Entry | Database: PDB / ID: 4cvh |
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Title | Crystal structure of human isoprenoid synthase domain-containing protein |
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Components | ISOPRENOID SYNTHASE DOMAIN-CONTAINING PROTEIN |
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Keywords | TRANSFERASE |
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Function / homology | Function and homology information
cytidylyltransferase activity / D-ribitol-5-phosphate cytidylyltransferase / D-ribitol-5-phosphate cytidylyltransferase activity / protein O-linked mannosylation / isoprenoid biosynthetic process / axon guidance / protein homodimerization activity / cytosolSimilarity search - Function D-ribitol-5-phosphate cytidylyltransferase, C-terminal / D-ribitol-5-phosphate cytidylyltransferase C-terminal domain / 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site / Cytidylyltransferase IspD/TarI / 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. / Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A / Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A / Nucleotide-diphospho-sugar transferases / Alpha-Beta Complex / Alpha BetaSimilarity search - Domain/homology |
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Biological species | HOMO SAPIENS (human) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.39 Å |
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Authors | Kopec, J. / Froese, D.S. / Krojer, T. / Newman, J. / Kiyani, W. / Goubin, S. / Strain-Damerell, C. / Vollmar, M. / von Delft, F. / Burgess-Brown, N. ...Kopec, J. / Froese, D.S. / Krojer, T. / Newman, J. / Kiyani, W. / Goubin, S. / Strain-Damerell, C. / Vollmar, M. / von Delft, F. / Burgess-Brown, N. / Arrowsmith, C. / Edwards, A. / Bountra, C. / Lefeber, D.J. / Yue, W.W. |
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Citation | Journal: Chem.Biol. / Year: 2015 Title: Human Ispd is a Cytidyltransferase Required for Dystroglycan O-Mannosylation. Authors: Riemersma, M. / Froese, D.S. / Van Tol, W. / Engelke, U.F. / Kopec, J. / Van Scherpenzeel, M. / Ashikov, A. / Krojer, T. / von Delft, F. / Tessari, M. / Buczkowska, A. / Swiezewska, E. / ...Authors: Riemersma, M. / Froese, D.S. / Van Tol, W. / Engelke, U.F. / Kopec, J. / Van Scherpenzeel, M. / Ashikov, A. / Krojer, T. / von Delft, F. / Tessari, M. / Buczkowska, A. / Swiezewska, E. / Jae, L.T. / Brummelkamp, T.R. / Manya, H. / Endo, T. / Van Bokhoven, H. / Yue, W.W. / Lefeber, D.J. |
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History | Deposition | Mar 27, 2014 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Feb 4, 2015 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jan 13, 2016 | Group: Database references |
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Revision 1.2 | Jan 24, 2018 | Group: Database references / Category: citation_author / Item: _citation_author.name |
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Revision 1.3 | May 8, 2024 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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