481.5826185.8258122.5471-2.9561
304.2316-4.6002-4.47997.20172.73416.8974-0.2152-0.71571.10420.74780.1137-0.13070.2576-0.31680.08071.1488-0.35830.31321.2991-0.69331.3446162.5949129.18764.9831
315.095-5.62146.28856.2094-6.94347.7714-0.8452-1.24741.35711.18620.7302-0.595-1.55760.10820.0951.3127-0.12970.19471.3789-0.47421.3708168.3974133.04725.8064
324.18466.17381.06219.14541.31872.0980.7797-0.13731.41750.46-0.63651.4448-0.9188-0.2876-0.09920.93940.16040.35561.4833-0.03251.4889145.7663129.00870.8195
334.59391.0872-6.39954.4926-1.5659.0165-0.88840.2561-0.8579-0.51370.0052-0.32870.1013-0.72540.74791.10550.37080.02150.9719-0.41611.394148.4369117.5721-2.5257
349.19273.57925.5799.57232.03915.9228-0.3957-1.5759-0.4331.25390.31330.52221.38560.53920.0260.7349-0.03770.20970.80.04580.6971152.3544118.19322.3793
353.8928-5.826-2.0779.13254.06673.35110.73961.45130.7061-0.346-0.7212-0.4558-0.53621.003-0.01111.13160.01060.17321.3094-0.16590.6378155.7671124.677-4.5756
364.7966-3.50584.97543.4167-3.76615.1771-0.2635-1.45010.5941.3514-0.47131.5287-1.4494-2.01360.49491.0280.30410.37071.2771-0.01751.1912136.0148134.2321-8.7958
378.4635-1.229-5.77453.74011.39396.4189-0.1363-0.16530.29390.6692-0.21710.6492-0.71070.74340.28891.91-0.0126-0.04711.5709-0.1040.674168.1191117.0808-84.7339
381.63451.97792.55172.83634.64589.45580.4551.93160.8632-1.54660.222-0.8562-1.59831.7617-0.65962.250.51061.0642.59220.23721.9125187.2982116.8494-96.4528
395.52021.1627-6.76310.8537-1.55248.3006-0.93381.0669-0.2322-1.2710.4902-0.06640.26560.26340.29232.21030.2387-0.26212.0707-0.51010.5428174.336112.5356-98.4609
404.4821-0.6068-1.78097.9789-2.28153.46290.23890.14560.1748-0.27120.13160.1384-1.3344-0.2799-0.30762.4664-0.2285-0.06052.4120.34591.2365166.0317118.9797-91.4573
419.0688-4.14937.3763.7093-2.16758.61940.03060.84060.323-0.722-0.2926-0.1612-1.5661-0.18210.21662.5128-0.12750.80982.58350.0931.0112184.5456126.5323-88.8698
425.4029-4.85692.98164.7779-0.97119.0555-0.3851.3441-0.3804-1.10580.1935-2.32730.18421.92170.18961.1014-0.13410.09841.9475-0.07221.5156190.4506117.9308-83.1256
430.4658-0.7081.25382.6452-1.54733.7628-0.36830.2590.111-0.51140.66910.7894-0.6264-0.8666-0.30391.66620.3840.24521.58230.33380.9785172.1474119.3507-88.5309
443.1636-2.0303-0.74782.8199-2.86138.57320.309-0.1283-1.94820.74950.04590.59681.1011-0.1845-0.31492.21310.21240.52360.52960.02151.9269169.0448106.3997-85.3032
452.98393.4186-0.54515.3777-3.66136.40290.69380.8539-1.0515-0.623-0.7682-0.61420.54030.9064-0.02341.4483-0.05880.30092.2349-0.48291.0172177.8431112.7123-85.8996
464.55515.09114.72876.1425.92645.8058-0.88210.20011.5671-0.6749-0.0291.1168-0.3101-0.20110.9021.4024-0.0365-0.21451.70021.20372.2643165.8753131.478-73.491
474.05385.70541.42398.03821.96780.6611-0.68953.01833.68590.0583-0.19332.0486-0.52330.43190.74331.2606-0.3130.20812.0525-0.00883.4101217.949143.3084-22.5168
488.02432.197-0.01122.0265-1.75266.7517-0.2544-0.26431.32770.41780.15810.0526-0.2555-0.6561-0.01410.9813-0.08050.65151.7114-0.29822.4514239.842146.0514-22.1063
495.13912.6526.58577.18342.14719.5748-1.74873.08350.65270.31730.6902-0.6346-0.74121.67430.99321.6198-0.12790.33991.92840.18922.2883248.3481145.5091-29.834
502.74323.21051.46786.05641.49322.06630.3601-0.67980.52860.373-0.39010.67480.9032-1.12190.10081.5826-0.4322-0.20353.9503-0.16491.0856226.2467131.3325-38.3479
519.84168.1780.84098.39761.43864.6418-0.07880.42020.12650.05140.98390.86252.15950.1297-0.78592.27290.329-0.05992.78720.26691.4312219.868124.4762-38.0245
523.12292.2463.60921.81022.11835.5664-0.05140.52070.78680.4139-0.2438-0.05090.2708-0.59770.30281.1089-0.43390.31151.5927-0.27632.9441236.2705135.9484-30.2632
