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Structure paper

TitleDiscovery of critical residues for viral entry and inhibition through structural Insight of HIV-1 fusion inhibitor CP621-652.
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 20281-20289, Year 2012
Publish dateAug 22, 2011 (structure data deposition date)
AuthorsChong, H. / Yao, X. / Qiu, Z. / Qin, B. / Han, R. / Waltersperger, S. / Wang, M. / Cui, S. / He, Y.
External linksJ. Biol. Chem. / PubMed:22511760
MethodsX-ray diffraction
Resolution1.74 Å
Structure data

PDB-3vgx:
Structure of gp41 T21/Cp621-652
Method: X-RAY DIFFRACTION / Resolution: 1.74 Å

Chemicals

ChemComp-ACY:
ACETIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus type 1
KeywordsMEMBRANE PROTEIN / 6-helix bundle / membrane fusion

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