Entry Database : PDB / ID : 3zql Structure visualization Downloads & linksTitle DNA-bound form of TetR-like repressor SimR Components5'-D(*DTP*TP*CP*GP*TP*AP*CP*GP*CP*CP*GP*TP*AP*DCP *GP*AP*A)-3'5'-D(*DTP*TP*CP*GP*TP*AP*CP*GP*GP*CP*GP*TP*AP*DCP *GP*AP*A)-3'PUTATIVE REPRESSOR SIMREG2 DetailsKeywords PROTEIN-DNA COMPLEX / ANTIBIOTIC RESISTANCE / TETR-LIKE PROTEINS / TRANSCRIPTIONAL REGULATION / STREPTOMYCESFunction / homology Function and homology informationFunction Domain/homology Component
transcription cis-regulatory region binding / DNA-binding transcription factor activity / negative regulation of DNA-templated transcription / metal ion binding Similarity search - Function Tetracycline repressor TetR, C-terminal / Tetracyclin repressor-like, C-terminal domain / Tetracycline Repressor, domain 2 / Tetracyclin repressor-like, C-terminal domain superfamily / Tetracycline Repressor; domain 2 / Bacterial regulatory proteins, tetR family / DNA-binding HTH domain, TetR-type / TetR-type HTH domain profile. / Homeodomain-like / Homeobox-like domain superfamily ... Tetracycline repressor TetR, C-terminal / Tetracyclin repressor-like, C-terminal domain / Tetracycline Repressor, domain 2 / Tetracyclin repressor-like, C-terminal domain superfamily / Tetracycline Repressor; domain 2 / Bacterial regulatory proteins, tetR family / DNA-binding HTH domain, TetR-type / TetR-type HTH domain profile. / Homeodomain-like / Homeobox-like domain superfamily / Arc Repressor Mutant, subunit A / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homologyBiological species STREPTOMYCES ANTIBIOTICUS (bacteria)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.99 Å DetailsAuthors Le, T.B.K. / Schumacher, M.A. / Lawson, D.M. / Brennan, R.G. / Buttner, M.J. CitationJournal : Nucleic Acids Res. / Year : 2011Title : The Crystal Structure of the Tetr Family Transcriptional Repressor Simr Bound to DNA and the Role of a Flexible N-Terminal Extension in Minor Groove Binding.Authors : Le, T.B.K. / Schumacher, M.A. / Lawson, D.M. / Brennan, R.G. / Buttner, M.J. History Deposition Jun 10, 2011 Deposition site : PDBE / Processing site : PDBERevision 1.0 Aug 31, 2011 Provider : repository / Type : Initial releaseRevision 1.1 Dec 7, 2011 Group : Database referencesRevision 1.2 May 8, 2019 Group : Data collection / Experimental preparation / OtherCategory : database_PDB_rev / database_PDB_rev_record ... database_PDB_rev / database_PDB_rev_record / exptl_crystal_grow / pdbx_database_proc / pdbx_database_status / pdbx_seq_map_depositor_info Item : _exptl_crystal_grow.method / _pdbx_database_status.recvd_author_approval / _pdbx_seq_map_depositor_info.one_letter_code_modRevision 1.3 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_ncs_dom_lim Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id
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