534.8049-2.2279-0.22262.153-0.71796.2255-0.19890.4474-0.8396-0.3930.2295-0.48340.31441.73760.17320.7947-0.18540.7431.7937-0.21822.1866251.5171135.7008-30.3005
544.99094.36611.44324.5209-0.98547.994-0.66881.8735-2.2799-0.8209-0.296-2.35691.09011.34990.89461.37780.14630.30841.83530.07482.0469238.5117129.4711-40.1487
559.58671.9899.6018.33241.0039.73720.6937-0.55151.7915-0.55830.6889-0.7536-0.71660.1878-1.21992.37890.01821.50352.161-0.3012.7386220.1606126.0246-44.4671
567.86062.2054-0.43055.7971-0.67182.3004-0.19010.0991-0.2886-0.40160.02660.04610.83130.53890.25251.30150.16571.04191.0408-0.32251.1203140.7536123.2702-30.3246
575.17043.97553.48864.63385.3639.51060.2378-0.31090.5446-0.27990.04211.4021-0.9124-1.3121-0.22370.88580.43310.31660.85220.37241.2904131.6766128.6396-28.5683
587.87310.6374.89549.19853.84184.623-0.69630.51331.4711-0.04160.31430.683-1.9462-0.7920.38161.0160.22760.22520.70060.17911.4196132.3355132.9524-34.4452
594.8482.98210.64593.3850.56131.7570.435-0.44110.68481.21150.1010.06630.09750.0652-0.47750.92720.32480.11450.87710.04980.8614141.5499126.4837-19.5875
605.16043.32550.98325.05680.64394.76530.0885-1.3089-0.40441.3894-0.08710.45540.12360.0544-0.0451.26570.27990.55811.00320.16120.9012129116.8117-13.8231
615.89134.92351.23944.17371.73917.2490.2726-1.03340.28170.6796-0.9610.09920.7191-0.00670.69741.01010.24770.17130.81150.13740.6875126.9765118.5558-17.0748
621.1956-1.01680.06515.31471.60321.94070.349-0.36420.9896-0.22960.2016-0.2693-0.53370.5361-0.4621.6118-0.5667-0.23591.8473-1.0243.4536241.8092166.284-3.5712
637.66223.7199-6.27392.2338-3.16385.16810.77140.34182.69430.0755-0.079-0.085-1.10670.2646-0.69151.4669-0.31070.93612.8705-0.95063.6084250.4003155.8662-7.8058
641.8442-0.32111.75760.21470.33414.7778-0.5940.20240.9548-0.1298-0.25190.0385-1.01670.14610.74011.9379-0.319-0.61251.7192-0.59973.8551242.6606164.5265-11.1249
656.92322.2661.22681.6519-0.35052.77010.42150.23710.1059-0.12090.57060.498-0.09930.5274-0.66630.9373-0.28060.23051.4786-0.93273.5898236.7428163.9201-7.8485
662.76211.0834-1.69260.4886-0.84193.55-0.63170.42360.4075-0.94650.1868-0.36880.4642-0.42150.39251.9021-0.47540.70992.0905-0.81154.434229.6272166.9468-14.5935
673.1627-3.73620.07067.1748-2.86913.90310.4539-0.192-0.1106-0.1432-0.4361.16750.0664-0.3038-0.02741.1362-0.48440.19612.5708-1.1651.9526223.8193131.8713-3.6778
680.197-0.01940.24460.1861-0.10780.34131.05450.4419-0.24910.0001-0.70470.67690.3202-0.2151-0.1072.66220.45680.16622.7651-1.70532.9843227.4607157.380328.8221
699.3124-2.2614-3.18066.7753-5.03376.7169-0.015-0.01380.85091.8420.5563-0.07-1.4739-0.8208-0.38561.82970.4535-0.26973.5928-1.61122.7791218.3103165.218227.4131
703.68790.9981-1.75053.0394-3.21733.54750.1603-0.45591.19441.38170.4296-1.4604-2.95290.8419-0.54212.6762-0.3548-0.21892.7208-1.72743.5305228.5488166.356523.6398
712.058-2.0118-0.9373.49572.76246.28840.1937-0.34590.72870.57210.07990.0603-0.07781.5977-0.46841.9272-0.34941.00663.5152-0.94762.1708224.4398139.992116.8071
721.1516-0.03660.07931.4066-1.65852.1858-0.75890.0629-0.098-0.88870.5012-0.7126-0.6738-0.52160.282.1963-0.32710.19443.2716-1.00271.9193219.0537136.530614.1054
730.2595-0.1404-0.00210.3014-0.07240.0249-0.2732-0.07030.0791.18450.34490.2036-0.9332-0.0482-0.01372.94460.1970.25872.7063-1.78193.0077227.2707171.080436.5778
740.01010.1-0.09770.9152-0.9010.88630.6558-2.30161.66751.2018-0.07940.4258-0.58910.4145-0.46561.5491-0.25630.09714.3964-1.81773.563217.0381159.985535.5205
750.09580.0647-0.08040.0554-0.09490.1872-0.74520.3013-0.3628-0.3281-0.19360.91040.1783-0.60430.78932.70890.3931-0.08183.584-1.84532.5589229.2788156.30733.9229
