登録情報 データベース : PDB / ID : 3v2y 構造の表示 ダウンロードとリンクタイトル Crystal Structure of a Lipid G protein-Coupled Receptor at 2.80A 要素Sphingosine 1-phosphate receptor 1, Lysozyme chimera (E.C.3.2.1.17) 詳細 キーワード HYDROLASE / sphingosine / EDG receptor / lipid receptor / multiple sclerosis / autoimmunity / Structural Genomics / PSI-Biology / GPCR Network / GPCR / membrane protein / G protein coupled receptor / membrane機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
cardiac muscle tissue growth involved in heart morphogenesis / sphingolipid binding / blood vessel maturation / sphingosine-1-phosphate receptor activity / Lysosphingolipid and LPA receptors / T cell migration / endothelial cell differentiation / heart trabecula morphogenesis / regulation of metabolic process / regulation of bone mineralization ... cardiac muscle tissue growth involved in heart morphogenesis / sphingolipid binding / blood vessel maturation / sphingosine-1-phosphate receptor activity / Lysosphingolipid and LPA receptors / T cell migration / endothelial cell differentiation / heart trabecula morphogenesis / regulation of metabolic process / regulation of bone mineralization / sphingosine-1-phosphate receptor signaling pathway / leukocyte chemotaxis / regulation of bone resorption / positive regulation of positive chemotaxis / negative regulation of stress fiber assembly / lamellipodium assembly / transmission of nerve impulse / regulation of cell adhesion / viral release from host cell by cytolysis / adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway / peptidoglycan catabolic process / G protein-coupled receptor activity / G protein-coupled receptor binding / positive regulation of smooth muscle cell proliferation / neuron differentiation / adenylate cyclase-activating G protein-coupled receptor signaling pathway / brain development / chemotaxis / cell wall macromolecule catabolic process / cell migration / lysozyme / lysozyme activity / phospholipase C-activating G protein-coupled receptor signaling pathway / actin cytoskeleton organization / angiogenesis / Interleukin-4 and Interleukin-13 signaling / cell population proliferation / host cell cytoplasm / Potential therapeutics for SARS / cell adhesion / endosome / positive regulation of cell migration / defense response to bacterium / membrane raft / G protein-coupled receptor signaling pathway / external side of plasma membrane / intracellular membrane-bounded organelle / positive regulation of transcription by RNA polymerase II / nucleoplasm / plasma membrane / cytoplasm 類似検索 - 分子機能 EDG-1 sphingosine 1-phosphate receptor / Sphingosine 1-phosphate receptor / Rhopdopsin 7-helix transmembrane proteins / Rhodopsin 7-helix transmembrane proteins / Lysozyme - #40 / Endolysin T4 type / T4-type lysozyme / Glycoside hydrolase, family 24 / Lysozyme domain superfamily / Phage lysozyme ... EDG-1 sphingosine 1-phosphate receptor / Sphingosine 1-phosphate receptor / Rhopdopsin 7-helix transmembrane proteins / Rhodopsin 7-helix transmembrane proteins / Lysozyme - #40 / Endolysin T4 type / T4-type lysozyme / Glycoside hydrolase, family 24 / Lysozyme domain superfamily / Phage lysozyme / Serpentine type 7TM GPCR chemoreceptor Srsx / Lysozyme / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM / G-protein coupled receptors family 1 profile. / 7 transmembrane receptor (rhodopsin family) / Lysozyme-like domain superfamily / Up-down Bundle / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 Chem-ML5 / Endolysin / Sphingosine 1-phosphate receptor 1 類似検索 - 構成要素生物種 Homo sapiens (ヒト) Enterobacteria phage T4 (ファージ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.8 Å 詳細データ登録者 Hanson, M.A. / Roth, C.B. / Jo, E. / Griffith, M.T. / Scott, F.L. / Reinhart, G. / Desale, H. / Clemons, B. / Cahalan, S.M. / Schuerer, S.C. ...Hanson, M.A. / Roth, C.B. / Jo, E. / Griffith, M.T. / Scott, F.L. / Reinhart, G. / Desale, H. / Clemons, B. / Cahalan, S.M. / Schuerer, S.C. / Sanna, M.G. / Han, G.W. / Kuhn, P. / Rosen, H. / Stevens, R.C. / GPCR Network (GPCR) 引用ジャーナル : Science / 年 : 2012タイトル : Crystal structure of a lipid G protein-coupled receptor.著者 : Hanson, M.A. / Roth, C.B. / Jo, E. / Griffith, M.T. / Scott, F.L. / Reinhart, G. / Desale, H. / Clemons, B. / Cahalan, S.M. / Schuerer, S.C. / Sanna, M.G. / Han, G.W. / Kuhn, P. / Rosen, H. / Stevens, R.C. 履歴 登録 2011年12月12日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2012年2月15日 Provider : repository / タイプ : Initial release改定 1.1 2012年3月14日 Group : Database references改定 1.2 2017年6月21日 Group : Data collection / Database references ... Data collection / Database references / Source and taxonomy / Structure summary カテゴリ : diffrn_radiation_wavelength / entity ... diffrn_radiation_wavelength / entity / entity_name_com / entity_src_gen / struct_ref / struct_ref_seq_dif Item : _entity.pdbx_description / _entity_name_com.name ... _entity.pdbx_description / _entity_name_com.name / _struct_ref.db_code / _struct_ref.pdbx_seq_one_letter_code 改定 1.3 2020年7月29日 Group : Data collection / Derived calculations / Structure summaryカテゴリ : chem_comp / entity ... chem_comp / entity / pdbx_chem_comp_identifier / pdbx_entity_nonpoly / struct_conn / struct_site / struct_site_gen Item : _chem_comp.name / _chem_comp.type ... _chem_comp.name / _chem_comp.type / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.pdbx_role 解説 : Carbohydrate remediation / Provider : repository / タイプ : Remediation改定 1.4 2024年4月3日 Group : Data collection / Database references ... Data collection / Database references / Refinement description / Structure summary カテゴリ : chem_comp / chem_comp_atom ... chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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