登録情報 | データベース: PDB / ID: 3w0l |
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タイトル | The crystal structure of Xenopus Glucokinase and Glucokinase Regulatory Protein complex |
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要素 | - Glucokinase
- Glucokinase regulatory protein
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キーワード | TRANSFERASE/TRANSFERASE INHIBITOR / aba sandwich / typical hexokanse fold / kinase / sugar binding / TRANSFERASE-TRANSFERASE INHIBITOR complex |
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機能・相同性 | 機能・相同性情報
hexose metabolic process / detection of glucose / negative regulation of glucokinase activity / fructose-6-phosphate binding / carbohydrate derivative metabolic process / 転移酵素; リンを含む基を移すもの; キナーゼ(アルコールにつなげるもの) / glucokinase activity / D-glucose binding / intracellular glucose homeostasis / positive regulation of glycogen biosynthetic process ...hexose metabolic process / detection of glucose / negative regulation of glucokinase activity / fructose-6-phosphate binding / carbohydrate derivative metabolic process / 転移酵素; リンを含む基を移すもの; キナーゼ(アルコールにつなげるもの) / glucokinase activity / D-glucose binding / intracellular glucose homeostasis / positive regulation of glycogen biosynthetic process / negative regulation of gluconeogenesis / glycolytic process / positive regulation of insulin secretion / glucose homeostasis / carbohydrate metabolic process / mitochondrion / nucleoplasm / ATP binding / cytoplasm類似検索 - 分子機能 Rossmann fold - #12620 / Hexokinase-4, chordate / Helicase, Ruva Protein; domain 3 - #1080 / Glucokinase regulatory protein, conserved site / N-acetylmuramic acid 6-phosphate etherase/glucokinase regulatory protein / Glucokinase regulatory protein family signature. / Hexokinase; domain 1 / Hexokinase; domain 1 - #20 / Hexokinase / Hexokinase, binding site ...Rossmann fold - #12620 / Hexokinase-4, chordate / Helicase, Ruva Protein; domain 3 - #1080 / Glucokinase regulatory protein, conserved site / N-acetylmuramic acid 6-phosphate etherase/glucokinase regulatory protein / Glucokinase regulatory protein family signature. / Hexokinase; domain 1 / Hexokinase; domain 1 - #20 / Hexokinase / Hexokinase, binding site / Hexokinase, N-terminal / Hexokinase, C-terminal / Hexokinase / Hexokinase / Hexokinase domain signature. / Hexokinase domain profile. / SIS domain / SIS domain profile. / Glucose-6-phosphate isomerase like protein; domain 1 / ATPase, nucleotide binding domain / Helicase, Ruva Protein; domain 3 / ATPase, nucleotide binding domain / Nucleotidyltransferase; domain 5 / Rossmann fold / 2-Layer Sandwich / Orthogonal Bundle / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 FRUCTOSE -6-PHOSPHATE / Phosphotransferase / Glucokinase regulatory protein類似検索 - 構成要素 |
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生物種 | Xenopus laevis (アフリカツメガエル) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.92 Å |
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データ登録者 | Choi, J.M. / Seo, M.H. / Kyeong, H.H. / Kim, E. / Kim, H.S. |
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引用 | ジャーナル: Proc.Natl.Acad.Sci.USA / 年: 2013 タイトル: Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase 著者: Choi, J.M. / Seo, M.H. / Kyeong, H.H. / Kim, E. / Kim, H.S. |
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履歴 | 登録 | 2012年10月31日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2013年7月17日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年11月8日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_label_asym_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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