766.9752-1.50065.98616.6708-3.11365.9267-0.61240.64410.0785-0.22580.0269-0.3901-0.0763-0.71280.5361.1720.0460.40830.912-0.10281.7804213.3262118.7404-69.6454
778.47621.6358-3.11737.0762.09932.42240.06730.4590.4456-1.00820.625-1.8506-0.60062.0882-0.66450.9797-0.06450.50441.4088-0.04871.7137217.7317114.8645-66.4202
786.67081.12113.30399.3313-1.94218.92950.4780.38650.62161.1031-0.7471-1.32330.70940.62950.32380.8691-0.15880.21841.5509-0.39651.4217220.4299120.6477-61.799
795.6091-5.889-3.42518.96446.45025.0172-1.45291.3888-0.9351-2.3601-0.7175-0.76010.4452-0.4571.88461.0784-0.4170.21941.97540.23821.3512211.589124.9827-71.6836
804.70086.0221-3.89119.5811-4.34513.44120.7918-2.31040.69391.99260.1115-0.5876-1.79460.6794-0.79891.29290.2215-0.31821.9449-0.4211.0979211.4358126.4922-59.3473
816.15853.10415.13651.94763.09224.9423-0.1407-0.4691.38470.4549-1.712-1.3763-1.77941.87981.73391.3259-0.52190.04591.37570.52932.3119211.8708130.3499-69.5682
822.02711.15330.53125.1721-4.38646.02780.9310.6930.2085-0.3566-0.4329-0.7312-0.49140.8007-0.43771.5876-0.32290.74991.9083-0.54831.6583193.9026110.5739-57.909
835.16862.59523.73153.7344-0.24734.5492-0.02221.0343-0.2688-0.3078-0.0153-0.71480.18690.7290.05010.60520.19140.08521.1581-0.26621.6665145.038899.3176-27.5011
843.9648-6.1544.03379.7407-6.46194.38740.67661.2809-1.0784-0.9366-1.1101-0.62491.40961.84960.47041.05040.00910.08751.41430.09761.0567153.785290.0644-15.4226
857.5224-0.8136-3.27894.6592-4.11376.29610.3770.7489-0.2512-0.80220.66280.72371.1948-0.8185-1.01211.61810.5699-0.61021.56950.31971.6605161.164577.7041.3697
866.47676.28651.83489.26351.40666.3979-0.50561.39-0.76540.36470.8305-0.93351.3851.4789-0.30491.31150.38560.10961.40090.00861.4406176.454576.73344.1593
873.80085.2662-1.9677.9706-0.38289.68830.1379-0.1360.617-0.0044-1.0811-0.99380.2381.030.87471.3620.2617-0.191.33080.23451.3776173.828278.42028.3815
886.2902-1.3197-1.51657.0393-1.76232.31580.1743-1.48760.53910.1713-0.318-1.11930.82650.74130.06581.47560.4684-0.30021.97920.01961.382170.486181.250624.2805
898.5049-4.78594.02085.4665-4.53283.7584-0.7149-0.7558-0.0971-0.58930.11560.40781.3672-0.66610.44561.4963-0.1010.21991.9895-0.52652.3706274.5324116.2178-8.0306
903.34382.2838-0.41095.8585-1.94655.97410.4246-0.6771.7690.6903-0.92490.0527-0.47460.69790.47550.86610.1222-0.30272.3583-0.57032.1613275.3163120.86-0.1664
917.33940.9357-6.59155.4501-3.72287.5095-0.0441-0.9615-0.18090.1532-0.48760.3650.3541-0.27550.53351.5035-0.0087-0.38782.216-0.3351.4141257.444699.981310.9996
929.3161.1325-2.15526.471-0.54955.1484-0.835-0.4797-0.4229-0.0248-0.33090.8194-0.1144-0.16821.09020.9939-0.2706-0.15142.5382-0.03732.3619240.9939103.87592.0401
937.2466-1.5844-5.56787.1191-2.37016.17660.091-1.87790.63671.5207-0.21510.25530.28770.170.16862.26210.50580.30333.8276-1.08721.7129220.4743117.235334.0953
940.8481-1.24370.81152.8863-2.66812.8713-0.269-1.06110.44230.92170.27250.6544-0.3539-0.225-0.04771.49780.2272-0.08774.0972-0.50242.1733232.6846119.071235.3911
951.32192.07862.47144.25015.41967.018-0.03411.6429-0.5004-1.8658-1.4768-0.00650.6946-0.21811.41042.28080.36490.41332.4764-0.56011.8025219.1121123.4226.2808
961.1836-1.6989-2.02242.61142.534.7529-0.50410.56120.0137-0.2885-0.1813-1.0140.24870.83110.62821.5858-0.26170.16853.4452-0.41332.1063222.4618131.383524.1193
974.42453.7194-0.02945.6184-2.74646.2665-0.7169-0.24271.2932-0.0985-0.25470.9819-0.5734-0.79390.87691.12240.1205-0.4222.6296-0.85971.8233214.0273137.297518.5691
988.6055-4.18223.41516.3483-0.04314.50041.09061.67890.7366-2.03030.08210.0872-0.5479-0.3505-1.10221.3933-0.0290.11681.51870.44320.9466144.1669106.5699-68.8252
