登録情報 | データベース: PDB / ID: 3vgx |
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タイトル | Structure of gp41 T21/Cp621-652 |
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要素 | (Envelope glycoprotein gp160) x 2 |
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キーワード | MEMBRANE PROTEIN / 6-helix bundle / membrane fusion |
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機能・相同性 | 機能・相同性情報
host cell periphery / CD4 receptor binding / Dectin-2 family / positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / host cell endosome membrane / clathrin-dependent endocytosis of virus by host cell / host cell perinuclear region of cytoplasm / viral protein processing ...host cell periphery / CD4 receptor binding / Dectin-2 family / positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / host cell endosome membrane / clathrin-dependent endocytosis of virus by host cell / host cell perinuclear region of cytoplasm / viral protein processing / fusion of virus membrane with host plasma membrane / virus-mediated perturbation of host defense response / fusion of virus membrane with host endosome membrane / viral envelope / protein-containing complex binding / virion attachment to host cell / host cell plasma membrane / structural molecule activity / virion membrane / membrane類似検索 - 分子機能 Envelope glycoprotein Gp160 / Retroviral envelope protein / Retroviral envelope protein GP41-like / Gp120 core superfamily / Envelope glycoprotein GP120 / Human immunodeficiency virus 1, envelope glycoprotein Gp120類似検索 - ドメイン・相同性 ACETIC ACID / Envelope glycoprotein gp160 / Envelope glycoprotein gp160類似検索 - 構成要素 |
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生物種 | ![](img/tx_virus.gif) Human immunodeficiency virus type 1 (ヒト免疫不全ウイルス) |
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手法 | X線回折 / 分子置換 / 解像度: 1.74 Å |
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データ登録者 | Yao, X. / Waltersperger, S. / Wang, M. / Cui, S. |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2012 タイトル: Discovery of critical residues for viral entry and inhibition through structural Insight of HIV-1 fusion inhibitor CP621-652. 著者: Chong, H. / Yao, X. / Qiu, Z. / Qin, B. / Han, R. / Waltersperger, S. / Wang, M. / Cui, S. / He, Y. |
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履歴 | 登録 | 2011年8月22日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2012年4月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2013年6月26日 | Group: Database references |
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改定 1.2 | 2023年11月8日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_special_symmetry / struct_conn / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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