991.9471-3.35491.25516.8417-0.09214.85890.3736-2.7138-0.65610.5150.85450.07880.35741.022-1.1040.97870.1282-0.09671.6321-0.00650.7499143.9823101.9679-56.3298
1003.5067-0.9705-3.2873.08222.80964.363-0.37451.156-1.6082-0.00070.27512.10291.8774-1.83630.10271.5144-0.1613-0.26921.58060.02122.1962131.149598.2865-63.5793
1015.76850.71814.92475.89522.60937.4894-0.19260.1021-0.1692-0.18420.199-0.24750.25450.8244-0.06251.49350.35760.8150.96960.3611.4797112.441972.66639.9573
1027.41341.88615.84181.00320.87667.15440.14330.4053-0.17060.73160.2835-0.19660.26961.0822-0.49511.1740.20880.64121.2347-0.31211.5429118.706278.769815.2999
1035.1134-3.0089-2.51489.4401-2.96113.8291-0.28260.4-0.24260.49250.029-0.44930.7312-0.18670.23871.9953-0.01770.38221.1537-0.02531.3165117.919773.46024.7239
1044.65951.8892.51584.79674.36114.33390.7195-0.24772.13380.1890.99470.3176-1.95280.3422-1.45791.4693-0.39160.56771.17-0.06672.2889111.133284.60418.722
1052.45212.9371-1.97858.52853.11367.5999-0.54350.33930.901-0.6922-0.30810.7186-1.2215-0.25620.73681.42740.38960.40611.47960.96863.0398100.836779.95745.1457
1065.4438-3.88836.78918.0929-2.76851.99970.6844-0.1358-0.693-0.58420.3881.12231.3767-0.0934-1.09511.90550.32540.59950.58840.39561.9106104.160270.84147.6096
1078.15753.6589-0.96875.0974-3.87553.5420.8588-0.9986-0.60641.2819-0.524-0.02250.4694-0.5161-0.36812.3988-0.34150.70631.15140.51312.2014104.369974.632418.4544
1084.91225.79871.36499.478-0.68873.044-0.6066-0.5433-0.51950.7116-1.25242.13680.9855-2.56691.68811.7112-0.15930.97931.522-0.28652.452893.785579.611215.7879
1098.36960.3138-5.33919.82541.0113.5543-0.676-0.23240.46390.20320.71360.18010.2821-0.3718-0.0480.5860.11340.11040.97840.47171.6455119.569685.183-34.4009
1102.94431.84931.04636.4284-3.40143.50020.1331.7238-0.1325-0.64930.3717-0.4846-0.1945-0.5758-0.49591.42250.37480.24992.0367-0.55711.6255122.653672.8298-45.7443
1115.13092.32285.77532.53012.73226.5066-0.13420.2047-0.0523-0.09860.2840.2798-0.68160.6184-0.17990.7214-0.20650.19270.90530.26241.6725126.795588.1514-33.6153
1128.2912-0.48095.13232.0177-0.13633.2124-0.2472-0.8912-0.92260.7421-1.149-0.60750.64580.44671.20270.94470.01010.37081.14940.26130.8729137.932798.5233-21.4787
1130.04550.42970.46075.20275.30865.4232-1.0476-1.1170.475-0.23510.9340.94210.51580.5120.13560.82190.1034-0.02831.1050.18731.7595127.910985.8375-33.2223
1144.27384.2667-5.10958.8286-4.60616.1632-0.12182.42580.6009-1.83070.80332.6490.721-2.0985-0.60261.4495-0.2265-0.33481.69860.45561.8235116.237280.0956-46.1787
1155.19395.05942.02614.93572.06882.1832-0.0515-0.61230.66380.35-0.18350.3505-2.4727-0.86810.23710.76550.0097-0.04610.72130.21171.6368116.473884.8178-34.7735
1165.87-2.76171.92676.68322.82593.21270.0596-0.60740.38790.7084-0.9192-0.1172-0.29980.63860.82350.8923-0.35630.09381.37750.44191.1828117.946280.0702-36.389
1172.1108-3.90510.78167.86-3.45799.39790.45350.0340.6701-0.008-0.0382-0.067-0.13980.489-0.37721.4251-0.1380.29981.37040.03991.0227137.949585.8008-44.7991
1181.4919-2.926-0.98247.16710.77051.5818-0.2848-0.17841.5708-0.00620.0366-0.0422-0.96480.28920.2762.172-0.47460.63190.8144-0.18772.7776180.3871140.5082-64.3524
1197.20316.2623.91138.94085.31163.16390.05050.31720.7266-0.4966-0.90450.6963-1.1747-0.62660.80131.27840.063-0.07712.1640.62811.7032173.1217132.3238-75.65
1204.17384.61011.11586.09031.19567.22680.87621.17041.6432-0.92670.4458-0.5137-2.14160.6164-1.3371.41740.47040.8871.29510.65921.8909181.4794132.9864-74.7031
1216.7625-5.2199-0.95094.32131.69433.29510.5499-0.1241.2809-0.21470.4284-3.9955-0.45373.0207-0.92050.75330.07850.05752.1057-0.59091.8084186.6763128.4432-66.1456
1228.78421.9373-0.87332.60080.53537.07410.4652-0.19281.1702-0.4030.1031-0.5065-0.20641.1762-0.4941.61960.12650.71781.80620.12380.9544178.2956133.9744-60.9068
1232.9302-2.6978-4.79027.33152.16159.35021.4161-0.50250.39330.083-0.09880.8497-0.0669-0.9837-1.21861.3016-0.09920.2071.10550.26421.0479174.9408124.4369-69.0533
1247.1332.03174.71784.74242.9247.58290.45140.1256-0.0222-0.47240.0083-1.46350.59450.5869-0.45091.65140.21790.30571.23830.24921.5879192.3047125.5005-71.7756
1255.71511.5846-4.31447.1274-6.40747.6218-0.61861.8794-0.6177-1.45740.15471.34371.6539-1.38840.42922.23610.805-0.86673.2243-1.17172.3056252.8242112.889428.2785
1261.42571.7826-1.45793.24170.04196.5251-1.021-1.84540.89541.8308-0.6882-0.5171-0.8757-0.41651.482.57170.7484-0.75563.7556-0.63811.6589252.1958100.144342.5608
1273.078-2.4878-3.04413.78533.7894.0057-0.1090.13060.52740.15990.7495-0.7461-0.65231.4971-0.5972.14980.46370.04013.79150.05192.3711252.92488.853539.4864
1281.56282.4955-2.39645.0309-3.38973.8463-0.9196-0.563-0.16850.4684-0.27112.1151-1.0413-1.13461.02911.08370.4135-0.28873.76570.22562.3424245.0707101.275232.0973
1299.37723.86770.54471.83740.31010.0630.2157-0.45580.85870.0641-0.07260.7369-0.2046-0.6733-0.06491.68820.1571-0.11993.75870.13373.0074252.058396.529332.8935
1300.04480.5309-0.10296.4131-2.12573.3065-0.1559-0.7466-1.35710.86230.2262-0.2571-0.11590.4344-0.04561.72960.3931-0.22342.84910.20232.2712248.776893.548426.9649
1310.0920.0772-0.08910.0644-0.07540.08620.53331.25930.7567-1.5255-0.21740.4188-0.5396-0.0835-0.22522.6577-0.4211-0.5663.50771.44261.993253.5796103.136625.8899
1328.4899-6.71765.71516.0539-4.94744.0918-0.9482-0.4691-0.00771.5414-0.0958-1.6017-0.78491.35080.93382.18180.0173-0.18632.72220.52682.206241.920496.25817.1828
1333.26050.14223.14950.69510.83383.9488-0.3753-0.476-0.0960.20660.3960.37120.4673-0.0234-0.10321.4539-0.25750.29260.51660.1361.6141113.556441.5216-14.7732
1347.32952.4288-0.16533.10172.99974.08820.3602-1.21290.0281-0.4069-0.4460.89111.0727-0.29820.2941.8095-0.13170.01660.57330.64791.9254100.623345.0232-25.9153
1355.40640.38483.38676.17813.98794.4038-0.3290.69190.3379-0.0223-0.53950.7630.4411-0.31470.58891.5994-0.52640.31781.31660.53491.836199.600550.3784-35.1173
1369.4715-0.56858.14950.1171-0.37067.17890.40951.1774-0.7598-0.3021-0.39390.31490.40331.00930.0210.9561-0.11460.15482.602-0.25892.4845251.8433124.64192.7463
1377.54282.19312.79313.88911.30965.6840.3025-0.3919-0.00710.157-0.0586-0.3657-1.1240.932-0.1562.0515-0.1943-0.68232.2083-1.17521.9012252.0274131.42068.1749
Refinement TLS group
IDRefine-IDRefine TLS-IDSelection detailsAuth asym-IDAuth seq-ID
1X-RAY DIFFRACTION1chain 'A' and (resseq 5:920)A5 - 920
2X-RAY DIFFRACTION2chain 'A' and (resseq 921:1400)A921 - 1400
3X-RAY DIFFRACTION3chain 'A' and (resseq 1401:1544)A0
4X-RAY DIFFRACTION4chain 'B' and (resseq 7:25)B7 - 25
5X-RAY DIFFRACTION5chain 'B' and (resseq 26:43)B26 - 43
6X-RAY DIFFRACTION6chain 'B' and (resseq 44:63)B44 - 63
7X-RAY DIFFRACTION7chain 'B' and (resseq 64:87)B64 - 87
8X-RAY DIFFRACTION8chain 'B' and (resseq 88:121)B88 - 121
9X-RAY DIFFRACTION9chain 'B' and (resseq 122:131)B122 - 131
10X-RAY DIFFRACTION10chain 'B' and (resseq 132:180)B132 - 180
11X-RAY DIFFRACTION11chain 'B' and (resseq 181:207)B181 - 207
12X-RAY DIFFRACTION12chain 'B' and (resseq 208:226)B208 - 226
13X-RAY DIFFRACTION13chain 'B' and (resseq 227:240)B227 - 240
14X-RAY DIFFRACTION14chain 'C' and (resseq 2:50)C2 - 50
15X-RAY DIFFRACTION15chain 'C' and (resseq 51:70)C51 - 70
16X-RAY DIFFRACTION16chain 'C' and (resseq 71:82)C71 - 82
17X-RAY DIFFRACTION17chain 'C' and (resseq 83:101)C83 - 101
18X-RAY DIFFRACTION18chain 'C' and (resseq 102:112)C102 - 112
19X-RAY DIFFRACTION19chain 'C' and (resseq 113:169)C113 - 169
20X-RAY DIFFRACTION20chain 'C' and (resseq 170:182)C170 - 182
21X-RAY DIFFRACTION21chain 'C' and (resseq 183:193)C183 - 193
22X-RAY DIFFRACTION22chain 'C' and (resseq 194:207)C194 - 207
23X-RAY DIFFRACTION23chain 'D' and (resseq 2:34)D2 - 34
24X-RAY DIFFRACTION24chain 'D' and (resseq 35:68)D35 - 68
25X-RAY DIFFRACTION25chain 'D' and (resseq 69:99)D69 - 99
26X-RAY DIFFRACTION26chain 'D' and (resseq 100:194)D100 - 194
27X-RAY DIFFRACTION27chain 'D' and (resseq 195:209)D195 - 209
28X-RAY DIFFRACTION28chain 'E' and (resseq 5:16)E5 - 16
29X-RAY DIFFRACTION29chain 'E' and (resseq 17:27)E17 - 27
30X-RAY DIFFRACTION30chain 'E' and (resseq 28:50)E28 - 50
31X-RAY DIFFRACTION31chain 'E' and (resseq 51:63)E51 - 63
32X-RAY DIFFRACTION32chain 'E' and (resseq 64:79)E64 - 79
33X-RAY DIFFRACTION33chain 'E' and (resseq 80:103)E80 - 103
34X-RAY DIFFRACTION34chain 'E' and (resseq 104:127)E104 - 127
35X-RAY DIFFRACTION35chain 'E' and (resseq 128:141)E128 - 141
36X-RAY DIFFRACTION36chain 'E' and (resseq 142:154)E142 - 154
37X-RAY DIFFRACTION37chain 'F' and (resseq 1:10)F1 - 10
38X-RAY DIFFRACTION38chain 'F' and (resseq 11:15)F11 - 15
39X-RAY DIFFRACTION39chain 'F' and (resseq 16:32)F16 - 32
40X-RAY DIFFRACTION40chain 'F' and (resseq 33:42)F33 - 42
41X-RAY DIFFRACTION41chain 'F' and (resseq 43:47)F43 - 47
42X-RAY DIFFRACTION42chain 'F' and (resseq 48:56)F48 - 56
43X-RAY DIFFRACTION43chain 'F' and (resseq 57:68)F57 - 68
44X-RAY DIFFRACTION44chain 'F' and (resseq 69:81)F69 - 81
45X-RAY DIFFRACTION45chain 'F' and (resseq 82:92)F82 - 92
46X-RAY DIFFRACTION46chain 'F' and (resseq 93:101)F93 - 101
47X-RAY DIFFRACTION47chain 'G' and (resseq 2:11)G2 - 11
48X-RAY DIFFRACTION48chain 'G' and (resseq 12:35)G12 - 35
49X-RAY DIFFRACTION49chain 'G' and (resseq 36:69)G36 - 69
50X-RAY DIFFRACTION50chain 'G' and (resseq 70:78)G70 - 78
51X-RAY DIFFRACTION51chain 'G' and (resseq 79:92)G79 - 92
52X-RAY DIFFRACTION52chain 'G' and (resseq 93:110)G93 - 110
53X-RAY DIFFRACTION53chain 'G' and (resseq 111:129)G111 - 129
54X-RAY DIFFRACTION54chain 'G' and (resseq 130:144)G130 - 144
55X-RAY DIFFRACTION55chain 'G' and (resseq 145:156)G145 - 156
56X-RAY DIFFRACTION56chain 'H' and (resseq 1:19)H1 - 19
57X-RAY DIFFRACTION57chain 'H' and (resseq 20:42)H20 - 42
58X-RAY DIFFRACTION58chain 'H' and (resseq 43:62)H43 - 62
59X-RAY DIFFRACTION59chain 'H' and (resseq 63:95)H63 - 95
60X-RAY DIFFRACTION60chain 'H' and (resseq 96:116)H96 - 116
61X-RAY DIFFRACTION61chain 'H' and (resseq 117:138)H117 - 138
62X-RAY DIFFRACTION62chain 'I' and (resseq 2:32)I2 - 32
63X-RAY DIFFRACTION63chain 'I' and (resseq 33:40)I33 - 40
64X-RAY DIFFRACTION64chain 'I' and (resseq 41:69)I41 - 69
65X-RAY DIFFRACTION65chain 'I' and (resseq 70:88)I70 - 88
66X-RAY DIFFRACTION66chain 'I' and (resseq 89:106)I89 - 106
67X-RAY DIFFRACTION67chain 'I' and (resseq 107:128)I107 - 128
68X-RAY DIFFRACTION68chain 'J' and (resseq 3:12)J3 - 12
69X-RAY DIFFRACTION69chain 'J' and (resseq 13:29)J13 - 29
70X-RAY DIFFRACTION70chain 'J' and (resseq 30:42)J30 - 42
71X-RAY DIFFRACTION71chain 'J' and (resseq 43:49)J43 - 49
72X-RAY DIFFRACTION72chain 'J' and (resseq 50:71)J50 - 71
73X-RAY DIFFRACTION73chain 'J' and (resseq 72:84)J72 - 84
74X-RAY DIFFRACTION74chain 'J' and (resseq 85:94)J85 - 94
75X-RAY DIFFRACTION75chain 'J' and (resseq 95:100)J95 - 100
76X-RAY DIFFRACTION76chain 'K' and (resseq 11:34)K11 - 34
77X-RAY DIFFRACTION77chain 'K' and (resseq 35:52)K35 - 52
78X-RAY DIFFRACTION78chain 'K' and (resseq 53:75)K53 - 75
79X-RAY DIFFRACTION79chain 'K' and (resseq 76:86)K76 - 86
80X-RAY DIFFRACTION80chain 'K' and (resseq 87:99)K87 - 99
81X-RAY DIFFRACTION81chain 'K' and (resseq 100:110)K100 - 110
82X-RAY DIFFRACTION82chain 'K' and (resseq 111:126)K111 - 126
83X-RAY DIFFRACTION83chain 'L' and (resseq 5:12)L5 - 12
84X-RAY DIFFRACTION84chain 'L' and (resseq 13:22)L13 - 22
85X-RAY DIFFRACTION85chain 'L' and (resseq 23:32)L23 - 32
86X-RAY DIFFRACTION86chain 'L' and (resseq 33:69)L33 - 69
87X-RAY DIFFRACTION87chain 'L' and (resseq 70:101)L70 - 101
88X-RAY DIFFRACTION88chain 'L' and (resseq 102:128)L102 - 128
89X-RAY DIFFRACTION89chain 'M' and (resseq 2:14)M2 - 14
90X-RAY DIFFRACTION90chain 'M' and (resseq 15:66)M15 - 66
91X-RAY DIFFRACTION91chain 'M' and (resseq 67:94)M67 - 94
92X-RAY DIFFRACTION92chain 'M' and (resseq 95:119)M95 - 119
93X-RAY DIFFRACTION93chain 'N' and (resseq 2:11)N2 - 11
94X-RAY DIFFRACTION94chain 'N' and (resseq 12:21)N12 - 21
95X-RAY DIFFRACTION95chain 'N' and (resseq 22:31)N22 - 31
96X-RAY DIFFRACTION96chain 'N' and (resseq 32:40)N32 - 40
97X-RAY DIFFRACTION97chain 'N' and (resseq 41:61)N41 - 61
98X-RAY DIFFRACTION98chain 'O' and (resseq 2:49)O2 - 49
99X-RAY DIFFRACTION99chain 'O' and (resseq 50:73)O50 - 73
100X-RAY DIFFRACTION100chain 'O' and (resseq 74:88)O74 - 88
101X-RAY DIFFRACTION101chain 'P' and (resseq 1:8)P1 - 8
102X-RAY DIFFRACTION102chain 'P' and (resseq 9:23)P9 - 23
103X-RAY DIFFRACTION103chain 'P' and (resseq 24:33)P24 - 33
104X-RAY DIFFRACTION104chain 'P' and (resseq 34:52)P34 - 52
105X-RAY DIFFRACTION105chain 'P' and (resseq 53:61)P53 - 61
106X-RAY DIFFRACTION106chain 'P' and (resseq 62:67)P62 - 67
107X-RAY DIFFRACTION107chain 'P' and (resseq 68:76)P68 - 76
108X-RAY DIFFRACTION108chain 'P' and (resseq 77:83)P77 - 83
109X-RAY DIFFRACTION109chain 'Q' and (resseq 2:12)Q2 - 12
110X-RAY DIFFRACTION110chain 'Q' and (resseq 13:17)Q13 - 17
111X-RAY DIFFRACTION111chain 'Q' and (resseq 18:28)Q18 - 28
112X-RAY DIFFRACTION112chain 'Q' and (resseq 29:34)Q29 - 34
113X-RAY DIFFRACTION113chain 'Q' and (resseq 35:45)Q35 - 45
114X-RAY DIFFRACTION114chain 'Q' and (resseq 46:55)Q46 - 55
115X-RAY DIFFRACTION115chain 'Q' and (resseq 56:61)Q56 - 61
116X-RAY DIFFRACTION116chain 'Q' and (resseq 62:81)Q62 - 81
117X-RAY DIFFRACTION117chain 'Q' and (resseq 82:100)Q82 - 100
118X-RAY DIFFRACTION118chain 'R' and (resseq 19:24)R19 - 24
119X-RAY DIFFRACTION119chain 'R' and (resseq 25:36)R25 - 36
120X-RAY DIFFRACTION120chain 'R' and (resseq 37:43)R37 - 43
121X-RAY DIFFRACTION121chain 'R' and (resseq 44:52)R44 - 52
122X-RAY DIFFRACTION122chain 'R' and (resseq 53:59)R53 - 59
123X-RAY DIFFRACTION123chain 'R' and (resseq 60:75)R60 - 75
124X-RAY DIFFRACTION124chain 'R' and (resseq 76:88)R76 - 88
125X-RAY DIFFRACTION125chain 'S' and (resseq 2:12)S2 - 12
126X-RAY DIFFRACTION126chain 'S' and (resseq 13:25)S13 - 25
127X-RAY DIFFRACTION127chain 'S' and (resseq 26:30)S26 - 30
128X-RAY DIFFRACTION128chain 'S' and (resseq 31:40)S31 - 40
129X-RAY DIFFRACTION129chain 'S' and (resseq 41:52)S41 - 52
130X-RAY DIFFRACTION130chain 'S' and (resseq 53:66)S53 - 66
131X-RAY DIFFRACTION131chain 'S' and (resseq 67:71)S67 - 71
132X-RAY DIFFRACTION132chain 'S' and (resseq 72:81)S72 - 81
133X-RAY DIFFRACTION133chain 'T' and (resseq 8:45)T8 - 45
134X-RAY DIFFRACTION134chain 'T' and (resseq 46:75)T46 - 75
135X-RAY DIFFRACTION135chain 'T' and (resseq 76:106)T76 - 106
136X-RAY DIFFRACTION136chain 'U' and (resseq 2:8)U2 - 8
137X-RAY DIFFRACTION137chain 'U' and (resseq 9:25)U9 - 25

+
About Yorodumi

-
News

-
Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

  • Version 3 of the EMDB header file is now the official format.
  • The previous official version 1.9 will be removed from the archive.

Related info.:EMDB header

External links:wwPDB to switch to version 3 of the EMDB data model

-
Aug 12, 2020. Covid-19 info

Covid-19 info

URL: https://pdbj.org/emnavi/covid19.php

New page: Covid-19 featured information page in EM Navigator.

Related info.:Covid-19 info / Mar 5, 2020. Novel coronavirus structure data

+
Mar 5, 2020. Novel coronavirus structure data

Novel coronavirus structure data

Related info.:Yorodumi Speices / Aug 12, 2020. Covid-19 info

External links:COVID-19 featured content - PDBj / Molecule of the Month (242)：Coronavirus Proteases

+
Jan 31, 2019. EMDB accession codes are about to change! (news from PDBe EMDB page)

EMDB accession codes are about to change! (news from PDBe EMDB page)

  • The allocation of 4 digits for EMDB accession codes will soon come to an end. Whilst these codes will remain in use, new EMDB accession codes will include an additional digit and will expand incrementally as the available range of codes is exhausted. The current 4-digit format prefixed with “EMD-” (i.e. EMD-XXXX) will advance to a 5-digit format (i.e. EMD-XXXXX), and so on. It is currently estimated that the 4-digit codes will be depleted around Spring 2019, at which point the 5-digit format will come into force.
  • The EM Navigator/Yorodumi systems omit the EMD- prefix.

Related info.:Q: What is EMD? / ID/Accession-code notation in Yorodumi/EM Navigator

External links:EMDB Accession Codes are Changing Soon! / Contact to PDBj

+
Jul 12, 2017. Major update of PDB

Major update of PDB

  • wwPDB released updated PDB data conforming to the new PDBx/mmCIF dictionary.
  • This is a major update changing the version number from 4 to 5, and with Remediation, in which all the entries are updated.
  • In this update, many items about electron microscopy experimental information are reorganized (e.g. em_software).
  • Now, EM Navigator and Yorodumi are based on the updated data.

External links:wwPDB Remediation / Enriched Model Files Conforming to OneDep Data Standards Now Available in the PDB FTP Archive

-
Yorodumi

Thousand views of thousand structures

  • Yorodumi is a browser for structure data from EMDB, PDB, SASBDB, etc.
  • This page is also the successor to EM Navigator detail page, and also detail information page/front-end page for Omokage search.
  • The word "yorodu" (or yorozu) is an old Japanese word meaning "ten thousand". "mi" (miru) is to see.

Related info.:EMDB / PDB / SASBDB / Comparison of 3 databanks / Yorodumi Search / Aug 31, 2016. New EM Navigator & Yorodumi / Yorodumi Papers / Jmol/JSmol / Function and homology information / Changes in new EM Navigator and Yorodumi

Read more